New paper from our lab!
Happy to contribute to this collective effort, advancing our understanding of DDX3X and its role in #DDX3Xsyndrome
Happy to contribute to this collective effort, advancing our understanding of DDX3X and its role in #DDX3Xsyndrome
🧪 New paper alert!
In new work led by Adele Mossa out now in @natcomms.nature.com, we find that the #autism risk gene #DDX3X is a critical regulator of sexual dimorphisms in neuronal neurodevelopment 🧬 🧠
www.nature.com/articles/s41...
In new work led by Adele Mossa out now in @natcomms.nature.com, we find that the #autism risk gene #DDX3X is a critical regulator of sexual dimorphisms in neuronal neurodevelopment 🧬 🧠
www.nature.com/articles/s41...
Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X - Nature Communications
Genetic mutations in the DDX3X gene are associated with a neurodevelopmental disorder primarily affecting females. Here authors show that Ddx3x mediates sexual dimorphisms during brain development at ...
www.nature.com
May 20, 2025 at 1:54 PM
New paper from our lab!
Happy to contribute to this collective effort, advancing our understanding of DDX3X and its role in #DDX3Xsyndrome
Happy to contribute to this collective effort, advancing our understanding of DDX3X and its role in #DDX3Xsyndrome
Abigail Poff, Nicole Moss & @debbysilver.bsky.social generated a #MouseModel of the #DDX3XSyndrome and demonstrated that missense and loss-of-function variants have similar effects on #corticogenesis but act through distinct molecular targets.
#RareDisease
Read doi.org/10.1242/dmm....
#RareDisease
Read doi.org/10.1242/dmm....
January 6, 2026 at 12:01 PM
Abigail Poff, Nicole Moss & @debbysilver.bsky.social generated a #MouseModel of the #DDX3XSyndrome and demonstrated that missense and loss-of-function variants have similar effects on #corticogenesis but act through distinct molecular targets.
#RareDisease
Read doi.org/10.1242/dmm....
#RareDisease
Read doi.org/10.1242/dmm....
Encuentro de familias 2025, Oropesa del mar.
Un fin de semana maravilloso lleno de emociones, risas, y amor ❤️
Hasta el año que viene.
#DDX3Xsyndrome #sindromeDDX3X #enfermedadesraras #empezamosinvestigacion #biologosalpoder #ddx3x #ddx3syndrome #ddx3xsindrome #ddx3x
Un fin de semana maravilloso lleno de emociones, risas, y amor ❤️
Hasta el año que viene.
#DDX3Xsyndrome #sindromeDDX3X #enfermedadesraras #empezamosinvestigacion #biologosalpoder #ddx3x #ddx3syndrome #ddx3xsindrome #ddx3x
May 28, 2025 at 4:12 PM
Encuentro de familias 2025, Oropesa del mar.
Un fin de semana maravilloso lleno de emociones, risas, y amor ❤️
Hasta el año que viene.
#DDX3Xsyndrome #sindromeDDX3X #enfermedadesraras #empezamosinvestigacion #biologosalpoder #ddx3x #ddx3syndrome #ddx3xsindrome #ddx3x
Un fin de semana maravilloso lleno de emociones, risas, y amor ❤️
Hasta el año que viene.
#DDX3Xsyndrome #sindromeDDX3X #enfermedadesraras #empezamosinvestigacion #biologosalpoder #ddx3x #ddx3syndrome #ddx3xsindrome #ddx3x
#DDX3Xsyndrome A genetic neurodevelopmental disorder due to human #DDX3X mutations
In our preprint, we reveal highly pathogenic DDX3X syndrome mutations driving the assembly of persistent, solid-like DDX3X-condensates promoting neuronal death and A-beta aggregation.
www.biorxiv.org/content/10.6...
In our preprint, we reveal highly pathogenic DDX3X syndrome mutations driving the assembly of persistent, solid-like DDX3X-condensates promoting neuronal death and A-beta aggregation.
www.biorxiv.org/content/10.6...
February 3, 2026 at 4:17 AM
#DDX3Xsyndrome A genetic neurodevelopmental disorder due to human #DDX3X mutations
In our preprint, we reveal highly pathogenic DDX3X syndrome mutations driving the assembly of persistent, solid-like DDX3X-condensates promoting neuronal death and A-beta aggregation.
www.biorxiv.org/content/10.6...
In our preprint, we reveal highly pathogenic DDX3X syndrome mutations driving the assembly of persistent, solid-like DDX3X-condensates promoting neuronal death and A-beta aggregation.
www.biorxiv.org/content/10.6...