📝 Available online - the Review "The nuclear export receptor CRM1/XPO1 and its diverse cargoes" from Ralph Kehlenbach and @yuhminchook.bsky.social.
#CRM1 #Exportin1 #NuclearTransport #NuclearPoreComplex #RNAExport
Read it here: authors.elsevier.com/sd/article/S...
#CRM1 #Exportin1 #NuclearTransport #NuclearPoreComplex #RNAExport
Read it here: authors.elsevier.com/sd/article/S...
October 7, 2025 at 3:51 PM
📝 Available online - the Review "The nuclear export receptor CRM1/XPO1 and its diverse cargoes" from Ralph Kehlenbach and @yuhminchook.bsky.social.
#CRM1 #Exportin1 #NuclearTransport #NuclearPoreComplex #RNAExport
Read it here: authors.elsevier.com/sd/article/S...
#CRM1 #Exportin1 #NuclearTransport #NuclearPoreComplex #RNAExport
Read it here: authors.elsevier.com/sd/article/S...
Beautiful work! RRE binds CRM1. Wow! 😊
#HIV1 #Rev #RRE #CRM1 #Exportin1 #Ran
www.cell.com/molecular-ce...
#HIV1 #Rev #RRE #CRM1 #Exportin1 #Ran
www.cell.com/molecular-ce...
The HIV-1 nuclear export complex reveals the role of RNA in CRM1 cargo recognition
The HIV nuclear export complex shows that CRM1 recognizes diverse cargos through distinct
sites, utilizing multipartite recognition via the NES and additional protein and RNA
contacts. A unique CRM1 d...
www.cell.com
August 22, 2025 at 1:15 PM
Beautiful work! RRE binds CRM1. Wow! 😊
#HIV1 #Rev #RRE #CRM1 #Exportin1 #Ran
www.cell.com/molecular-ce...
#HIV1 #Rev #RRE #CRM1 #Exportin1 #Ran
www.cell.com/molecular-ce...
Cool! New role for #Exportin1 #Crm1 #Xpo1
#Adaptor #NuclearPore #NPC #TranscriptionFactor
Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex: Molecular Cell www.cell.com/molecular-ce...
#Adaptor #NuclearPore #NPC #TranscriptionFactor
Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex: Molecular Cell www.cell.com/molecular-ce...
Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex
Many genes physically interact with the nuclear pore complex (NPC), which requires
transcription factors (TFs). Ge et al. show that the exportin Crm1 binds TFs and nuclear
pore proteins to dock chroma...
www.cell.com
March 11, 2025 at 3:07 PM
Cool! New role for #Exportin1 #Crm1 #Xpo1
#Adaptor #NuclearPore #NPC #TranscriptionFactor
Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex: Molecular Cell www.cell.com/molecular-ce...
#Adaptor #NuclearPore #NPC #TranscriptionFactor
Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex: Molecular Cell www.cell.com/molecular-ce...
Co-targeting KRAS and Exportin1 as an effective therapeutic strategy for KRASG12D mutant pancreatic ductal adenocarcinoma https://www.biorxiv.org/content/10.1101/2025.11.21.689857v1
November 25, 2025 at 4:48 PM
Co-targeting KRAS and Exportin1 as an effective therapeutic strategy for KRASG12D mutant pancreatic ductal adenocarcinoma https://www.biorxiv.org/content/10.1101/2025.11.21.689857v1
Co-targeting KRAS and Exportin1 as an effective therapeutic strategy for KRASG12D mutant pancreatic ductal adenocarcinoma https://www.biorxiv.org/content/10.1101/2025.11.21.689857v1
November 25, 2025 at 4:48 PM
Co-targeting KRAS and Exportin1 as an effective therapeutic strategy for KRASG12D mutant pancreatic ductal adenocarcinoma https://www.biorxiv.org/content/10.1101/2025.11.21.689857v1
Co-targeting KRAS and Exportin1 as an effective therapeutic strategy for KRASG12D mutant pancreatic ductal adenocarcinoma 🧪 www.biorxiv.org/content/10.1...
Co-targeting KRAS and Exportin1 as an effective therapeutic strategy for KRASG12D mutant pancreatic ductal adenocarcinoma
Background Several KRASG12D inhibitors (KRASG12Di) are under clinical evaluation for pancreatic ductal adenocarcinoma (PDAC). However, as seen with other first generation KRAS inhibitors, resistance m...
www.biorxiv.org
November 28, 2025 at 8:32 PM
Co-targeting KRAS and Exportin1 as an effective therapeutic strategy for KRASG12D mutant pancreatic ductal adenocarcinoma 🧪 www.biorxiv.org/content/10.1...