a, Immunoblotting of MFF in CRISPR Ctrl, MFF KO and MFF-reconstructed HeLa cells. b, Viability of cells in a after RSL3 for 24 h or erastin for 48 h. c, GSH/GSSG ratios in wild-type or MFF KO HeLa cells treated with 200 nM RSL3 or 2 µM FINO2 for 6 h, with or without 2 µM Lip-1 pretreatment for 0.5 h. d, Cell death in CRISPR Ctrl, MFF KO and MFF-rescued HeLa cells treated with vehicle, 50 µM hemin for 48 h, or hemin after 100 µM DFO pretreatment for 0.5 h. e, Cell death in CRISPR Ctrl or MFF KO cells treated for 24 h with organic peroxides (20 µM TBHP, 10 µM CHP or 50 µM BPO) or 250 µM H2O2, with or without Lip-1 as indicated. f,g, Cell density (f) and EdU incorporation (g) in wild-type or MFF KO HeLa cells. Scale bars, 50 µm. h, Immunoblotting and cell viability in HeLa, HT-1080, SH-SY5Y, HepG2 and A549 cells expressing shNC or MFF-targeting shRNAs after RSL3 treatment for 24 h. i,j, Viability of HeLa cells expressing shNC or MFF-targeting shRNAs after STS or TNFα + CHX (i), or TNFα + CHX+zVAD (j), for 24 h. k, LDH release...

Em 9 de julho, a Samsung Electronics apresentou a nova linha Galaxy Watch8, com o Galaxy Watch8 e o Galaxy Watch8 Classic1, durante o Galaxy Unpacked 2025, em Nova York (Estados Unidos). Conforme o bem-estar pessoal se torna cada vez mais importante, o Galaxy Watch8 apresenta recursos de saúde mais inteligentes e o design mais fino2 que apoia o bem-estar diário3.