#ECOFF
👀 Listening to EUCAST review by Dr. Muller… Reproducibility of MIC values is very important if you want to set a breakpoint…. Discussing ECOFF vs breakpoints… I must confess the whole ECOFF discussion is still a topic that can leave me scratching my head 🫣 #ESCMID2025 #ESCMIDglobal #IDsky
April 12, 2025 at 7:05 AM
EUCAST have determined the ECOFF for penicillin in GBS to be 0.125 mg/L. Isolates with MICs above this threshold are considered to have acquired resistance mechanisms. There is growing international literature reporting the isolation of clinical GBS strains that have MICs above the ECOFF #idsky
In general, group B streptococci (GBS; Streptococcus agalactiae) are considered universally susceptible to penicillin
🆕️✨️The first report of a penicillin-resistant group B Streptococcus(MIC = 1 mg/L) isolated from a patient with pji the UK #idsky
academic.oup.com/jac/advance-...
A case of penicillin-resistant group B Streptococcus isolated from a patient in the UK
AbstractObjectives. In England, group B streptococci (GBS; Streptococcus agalactiae) are considered universally susceptible to penicillin. Reports from Afr
academic.oup.com
November 16, 2024 at 11:05 AM
EUCAST update session at #escmidglobal

You'll be glad to hear that our Antimicrobial Susceptibility Testing mini-series... Was correct!

Some extra insights today:
1. Need 3 MIC distributions to set a (T)ECOFF and 5 to set an ECOFF. 2. ECOFF does not always correlate to breakpoints.
April 12, 2025 at 9:22 AM
Honestly I enjoy just browsing EUCAST's ECOFF database. 😆
November 15, 2024 at 4:00 AM
I'm currently working on my next video about my recent Passover trip to go metal-detecting on the land my Ecoff ancestors owned in Alliance, NJ.
November 13, 2024 at 9:13 PM
Over 250 votes cast so far this morning at Ecoff Elementary, also in HD 75, said the chief officers of election.

@vcucns.bsky.social
November 4, 2025 at 1:38 PM
ah zut, c'etait ecoff j'ai changé le handle
C'est fait
April 19, 2026 at 5:27 PM
Tout ça se résume en : le traumatisme c'est pas les 260 000 morts + 250 000 covid long.
Il y a eu des conséquences sociales, notamment les ado de l'époque et les violences familiales, mais comme ecoff les "hommages" me laissent un gout bien amère, comme si on avait exagéré sans raison...
Je lis les commentaires sur "l'anniversaire" du confinement de gens dont le plus gros traumatisme aura donc été de ne plus pouvoir aller en terrasse. D'articles expliquant que les personnes âgées soufflant de troubles cognitifs et ne sortant pas de chez elles ont vu leur troubles cognitifs
March 17, 2025 at 8:56 AM
There’s no direct ECOFF on EUCAST for oritavancin for E. faecium, however out of 320 observations, 41 had an MIC of 0.125 and only 8 were above that MIC. I’d say it’s on the higher end of comfort, but no great data for clinical outcomes.
December 31, 2024 at 9:00 PM
In my talk about Jewish Genetic #Genealogy, I use my Kaseno/Khazanovich family as an example of how to identify a significant #DNA match under 200cM. What better further proof than finding family photos with two branches of the family? One photo is from my collection, the other from my Kahn cousins.
December 9, 2024 at 9:48 PM
Ran into Dougherty again at Ecoff Elementary!

She said no matter the outcome of the election, it’s important to stay engaged and hold representatives accountable.

@vcucns.bsky.social
November 4, 2025 at 2:27 PM
🌏 In our My Week As… series, Elise Ecoff, chief education officer at international schools group Nord Anglia, talks about her role in developing the 'four pillars' of strategy: academic outcomes, wellbeing, creativity and global connectedness
My Week As... Nord Anglia chief education officer
In our ‘My Week As’ series, a senior sector leader reveals what a typical week looks like in their role. Here, we talk to Elise Ecoff of Nord Anglia
www.tes.com
March 17, 2025 at 7:05 AM
How Pittsburgh's plastic bag ban changed shopping habits
How Pittsburgh's plastic bag ban changed shopping habits
For almost two years now, there’s always an item Rachel Ecoff, of East Liberty, brings with her when she goes shopping. Her own tote bag. That’s...
www.post-gazette.com
July 19, 2025 at 9:00 AM
🦠 New EUCAST breakpoints for Candida auris (Candidozyma auris)! Learn how to interpret MICs for amphotericin B, echinocandins & flucytosine based on robust multicenter data. A must-read for clinical labs.
🔗 pubmed.ncbi.nlm.nih.gov/40651666/
#CandidaAuris #EUCAST #AntifungalResistance
How to interpret MICs of amphotericin B, echinocandins and flucytosine against Candida auris (Candidozyma auris) according to the newly established European Committee for Antimicrobial Susceptibility ...
The following ECOFFs and breakpoints were established for C auris: amphotericin B: ECOFF: 2 mg/L, S: ≤0.001 mg/L, R: >2 mg/L; implying that the entire wild-type distribution is susceptible, increased ...
pubmed.ncbi.nlm.nih.gov
August 4, 2025 at 7:33 AM
Amikacin breakpoints were lowered down to /32 mg/L R ➡️ largely based on USCAST PK/PD modeling and ECOFF Finder demonstrating ECV of 8 mg/L, which agrees with EUCAST. **Based on dosing of 20 mg/kg**
📌See pubmed.ncbi.nlm.nih.gov/36946729/
June 3, 2025 at 1:40 PM
Hey #RVA! There is a firehouse primary THIS SUNDAY from 10AM-6PM to fill Senator Hashmi’s seat (SD 15).

Polling locations will be Thomas Dale High School, Manchester Middle School, and Hickory Hill Recreation Center.

SPREAD THE WORD!
December 4, 2025 at 4:50 PM
Establishing the Epidemiological Cut-Off Value (ECOFF) for Cefquinome Against Staphylococcus aureus Using Standardised MIC Data
Establishing the Epidemiological Cut-Off Value (ECOFF) for Cefquinome Against Staphylococcus aureus Using Standardised MIC Data - PubMed
Staphylococcus aureus is a major pathogen responsible for a wide range of infections in both animals and humans, and the increasing emergence of antimicrobial resistance highlights the need for effective...
t.co
June 19, 2026 at 6:42 PM