#CureSearch
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sailorrooscout.bsky.social
30 to 60 days typical for dogs with the condition.

The next step, through support from the FDA and the CureSearch for Children's Cancer foundation, will be an expanded Phase I clinical trial to include up to 24 adult and pediatric patients to validate the findings.
May 7, 2024 at 5:05 PM
sailorrooscout.bsky.social
This is NOW in early HUMAN trials.
• www.sciencedaily.com/releases/202...
• www.livescience.com/health/cance...

The study has been published in Nature Biomedical Engineering. YES, it is PEER-REVIEWED.
• www.nature.com/articles/s41...

🧪🧵⬇️
ABSTRACT The success of cancer immunotherapies is predicated on the targeting of highly expressed neoepitopes, which preferentially favours malignancies with high mutational burden. Here we show that early responses by type-l interferons mediate the success of immune checkpoint inhibitors as well as epitope spreading in poorly immunogenic tumours and that these interferon responses can be enhanced via systemic administration of lipid particles loaded with RNA coding for tumour-unspecific antigens. In mice, the immune responses of tumours sensitive to checkpoint inhibitors were transferable to resistant tumours and resulted in heightened immunity with antigenic spreading that protected the animals from tumour rechallenge. Our findings show that the resistance of tumours to immunotherapy is dictated by the absence of a damage response, which can be restored by boosting early type-I interferon responses to enable epitope spreading and self-amplifying responses in treatment-refractory tumours. This work was supported by federal awards W81XWH-17-1-0510, KO8CA199224, R37CA251978, R01CA266857, R01FD007268 (FDA - OOPD, Office of Orphan Products Development), and P30CA247796; Florida Department of Health 20B11 (Bankhead Coley) and 20L07 (Live Like Bella) awards; and foundation grants from CureSearch (Catapult Award), Alex's Lemonade Stand (R Accelerated Award), Rally Foundation, Hyundai Hope on Wheels (Hope Scholar Award), Stop Children's Cancer and the Bonnie R. Freeman Professorship for Pediatric Oncology Research, Danny's Dream, the Medulloblastoma Initiative (MBI) and Cure Group 4 Medulloblastoma Consortium, lans Friends Foundation, and the National Pediatric Cancer Foundation.
August 21, 2025 at 4:01 PM
johnprensner.bsky.social
Thank you so much to #CureSearch for supporting our work to find 🔎 #microproteins in #ATRT, an often fatal #braincancer in children. This awful disease is most common in the youngest kids - those less than 3 years old.

Not sure what #ATRT is?

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🧬 💻
#PEDSky
#CANSky

curesearch.org/unlocking-ho...
Unlocking Hope for Children with Aggressive Brain Tumors: Meet Dr. John Prensner
A Life-Changing Diagnosis At just three years old, most toddlers are learning to run, jump, and explore the world with unbridled curiosity. But for some, these precious milestones are interrupted by a...
curesearch.org
December 22, 2024 at 2:05 AM
bamboozledgaming.bsky.social
@everyone we are Live on the TikTok!!! Time to raise money for Curesearch!!!!

www.tiktok.com/t/ZTHscUuajW...
Bamboozled_Gaming🎗️ (@bamboozled_gaming) is LIVE - TikTok LIVE
Curesearch Fundraiser | Watch Bamboozled_Gaming🎗️ (@bamboozled_gaming)'s LIVE on TikTok and interact with others in real time.
www.tiktok.com
August 14, 2025 at 1:29 PM
misfitdollies.bsky.social
So this is Brave Ken and apparently he’s going to be given for free to kids struggling with cancer & can be requested on the website curesearch according to @/a_plastic_tan_2 on IG. They’ve done dolls like this before and I think it’s really nice that they’re offered for free #dollsky
A Ken doll in a box with a bald head, white skin, blue eyes and a smile. He has a blue and white striped shirt and green shorts. He wears a beaded bracelet on his wrist. He also has a blonde wig, a blue baseball cap with “love” written on it in red letters, headphones and a green fabric beanie. There is art of him on the blox featuring Malibu Barbie and Brooklyn Barbie beside him, one where they’re wearing wigs and one where they’re wearing hats. The box is pink with “Barbie” and “You are brave. You are strong. You are beautiful.” Written on it.
August 27, 2025 at 3:59 AM
sam-blackman.bsky.social
Important work given profound unmet need and available drugs in phase 1 trials. #dipg @BrainTumourOrg #epigenetics @CureSearch https://twitter.com/dannisvv/status/836467742526091264
December 1, 2024 at 10:44 PM
andrei-thomas-t.bsky.social
3.5 years ago, we knew very little about #pediatric high-grade #glioma... our strengths were the working knowledge of #mRNA #splicing & #microexons and the ability to put together amazing teams of collaborators. Somehow, CureSearch for Children's Cancer had faith in us! www.cell.com/cell-reports...
NRCAM variant defined by microexon skipping is a targetable cell surface proteoform in high-grade gliomas
Aberrant splicing of microexons yields non-canonical surface receptors, such as the neuronal cell adhesion molecule (NRCAM) lacking amino acids encoded by exons 5 and 19. Sehgal et al. show that Δex5Δ...
www.cell.com
August 8, 2025 at 3:30 PM
bamboozledgaming.bsky.social
@everyone It’s that time of year again !!!! We raise money for pediatric cancer research !!!!! Through Curesearch we will be raising money as a team to donate !!! Spread the word!

give.curesearch.org/give/t762976...
2025 Salt Lake City Walk
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give.curesearch.org
August 13, 2025 at 11:19 PM
cugynonc.bsky.social
STEM Poster Day at the Capitol – Today (3/11/2025)

Join CU Anschutz scientists from fields such as cancer research, biology, biochemistry, neurology, and transportation as they showcase their groundbreaking work at the Colorado State Capitol. #CUAnschutz #CUResearch

www.denver.org/event/stem-p...
STEM Poster Day at the Capitol
Join us for an exciting opportunity to connect with scientists from across Colorado and discover the cutting-edge STEM research happening right here in our state! This engaging, jargon-free event is p...
www.denver.org
March 11, 2025 at 8:59 PM
cuobgynedu.bsky.social
🌸 Spring into Health: Tips for Maintaining Gynecologic Health 🌸

Early detection of ovarian cancer can save lives!

Consult a CU gynecologic oncologist: (303) 724-2066
For research insights, visit loom.ly/FXnaTN0

#OvarianCancerAwareness #SpringIntoHealth #WomensHealth #EarlyDetection #CUResearch
Ovarian Cancer Ovarian cancer broadly refers to cancer that starts in the ovaries, fallopian tubes, or the lining of the abdominal cavity, called the peritoneum. Know the Symptoms • Abdominal swelling or bloating. • Feeling full quickly when eating or trouble eating. Weight loss. • Pain in the stomach or pelvic area. • Constipation or other changes in bowel habits. • A frequent or urgent need to urinate. Risk Factors • Age: Most common in women ages 50 to 60. • Inherited gene mutations: BRCA1, BRCA2, and Lynch syndrome mutations increase risk. • Family history: Increased risk if two or more close relatives have ovarian cancer. • Estrogen hormone replacement therapy: Long-term or high-dose use may increase risk. • Menstruation and menopause timing: Women who started menstruating at an early or late age may be at increased risk. Detect it Early • Annual women's health visits are essential. If a family member has cancer, discuss monitoring options with your doctor. • Ask for a pelvic exam, transvaginal ultrasound, and/or a CA-125 blood test if symptoms arise.
April 9, 2025 at 9:55 PM
sam-blackman.bsky.social
Thrilled to be able to participate in #cac2summit2018 on behalf of @CureSearch, #ACCELERATE, and as a pediatric oncologist working in biotech R&D!
December 2, 2024 at 8:28 PM
sam-blackman.bsky.social
In case he doesn’t tweet it, I will. Congratulations @ranjitbindra ! Congratulations to @CureSearch for picking a great project to support.
December 2, 2024 at 8:27 PM
sam-blackman.bsky.social
Hey BioTwitter ... it’s @ranjitbindra and @drsam hanging out at @CureSearch Catapult 2018. (I think @LeeHelmanLA is around here somewhere ...)
December 2, 2024 at 8:27 PM
sam-blackman.bsky.social
Also, @CureSearch is so lucky to have Dr. O’Reilly as the head of their Scientific Advisory Board! https://twitter.com/drsdnimer/status/867333651318657024
December 1, 2024 at 11:03 PM
sam-blackman.bsky.social
Heard this fantastic scientific story last week at @CureSearch Catapult meeting. Congrats to Ranjit Bindra and his lab. @ranjitbindra https://twitter.com/roelverhaak/status/837311868666544129
December 1, 2024 at 10:45 PM
sam-blackman.bsky.social
cc @BrainTumourCEO @BrainTumourOrg @CureSearch https://twitter.com/dannisvv/status/823106440982302720
December 1, 2024 at 10:44 PM
lgoodbu.bsky.social
oncodaily.com/voices/oncog...
Semiramida Markosyan: Stay Updated on Cancer Grants and Fellowships with OncoGrants by OncoDaily - OncoDaily
Semiramida Markosyan: Stay Updated on Cancer Grants and Fellowships with OncoGrants by OncoDaily / cancer, CureSearch for Children's Cancer, OncoDaily,
oncodaily.com
March 21, 2026 at 8:11 PM
longtail-news.bsky.social
Feed: "Oncology News, Insights, Stories by OncoDaily"
Published on Sunday, February 1, 2026
Kay Koehler: 9 Years of Building Impact at CureSearch for Children’s Cancer
Kay Koehler: 9 Years of Building Impact at CureSearch for Children’s Cancer / cancer, children's cancer, CureSearch, CureSearch for Children's Cancer, Kay
oncodaily.com
February 2, 2026 at 5:46 AM
timothymdean.bsky.social
It’s time to start fundraising again.This will be my 6th Ultimate Hike to support CureSearch and their mission to cure pediatric cancer. Your donations can really help kids with cancer.

give.curesearch.org/timdean2025
February 16, 2025 at 7:34 PM
citylifejc.bsky.social
Hate watching Entourage with @wendymolyneux to fight leukemia @curesearch (@ TCL Chinese Multiplex in Hollywood, CA

swarmapp.com/c/4O1gJNa60GL
Jeremy | TCL Chinese Theatre
Get out. Explore. Download Swarm and live your life more checked in.
www.swarmapp.com
March 18, 2025 at 3:25 AM