#Pericrine #Angiogenesis

#Pericyte-derived TIMP3
⏫ #EndothelialCell tubulogenesis (⏬EC cord diameter ⏫length branching basement membrane) in a 3D collagen EC-pericyte co-culture model

#FrontCellDevBio 2024
@ondinecleaver.bsky.social
www.frontiersin.org/journals/cel...

#SchlemmsCanal Inlet Valve

An intricate endothelial tubular structure resembling #IntussusceptivePillar, but with a patent lumen for #AqueousHumor drainage👁️

BABB-cleared primate👁️ (anterior segment)

#SciArt
Murray Johnston lab #FrontCellDevBio 2022
www.frontiersin.org/journals/cel...

The spatial proximity & apical-basal (luminal-abluminal) polarity of #Pericyte #EndoplasmicReticulum positioning to Pericyte-Endothelial Cell Peg-Socket Junctions

3 capillaries
Axial cross-sections with isotropic (X-Y) 4 nm pixel size
H01

#FrontCellDevBio 2026
www.frontiersin.org/journals/cel...

My continued biological education

Mechanisms of Alkaliptosis
pH-dependent, caspase/MLKL/GPX4/Autophagy-independent cell death

Pharma inducer:
JTC801

Tumor:
PDAC
AML

Pathway:
NF-κB-CA9
ATP6V0D1-STAT3

#FrontCellDevBio 2023
www.frontiersin.org/journals/cel...

Podocin interactome 54 proteins
Kidney #SlitDiaphragm

Pocodin/Nphs2-BioID2🐭

Discovering novel, age-related #PodocyteFootProcess protien - ILDR2 #TricellularJunction protein

FNBP1L, formin-binding protein

@llobrienlab.bsky.social #FrontCellDevBio 2023
www.frontiersin.org/articles/10....

Injure the Heart of Ciona intestinalis #SeaVase!?

A very interesting transcriptomics analysis
20-fold⏫Fgf9/16/20 transcript😀

Thickening of myocardium at 48 h post-ligation. myocyte hypertrophic, proliferative, or inflammed!?🧐

#FrontCellDevBio 2024
www.frontiersin.org/articles/10....

#NEUBIAS guys on stage, JACOP & SR-Tesseler in action @fab_cordelieres @f_levet https://x.com/FrontCellDevBio/status/1327033950137511944

#FGF9 Adhesive Capsulitis
cytoHubba➡️FGF9 as an AC hub gene

FGF9 ⬆️in 👤AC glenohumeral joint capsule & 🐭Shoulder Stiffness (joint immobilization)
Which cell type?🧐
& FGF9 Ab info?😳

FGF9 ⏫fibroblast proliferation migration & αSMA level

#FrontCellDevBio 2025
www.frontiersin.org/journals/cel...

scRNAseq #EndothelialCell in Ldlr-/- 🐭#DiabeticAtherosclerosis

Does the diabetogenic #HighFatDiet+cholesterol produce a more severe (or unique) mode of #EndMT than conventional HFD?

Do EndMT subclusters display altered insulin signaling?

#FrontCellDevBio 2021
www.frontiersin.org/articles/10....

Dr Sophie Wiszniak from @CCB_Research is currently editing a special issue of @FrontCellDevBio on cellular interactions during tissue-specific vascularisation. Check out the link to contribute.

#NeuroPSI_Publications. Great new findings by @elfisho in the @DECAteam1 on the impact of early development on eye loss in their favorite fish Astyanax mexicanus! Now online in @FrontCellDevBio. #evolution

frontiersin.org/article/10.338…

The review also has comprehensive descriptions of the structure and function of the receptor. Along with how it was discovered and how it came to be ✨

There's more about wound healing 🩹 in there too, with a special focus on zebrafish 🐟 research! @FrontCellDevBio