New research in eLife challenges some long-held ideas about place cells and grid cells and suggests a powerful border-to-place cell pathway for navigation.
Check it out: doi.org/10.7554/eLif...
#Neuroskyence #CompNeuro #AI #PlaceCells #CognitiveMaps
Check it out: doi.org/10.7554/eLif...
#Neuroskyence #CompNeuro #AI #PlaceCells #CognitiveMaps
Learning place cells and remapping by decoding the cognitive map
Border cells are sufficient to generate place cells and remapping during path integration in artificial neural networks, challenging the role of grid cells for spatial navigation.
doi.org
August 14, 2025 at 8:47 AM
New research in eLife challenges some long-held ideas about place cells and grid cells and suggests a powerful border-to-place cell pathway for navigation.
Check it out: doi.org/10.7554/eLif...
#Neuroskyence #CompNeuro #AI #PlaceCells #CognitiveMaps
Check it out: doi.org/10.7554/eLif...
#Neuroskyence #CompNeuro #AI #PlaceCells #CognitiveMaps
A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. 🧠🗺️ Out now in @pnas.org www.pnas.org/doi/10.1073/...
Place cells in CA1 lack topographical organization of firing locations | PNAS
Topography is a well-described and well-known concept for cortical organization in
primary sensory and motor cortices of mammalian brains. Similar ...
www.pnas.org
February 19, 2026 at 11:53 AM
A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. 🧠🗺️ Out now in @pnas.org www.pnas.org/doi/10.1073/...
Theta sweeps are population sequences in #gridcells and #placecells that, once per theta cycle, radiate outward from the animal’s location. In baseline conditions, they alternate rigidly left-right around the head axis, generating broad, forward-oriented sampling of nearby #space. (2/6) 🧠🧹
January 28, 2026 at 10:03 AM
Theta sweeps are population sequences in #gridcells and #placecells that, once per theta cycle, radiate outward from the animal’s location. In baseline conditions, they alternate rigidly left-right around the head axis, generating broad, forward-oriented sampling of nearby #space. (2/6) 🧠🧹
Theta sweeps are population sequences in #gridcells and #placecells that, once per theta cycle, radiate outward from the animal’s location. In baseline conditions, they alternate rigidly left-right around the head axis, generating broad, forward-oriented sampling of nearby #space. (2/6) 🧠🧹
January 28, 2026 at 9:50 AM
Theta sweeps are population sequences in #gridcells and #placecells that, once per theta cycle, radiate outward from the animal’s location. In baseline conditions, they alternate rigidly left-right around the head axis, generating broad, forward-oriented sampling of nearby #space. (2/6) 🧠🧹
5/5 Big thanks to the team and collaborators @clykken.bsky.social @beneuroscience.bsky.social @anagelhus.bsky.social @jocarpenter.bsky.social @matteoguardamagna.bsky.social @m-bmoser.bsky.social @kavlintnu.bsky.social
#Neuroscience #GridCells #PlaceCells #EpisodicMemory #Neuropixels #KiloNeurons
#Neuroscience #GridCells #PlaceCells #EpisodicMemory #Neuropixels #KiloNeurons
September 25, 2025 at 4:06 AM
So happy to release this to the world!! A big one that's been cooking for years.
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇
1/5 How does the brain turn the low-dimensional, universal grid cell metric into the rich, diverse codes needed for memory in hippocampal place cells? 🧵
Preprint link 👇
www.biorxiv.org/content/10.1...
Preprint link 👇
www.biorxiv.org/content/10.1...
Functional independence of entorhinal grid cell modules enables remapping in hippocampal place cells
A systems-level understanding of cortical computation requires insight into how neural codes are transformed across distinct brain circuits. In the mammalian cortex, one of the few systems where such ...
www.biorxiv.org
September 25, 2025 at 4:26 AM
So happy to release this to the world!! A big one that's been cooking for years.
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇
1/6
Do neighboring #PlaceCells in #Hippocampus CA1 map neighboring locations in space? 🧠🗺️
Is there micro-scale spatial topography in the hippocampus?
See our latest paper from @kavlintnu now out in @pnas.org www.pnas.org/doi/10.1073/...
Do neighboring #PlaceCells in #Hippocampus CA1 map neighboring locations in space? 🧠🗺️
Is there micro-scale spatial topography in the hippocampus?
See our latest paper from @kavlintnu now out in @pnas.org www.pnas.org/doi/10.1073/...
February 20, 2026 at 12:17 PM
1/6
Do neighboring #PlaceCells in #Hippocampus CA1 map neighboring locations in space? 🧠🗺️
Is there micro-scale spatial topography in the hippocampus?
See our latest paper from @kavlintnu now out in @pnas.org www.pnas.org/doi/10.1073/...
Do neighboring #PlaceCells in #Hippocampus CA1 map neighboring locations in space? 🧠🗺️
Is there micro-scale spatial topography in the hippocampus?
See our latest paper from @kavlintnu now out in @pnas.org www.pnas.org/doi/10.1073/...
🚨New Paper out in #PNAS: "Spatial coding in the #hippocampus and #hyperpallium of flying #owls"🦉 Very cool study using wireless neural logger in freeflying birds! #navigation #placecells @GutfreundS @AyeletSarel @derdikman @GutfreundYoram @PNASNews @theNASciences
January 18, 2025 at 2:41 AM
🚨New Paper out in #PNAS: "Spatial coding in the #hippocampus and #hyperpallium of flying #owls"🦉 Very cool study using wireless neural logger in freeflying birds! #navigation #placecells @GutfreundS @AyeletSarel @derdikman @GutfreundYoram @PNASNews @theNASciences
More strangeness: about a third of place cells exhibited repeating firing fields on each ridge.
Even though the ridges were in completely different parts of the room, the brain seemed to map them similarly based on their shape.
#PlaceCells #TerrainCells
10/
Even though the ridges were in completely different parts of the room, the brain seemed to map them similarly based on their shape.
#PlaceCells #TerrainCells
10/
June 5, 2026 at 1:07 PM
More strangeness: about a third of place cells exhibited repeating firing fields on each ridge.
Even though the ridges were in completely different parts of the room, the brain seemed to map them similarly based on their shape.
#PlaceCells #TerrainCells
10/
Even though the ridges were in completely different parts of the room, the brain seemed to map them similarly based on their shape.
#PlaceCells #TerrainCells
10/
These "place cells" underlie an internal map of the world around you.
They are mostly found in a really cool brain region called the hippocampus 🧠
Video showing the activity of a single place cell 👇️️️ www.youtube.com/watch?v=ZNEE...
#placecells #hippocampus
4/
They are mostly found in a really cool brain region called the hippocampus 🧠
Video showing the activity of a single place cell 👇️️️ www.youtube.com/watch?v=ZNEE...
#placecells #hippocampus
4/
Place cell (rat hippocampus CA1) activity recorded over 50 minutes of foraging
YouTube video by Roddy Grieves
www.youtube.com
June 5, 2026 at 1:07 PM
These "place cells" underlie an internal map of the world around you.
They are mostly found in a really cool brain region called the hippocampus 🧠
Video showing the activity of a single place cell 👇️️️ www.youtube.com/watch?v=ZNEE...
#placecells #hippocampus
4/
They are mostly found in a really cool brain region called the hippocampus 🧠
Video showing the activity of a single place cell 👇️️️ www.youtube.com/watch?v=ZNEE...
#placecells #hippocampus
4/
What exactly are "place cells"? ⁉️
When you walk around your kitchen, a specific neuron activates (fires action potentials) only when you stand next to the fridge.
Move over to the sink, and a completely different neuron activates.
#placecells #hippocampus
3/
When you walk around your kitchen, a specific neuron activates (fires action potentials) only when you stand next to the fridge.
Move over to the sink, and a completely different neuron activates.
#placecells #hippocampus
3/
June 5, 2026 at 1:07 PM
What exactly are "place cells"? ⁉️
When you walk around your kitchen, a specific neuron activates (fires action potentials) only when you stand next to the fridge.
Move over to the sink, and a completely different neuron activates.
#placecells #hippocampus
3/
When you walk around your kitchen, a specific neuron activates (fires action potentials) only when you stand next to the fridge.
Move over to the sink, and a completely different neuron activates.
#placecells #hippocampus
3/
To find out, we recorded from hippocampal place cells, which are thought to underlie the brain's internal map, while rats foraged in a large (3x1.5 meters!) custom-built 3D "Hillscape" featuring three sinusoidal ridges.
⛰️ ⛰️ ⛰️
#placecells #hippocampus
2/
⛰️ ⛰️ ⛰️
#placecells #hippocampus
2/
June 5, 2026 at 1:07 PM
To find out, we recorded from hippocampal place cells, which are thought to underlie the brain's internal map, while rats foraged in a large (3x1.5 meters!) custom-built 3D "Hillscape" featuring three sinusoidal ridges.
⛰️ ⛰️ ⛰️
#placecells #hippocampus
2/
⛰️ ⛰️ ⛰️
#placecells #hippocampus
2/
Nice paper from Fuentealba et al. (2025) looking at the involvement of hippocampus in the emulation of conspecifics: www.sciencedirect.com/science/arti...
#Neuroscience #Hippocampus #PlaceCells #SpatialLearning
#Neuroscience #Hippocampus #PlaceCells #SpatialLearning
Emulation as a behavioral strategy underlying spatial observational learning in rats
Humans and several non-human species have shown the ability to learn by observing an experimented conspecific. A basic form of this learning is spatia…
www.sciencedirect.com
October 13, 2025 at 10:25 AM
Nice paper from Fuentealba et al. (2025) looking at the involvement of hippocampus in the emulation of conspecifics: www.sciencedirect.com/science/arti...
#Neuroscience #Hippocampus #PlaceCells #SpatialLearning
#Neuroscience #Hippocampus #PlaceCells #SpatialLearning
I’m excited to share my final co-first author paper from my postdoc in Dan Dombeck's lab!
We explored how behavior, senses, and neurons influence how much information in the brain changes over time.
www.nature.com/articles/s41...
#science #research #neuroscience #hippocampus #placecells
We explored how behavior, senses, and neurons influence how much information in the brain changes over time.
www.nature.com/articles/s41...
#science #research #neuroscience #hippocampus #placecells
Hippocampal representations drift in stable multisensory environments - Nature
Tracking of individual place cells in mouse CA1 shows that representational drift is not influenced by changes in environment or behaviour, and is lower for more excitable place cells.
www.nature.com
July 23, 2025 at 4:12 PM
I’m excited to share my final co-first author paper from my postdoc in Dan Dombeck's lab!
We explored how behavior, senses, and neurons influence how much information in the brain changes over time.
www.nature.com/articles/s41...
#science #research #neuroscience #hippocampus #placecells
We explored how behavior, senses, and neurons influence how much information in the brain changes over time.
www.nature.com/articles/s41...
#science #research #neuroscience #hippocampus #placecells
… A fascinating view of #ThetaSweeps as an attention-like mechanism for querying #CognitiveMaps in real time.
#Neuroscience 🧪 #Hippocampus #GridCells #PlaceCells #Navigation
#Neuroscience 🧪 #Hippocampus #GridCells #PlaceCells #Navigation
August 6, 2026 at 9:35 PM
… A fascinating view of #ThetaSweeps as an attention-like mechanism for querying #CognitiveMaps in real time.
#Neuroscience 🧪 #Hippocampus #GridCells #PlaceCells #Navigation
#Neuroscience 🧪 #Hippocampus #GridCells #PlaceCells #Navigation
Finally out: #ThetaSweeps in the #entorhinal-#hippocampal #navigation circuit. In #rats 🧭🐀, these #theta-locked sweeps are not fixed scanning patterns, but can be rapidly redirected toward #behaviorally relevant locations. …
#Neuroscience #Hippocampus #GridCells #PlaceCells
#Neuroscience #Hippocampus #GridCells #PlaceCells
Out now in @science.org : How does the brain rapidly scan space to guide navigation? We found that the brain’s internal map is continuously retuned from moment to moment, focusing neural activity on what matters most.
🧵1/8
👉
www.science.org/doi/10.1126/...
🧵1/8
👉
www.science.org/doi/10.1126/...
Adaptive modulation of theta sweeps in the brain’s navigation circuit
Efficient navigation requires prioritizing information from behaviorally relevant locations. In rats, such selective sampling may arise from theta-paced sweeps in grid and place cell populations, whic...
www.science.org
August 6, 2026 at 9:32 PM
Finally out: #ThetaSweeps in the #entorhinal-#hippocampal #navigation circuit. In #rats 🧭🐀, these #theta-locked sweeps are not fixed scanning patterns, but can be rapidly redirected toward #behaviorally relevant locations. …
#Neuroscience #Hippocampus #GridCells #PlaceCells
#Neuroscience #Hippocampus #GridCells #PlaceCells
The paper suggests that the #hippocampal map is shaped by terrain geometry itself, not only by where the animal runs. Slopes, ridges & surface contours may act as spatial structure for #PlaceCells. Read the full 🧵 on 🐘: https://fediscience.org/@rmgrieves/116692850991318267
#SpatialNavigation
#SpatialNavigation
Roddy Grieves (@rmgrieves@fediscience.org)
Attached: 1 image
Ever wonder how your brain navigates the real world? 🧠
Most laboratory neuroscience studies look at spatial navigation in flat, 2D mazes.
But the real world is hilly, irregular,...
fediscience.org
June 4, 2026 at 7:41 PM
The paper suggests that the #hippocampal map is shaped by terrain geometry itself, not only by where the animal runs. Slopes, ridges & surface contours may act as spatial structure for #PlaceCells. Read the full 🧵 on 🐘: https://fediscience.org/@rmgrieves/116692850991318267
#SpatialNavigation
#SpatialNavigation
New paper by Grieves, Duvelle & Taube: Rat #hippocampal #PlaceCells map terrain geometry independently of #behavior. On ridged “hillscape” terrain, #PlaceFields remapped, aligned with terrain contours & repeated across similar #topography:
📄 https://doi.org/10.1126/sciadv.adz9893
#Neuroscience 🧪
📄 https://doi.org/10.1126/sciadv.adz9893
#Neuroscience 🧪
June 4, 2026 at 7:31 PM
New paper by Grieves, Duvelle & Taube: Rat #hippocampal #PlaceCells map terrain geometry independently of #behavior. On ridged “hillscape” terrain, #PlaceFields remapped, aligned with terrain contours & repeated across similar #topography:
📄 https://doi.org/10.1126/sciadv.adz9893
#Neuroscience 🧪
📄 https://doi.org/10.1126/sciadv.adz9893
#Neuroscience 🧪
In the latest #KempnerInstitute talk, @behrenstimb.bsky.social of @ox.ac.uk explains how a class of ‘goal-progress' cells in mouse prefrontal cortex serves as a schema for mapping behavior. Watch the talk: youtu.be/JGwyHXigSQc #PFC #memory #placecells #brain
A Cellular Basis For Mapping Behavioural Structure with Tim Behrens
YouTube video by Kempner Institute at Harvard University
youtu.be
March 23, 2025 at 7:02 PM
In the latest #KempnerInstitute talk, @behrenstimb.bsky.social of @ox.ac.uk explains how a class of ‘goal-progress' cells in mouse prefrontal cortex serves as a schema for mapping behavior. Watch the talk: youtu.be/JGwyHXigSQc #PFC #memory #placecells #brain
Do #PlaceCells that sit next to each other also represent nearby places in the world? 🧠🤝🗺️
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
February 19, 2026 at 11:59 AM
Do #PlaceCells that sit next to each other also represent nearby places in the world? 🧠🤝🗺️
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...