WEED EPISODE:
endocannabinoids
CBD, CBN, CBG, THCV
gummies
dad grass
indica vs. sativa
the justice system
addiction, the munchies + more.
Cannabinologists Dr. @zivacooper.bsky.social + @smithcollege.bsky.social anthro Dr. Melly -- divulge all.
Also, secrets.
www.alieward.com/ologies/cann...
endocannabinoids
CBD, CBN, CBG, THCV
gummies
dad grass
indica vs. sativa
the justice system
addiction, the munchies + more.
Cannabinologists Dr. @zivacooper.bsky.social + @smithcollege.bsky.social anthro Dr. Melly -- divulge all.
Also, secrets.
www.alieward.com/ologies/cann...
www.alieward.com
April 9, 2026 at 7:33 AM
WEED EPISODE:
endocannabinoids
CBD, CBN, CBG, THCV
gummies
dad grass
indica vs. sativa
the justice system
addiction, the munchies + more.
Cannabinologists Dr. @zivacooper.bsky.social + @smithcollege.bsky.social anthro Dr. Melly -- divulge all.
Also, secrets.
www.alieward.com/ologies/cann...
endocannabinoids
CBD, CBN, CBG, THCV
gummies
dad grass
indica vs. sativa
the justice system
addiction, the munchies + more.
Cannabinologists Dr. @zivacooper.bsky.social + @smithcollege.bsky.social anthro Dr. Melly -- divulge all.
Also, secrets.
www.alieward.com/ologies/cann...
Check out our latest paper:
The Contribution of endocannabinoids to placebo analgesia
www.biorxiv.org/content/10.6...
This is an ongoing collaboration with David Finn & @laurenatlas.bsky.social
Take away: beta-endorphins gate the contributions of endocannabinoids to placebo analgesia.
The Contribution of endocannabinoids to placebo analgesia
www.biorxiv.org/content/10.6...
This is an ongoing collaboration with David Finn & @laurenatlas.bsky.social
Take away: beta-endorphins gate the contributions of endocannabinoids to placebo analgesia.
www.biorxiv.org
February 27, 2026 at 8:38 AM
Check out our latest paper:
The Contribution of endocannabinoids to placebo analgesia
www.biorxiv.org/content/10.6...
This is an ongoing collaboration with David Finn & @laurenatlas.bsky.social
Take away: beta-endorphins gate the contributions of endocannabinoids to placebo analgesia.
The Contribution of endocannabinoids to placebo analgesia
www.biorxiv.org/content/10.6...
This is an ongoing collaboration with David Finn & @laurenatlas.bsky.social
Take away: beta-endorphins gate the contributions of endocannabinoids to placebo analgesia.
Nature research paper: Endocannabinoids facilitate reward engagement through retrograde gain control
go.nature.com/4iwvL2x
go.nature.com/4iwvL2x
Endocannabinoids facilitate reward engagement through retrograde gain control - Nature
A key role for retrograde neuromodulatory signalling in motivated behaviour is shown through dynamic endocannabinoid release within a thalamostriatal circuit that regulates behavioural engagement during reward seeking.
go.nature.com
August 28, 2026 at 8:35 AM
Nature research paper: Endocannabinoids facilitate reward engagement through retrograde gain control
go.nature.com/4iwvL2x
go.nature.com/4iwvL2x
endocannabinoids i need you
October 12, 2025 at 11:07 AM
endocannabinoids i need you
Hey #acnp2024 come join @mayoonthebrain.bsky.social and I on Sun at 3 pm for our panel on endocannabinoids as a target for stress related psychiatric disorders. Also features Sachin Patel as well as really cool human work from Sara Kroll! #cannabinerds I’m #Team2-AG 😁
December 7, 2024 at 8:42 PM
Hey #acnp2024 come join @mayoonthebrain.bsky.social and I on Sun at 3 pm for our panel on endocannabinoids as a target for stress related psychiatric disorders. Also features Sachin Patel as well as really cool human work from Sara Kroll! #cannabinerds I’m #Team2-AG 😁
A new collaborative paper with Ralf Brandes lab @ Goethe University Frankfurt: endocannabinoids as ligands for NR4A (Nurr1 and Nur77) #nuclearreceptors! doi.org/10.1111/bph....
BPS Publications
Background and purpose Endocannabinoids are lipid mediators, which elicit complex biological effects that extend beyond the central nervous system. Tissue concentrations of endocannabinoids increase...
doi.org
November 21, 2024 at 5:02 AM
A new collaborative paper with Ralf Brandes lab @ Goethe University Frankfurt: endocannabinoids as ligands for NR4A (Nurr1 and Nur77) #nuclearreceptors! doi.org/10.1111/bph....
Have a great weekend everyone, especially those around the world fighting to legalise cannabis
Our bodies naturally make endocannabinoids - cannabis is medicine, not a drug.
🐝
Our bodies naturally make endocannabinoids - cannabis is medicine, not a drug.
🐝
August 29, 2025 at 8:24 AM
Have a great weekend everyone, especially those around the world fighting to legalise cannabis
Our bodies naturally make endocannabinoids - cannabis is medicine, not a drug.
🐝
Our bodies naturally make endocannabinoids - cannabis is medicine, not a drug.
🐝
Hey, 🇨🇦 neuroscientist who studies stress, endocannabinoids and cannabis and an OG #cannabinerd. This is my 16th straight ACNP meeting and I am also a reviewing editor for @npp-journal.bsky.social and will be at the meet the editors session on Monday. #ACNP2024
December 7, 2024 at 11:03 PM
Hey, 🇨🇦 neuroscientist who studies stress, endocannabinoids and cannabis and an OG #cannabinerd. This is my 16th straight ACNP meeting and I am also a reviewing editor for @npp-journal.bsky.social and will be at the meet the editors session on Monday. #ACNP2024
Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus - Nature Neuroscience
Distinct endocannabinoids signal to either astrocytes or neurons, evoking contrasting regulation of synaptic function. This works reveals the high degree of complexity of neuronal and astrocytic signa...
www.nature.com
January 1, 2026 at 7:46 PM
Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus
www.nature.com/articles/s41...
www.nature.com/articles/s41...
I've noticed the first ~25 min of my hour runs are the hardest, then the adrenaline/endorphins/endocannabinoids take over
I have crafted the perfect solution, then I'll just switch to Blind Guardian or w/e
I have crafted the perfect solution, then I'll just switch to Blind Guardian or w/e
December 6, 2025 at 2:59 AM
I've noticed the first ~25 min of my hour runs are the hardest, then the adrenaline/endorphins/endocannabinoids take over
I have crafted the perfect solution, then I'll just switch to Blind Guardian or w/e
I have crafted the perfect solution, then I'll just switch to Blind Guardian or w/e
incidentally, APAP has several extremely unusual effects for any medication on account of it acts similar to a SSRI or SNRI but for endocannabinoids. people dosed with tylenol experience reduced symptoms of religious awe. anecdotally i tend to take it as a rescue for religious psychosis
September 22, 2025 at 10:58 PM
incidentally, APAP has several extremely unusual effects for any medication on account of it acts similar to a SSRI or SNRI but for endocannabinoids. people dosed with tylenol experience reduced symptoms of religious awe. anecdotally i tend to take it as a rescue for religious psychosis
🚨 New paper in @npp-journal.bsky.social! We combined data from 3 studies (including an SSRI RCT) to explore how endocannabinoids relate to anxiety & treatment response in kids + teens. Team science w/ Jeanne Barcelona, Jeffrey Strawn & more!
www.nature.com/articles/s41...
@wsuthinklab.bsky.social
www.nature.com/articles/s41...
@wsuthinklab.bsky.social
Circulating endocannabinoids in children and adolescents: associations with anxiety and the impact of selective serotonin reuptake inhibitors - Neuropsychopharmacology
Neuropsychopharmacology - Circulating endocannabinoids in children and adolescents: associations with anxiety and the impact of selective serotonin reuptake inhibitors
www.nature.com
June 30, 2025 at 4:50 PM
🚨 New paper in @npp-journal.bsky.social! We combined data from 3 studies (including an SSRI RCT) to explore how endocannabinoids relate to anxiety & treatment response in kids + teens. Team science w/ Jeanne Barcelona, Jeffrey Strawn & more!
www.nature.com/articles/s41...
@wsuthinklab.bsky.social
www.nature.com/articles/s41...
@wsuthinklab.bsky.social
@lcornelas.bsky.social crushing her talk at the 25th National Science Network on Drug Abuse conference at @universityofmiami.bsky.social! Incredible and important work on #GABA, #endocannabinoids, traumatic #stress, and #alcohol use in animal models.
#NSNDA2025 #addictionscience #trauma @unm.edu
#NSNDA2025 #addictionscience #trauma @unm.edu
October 24, 2025 at 1:53 PM
@lcornelas.bsky.social crushing her talk at the 25th National Science Network on Drug Abuse conference at @universityofmiami.bsky.social! Incredible and important work on #GABA, #endocannabinoids, traumatic #stress, and #alcohol use in animal models.
#NSNDA2025 #addictionscience #trauma @unm.edu
#NSNDA2025 #addictionscience #trauma @unm.edu
Did you know some people have a naturally upregulated ECS (Endocannabinoid System)? They overproduce endocannabinoids, and THC use balances them. 10% of ppl can burn all day w/ no Tolerance issues, But, most are downregulated & need CBGa:CBDa for Balance (Blueberry Cupcake by Mass Yield Cultivation)
May 7, 2025 at 6:28 PM
Did you know some people have a naturally upregulated ECS (Endocannabinoid System)? They overproduce endocannabinoids, and THC use balances them. 10% of ppl can burn all day w/ no Tolerance issues, But, most are downregulated & need CBGa:CBDa for Balance (Blueberry Cupcake by Mass Yield Cultivation)
Exciting research on how to preserve endocannabinoids in human donor breast milk: "The human milk endocannabinoidome is preserved by high hydrostatic pressure processing but altered by holder pasteurization" Published March 11, 2025: #BabiesDrinkCannabinoids #Cannabis #Weed #EndoCannabinoids #ECS
March 31, 2025 at 1:55 PM
Exciting research on how to preserve endocannabinoids in human donor breast milk: "The human milk endocannabinoidome is preserved by high hydrostatic pressure processing but altered by holder pasteurization" Published March 11, 2025: #BabiesDrinkCannabinoids #Cannabis #Weed #EndoCannabinoids #ECS
The Real Story Behind "Reproduction, Embryogenesis, and Development" focuses on CB1 and CB2 and other receptors and endocannabinoids.
wmhfarms.com/more-than-a-...
wmhfarms.com/more-than-a-...
April 24, 2025 at 9:45 AM
The Real Story Behind "Reproduction, Embryogenesis, and Development" focuses on CB1 and CB2 and other receptors and endocannabinoids.
wmhfarms.com/more-than-a-...
wmhfarms.com/more-than-a-...
May 9 Masturbation Fact: (Part 1) Can orgasms reduce pain? Endorphins are the bodies natural painkiller, & endocannabinoids reduce inflammation - both are released in the body when experiencing sexual pleasure. Studies have shown a link between masturbation & reduced pain from headaches & migraines.
May 9, 2024 at 4:26 AM
May 9 Masturbation Fact: (Part 1) Can orgasms reduce pain? Endorphins are the bodies natural painkiller, & endocannabinoids reduce inflammation - both are released in the body when experiencing sexual pleasure. Studies have shown a link between masturbation & reduced pain from headaches & migraines.
"Association of Endocannabinoids with Pain in Endometriosis" (2022) found that women with endometriosis experience significant fluctuations in endocannabinoid levels, particularly anandamide (AEA) and 2-arachidonoylglycerol (2-AG). By modulating the levels, #CBD and #CBG can provide relief #Cannabis
March 8, 2025 at 3:18 PM
"Association of Endocannabinoids with Pain in Endometriosis" (2022) found that women with endometriosis experience significant fluctuations in endocannabinoid levels, particularly anandamide (AEA) and 2-arachidonoylglycerol (2-AG). By modulating the levels, #CBD and #CBG can provide relief #Cannabis
Happy to share my postdoc paper with @joeycheers.bsky.social & collaborators!
Building on the work of many former lab members, we describe a VP-VTA projection modulated by endocannabinoids that guides action selection informed by learned cues:
www.cell.com/cell-reports...
Building on the work of many former lab members, we describe a VP-VTA projection modulated by endocannabinoids that guides action selection informed by learned cues:
www.cell.com/cell-reports...
Midbrain endocannabinoids actuate dopamine-based action selection
Dopamine signals guide adaptive responses to reward- and threat-predictive cues, yet
the mechanisms shaping these rapid dynamics remain unclear. Luján et al. identify
midbrain endocannabinoid signalin...
www.cell.com
April 22, 2026 at 2:46 PM
Happy to share my postdoc paper with @joeycheers.bsky.social & collaborators!
Building on the work of many former lab members, we describe a VP-VTA projection modulated by endocannabinoids that guides action selection informed by learned cues:
www.cell.com/cell-reports...
Building on the work of many former lab members, we describe a VP-VTA projection modulated by endocannabinoids that guides action selection informed by learned cues:
www.cell.com/cell-reports...
Juoksueuforia (runner's high) ei olekaan endorfiineja vaan endokannabinoideja. Otollisin olosuhde synnylle on kun hölkkää 70 % sykkeellä 22 minuuttia.
www.psychologytoday.com/us/blog/the-...
www.psychologytoday.com/us/blog/the-...
“Runner’s High” Depends on Endocannabinoids (Not Endorphins)
Contrary to popular belief, a new study reaffirms that experiencing a so-called "runner's high" doesn't depend on endorphins—but does rely on exercise-induced endocannabinoids.
www.psychologytoday.com
September 23, 2025 at 12:40 PM
Juoksueuforia (runner's high) ei olekaan endorfiineja vaan endokannabinoideja. Otollisin olosuhde synnylle on kun hölkkää 70 % sykkeellä 22 minuuttia.
www.psychologytoday.com/us/blog/the-...
www.psychologytoday.com/us/blog/the-...
Your body naturally has receptors for it. Were you born to smoke cannabis? 😉🤔💚🥦🌱
#cannabis #endocannabinoids #medicine
#cannabis #endocannabinoids #medicine
August 14, 2026 at 1:40 AM
Your body naturally has receptors for it. Were you born to smoke cannabis? 😉🤔💚🥦🌱
#cannabis #endocannabinoids #medicine
#cannabis #endocannabinoids #medicine
Cannabis helps Huntington’s disease (HD) by supporting the Endocannabinoid System (ECS) which regulates movement, mood, and brain health. In HD, brain cells break down, causing motor and cognitive issues, #CBD and CBGa protect neurons, reduce inflammation, boosting natural endocannabinoids #Cannabis
April 8, 2025 at 12:35 PM
Cannabis helps Huntington’s disease (HD) by supporting the Endocannabinoid System (ECS) which regulates movement, mood, and brain health. In HD, brain cells break down, causing motor and cognitive issues, #CBD and CBGa protect neurons, reduce inflammation, boosting natural endocannabinoids #Cannabis
Coffee & Cannabis Time 💚
I start off my day with a walk, hemp extracts ingested, and 16 oz of very clean water. Hydration is so important for our Endocannabinoid System, without it we don't create new receptors or endocannabinoids - without fresh receptors you build a THC Tolerance ~ #Cannabis
I start off my day with a walk, hemp extracts ingested, and 16 oz of very clean water. Hydration is so important for our Endocannabinoid System, without it we don't create new receptors or endocannabinoids - without fresh receptors you build a THC Tolerance ~ #Cannabis
February 9, 2025 at 5:22 PM
Coffee & Cannabis Time 💚
I start off my day with a walk, hemp extracts ingested, and 16 oz of very clean water. Hydration is so important for our Endocannabinoid System, without it we don't create new receptors or endocannabinoids - without fresh receptors you build a THC Tolerance ~ #Cannabis
I start off my day with a walk, hemp extracts ingested, and 16 oz of very clean water. Hydration is so important for our Endocannabinoid System, without it we don't create new receptors or endocannabinoids - without fresh receptors you build a THC Tolerance ~ #Cannabis