#GORTEC
NIVOPOSTOP (GORTEC 2018-01): A Phase III Trial of Adjuvant Nivolumab in High-Risk Resected Head and Neck Squamous Cell Carcinoma

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#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #NIVOPOSTOP #HNSCC #HeadNeckCancer
NIVOPOSTOP (GORTEC 2018-01): A Phase III Trial of Adjuvant Nivolumab in High-Risk Resected Head and Neck Squamous Cell Carcinoma - OncoDaily
NIVOPOSTOP trial shows adjuvant nivolumab improves disease-free survival after chemoradiotherapy in high-risk resected head and neck cancer.
oncodaily.com
May 2, 2025 at 9:13 PM
Second up! Dr. Jean Bourhis Sr presents NIVOPOSTOP (GORTEC 2018-01): chemoRT +/- nivolumab for resected, high risk head and neck squamous cell carcinoma. 24% risk reduction in disease progression or death: 3-year DFS 63.1 vs 52.5 months (HR 0.76) with substantial drop in locoregional relapse #ASCO25
June 1, 2025 at 6:45 PM
This is a fascinating trial
Same survival chemo-SABR 42.3 months vs SABR-alone 41.1 months in #hncsm patients with oligomets
GORTEC 2014-04 “OMET” Randomized Phase 2 Trial in Head and Neck Cancer Patients with Oligometastases using SABR-alone or chemotherapy-SABR
👉 www.redjournal.org/article/S036...
DEFINE_ME
www.redjournal.org
November 30, 2024 at 12:58 AM
NIVOPOSTOP (GORTEC 2018-01): Ph3 RCT of adjuvant nivolumab added to radio-chemotherapy in Pts w/ resected head & neck squamous cell carcinoma at high risk of relapse - Bourhis et al. #ASCO25 LBA2 meetings.asco.org/abstracts-pr... #NCT03576417 #hncsm #ImmunoOnc
Program Guide – ASCO Meeting Program Guide
meetings.asco.org
April 23, 2025 at 7:20 PM

Nivolumab Improves DFS in High-Risk Head & Neck SCC

The Phase 3 NIVOPOSTOP trial (680 patients) showed that adding nivolumab to standard post-op CRT significantly improved DFS in resected LA-SCCHN with high relapse risk. A trend toward better OS was observed, pending final analysis.
GORTEC Announces New Trial Success for Head and Neck Cancer Treatment
/PRNewswire/ -- GORTEC, known as Head and Neck Radiation Oncology Group, today announced that the randomized Phase 3 NIVOPOSTOP GORTEC 2018-01 trial evaluating...
www.prnewswire.com
January 10, 2025 at 2:20 PM
Nivolumab added to cisplatin and radiotherapy versus cisplatin and radiotherapy alone after surgery for people with squamous cell carcinoma of the head and neck at a high risk of relapse (GORTEC 2018-01 NIVOPOST-OP): a randomised, open-label, phase 3 trial. www.thelancet.com/journals/lan...
Nivolumab added to cisplatin and radiotherapy versus cisplatin and radiotherapy alone after surgery for people with squamous cell carcinoma of the head and neck at a high risk of relapse (GORTEC 2018-...
Nivolumab added to cisplatin and radiotherapy in high-risk resected LA-SCCHN improves disease-free survival with moderate toxic effect increase, and can be proposed as a new standard treatment.
www.thelancet.com
January 8, 2026 at 2:19 PM
GORTEC's Phase 3 Trial Shows Promising Results for Head and Neck Cancer Treatment#USA#GORTEC#Nivolumab#Head_and_Neck_Cancer#Tours
GORTEC's Phase 3 Trial Shows Promising Results for Head and Neck Cancer Treatment
GORTEC announces significant findings from their Phase 3 trial on nivolumab for head and neck cancer, marking a breakthrough in treatment options.
third-news.com
January 7, 2025 at 1:16 PM
GORTEC's Phase 3 Trial Demonstrates Breakthrough in Head and Neck Cancer Treatment#France#GORTEC#Nivolumab#Head_and_Neck_Cancer#Tours
GORTEC's Phase 3 Trial Demonstrates Breakthrough in Head and Neck Cancer Treatment
GORTEC has announced successful results from its Phase 3 trial, NIVOPOSTOP GORTEC 2018-01, showcasing improved outcomes for head and neck cancer patients.
third-news.com
January 7, 2025 at 1:12 PM