excellent dname alert @jtwashin.bsky.social
February 13, 2026 at 8:20 PM
excellent dname alert @jtwashin.bsky.social
Strongly recommend DNAme researchers to take a look at this important study. Consistent with work from Schubeler lab: higher-order mut in DNAme reader proteins lead to only minor transcriptional changes. Reinforces the idea that DNAme does not establish heterochromatin through reader proteins
After a year of extra work and edits with @joncahn.bsky.social, I am overjoyed to share the final version of our work:
Characterization of DNA methylation reader proteins of Arabidopsis thaliana
Published in Genome Research @genomeresearch.bsky.social
genome.cshlp.org/content/earl...
Characterization of DNA methylation reader proteins of Arabidopsis thaliana
Published in Genome Research @genomeresearch.bsky.social
genome.cshlp.org/content/earl...
Characterization of DNA methylation reader proteins of Arabidopsis thaliana
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
genome.cshlp.org
December 9, 2024 at 8:28 AM
Strongly recommend DNAme researchers to take a look at this important study. Consistent with work from Schubeler lab: higher-order mut in DNAme reader proteins lead to only minor transcriptional changes. Reinforces the idea that DNAme does not establish heterochromatin through reader proteins
you weren't kidding with your dname
February 17, 2026 at 11:15 PM
you weren't kidding with your dname
demonstrating they understood the assignment in one extremely stupid dname
March 1, 2025 at 1:59 AM
demonstrating they understood the assignment in one extremely stupid dname
oh no spooky dname
October 30, 2025 at 10:58 PM
oh no spooky dname
Fun week for DNA methylation research! Here is a thread of three cool papers that came out, all with an evolution angle. And a bonus 4th that examines DNAme/PcG interplay (certainly an interest for our lab!) #Epigenetics
November 19, 2025 at 9:48 AM
Fun week for DNA methylation research! Here is a thread of three cool papers that came out, all with an evolution angle. And a bonus 4th that examines DNAme/PcG interplay (certainly an interest for our lab!) #Epigenetics
speaking of which your spooky dname this year should be dragon moll Z
August 17, 2025 at 12:50 AM
speaking of which your spooky dname this year should be dragon moll Z
New dname: "the female John wick"
June 26, 2025 at 4:44 AM
New dname: "the female John wick"
ok but that is a good dname
September 19, 2025 at 9:15 PM
ok but that is a good dname
i like the new dname
December 10, 2025 at 6:39 PM
i like the new dname
*looks at katie's dname* oh no
July 15, 2023 at 9:48 PM
*looks at katie's dname* oh no
lol your dname. i'm honored. @jerrified.bsky.social check this out
August 7, 2026 at 12:35 AM
lol your dname. i'm honored. @jerrified.bsky.social check this out
Wow, big time preprint drop from @jacobsenucla.bsky.social lab! One of the holy grails of DNA methylation research. Also, the 2-figure paper reminds me of the classic Science Brevia from Simon Chan and Steve showing RNA-directed DNA methylation drives de novo DNAme www.biorxiv.org/content/10.6...
www.biorxiv.org
February 16, 2026 at 3:05 PM
Wow, big time preprint drop from @jacobsenucla.bsky.social lab! One of the holy grails of DNA methylation research. Also, the 2-figure paper reminds me of the classic Science Brevia from Simon Chan and Steve showing RNA-directed DNA methylation drives de novo DNAme www.biorxiv.org/content/10.6...
#1 Centromeres are epigenetic loci defined by CENP-A, positioned in unmethylated DNA flanked by highly methylated regions. Our work, published in @natgenet.nature.com in collaboration with @naltemose.bsky.social investigates the role of DNAme at human centromeres www.nature.com/articles/s41...
DNA methylation influences human centromere positioning and function - Nature Genetics
Genome-wide and targeted perturbation of DNA methylation at centromeres affects CENP-A positioning and centromere structure, resulting in aneuploidy and reduced cell viability.
www.nature.com
September 4, 2025 at 1:10 PM
#1 Centromeres are epigenetic loci defined by CENP-A, positioned in unmethylated DNA flanked by highly methylated regions. Our work, published in @natgenet.nature.com in collaboration with @naltemose.bsky.social investigates the role of DNAme at human centromeres www.nature.com/articles/s41...
Nice example of epigenetic memory of "active" chromatin, or put differently "anti-silencing". Akin to Dppa2/4-mediated K4me3 in mammals: protects against DNAme/silencing of developmental genes that need to be turned on at some point (from @jamiehackett.bsky.social and @meleckmas.bsky.social labs)
✨ Excited to share my latest preprint on how H3K4 methylation promotes transcriptional memory from gametes to embryos across a transcriptionally silent window — crucial for proper zygotic genome activation and development. 🐸🧬✨
📄 Check it out here: doi.org/10.1101/2025...
👇 Highlights below
📄 Check it out here: doi.org/10.1101/2025...
👇 Highlights below
H3K4 methylation-promoted transcriptional memory ensures faithful zygotic genome activation and embryonic development
In the life of a vertebrate embryo, gene expression is initiated for the first time at zygotic genome activation (ZGA). Maternally expressed transcription factors present in the embryo are essential f...
doi.org
January 22, 2025 at 2:31 PM
Nice example of epigenetic memory of "active" chromatin, or put differently "anti-silencing". Akin to Dppa2/4-mediated K4me3 in mammals: protects against DNAme/silencing of developmental genes that need to be turned on at some point (from @jamiehackett.bsky.social and @meleckmas.bsky.social labs)
Dname checks out
September 16, 2026 at 6:48 PM
Dname checks out
haha i just noticed the dname. blasphemous (it's august) but nice
August 24, 2025 at 1:05 AM
haha i just noticed the dname. blasphemous (it's august) but nice
love the new dname
September 2, 2024 at 6:49 PM
love the new dname
What a great weekend listen, with everything that I like! From arabidopsis to mouse DNAme and a touch of Polycomb.
Btw as a member of the Steve Jacobsen fan club I'd definitely listen to that!
Btw as a member of the Steve Jacobsen fan club I'd definitely listen to that!
In this episode of the Epigenetics Podcast, we talked with @maxvcg.bsky.social from the @ijmonod.bsky.social about his work on epigenetic consequences of DNA methylation in development. #podcast #chromatin #epigenetics
Listen here: https://buff.ly/3ZXWGuy
Listen here: https://buff.ly/3ZXWGuy
December 21, 2024 at 9:13 AM
What a great weekend listen, with everything that I like! From arabidopsis to mouse DNAme and a touch of Polycomb.
Btw as a member of the Steve Jacobsen fan club I'd definitely listen to that!
Btw as a member of the Steve Jacobsen fan club I'd definitely listen to that!
Looking forward to kicking off the school year with a talk from @cwhanna.bsky.social @loke-ctr.bsky.social @uniofcam.bsky.social. One of the few people I would rank alongside my old boss (@deborahbourchis.bsky.social) for expertise in mammalian DNAme. Should be a good one! @ijmonod.bsky.social
July 15, 2025 at 4:17 PM
Looking forward to kicking off the school year with a talk from @cwhanna.bsky.social @loke-ctr.bsky.social @uniofcam.bsky.social. One of the few people I would rank alongside my old boss (@deborahbourchis.bsky.social) for expertise in mammalian DNAme. Should be a good one! @ijmonod.bsky.social
New on tweets-2-bsky! Auto-sync Twitter profiles! mirroring new accounts is now easier, it auto-fetches the profile picture, banner, dname + bio of the profile, so you don't have to manually set it anymore!
update to latest (however you installed)!
an e.g.: @wbtourupdates.bsky.social
update to latest (however you installed)!
an e.g.: @wbtourupdates.bsky.social
GitHub - j4ckxyz/tweets-2-bsky
Contribute to j4ckxyz/tweets-2-bsky development by creating an account on GitHub.
github.com
February 21, 2026 at 9:36 PM
New on tweets-2-bsky! Auto-sync Twitter profiles! mirroring new accounts is now easier, it auto-fetches the profile picture, banner, dname + bio of the profile, so you don't have to manually set it anymore!
update to latest (however you installed)!
an e.g.: @wbtourupdates.bsky.social
update to latest (however you installed)!
an e.g.: @wbtourupdates.bsky.social
oh god what's this new dname
April 29, 2025 at 1:40 AM
oh god what's this new dname
sometimes i wanna repost someone but their dname is like annular eclussy
October 16, 2023 at 6:20 PM
sometimes i wanna repost someone but their dname is like annular eclussy
☀️ SPECIAL ISSUE RESEARCH 🌡️
📖 Garro et al. show that non-CG DNA methylation represses SDC expression to regulate auxin & gibberellin-related genes, maintaining hypocotyl elongation in warm temps.
🔗 doi.org/10.1093/jxb/...
@maigarro.bsky.social @maticapella.bsky.social
#PlantScience 🧪
📖 Garro et al. show that non-CG DNA methylation represses SDC expression to regulate auxin & gibberellin-related genes, maintaining hypocotyl elongation in warm temps.
🔗 doi.org/10.1093/jxb/...
@maigarro.bsky.social @maticapella.bsky.social
#PlantScience 🧪
July 1, 2025 at 3:11 PM
☀️ SPECIAL ISSUE RESEARCH 🌡️
📖 Garro et al. show that non-CG DNA methylation represses SDC expression to regulate auxin & gibberellin-related genes, maintaining hypocotyl elongation in warm temps.
🔗 doi.org/10.1093/jxb/...
@maigarro.bsky.social @maticapella.bsky.social
#PlantScience 🧪
📖 Garro et al. show that non-CG DNA methylation represses SDC expression to regulate auxin & gibberellin-related genes, maintaining hypocotyl elongation in warm temps.
🔗 doi.org/10.1093/jxb/...
@maigarro.bsky.social @maticapella.bsky.social
#PlantScience 🧪
dang dude, hope the pain isn't bad.
new dname opportunity though: Biking Considered Harmful
new dname opportunity though: Biking Considered Harmful
October 31, 2023 at 2:20 PM
dang dude, hope the pain isn't bad.
new dname opportunity though: Biking Considered Harmful
new dname opportunity though: Biking Considered Harmful