New issue ONLINE!
✅ FFR-guided PCI of non-culprit lesions in NSTE-ACS;
✅ Radial wall strain and residual risk after PCI;
✅ Sex-based differences in antiplatelet therapy;
✅ Cardiogenic shock phenotyping after OHCA;
and more 👇
eurointervention.pcronline.com/issue/volume...
✅ FFR-guided PCI of non-culprit lesions in NSTE-ACS;
✅ Radial wall strain and residual risk after PCI;
✅ Sex-based differences in antiplatelet therapy;
✅ Cardiogenic shock phenotyping after OHCA;
and more 👇
eurointervention.pcronline.com/issue/volume...
September 25, 2026 at 3:34 PM
New issue ONLINE!
✅ FFR-guided PCI of non-culprit lesions in NSTE-ACS;
✅ Radial wall strain and residual risk after PCI;
✅ Sex-based differences in antiplatelet therapy;
✅ Cardiogenic shock phenotyping after OHCA;
and more 👇
eurointervention.pcronline.com/issue/volume...
✅ FFR-guided PCI of non-culprit lesions in NSTE-ACS;
✅ Radial wall strain and residual risk after PCI;
✅ Sex-based differences in antiplatelet therapy;
✅ Cardiogenic shock phenotyping after OHCA;
and more 👇
eurointervention.pcronline.com/issue/volume...
3 ways FFR-guided diagnosis is changing cardiology: (1) Reduces unnecessary coronary interventions by 20–30% (2) Improves diagnostic accuracy in intermediate lesions (…
https://news.gmj.ge/briefs/takeaway-functional-testing-reshapes-coronary-artery-disease-diagnosis-what-cardiologists-need-to-know/
https://news.gmj.ge/briefs/takeaway-functional-testing-reshapes-coronary-artery-disease-diagnosis-what-cardiologists-need-to-know/
Takeaway: Functional Testing Reshapes Coronary Artery Disease Diagnosis: What Cardiologists Need to Know
3 ways FFR-guided diagnosis is changing cardiology: (1) Reduces unnecessary coronary interventions by 20–30% (2) Improves diagnostic accuracy in intermediate lesions (…
news.gmj.ge
September 19, 2026 at 7:30 AM
3 ways FFR-guided diagnosis is changing cardiology: (1) Reduces unnecessary coronary interventions by 20–30% (2) Improves diagnostic accuracy in intermediate lesions (…
https://news.gmj.ge/briefs/takeaway-functional-testing-reshapes-coronary-artery-disease-diagnosis-what-cardiologists-need-to-know/
https://news.gmj.ge/briefs/takeaway-functional-testing-reshapes-coronary-artery-disease-diagnosis-what-cardiologists-need-to-know/
William Fearon and C. Michael Gibson break down the final 5-year follow-up of the study comparing FFR-guided PCI vs CABG for patients with three-vessel CAD. Listen to the full discussion: www.tctmd.com/audio/fame-3...
September 16, 2026 at 7:29 PM
William Fearon and C. Michael Gibson break down the final 5-year follow-up of the study comparing FFR-guided PCI vs CABG for patients with three-vessel CAD. Listen to the full discussion: www.tctmd.com/audio/fame-3...
The FAME 3 Trial
The FAME 3 Trial
The FAME 3 Trial
mosbey@crf.org
Wed, 09/16/2026 - 08:56
36 minutes 44 seconds hence
William Fearon and C. Michael Gibson break down the final 5-year follow-up of the study comparing FFR-guided PCI vs CABG for patients with three-vessel CAD.
www.tctmd.com
September 16, 2026 at 1:04 PM
The FAME 3 Trial
Clinical and economic impact of FFR-CT–guided management in moderate coronary artery disease: an interventional simulation study #recintervcardiol https://ow.ly/Y5vj50ZA71J
September 2, 2026 at 7:00 PM
Clinical and economic impact of FFR-CT–guided management in moderate coronary artery disease: an interventional simulation study #recintervcardiol https://ow.ly/Y5vj50ZA71J
【非責任領域FFR>0.8でPCIを見送ったSTEMI例の長期CV転帰は？/Int J Caridol】Aug.01
STEMIに対しFFRガイドPCI施行の280例、10.5年観察——
・非責任領域「FRR≦0.80」か「CAD狭窄≧90%」でPCIを「施行」
した群では、「FFR＞0.8」でPCR「見送り」群よりも「死亡・
MI・緊急血行再建」リスクが有意に低 [補正後HR 0.64]。発生率
は36 vs. 47%。
・PCI「見送り」群では「施行」群に比べ「CV死亡リスク」も有
意に高。
抄録🔗. x.gd/ZbHCH
STEMIに対しFFRガイドPCI施行の280例、10.5年観察——
・非責任領域「FRR≦0.80」か「CAD狭窄≧90%」でPCIを「施行」
した群では、「FFR＞0.8」でPCR「見送り」群よりも「死亡・
MI・緊急血行再建」リスクが有意に低 [補正後HR 0.64]。発生率
は36 vs. 47%。
・PCI「見送り」群では「施行」群に比べ「CV死亡リスク」も有
意に高。
抄録🔗. x.gd/ZbHCH
10-year outcome of fractional flow reserve-guided complete revascularization in patients with ST-segment elevation myocardial infarction – A DANAMI-3 PRIMULTI substudy
Complete revascularization is recommended in patients with ST-segment elevation myocardial
infarction (STEMI) and multivessel disease. However, whether the non-culprit lesions
should be evaluated usin...
x.gd
August 3, 2026 at 1:21 AM
【非責任領域FFR>0.8でPCIを見送ったSTEMI例の長期CV転帰は？/Int J Caridol】Aug.01
STEMIに対しFFRガイドPCI施行の280例、10.5年観察——
・非責任領域「FRR≦0.80」か「CAD狭窄≧90%」でPCIを「施行」
した群では、「FFR＞0.8」でPCR「見送り」群よりも「死亡・
MI・緊急血行再建」リスクが有意に低 [補正後HR 0.64]。発生率
は36 vs. 47%。
・PCI「見送り」群では「施行」群に比べ「CV死亡リスク」も有
意に高。
抄録🔗. x.gd/ZbHCH
STEMIに対しFFRガイドPCI施行の280例、10.5年観察——
・非責任領域「FRR≦0.80」か「CAD狭窄≧90%」でPCIを「施行」
した群では、「FFR＞0.8」でPCR「見送り」群よりも「死亡・
MI・緊急血行再建」リスクが有意に低 [補正後HR 0.64]。発生率
は36 vs. 47%。
・PCI「見送り」群では「施行」群に比べ「CV死亡リスク」も有
意に高。
抄録🔗. x.gd/ZbHCH
Among patients with intermediate coronary lesions, angiography-guided revascularization was noninferior to pressure-wire–based guidance with respect to death, myocardial infarction, or revascularization. Full FAST III trial results and Research Summary: https://nej.md/41rkAyp
July 6, 2026 at 4:00 PM
Among patients with intermediate coronary lesions, angiography-guided revascularization was noninferior to pressure-wire–based guidance with respect to death, myocardial infarction, or revascularization. Full FAST III trial results and Research Summary: https://nej.md/41rkAyp
FAST III: For patients with intermediate coronary lesions, whether outcomes of percutaneous revascularization guided by angiography-derived FFR are comparable to those guided by pressure-wire–derived FFR is unknown. Research findings are summarized in a new Quick Take video. https://nej.md/4y5W8Sv
July 3, 2026 at 7:00 PM
FAST III: For patients with intermediate coronary lesions, whether outcomes of percutaneous revascularization guided by angiography-derived FFR are comparable to those guided by pressure-wire–derived FFR is unknown. Research findings are summarized in a new Quick Take video. https://nej.md/4y5W8Sv
Over a 10-year period, FFR-guided PCI reduces rates of revascularization but not death compared with optimal medical therapy, a distinction that emphasizes that it's not a survival treatment, based on new meta-analysis. www.tctmd.com/news/ffr-gui...
#EuroPCR 2026
#EuroPCR 2026
FFR-Guided PCI Reduces Revascularization Over a Decade, but Not Death
A meta-analysis confirms what’s known: physiology-guided PCI is “not a survival treatment” when compared with OMT.
www.tctmd.com
May 29, 2026 at 7:50 PM
Over a 10-year period, FFR-guided PCI reduces rates of revascularization but not death compared with optimal medical therapy, a distinction that emphasizes that it's not a survival treatment, based on new meta-analysis. www.tctmd.com/news/ffr-gui...
#EuroPCR 2026
#EuroPCR 2026
Clinical and economic impact of FFR-CT–guided management in moderate coronary artery disease: an interventional simulation study #recintervcardiol #Aheadofprint
https://ow.ly/7KNv50YxQwc
https://ow.ly/7KNv50YxQwc
April 13, 2026 at 7:00 PM
Clinical and economic impact of FFR-CT–guided management in moderate coronary artery disease: an interventional simulation study #recintervcardiol #Aheadofprint
https://ow.ly/7KNv50YxQwc
https://ow.ly/7KNv50YxQwc
Revascularization treatment guided by fractional flow reserve calculated from an angiogram yielded similar outcomes as that guided by direct pressure wire measurement in randomized trials of two different software programs. #ACC26 www.medpagetoday.com/meetingcover...
Imaging-Based FFR on Par With Wire for PCI Outcomes
Two trials carve out a clear place for angiography-based fractional flow reserve in the cath lab
www.medpagetoday.com
March 30, 2026 at 6:21 PM
Revascularization treatment guided by fractional flow reserve calculated from an angiogram yielded similar outcomes as that guided by direct pressure wire measurement in randomized trials of two different software programs. #ACC26 www.medpagetoday.com/meetingcover...
FAST III: Vessel fractional flow reserve (vFFR)-guided revascularization was noninferior to pressure-wire-based FFR-guided revascularization in patients with intermediate coronary lesions.
🔥 Don’t miss the hottest science from #ACC26 ➡️ https://bit.ly/4sH53ql #CardioSky
🔥 Don’t miss the hottest science from #ACC26 ➡️ https://bit.ly/4sH53ql #CardioSky
March 29, 2026 at 3:13 PM
FAST III: Vessel fractional flow reserve (vFFR)-guided revascularization was noninferior to pressure-wire-based FFR-guided revascularization in patients with intermediate coronary lesions.
🔥 Don’t miss the hottest science from #ACC26 ➡️ https://bit.ly/4sH53ql #CardioSky
🔥 Don’t miss the hottest science from #ACC26 ➡️ https://bit.ly/4sH53ql #CardioSky
Coronary artery bypass grafting had arguably better early results for multivessel coronary artery disease when the surgery was guided by CT-based fractional flow reserve, according to the CABG-COREA randomized trial.
www.medpagetoday.com/meetingcover...
www.medpagetoday.com/meetingcover...
CT-Guided CABG Trial Feeds Early Enthusiasm
Reliance on CTA-derived FFR produced more perfectly patent grafts than QCA
www.medpagetoday.com
February 4, 2026 at 8:04 PM
Coronary artery bypass grafting had arguably better early results for multivessel coronary artery disease when the surgery was guided by CT-based fractional flow reserve, according to the CABG-COREA randomized trial.
www.medpagetoday.com/meetingcover...
www.medpagetoday.com/meetingcover...
A 10-year follow-up to the FAME 2 trial showed that treating physiologically important coronary lesions with PCI was linked to a significant reduction of all-cause mortality, MI, or urgent revascularization, driven by the decrease in revascularization. More here: www.tctmd.com/news/fame-2-...
FAME 2 at 10 Years: Less Urgent Revascularization With FFR-Guided PCI
With no difference in death or MI, Kevin Bainey says doctors can give medical therapy a good try before sending patients for PCI.
www.tctmd.com
February 2, 2026 at 3:00 PM
A 10-year follow-up to the FAME 2 trial showed that treating physiologically important coronary lesions with PCI was linked to a significant reduction of all-cause mortality, MI, or urgent revascularization, driven by the decrease in revascularization. More here: www.tctmd.com/news/fame-2-...
CT-Guided CABG Trial Feeds Early Enthusiasm
(MedPage Today) -- NEW ORLEANS -- Coronary artery bypass grafting (CABG) had arguably better early results for multivessel coronary artery disease (CAD) when the surgery was guided by CT-based fractional flow reserve (FFR), according to the CABG...…
(MedPage Today) -- NEW ORLEANS -- Coronary artery bypass grafting (CABG) had arguably better early results for multivessel coronary artery disease (CAD) when the surgery was guided by CT-based fractional flow reserve (FFR), according to the CABG...…
CT-Guided CABG Trial Feeds Early Enthusiasm
(MedPage Today) -- NEW ORLEANS -- Coronary artery bypass grafting (CABG) had arguably better early results for multivessel coronary artery disease (CAD) when the surgery was guided by CT-based fractional flow reserve (FFR), according to the CABG... Source link
aitrendus.com
January 31, 2026 at 11:54 PM
CT-Guided CABG Trial Feeds Early Enthusiasm
(MedPage Today) -- NEW ORLEANS -- Coronary artery bypass grafting (CABG) had arguably better early results for multivessel coronary artery disease (CAD) when the surgery was guided by CT-based fractional flow reserve (FFR), according to the CABG...…
(MedPage Today) -- NEW ORLEANS -- Coronary artery bypass grafting (CABG) had arguably better early results for multivessel coronary artery disease (CAD) when the surgery was guided by CT-based fractional flow reserve (FFR), according to the CABG...…
Takayasu Arteritis-Induced Acute Myocardial Infarction: Coronary Imaging- and Physiology-Guided Management
Takayasu Arteritis-Induced Acute Myocardial Infarction: Coronary Imaging- and Physiology-Guided Management - PubMed
In young women with MI, nonatherosclerotic causes should be considered. IVUS and FFR can aid diagnosis and help avoid unnecessary coronary intervention.
pubmed.ncbi.nlm.nih.gov
January 29, 2026 at 8:15 PM
Takayasu Arteritis-Induced Acute Myocardial Infarction: Coronary Imaging- and Physiology-Guided Management
FAME 2 at 10 Years: Less Urgent Revascularization With FFR-Guided PCI
FAME 2 at 10 Years: Less Urgent Revascularization With FFR-Guided PCI
FAME 2 at 10 Years: Less Urgent Revascularization With FFR-Guided PCI
cmacahilig@crf.org
Mon, 01/26/2026 - 16:52
Michael O'Riordan
With no difference in death or MI, Kevin Bainey says doctors can give medical therapy a good try before sending patients for PCI.
www.tctmd.com
January 26, 2026 at 10:00 PM
FAME 2 at 10 Years: Less Urgent Revascularization With FFR-Guided PCI
Long-term follow-up of the FAME 2 trial shows FFR-guided PCI plus medical therapy reduces cardiovascular events vs medical therapy alone.
https://www.nature.com/articles/s41591-025-04132-5
https://www.nature.com/articles/s41591-025-04132-5
January 24, 2026 at 7:00 PM
Long-term follow-up of the FAME 2 trial shows FFR-guided PCI plus medical therapy reduces cardiovascular events vs medical therapy alone.
https://www.nature.com/articles/s41591-025-04132-5
https://www.nature.com/articles/s41591-025-04132-5
FFR-guided PCI slashes long-term risks in stable CAD, outperforming medical therapy by reducing urgent revascularizations significantly.
by Collet C, Mahendiran T (...) Jüni P et 27 al. in Nat Med #MedSky
👉 get more here
📖 read the article:
by Collet C, Mahendiran T (...) Jüni P et 27 al. in Nat Med #MedSky
👉 get more here
📖 read the article:
Fractional flow reserve-guided percutaneous coronary intervention versus medical therapy for stable coronary artery disease: long-term results of the FAME 2 trial - Nature Medicine
In a long-term follow-up of the FAME 2 trial, fractional flow reserve-guided percutaneous coronary intervention plus medical therapy in patients with stable coronary artery disease reduced cardiovascular events compared to medical therapy alone, primarily due to a decrease in urgent revascularization events.
www.nature.com
January 24, 2026 at 8:41 AM
Long-term follow-up of the FAME 2 trial shows FFR-guided PCI plus medical therapy reduces cardiovascular events vs medical therapy alone.
https://www.nature.com/articles/s41591-025-04132-5
https://www.nature.com/articles/s41591-025-04132-5
January 16, 2026 at 2:02 PM
Long-term follow-up of the FAME 2 trial shows FFR-guided PCI plus medical therapy reduces cardiovascular events vs medical therapy alone.
https://www.nature.com/articles/s41591-025-04132-5
https://www.nature.com/articles/s41591-025-04132-5
【安定CADに対するFFRガイドPCIの優越性は11年後も維持：FAME2/Nat Med】Jan15
欧米、安定感動脈疾患1.220例ランダム化、11.2年 [中央値] 観察可能だった748例解析——
・「死亡・MI・緊急血行再建」は、FFRガイドPCI群で33.6%、至
適薬剤治療群は41.3%。Win Ratioで有意差。
抄録🔗 x.gd/u58uH
欧米、安定感動脈疾患1.220例ランダム化、11.2年 [中央値] 観察可能だった748例解析——
・「死亡・MI・緊急血行再建」は、FFRガイドPCI群で33.6%、至
適薬剤治療群は41.3%。Win Ratioで有意差。
抄録🔗 x.gd/u58uH
Fractional flow reserve-guided percutaneous coronary intervention versus medical therapy for stable coronary artery disease: long-term results of the FAME 2 trial - Nature Medicine
In a long-term follow-up of the FAME 2 trial, fractional flow reserve-guided percutaneous coronary intervention plus medical therapy in patients with stable coronary artery disease reduced cardiovascu...
x.gd
January 15, 2026 at 11:38 PM
【安定CADに対するFFRガイドPCIの優越性は11年後も維持：FAME2/Nat Med】Jan15
欧米、安定感動脈疾患1.220例ランダム化、11.2年 [中央値] 観察可能だった748例解析——
・「死亡・MI・緊急血行再建」は、FFRガイドPCI群で33.6%、至
適薬剤治療群は41.3%。Win Ratioで有意差。
抄録🔗 x.gd/u58uH
欧米、安定感動脈疾患1.220例ランダム化、11.2年 [中央値] 観察可能だった748例解析——
・「死亡・MI・緊急血行再建」は、FFRガイドPCI群で33.6%、至
適薬剤治療群は41.3%。Win Ratioで有意差。
抄録🔗 x.gd/u58uH
🫀 Dive into donor vessel physiology changes post-CCTA guided CTO PCI—CT-FFR & #AI ischemia at #IJCVI!
🌐
🌐
Changes in donor vessel physiology following coronary computed tomography angiography guided chronic total occlusion percutaneous coronary intervention: insights from computed tomography fractional flow reserve and artificial intelligence-guided ischemia model
The International Journal of Cardiovascular Imaging - Donor vessel fractional flow reserve (FFR) usually increases following successful chronic total occlusion (CTO) percutaneous coronary...
doi.org
December 23, 2025 at 3:30 PM