#DNAloopextrusion
⭐NAR Breakthrough!⭐
Bonato et al. propose a model for how the yeast #condensin SMC complex drives persistent #DNAloopextrusion, using #atomicforcemicroscopy and #moleculardynamics.

Read the full article here: doi.org/10.1093/nar/...
#NARBreakthrough #SMC #biophysics #genomefolding #yeast
Spontaneously directed loop extrusion in SMC complexes emerges from broken detailed balance and anisotropic DNA search
Abstract. DNA loop formation by structural maintenance of chromosome (SMC) proteins, including cohesin, condensin, and the SMC5/6 complex, plays a pivotal
doi.org
August 1, 2025 at 7:07 AM