So proud: another mystery of the #brain #gridcells discovered the #sweeps in our lab by - @azwollan.bsky.social @rjgardner.bsky.social
@edvardmoser.bsky.social at
@kavlintnu.bsky.social
@torilhernes.bsky.social
@kavlifondation.bsky.social
🧹🔦🍩🐀
@edvardmoser.bsky.social at
@kavlintnu.bsky.social
@torilhernes.bsky.social
@kavlifondation.bsky.social
🧹🔦🍩🐀
Grid cells have a geometry in time. Thanks to @azvollan.bsky.social l & @rjgardner.bsky.social for this heroic discovery. @ercresearch.bsky.social
#KiloNeurons @m-bmoser.bsky.social @kavlintnu.bsky.social @nature.com
@kavlifoundation.bsky.social
www.nature.com/articles/s41...
#KiloNeurons @m-bmoser.bsky.social @kavlintnu.bsky.social @nature.com
@kavlifoundation.bsky.social
www.nature.com/articles/s41...
Left–right-alternating theta sweeps in entorhinal–hippocampal maps of space - Nature
A study in rats proposes a mechanism for how the brain maps the surrounding environment, including places it has never seen, by alternating left and right forward sweeps in successive theta cycles.
www.nature.com
February 3, 2025 at 4:20 PM
So proud: another mystery of the #brain #gridcells discovered the #sweeps in our lab by - @azwollan.bsky.social @rjgardner.bsky.social
@edvardmoser.bsky.social at
@kavlintnu.bsky.social
@torilhernes.bsky.social
@kavlifondation.bsky.social
🧹🔦🍩🐀
@edvardmoser.bsky.social at
@kavlintnu.bsky.social
@torilhernes.bsky.social
@kavlifondation.bsky.social
🧹🔦🍩🐀
So happy to release this to the world!! A big one that's been cooking for years.
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇
1/5 How does the brain turn the low-dimensional, universal grid cell metric into the rich, diverse codes needed for memory in hippocampal place cells? 🧵
Preprint link 👇
www.biorxiv.org/content/10.1...
Preprint link 👇
www.biorxiv.org/content/10.1...
Functional independence of entorhinal grid cell modules enables remapping in hippocampal place cells
A systems-level understanding of cortical computation requires insight into how neural codes are transformed across distinct brain circuits. In the mammalian cortex, one of the few systems where such ...
www.biorxiv.org
September 25, 2025 at 4:26 AM
So happy to release this to the world!! A big one that's been cooking for years.
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇
5/5 Big thanks to the team and collaborators @clykken.bsky.social @beneuroscience.bsky.social @anagelhus.bsky.social @jocarpenter.bsky.social @matteoguardamagna.bsky.social @m-bmoser.bsky.social @kavlintnu.bsky.social
#Neuroscience #GridCells #PlaceCells #EpisodicMemory #Neuropixels #KiloNeurons
#Neuroscience #GridCells #PlaceCells #EpisodicMemory #Neuropixels #KiloNeurons
September 25, 2025 at 4:06 AM
How does the 🧠-map choose what to sample?
Preprint: #Sweeps in #gridcells act as attention-like signal, dynamically biasing the map towards behaviourally relevant locations.
By @mschellenberger.bsky.social @azvollan.bsky.social @m-bmoser.bsky.social @edvardmoser.bsky.social + @rjgardner.bsky.social
Preprint: #Sweeps in #gridcells act as attention-like signal, dynamically biasing the map towards behaviourally relevant locations.
By @mschellenberger.bsky.social @azvollan.bsky.social @m-bmoser.bsky.social @edvardmoser.bsky.social + @rjgardner.bsky.social
The hippocampal map has its own attentional control signal!
Our new study reveals that theta #sweeps can be instantly biased towards behaviourally relevant locations. See 📹 in post 4/6 and preprint here 👉
www.biorxiv.org/content/10.6...
🧵(1/6)
Our new study reveals that theta #sweeps can be instantly biased towards behaviourally relevant locations. See 📹 in post 4/6 and preprint here 👉
www.biorxiv.org/content/10.6...
🧵(1/6)
Attention-like regulation of theta sweeps in the brain's spatial navigation circuit
Spatial attention supports navigation by prioritizing information from selected locations. A candidate neural mechanism is provided by theta-paced sweeps in grid- and place-cell population activity, which sample nearby space in a left-right-alternating pattern coordinated by parasubicular direction signals. During exploration, this alternation promotes uniform spatial coverage, but whether sweeps can be flexibly tuned to locations of particular interest remains unclear. Using large-scale Neuropixels recordings in freely-behaving rats, we show that sweeps and direction signals are rapidly and dynamically modulated: they track moving targets during pursuit, precede orienting responses during immobility, and reverse during backward locomotion — without prior spatial learning. Similar modulation occurs during REM sleep. Canonical head-direction signals remain head-aligned. These findings identify sweeps as a flexible, attention-like mechanism for selectively sampling allocentric cognitive maps. ### Competing Interest Statement The authors have declared no competing interest. European Research Council, Synergy Grant 951319 (EIM) The Research Council of Norway, Centre of Neural Computation 223262 (EIM, MBM), Centre for Algorithms in the Cortex 332640 (EIM, MBM), National Infrastructure grant (NORBRAIN, 295721 and 350201) The Kavli Foundation, https://ror.org/00kztt736 Ministry of Science and Education, Norway (EIM, MBM) Faculty of Medicine and Health Sciences; NTNU, Norway (AZV)
www.biorxiv.org
January 28, 2026 at 10:18 AM
How does the 🧠-map choose what to sample?
Preprint: #Sweeps in #gridcells act as attention-like signal, dynamically biasing the map towards behaviourally relevant locations.
By @mschellenberger.bsky.social @azvollan.bsky.social @m-bmoser.bsky.social @edvardmoser.bsky.social + @rjgardner.bsky.social
Preprint: #Sweeps in #gridcells act as attention-like signal, dynamically biasing the map towards behaviourally relevant locations.
By @mschellenberger.bsky.social @azvollan.bsky.social @m-bmoser.bsky.social @edvardmoser.bsky.social + @rjgardner.bsky.social
February 3, 2025 at 4:19 PM
Theta sweeps are population sequences in #gridcells and #placecells that, once per theta cycle, radiate outward from the animal’s location. In baseline conditions, they alternate rigidly left-right around the head axis, generating broad, forward-oriented sampling of nearby #space. (2/6) 🧠🧹
January 28, 2026 at 10:03 AM
Theta sweeps are population sequences in #gridcells and #placecells that, once per theta cycle, radiate outward from the animal’s location. In baseline conditions, they alternate rigidly left-right around the head axis, generating broad, forward-oriented sampling of nearby #space. (2/6) 🧠🧹
Its further based only on gridcells that have relatively complete data, though it is true that I probably should have started it around ~1900 given larger spatial gaps before then. But even in the 1870s we had pretty good coverage in Berkeley Earth:
April 29, 2026 at 12:48 AM
Its further based only on gridcells that have relatively complete data, though it is true that I probably should have started it around ~1900 given larger spatial gaps before then. But even in the 1870s we had pretty good coverage in Berkeley Earth:
Sweeps are accompanied by, and aligned with, a similarly alternating directional signal in a discrete population of direction-tuned cells with putative connections to the #gridcells 🗺️
February 3, 2025 at 4:18 PM
Sweeps are accompanied by, and aligned with, a similarly alternating directional signal in a discrete population of direction-tuned cells with putative connections to the #gridcells 🗺️
Ready for the Wednesday morning session at #SfN25? ☕️🧠 Come by row QQ for nice chats and mind boggling discoveries on #gridcells and space, from a new generation of brilliant researchers at @kavlintnu.bsky.social 👇🧵
Still at SfN on the last day? During the morning session on the 19th, 8:00AM - 12:00PM, come check out our posters from the Moser, Zong, and Gonzalo Cogno groups in row QQ ('Grid cells and spatially modulated cells'). Ephys, imaging, remapping, development, sweeps and more! 🧠
Detailed thread below 👇
Detailed thread below 👇
November 18, 2025 at 11:37 PM
Ready for the Wednesday morning session at #SfN25? ☕️🧠 Come by row QQ for nice chats and mind boggling discoveries on #gridcells and space, from a new generation of brilliant researchers at @kavlintnu.bsky.social 👇🧵
This is using a 3-level grid approach: Bricks of 8x8x8 voxels are indexed by cells of a grid; 4x4x4 gridcells are represented by a single bit in the 'topLevelGrid' for fast empty space skipping.
June 13, 2025 at 3:17 PM
This is using a 3-level grid approach: Bricks of 8x8x8 voxels are indexed by cells of a grid; 4x4x4 gridcells are represented by a single bit in the 'topLevelGrid' for fast empty space skipping.
#Gridcells generate rhythmic theta sweeps 🧹 across the brain’s internal map. We show these #sweeps are not rigid - they retune from moment to moment according to behavioral demands. They can narrow and lock onto prey, reverse during backward movement, and persist even during REM sleep. 🧵2/8
August 6, 2026 at 9:23 PM
#Gridcells generate rhythmic theta sweeps 🧹 across the brain’s internal map. We show these #sweeps are not rigid - they retune from moment to moment according to behavioral demands. They can narrow and lock onto prey, reverse during backward movement, and persist even during REM sleep. 🧵2/8
Finally out: #ThetaSweeps in the #entorhinal-#hippocampal #navigation circuit. In #rats 🧭🐀, these #theta-locked sweeps are not fixed scanning patterns, but can be rapidly redirected toward #behaviorally relevant locations. …
#Neuroscience #Hippocampus #GridCells #PlaceCells
#Neuroscience #Hippocampus #GridCells #PlaceCells
Out now in @science.org : How does the brain rapidly scan space to guide navigation? We found that the brain’s internal map is continuously retuned from moment to moment, focusing neural activity on what matters most.
🧵1/8
👉
www.science.org/doi/10.1126/...
🧵1/8
👉
www.science.org/doi/10.1126/...
Adaptive modulation of theta sweeps in the brain’s navigation circuit
Efficient navigation requires prioritizing information from behaviorally relevant locations. In rats, such selective sampling may arise from theta-paced sweeps in grid and place cell populations, whic...
www.science.org
August 6, 2026 at 9:32 PM
Finally out: #ThetaSweeps in the #entorhinal-#hippocampal #navigation circuit. In #rats 🧭🐀, these #theta-locked sweeps are not fixed scanning patterns, but can be rapidly redirected toward #behaviorally relevant locations. …
#Neuroscience #Hippocampus #GridCells #PlaceCells
#Neuroscience #Hippocampus #GridCells #PlaceCells
April 28, 2025 at 10:37 PM
#Gridcells generate rhythmic theta sweeps 🧹 across the brain’s internal map. We show these #sweeps are not rigid - they retune from moment to moment according to behavioral demands. They can narrow and lock onto prey, reverse during backward movement, and persist even during REM sleep. 🧵2/8
August 6, 2026 at 6:02 PM
#Gridcells generate rhythmic theta sweeps 🧹 across the brain’s internal map. We show these #sweeps are not rigid - they retune from moment to moment according to behavioral demands. They can narrow and lock onto prey, reverse during backward movement, and persist even during REM sleep. 🧵2/8
#29 from my Women in STEM series: May-Britt Moser
#WomeninSTEM
#academicsky
#neurobiology #gridcells #neuroscience
#NoblePrize
#WomeninSTEM
#academicsky
#neurobiology #gridcells #neuroscience
#NoblePrize
March 2, 2025 at 2:22 AM
#29 from my Women in STEM series: May-Britt Moser
#WomeninSTEM
#academicsky
#neurobiology #gridcells #neuroscience
#NoblePrize
#WomeninSTEM
#academicsky
#neurobiology #gridcells #neuroscience
#NoblePrize
We are thrilled to share that Dr. Jose A. Fernandez-Leon Fellenz has received an #IBRORisingStars #Award!
It is a remarkable achievement for our lab, given the highly competitive nature of the award.
#neuroscience #IBRO #IBRORisingStars #RisingStars #IBROinLatAm #UNICEN
#brain #gridcells
It is a remarkable achievement for our lab, given the highly competitive nature of the award.
#neuroscience #IBRO #IBRORisingStars #RisingStars #IBROinLatAm #UNICEN
#brain #gridcells
June 20, 2025 at 12:58 PM
We are thrilled to share that Dr. Jose A. Fernandez-Leon Fellenz has received an #IBRORisingStars #Award!
It is a remarkable achievement for our lab, given the highly competitive nature of the award.
#neuroscience #IBRO #IBRORisingStars #RisingStars #IBROinLatAm #UNICEN
#brain #gridcells
It is a remarkable achievement for our lab, given the highly competitive nature of the award.
#neuroscience #IBRO #IBRORisingStars #RisingStars #IBROinLatAm #UNICEN
#brain #gridcells
seems like the availability of compute steers research methods. brute force parameter explosion on tiny gridcells in tiny timesteps isn't the only way to understand things. It looks like it optimizes for better prediction at the expense of understanding, theory, reproducibility, and scrutiny.
August 1, 2026 at 4:57 PM
seems like the availability of compute steers research methods. brute force parameter explosion on tiny gridcells in tiny timesteps isn't the only way to understand things. It looks like it optimizes for better prediction at the expense of understanding, theory, reproducibility, and scrutiny.
Our team wanted to know whether patterning in climate events is associated with households receiving remittances, suggesting that households are using the traditional strategy of sharing resources across space. We looked at publicly available climate and household data from six African countries. 4/
August 6, 2026 at 4:23 PM
Our team wanted to know whether patterning in climate events is associated with households receiving remittances, suggesting that households are using the traditional strategy of sharing resources across space. We looked at publicly available climate and household data from six African countries. 4/
… A fascinating view of #ThetaSweeps as an attention-like mechanism for querying #CognitiveMaps in real time.
#Neuroscience 🧪 #Hippocampus #GridCells #PlaceCells #Navigation
#Neuroscience 🧪 #Hippocampus #GridCells #PlaceCells #Navigation
August 6, 2026 at 9:35 PM
… A fascinating view of #ThetaSweeps as an attention-like mechanism for querying #CognitiveMaps in real time.
#Neuroscience 🧪 #Hippocampus #GridCells #PlaceCells #Navigation
#Neuroscience 🧪 #Hippocampus #GridCells #PlaceCells #Navigation
Full preprint:
doi.org/10.5281/zeno...
“Affective Tagging as Metric Deformation in Cognitive Maps: A Variational Model”
Emotional tag weight changes node energy, effective distance, and associative trajectories.
#GridCells #CognitiveMaps #AffectiveTagging #TheoreticalNeuroscience
doi.org/10.5281/zeno...
“Affective Tagging as Metric Deformation in Cognitive Maps: A Variational Model”
Emotional tag weight changes node energy, effective distance, and associative trajectories.
#GridCells #CognitiveMaps #AffectiveTagging #TheoreticalNeuroscience
July 24, 2026 at 7:11 PM
Full preprint:
doi.org/10.5281/zeno...
“Affective Tagging as Metric Deformation in Cognitive Maps: A Variational Model”
Emotional tag weight changes node energy, effective distance, and associative trajectories.
#GridCells #CognitiveMaps #AffectiveTagging #TheoreticalNeuroscience
doi.org/10.5281/zeno...
“Affective Tagging as Metric Deformation in Cognitive Maps: A Variational Model”
Emotional tag weight changes node energy, effective distance, and associative trajectories.
#GridCells #CognitiveMaps #AffectiveTagging #TheoreticalNeuroscience
Theta sweeps are population sequences in #gridcells and #placecells that, once per theta cycle, radiate outward from the animal’s location. In baseline conditions, they alternate rigidly left-right around the head axis, generating broad, forward-oriented sampling of nearby #space. (2/6) 🧠🧹
January 28, 2026 at 9:50 AM
Theta sweeps are population sequences in #gridcells and #placecells that, once per theta cycle, radiate outward from the animal’s location. In baseline conditions, they alternate rigidly left-right around the head axis, generating broad, forward-oriented sampling of nearby #space. (2/6) 🧠🧹
CellWithNeighborsクラスは近傍のセルを認識します。GridCellsクラスはセルの二次元配列を管理し、GridCellsFactoryクラスは難易度に応じた盤面を生成します。
また、バリデーションの実装方法やテストの容易さについても触れられ、実践を通じた学びの重要性が強調されています。最後に、エンジニア向けの情報共有コミュニティ「Zenncafe日比谷」でのLT大会の開催が告知されています。 (2/2)
また、バリデーションの実装方法やテストの容易さについても触れられ、実践を通じた学びの重要性が強調されています。最後に、エンジニア向けの情報共有コミュニティ「Zenncafe日比谷」でのLT大会の開催が告知されています。 (2/2)
February 10, 2025 at 4:03 PM
CellWithNeighborsクラスは近傍のセルを認識します。GridCellsクラスはセルの二次元配列を管理し、GridCellsFactoryクラスは難易度に応じた盤面を生成します。
また、バリデーションの実装方法やテストの容易さについても触れられ、実践を通じた学びの重要性が強調されています。最後に、エンジニア向けの情報共有コミュニティ「Zenncafe日比谷」でのLT大会の開催が告知されています。 (2/2)
また、バリデーションの実装方法やテストの容易さについても触れられ、実践を通じた学びの重要性が強調されています。最後に、エンジニア向けの情報共有コミュニティ「Zenncafe日比谷」でのLT大会の開催が告知されています。 (2/2)
Yeah. It's a concern, but I wouldn't rate it as a big one when calculating the global mean. HadCRUT handles that kind of situation nicely by assigning appropriate uncertainties to all gridcells. Correlated errors from the individual ships are also accounted for.
September 6, 2024 at 8:41 AM
Yeah. It's a concern, but I wouldn't rate it as a big one when calculating the global mean. HadCRUT handles that kind of situation nicely by assigning appropriate uncertainties to all gridcells. Correlated errors from the individual ships are also accounted for.
今日のZennトレンド
マインスイーパでオブジェクト指向の設計を学んだ
この記事では、オブジェクト指向の学習に苦労した筆者が、マインスイーパを題材に設計を通じてオブジェクト指向の理解を深めた過程を解説しています。
単一責務の原則に基づき、Cellクラス、CellWithNeighborsクラス、GridCellsクラスを設計することで、疎結合で変更容易性の高いコードを実現しています。
特に、責務の分離と委譲によってコードの複雑さを軽減し、再利用性を高めている点が強調されています。
マインスイーパでオブジェクト指向の設計を学んだ
この記事では、オブジェクト指向の学習に苦労した筆者が、マインスイーパを題材に設計を通じてオブジェクト指向の理解を深めた過程を解説しています。
単一責務の原則に基づき、Cellクラス、CellWithNeighborsクラス、GridCellsクラスを設計することで、疎結合で変更容易性の高いコードを実現しています。
特に、責務の分離と委譲によってコードの複雑さを軽減し、再利用性を高めている点が強調されています。
マインスイーパでオブジェクト指向の設計を学んだ
はじめにオブジェクト指向の学び方について悩んだことはありませんか？私は設計の技術書を読んでもイマイチ腹に落ちない感覚を私は何度も味わってきました。本記事では、「マインスイーパ」を題材としてオブジェクト指向の設計をします。私はこの設計を通じてオブジェクト指向がチョットワカルになったので是非最後まで読んでいただけると嬉しいです。 対象読者オブジェクト指向を学びたい方ソフトウェア設計の技術書を1冊読ん
zenn.dev
February 10, 2025 at 9:17 PM
今日のZennトレンド
マインスイーパでオブジェクト指向の設計を学んだ
この記事では、オブジェクト指向の学習に苦労した筆者が、マインスイーパを題材に設計を通じてオブジェクト指向の理解を深めた過程を解説しています。
単一責務の原則に基づき、Cellクラス、CellWithNeighborsクラス、GridCellsクラスを設計することで、疎結合で変更容易性の高いコードを実現しています。
特に、責務の分離と委譲によってコードの複雑さを軽減し、再利用性を高めている点が強調されています。
マインスイーパでオブジェクト指向の設計を学んだ
この記事では、オブジェクト指向の学習に苦労した筆者が、マインスイーパを題材に設計を通じてオブジェクト指向の理解を深めた過程を解説しています。
単一責務の原則に基づき、Cellクラス、CellWithNeighborsクラス、GridCellsクラスを設計することで、疎結合で変更容易性の高いコードを実現しています。
特に、責務の分離と委譲によってコードの複雑さを軽減し、再利用性を高めている点が強調されています。