Evidence for an active role of #EndothalialCell in #Aortopathy

EC TRPV4 activity⏫
🐭#AbdominalAorticAneurysm (local elastase)
via⏫EC #Apoptosis (how does this propagate to #SmoothMuscleCell loss) w/o altering #NitricOxide

#AortaEd
#EurJPharmacol 2024
www.sciencedirect.com/science/arti...

#research

Lipidized analogues of the anorexigenic CART (cocaine- and amphetamine-regulated transcript) neuropeptide show anorexigenic and neuroprotective potential in mouse model of monosodium-glutamate induced obesity (Pačesová) - #EurJPharmacol: doi.org/10.1016/j.ej...

@iocbprague.bsky.social