#FinnDiane
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folkhalsanresearch.bsky.social
In our genetic sequencing study of over 1,000 FinnDiane study participants with type 1 diabetes, we uncovered clues that might help understand why some of the individuals develop diabetic kidney disease.
@finndiane.bsky.social
#FolkhälsanResearch
research.folkhalsan.fi/annual-repor...
May 7, 2025 at 6:07 AM
finndiane.bsky.social
Congratulations to FinnDiane researcher @emmadahlstrom.bsky.social for receiving the rising star Harry Keen award at the annual meeting of the EDNSG!
May 16, 2025 at 9:38 AM
niinasandholm.bsky.social
Our GWAS on urine metabolomics revealed novel genes and pathways affecting urine metabolites and evaluated the role of kidney function. Great collaboration between FinnDiane Study, Generation Scotland and the VIKING STUDY! rdcu.be/d5oZQ
Genome-wide characterization of 54 urinary metabolites reveals molecular impact of kidney function
Nature Communications - Here, the authors identified genetic variants associated with urinary metabolites in 8,011 individuals. Further causal analysis suggested estimated kidney filtration rate...
rdcu.be
January 13, 2025 at 4:08 PM
folkhalsanresearch.bsky.social
Emma Dahlström from the FinnDiane Study has been awarded the ”Rising Star – Harry Keen Award” by the European Diabetic Nephropathy Study Group, in recognition of her contributions as a young researcher. Congratulations, Emma!
@emmadahlstrom.bsky.social @finndiane.bsky.social
#EDNSG
May 21, 2025 at 6:25 AM
niinasandholm.bsky.social
What a great week at the #EASD2025! Inspiring science and proud to see the many FinnDiane presentations, including the early career awardee Anniina!
finndiane.bsky.social FinnDiane @finndiane.bsky.social · Sep 19
Congratulations to Anniina Tynjälä for winning a best early career abstract at #EASD2025 for her work on the genetic background of arterial stiffness in type 1 diabetes
September 23, 2025 at 5:56 AM
diabetologiajnl.bsky.social
sRAGE is closely linked to obesity but is not related to changes in obesity over time. Stay tuned for insights into its role in obesity and type 1 diabetes! #sRAGE and Obesity, #FinnDiane Study link.springer.com/article/10.1... 🔓
Relationship between sRAGE and obesity in individuals with type 1 diabetes during a median follow-up of 6.3 years - Diabetologia
Aims/hypothesis Soluble receptor for advanced glycation end products (sRAGE) has been inversely linked to obesity, which is defined by excess of total body fat. However, body fat accumulation is also ...
link.springer.com
May 9, 2025 at 10:46 AM
finndiane.bsky.social
STEMI rates are falling in type 1 diabetes 📉 but NSTEMI rates are not📈 New data from the FinnDiane cohort show these two myocardial infarction subtypes have distinct risk profiles, with microvascular complications playing a key role in NSTEMI @helsinki.fi ➡️ www.thelancet.com/journals/lan...
Comparison of incidence patterns and risk profiles of ST-elevation and non-ST-elevation myocardial infarction in type 1 diabetes in Finland: a nationwide cohort study
We report that STEMI and NSTEMI exhibit different incidence patterns depending on age and year of myocardial infarction. STEMI and NSTEMI also differed regarding risk profiles, demonstrating that myoc...
www.thelancet.com
March 25, 2026 at 1:24 PM
finndiane.bsky.social
Today is #WorldDiabetesDay! The #FinnDiane Study highlights that reducing sitting at work can help people with #Type1Diabetes maintain cardiovascular health doi.org/10.1186/s129... Let’s make workplaces healthier for people with #diabetes: move more, sit less! #DiabetesAndTheWorkplace
Excessive occupational sitting increases risk of cardiovascular events among working individuals with type 1 diabetes in the prospective Finnish Diabetic Nephropathy Study - Cardiovascular Diabetology
Background Sedentary behavior, such as excessive sitting, increases risk of cardiovascular disease and premature mortality in the general population, but this has not been assessed in type 1 diabetes....
doi.org
November 14, 2025 at 12:14 PM
finndiane.bsky.social
Excited to share our latest #article! We conducted the largest NGS study to date on SDR in type 1 diabetes, identifying rare variants in genes like AFAP1L1, SLC30A9, HPS3, PELI1 and CSMD2.
🔗 iovs.arvojournals.org/article.aspx...
@folkhalsanresearch.bsky.social #FinnDiane #T1D #retinopathy #diabetes
Exome and Genome Sequencing Reveals Novel Variants for Severe Diabetic Retinopathy in Type 1 Diabetes | IOVS | ARVO Journals
iovs.arvojournals.org
November 5, 2025 at 12:46 PM
niinasandholm.bsky.social
See our study on HMXO1 GTn repeat and heme oxogenase-1 concentrations in #FinnDiane participants with #T1D, collaboration with Lakkisto Lab! HMOX1 LL genotype was associated with cardiac events and mortality in men with #T1D, but not in women. #FolkhälsanResearch @finndiane.bsky.social rdcu.be/eBh3i
Heme oxygenase-1 polymorphisms associate with ischemic cardiac complications and all-cause mortality in type 1 diabetes
rdcu.be
August 21, 2025 at 10:59 AM
adapubs.bsky.social
A discrepancy between cystatin C- and creatinine-based eGFR identifies early risk of heart failure, peripheral artery disease, and mortality in individuals with type 1 diabetes without albuminuria.

Read here ➡️ doi.org/10.2337/dc25-2987
The image contains an infographic summarizing a study titled "3,769 Finnish Diabetic Nephropathy (FinnDiane) Study participants with type 1 diabetes." It includes three sections: 1. **Left Section**: Describes the assessment of cystatin C and creatinine-based eGFR, and the eGFRcys/eGFRcr ratio. It lists outcomes like coronary artery disease, stroke, heart failure, and all-cause mortality, accompanied by an anatomical diagram. 2. **Middle Section**: Highlights findings that eGFRcys and the eGFRcys/eGFRcr ratio are linked with CAD, stroke, PAD, HF, and all-cause mortality in individuals with albuminuria. 3. **Right Section**: Discusses the association of lower eGFRcys and eGFRcys alone with increased risk of HF and all-cause mortality in individuals without albuminuria. It also states that the ratio was not linked with any outcomes. Includes some illustrative graphs.
April 5, 2026 at 9:40 PM
finndiane.bsky.social
New findings from the FinnDiane Study: Fracture risk in type 1 diabetes is increased from a young age and rises markedly with diabetic kidney disease. The highest risk was seen in kidney failure. Bone health may need attention earlier than current guidelines suggest.
Fracture Risk Is Increased in Type 1 Diabetes and Is the Highest in Individuals With Diabetic Kidney Disease
OBJECTIVE. To quantify the excess risk of any fractures, major osteoporotic fractures (MOF), and hip fractures in type 1 diabetes (T1D) by age, stages of d
diabetesjournals.org
August 20, 2026 at 10:24 AM
folkhalsanresearch.bsky.social
Per-Henrik Groop is Group Leader Emeritus of the FinnDiane (Finnish Diabetic Nephropathy) Study at Folkhälsan Research Center. For almost 40 years, Groop has built an outstanding career in the fields of internal medicine and nephrology.
August 26, 2025 at 8:26 AM
finndiane.bsky.social
New #FinnDiane publication. Chronic low-grade inflammation adds to the coronary artery disease risk from metabolic syndrome in type 1 diabetes, but only in those WITHOUT DKD. Managing metabolic risk factors early and screening for chronic low-grade inflammation offer improved risk stratification.
Redirecting
doi.org
May 8, 2026 at 9:12 AM
finndiane.bsky.social
New findings from the FinnDiane study: central obesity in type 1 diabetes matters. Even a 0.1-unit increase in waist-to-height ratio was associated with a 21% higher risk of coronary artery disease, and the association was most pronounced among those without kidney disease. doi.org/10.2337/dc25...
Waist-to-Height Ratio Is Associated With the Risk of Coronary Artery Disease in Type 1 Diabetes: A 19-Year Cohort Study
Obesity, kidney disease, and coronary artery disease (CAD) are interconnected. Here, the relationship between central obesity and CAD across albuminuria ca
doi.org
April 20, 2026 at 11:24 AM
adapubs.bsky.social
New findings from the FinnDiane Study show that central obesity increases the risk of coronary artery disease in people with type 1 diabetes. #T1D #Cardiology #Obesity #WHtR

Read here ➡️ doi.org/10.2337/dc25-2811
The image is an infographic about a 19-year cohort study on the association between waist-to-height ratio (WHtR) and coronary artery disease (CAD) in type 1 diabetes. It includes statistics such as "N = 4,349 participants from the FinnDiane Study" and "The 20-year cumulative CAD incidence was 25.3% for central obesity versus 9.9% otherwise." It highlights that a 0.1-unit increase in WHtR raised CAD risk by 21% and by 26% for those with central obesity. The infographic promotes using WHtR as a tool to assess CAD risk in type 1 diabetes patients.
April 29, 2026 at 2:40 PM
medrxivpreprint.bsky.social
FinnDiane LifeOne Study - Impact of ageing on people with type 1 diabetes, a prospective observational cohort study https://www.medrxiv.org/content/10.64898/2026.05.06.26352532v1
May 7, 2026 at 10:55 PM
kaththomasset.bsky.social
Data from the #FinnDiane study on links between souble receptor for AGEs and obesity #T1D #Diabetes #DiabetesResearch #Endocrinology #MedSky
May 9, 2025 at 2:24 PM