Congratulations to our PhD Student Melany Villegas-Valencia, who defended last week. Her work was foundational to our engineering efforts in Cyanidioschyzon merolae.
November 21, 2025 at 7:47 AM
Congratulations to our PhD Student Melany Villegas-Valencia, who defended last week. Her work was foundational to our engineering efforts in Cyanidioschyzon merolae.
Congratulations to our great team led by Tim Stephens and Julia Van Etten for publishing this wonderful paper about how microalgae and microbes interact at Yellowstone National Park to maintain stable ecosystems.(academic.oup.com/ismecommun/a...). @couchmicroscopy.bsky.social @apmweber.bsky.social
January 17, 2025 at 7:41 PM
Congratulations to our great team led by Tim Stephens and Julia Van Etten for publishing this wonderful paper about how microalgae and microbes interact at Yellowstone National Park to maintain stable ecosystems.(academic.oup.com/ismecommun/a...). @couchmicroscopy.bsky.social @apmweber.bsky.social
Genome Position Does Not Impact Transgene Expression Efficiency in the Ancient Red Alga Cyanidioschyzon merolae https://www.biorxiv.org/content/10.64898/2026.01.31.703004v1
February 1, 2026 at 4:02 AM
Genome Position Does Not Impact Transgene Expression Efficiency in the Ancient Red Alga Cyanidioschyzon merolae https://www.biorxiv.org/content/10.64898/2026.01.31.703004v1
Structural proteomics reveals the functional docking interface of ferredoxin‐NADP+ reductase on photosystem I in the red alga Cyanidioschyzon merolae onlinelibrary.wiley.com/doi/10.1111/... @theplantjournal.bsky.social
onlinelibrary.wiley.com
July 2, 2026 at 2:43 AM
Structural proteomics reveals the functional docking interface of ferredoxin‐NADP+ reductase on photosystem I in the red alga Cyanidioschyzon merolae onlinelibrary.wiley.com/doi/10.1111/... @theplantjournal.bsky.social
NEWS & VIEWS: Metabolic modeling suggested non-canonical algal carbon concentrating mechanism in Cyanidioschyzon merolae (Maneesh Lingwan) https://doi.org/10.1093/plphys/kiaf019 #PlantScience
January 27, 2025 at 1:57 PM
NEWS & VIEWS: Metabolic modeling suggested non-canonical algal carbon concentrating mechanism in Cyanidioschyzon merolae (Maneesh Lingwan) https://doi.org/10.1093/plphys/kiaf019 #PlantScience
Great work by Komiya, Pancha et al. (2025) on how #PlantTOR signaling regulates (floridean) starch degradation in extremophilic red microalga #Cyanidioschyzon merolae (rapamycin-sensitive SF12 strain), by modulating the phosphorylation status of α-glucan, water dikinase (CmGWD) at Ser264 residue.
Target of rapamycin signaling regulates starch degradation via α-glucan, water dikinase in a unicellular red alga academic.oup.com/plphys/artic... @plantphys.bsky.social
Target of rapamycin signaling regulates starch degradation via α-glucan, water dikinase in a unicellular red alga
Target of rapamycin signaling enhances starch contents by regulating the activity of α-glucan, water dikinase, through changing its phosphorylation status
academic.oup.com
March 21, 2025 at 8:48 PM
Great work by Komiya, Pancha et al. (2025) on how #PlantTOR signaling regulates (floridean) starch degradation in extremophilic red microalga #Cyanidioschyzon merolae (rapamycin-sensitive SF12 strain), by modulating the phosphorylation status of α-glucan, water dikinase (CmGWD) at Ser264 residue.
In their Tools and Resources article, Yuko Mogi, Yamato Yoshida and colleagues present their recombinant protein expression platform with simplified purification based on the photosynthetic unicellular red alga Cyanidioschyzon merolae.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
March 4, 2026 at 4:20 PM
In their Tools and Resources article, Yuko Mogi, Yamato Yoshida and colleagues present their recombinant protein expression platform with simplified purification based on the photosynthetic unicellular red alga Cyanidioschyzon merolae.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
“We isolated photosynthetically active chloroplasts from the primitive red alga Cyanidioschyzon merolae and incorporated them in cultured mammalian cells. The incorporated chloroplasts maintained electron transport activity of photosystem II in cultured mammalian cells for at least 2 days.”
Incorporation of photosynthetically active algal chloroplasts in cultured mammalian cells towards photosynthesis in animals
Chloroplasts are photosynthetic organelles that evolved through the endosymbiosis between cyanobacteria-like symbionts and hosts. Many studies have at …
www.jstage.jst.go.jp
February 14, 2025 at 12:34 PM
“We isolated photosynthetically active chloroplasts from the primitive red alga Cyanidioschyzon merolae and incorporated them in cultured mammalian cells. The incorporated chloroplasts maintained electron transport activity of photosystem II in cultured mammalian cells for at least 2 days.”
Genome Position Does Not Impact Transgene Expression Efficiency in the Ancient Red Alga Cyanidioschyzon merolae https://www.biorxiv.org/content/10.64898/2026.01.31.703004v1
February 1, 2026 at 4:02 AM
Genome Position Does Not Impact Transgene Expression Efficiency in the Ancient Red Alga Cyanidioschyzon merolae https://www.biorxiv.org/content/10.64898/2026.01.31.703004v1
IPTG- and estradiol-inducible gene expression systems in the unicellular red alga Cyanidioschyzon merolae (Takayuki Fujiwara , Shunsuke Hirooka , Shota Yamashita , Shin-ya Miyagishima) doi.org/10.1093/plph... #PlantScience @aspbofficial
IPTG- and estradiol-inducible gene expression systems in the unicellular red alga Cyanidioschyzon merolae
Controllable gene expression and protein levels in a red alga provide powerful tools for studying photosynthetic eukaryotes.
doi.org
January 30, 2026 at 6:13 PM
IPTG- and estradiol-inducible gene expression systems in the unicellular red alga Cyanidioschyzon merolae (Takayuki Fujiwara , Shunsuke Hirooka , Shota Yamashita , Shin-ya Miyagishima) doi.org/10.1093/plph... #PlantScience @aspbofficial
Atypical absorption response to the trans-thylakoid electric field in the acidothermophilic red algae Cyanidioschyzon merolae and Galdieria partita pubmed.ncbi.nlm.nih.gov/39924096/
February 10, 2025 at 8:15 AM
Atypical absorption response to the trans-thylakoid electric field in the acidothermophilic red algae Cyanidioschyzon merolae and Galdieria partita pubmed.ncbi.nlm.nih.gov/39924096/
🍀 Éirinn go Brách! 🍀 Happy St. Patrick's Day! 🍀
Fairy puke lichen from Hoh Rain Forest, Olympic National Park.
Cyanidioschyzon algae from Whirligig Geyser, Yellowstone National Park.
American alligator from sawgrass marsh, Everglades National Park.
Fairy puke lichen from Hoh Rain Forest, Olympic National Park.
Cyanidioschyzon algae from Whirligig Geyser, Yellowstone National Park.
American alligator from sawgrass marsh, Everglades National Park.
March 17, 2025 at 7:41 PM
🍀 Éirinn go Brách! 🍀 Happy St. Patrick's Day! 🍀
Fairy puke lichen from Hoh Rain Forest, Olympic National Park.
Cyanidioschyzon algae from Whirligig Geyser, Yellowstone National Park.
American alligator from sawgrass marsh, Everglades National Park.
Fairy puke lichen from Hoh Rain Forest, Olympic National Park.
Cyanidioschyzon algae from Whirligig Geyser, Yellowstone National Park.
American alligator from sawgrass marsh, Everglades National Park.
Very nice 'news & views' write-up about the C. merolae modeling work @anne-steensma.bsky.social, me, and our wonderful co-authors presented in Plant Phys: doi.org/10.1093/plph...
Metabolic modeling suggested non-canonical algal carbon concentrating mechanism in Cyanidioschyzon merolae
Maneesh Lingwan; Metabolic modeling suggested non-canonical algal carbon concentrating mechanism in Cyanidioschyzon merolae, Plant Physiology, , kiaf019, h
doi.org
January 20, 2025 at 5:00 PM
Very nice 'news & views' write-up about the C. merolae modeling work @anne-steensma.bsky.social, me, and our wonderful co-authors presented in Plant Phys: doi.org/10.1093/plph...
Red alga cyanidioschyzon (more established than all of the above, but still a cool branch of life and model, or a hot one I guess).: pubmed.ncbi.nlm.nih.gov/33836072/
The Unicellular Red Alga Cyanidioschyzon merolae-The Simplest Model of a Photosynthetic Eukaryote - PubMed
Several species of unicellular eukaryotic algae exhibit relatively simple genomic and cellular architecture. Laboratory cultures of these algae grow faster than plants and often provide homogeneous ce...
pubmed.ncbi.nlm.nih.gov
November 25, 2024 at 8:45 PM
Red alga cyanidioschyzon (more established than all of the above, but still a cool branch of life and model, or a hot one I guess).: pubmed.ncbi.nlm.nih.gov/33836072/
RRIDs were included in this International Journal of Molecular Sciences paper. We value the author's support of reproducibility. #RRID #ReproducibleResearch #STMpublishing
Transcriptomics Reveals an Energy-Saving Metabolic Switch in an Extremophilic Red Microalga Cyanidioschyzon merolae Under Nickel Stress
doi.org
May 27, 2025 at 7:01 AM
RRIDs were included in this International Journal of Molecular Sciences paper. We value the author's support of reproducibility. #RRID #ReproducibleResearch #STMpublishing
That's 100% a cyanobacterium. Phycocyanin is a water soluble blue pigment. I am not aware of any green algae which retained it in evolution (maybe someone here does). The Red algae did though, that's why Cyanidioschyzon merolae and Galdieria are interesting for its production.
December 24, 2024 at 1:57 PM
That's 100% a cyanobacterium. Phycocyanin is a water soluble blue pigment. I am not aware of any green algae which retained it in evolution (maybe someone here does). The Red algae did though, that's why Cyanidioschyzon merolae and Galdieria are interesting for its production.
Incorporation of photosynthetically active algal chloroplasts in cultured mammalian cells towards photosynthesis in animals (OA)
https://botany.fyi/foauuj
Aoki et al. isolated photosynthetically active chloroplasts from the primitive red alga Cyanidioschyzon merolae and incorporated them in
https://botany.fyi/foauuj
Aoki et al. isolated photosynthetically active chloroplasts from the primitive red alga Cyanidioschyzon merolae and incorporated them in
Incorporation of photosynthetically active algal chloroplasts in cultured mammalian cells towards photosynthesis in animals
Chloroplasts are photosynthetic organelles that evolved through the endosymbiosis between cyanobacteria-like symbionts and hosts. Many studies have at …
botany.fyi
November 6, 2024 at 12:30 AM
Incorporation of photosynthetically active algal chloroplasts in cultured mammalian cells towards photosynthesis in animals (OA)
https://botany.fyi/foauuj
Aoki et al. isolated photosynthetically active chloroplasts from the primitive red alga Cyanidioschyzon merolae and incorporated them in
https://botany.fyi/foauuj
Aoki et al. isolated photosynthetically active chloroplasts from the primitive red alga Cyanidioschyzon merolae and incorporated them in
Volcanic #hot_springs-dwelling #algae reveal #photosynthetic insights
#thermophiles #Cyanidioschyzon #carbon_concentrating_mechanism #CCM
phys.org/news/2025-02...
#thermophiles #Cyanidioschyzon #carbon_concentrating_mechanism #CCM
phys.org/news/2025-02...
Volcanic hot springs-dwelling algae reveal photosynthetic insights
Italy's Phlegraean Fields is a hotspot of volcanic activity—an ever-shifting landscape pocketed with acidic hot springs. This huge caldera is a part of the Campanian volcanic arc, which includes Mount...
phys.org
February 7, 2025 at 5:37 PM
Systematic evaluation of Cyanidioschyzon merolae across photobioreactor systems: Linking reactor design to biomass production and biochemical composition #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.06.17.732901v1
https://www.biorxiv.org/content/10.64898/2026.06.17.732901v1
June 18, 2026 at 7:00 AM
Systematic evaluation of Cyanidioschyzon merolae across photobioreactor systems: Linking reactor design to biomass production and biochemical composition #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.06.17.732901v1
https://www.biorxiv.org/content/10.64898/2026.06.17.732901v1
Research into the ancient red alga Cyanidioschyzon merolae reveals that genome position has minimal impact on transgene expression efficiency, a significant finding for synthetic biology advancements.
🔗 Source: https://pubmed.ncbi.nlm.nih.gov/42107704/
🔗 Source: https://pubmed.ncbi.nlm.nih.gov/42107704/
May 26, 2026 at 2:54 AM
Research into the ancient red alga Cyanidioschyzon merolae reveals that genome position has minimal impact on transgene expression efficiency, a significant finding for synthetic biology advancements.
🔗 Source: https://pubmed.ncbi.nlm.nih.gov/42107704/
🔗 Source: https://pubmed.ncbi.nlm.nih.gov/42107704/
Horizontal Gene Transfer: Latest results from PubMed
A fusion protein of polyphosphate kinase 1 (PPK1) and a Nudix hydrolase is involved in inorganic polyphosphate accumulation in the unicellular red alga Cyanidioschyzon merolae
#NCBI #PubMed #HGT
A fusion protein of polyphosphate kinase 1 (PPK1) and a Nudix hydrolase is involved in inorganic polyphosphate accumulation in the unicellular red alga Cyanidioschyzon merolae
#NCBI #PubMed #HGT
A fusion protein of polyphosphate kinase 1 (PPK1) and a Nudix hydrolase is involved in inorganic polyphosphate accumulation in the unicellular red alga Cyanidioschyzon merolae - PubMed
Inorganic polyphosphate (polyP) is a linear polymer of phosphate that plays various roles in cells, including in phosphate and metal homeostasis. Homologs of the vacuolar transporter chaperone 4 (VTC4), catalyzing polyP synthesis in many eukaryotes, are absent in red algae, which are among the earli …
pubmed.ncbi.nlm.nih.gov
December 19, 2024 at 5:30 PM
Horizontal Gene Transfer: Latest results from PubMed
A fusion protein of polyphosphate kinase 1 (PPK1) and a Nudix hydrolase is involved in inorganic polyphosphate accumulation in the unicellular red alga Cyanidioschyzon merolae
#NCBI #PubMed #HGT
A fusion protein of polyphosphate kinase 1 (PPK1) and a Nudix hydrolase is involved in inorganic polyphosphate accumulation in the unicellular red alga Cyanidioschyzon merolae
#NCBI #PubMed #HGT
Structural proteomics reveals the functional docking interface of ferredoxin-NADP+ reductase on photosystem I in the red alga Cyanidioschyzon merolae pubmed.ncbi.nlm.nih.gov/42385788/
July 2, 2026 at 7:16 AM
Structural proteomics reveals the functional docking interface of ferredoxin-NADP+ reductase on photosystem I in the red alga Cyanidioschyzon merolae pubmed.ncbi.nlm.nih.gov/42385788/
Systematic evaluation of Cyanidioschyzon merolae across photobioreactor systems: Linking reactor design to biomass production and biochemical composition https://www.biorxiv.org/content/10.64898/2026.06.17.732901v1
June 18, 2026 at 4:18 AM
Systematic evaluation of Cyanidioschyzon merolae across photobioreactor systems: Linking reactor design to biomass production and biochemical composition https://www.biorxiv.org/content/10.64898/2026.06.17.732901v1
Simple prerequisite of presequence for mitochondrial protein import in the unicellular red alga Cyanidioschyzon merolae https://www.biorxiv.org/content/10.1101/2024.02.19.581091v1
Simple prerequisite of presequence for mitochondrial protein import in the unicellular red alga Cyanidioschyzon merolae https://www.biorxiv.org/content/10.1101/2024.02.19.581091v1
Mitochondrial biogenesis relies on hundreds of proteins which are derived from genes encoded in the
www.biorxiv.org
February 21, 2024 at 8:31 AM
Simple prerequisite of presequence for mitochondrial protein import in the unicellular red alga Cyanidioschyzon merolae https://www.biorxiv.org/content/10.1101/2024.02.19.581091v1
A rapid CAT transformation protocol and nuclear transgene expression tools for metabolic engineering in Cyanidioschyzon merolae 10D https://www.biorxiv.org/content/10.1101/2024.07.30.605877v1
A rapid CAT transformation protocol and nuclear transgene expression tools for metabolic engineering in Cyanidioschyzon merolae 10D https://www.biorxiv.org/content/10.1101/2024.07.30.605877v1
The eukaryotic red alga Cyanidioschyzon merolae 10D is an emerging algal host for synthetic biology
www.biorxiv.org
July 31, 2024 at 1:46 PM
A rapid CAT transformation protocol and nuclear transgene expression tools for metabolic engineering in Cyanidioschyzon merolae 10D https://www.biorxiv.org/content/10.1101/2024.07.30.605877v1