(1/4) Congrats @estebanezlab.bsky.social & team for your new paper deciphering the mechanism determining #GlucocorticoidReceptor complex @bqbiomedmolub.bsky.social @biologiaub.bsky.social
web.ub.edu/en/web/actua...
web.ub.edu/en/web/actua...
Researchers decipher a mechanism that determines the complexity of the glucocorticoid receptor
web.ub.edu
November 18, 2025 at 8:36 AM
(1/4) Congrats @estebanezlab.bsky.social & team for your new paper deciphering the mechanism determining #GlucocorticoidReceptor complex @bqbiomedmolub.bsky.social @biologiaub.bsky.social
web.ub.edu/en/web/actua...
web.ub.edu/en/web/actua...
(4/4) #XLMS results support the structural analyses done by Eva’s team, which uncovered how the #GlucocorticoidReceptor (GR) self-assembles into its active forms. This deepens into the understanding of disease-linked GR mutations and establishes a framework for designing selective GR modulators.
November 18, 2025 at 8:36 AM
(4/4) #XLMS results support the structural analyses done by Eva’s team, which uncovered how the #GlucocorticoidReceptor (GR) self-assembles into its active forms. This deepens into the understanding of disease-linked GR mutations and establishes a framework for designing selective GR modulators.
Online today! Activated #GlucocorticoidReceptor is an #EstrogenReceptor silencer in ER+ metastatic #BreastCancer
By M. Manivannan, C. Jehanno, @momobentires.bsky.social and colleagues @unibas.ch
👉 doi.org/10.1038/s443...
By M. Manivannan, C. Jehanno, @momobentires.bsky.social and colleagues @unibas.ch
👉 doi.org/10.1038/s443...
November 19, 2025 at 8:33 PM
Online today! Activated #GlucocorticoidReceptor is an #EstrogenReceptor silencer in ER+ metastatic #BreastCancer
By M. Manivannan, C. Jehanno, @momobentires.bsky.social and colleagues @unibas.ch
👉 doi.org/10.1038/s443...
By M. Manivannan, C. Jehanno, @momobentires.bsky.social and colleagues @unibas.ch
👉 doi.org/10.1038/s443...
The #glucocorticoidreceptor is a primary stress hormone receptor, activated by the agonist corticosterone in rodents & cortisol in humans. Chronic elevated CORT is sufficient to drive the loss of flexible behaviours.
July 25, 2025 at 7:24 AM
The #glucocorticoidreceptor is a primary stress hormone receptor, activated by the agonist corticosterone in rodents & cortisol in humans. Chronic elevated CORT is sufficient to drive the loss of flexible behaviours.
#oncology #womenshealth #CorceptTherapeutics #relacorilant #ovariancancer #cancerinwomen #cortisolmodulatingmedications #platinumresistantovariancancer #ROSELLAtrial #gynaecologicalcancerresearch #glucocorticoidreceptor #cortisolmodulatingtreatments
zurl.co/JWBM3
zurl.co/JWBM3
Corcept Therapeutics’ relacorilant plus nab-paclitaxel shows positive results in ovarian cancer - PharmaTimes
Ovarian cancer is the fifth leading cause of deaths from cancer in women
pharmatimes.com
January 26, 2026 at 12:37 PM
New article about #epigenetic changes in a #glucocorticoidreceptor that is important for #stressresponse and that is more methylated in mothers exposed to #intimatepartnerviolence and which may have the potential to confer #vulnerability for #psychopathologies
👇🏻👇🏻👇🏻👇🏻
👇🏻👇🏻👇🏻👇🏻
February 20, 2025 at 11:07 AM
New article about #epigenetic changes in a #glucocorticoidreceptor that is important for #stressresponse and that is more methylated in mothers exposed to #intimatepartnerviolence and which may have the potential to confer #vulnerability for #psychopathologies
👇🏻👇🏻👇🏻👇🏻
👇🏻👇🏻👇🏻👇🏻
JAK/STAT inhibition protects #GlucocorticoidReceptor knockout mice from lethal #malaria -induced hypoglycemia and hyperinflammation
By F. Prenen, L. Vandermosten, P. Van den Stehen & colleagues at Rega Institute for Medical Research KU Leuven
➡️ doi.org/10.1038/s443...
By F. Prenen, L. Vandermosten, P. Van den Stehen & colleagues at Rega Institute for Medical Research KU Leuven
➡️ doi.org/10.1038/s443...
July 23, 2025 at 4:00 PM
JAK/STAT inhibition protects #GlucocorticoidReceptor knockout mice from lethal #malaria -induced hypoglycemia and hyperinflammation
By F. Prenen, L. Vandermosten, P. Van den Stehen & colleagues at Rega Institute for Medical Research KU Leuven
➡️ doi.org/10.1038/s443...
By F. Prenen, L. Vandermosten, P. Van den Stehen & colleagues at Rega Institute for Medical Research KU Leuven
➡️ doi.org/10.1038/s443...