Yesterday, we hosted another installment of HCR™ webinars!
Thank you to our speakers, Xiqian Jiang and Lun Wang from Stanford, for sharing how TRU-FACT integrates #HCRtechnology with functional imaging and connectivity data to link cellular activity, molecular identity, and projection targets.
Thank you to our speakers, Xiqian Jiang and Lun Wang from Stanford, for sharing how TRU-FACT integrates #HCRtechnology with functional imaging and connectivity data to link cellular activity, molecular identity, and projection targets.
September 24, 2026 at 4:04 PM
Yesterday, we hosted another installment of HCR™ webinars!
Thank you to our speakers, Xiqian Jiang and Lun Wang from Stanford, for sharing how TRU-FACT integrates #HCRtechnology with functional imaging and connectivity data to link cellular activity, molecular identity, and projection targets.
Thank you to our speakers, Xiqian Jiang and Lun Wang from Stanford, for sharing how TRU-FACT integrates #HCRtechnology with functional imaging and connectivity data to link cellular activity, molecular identity, and projection targets.
We’re heading to NSH this weekend!
Stop by Booth #620 to connect with our team and join us for our workshop, “Translating Spatial RNA Biomarkers into Point-of-Care Lateral Flow Assays,” where we’ll highlight how #HCRtechnology can be adapted for lateral flow detection.
🗓️ Sept. 29
🕤 9:15–10:15 AM
Stop by Booth #620 to connect with our team and join us for our workshop, “Translating Spatial RNA Biomarkers into Point-of-Care Lateral Flow Assays,” where we’ll highlight how #HCRtechnology can be adapted for lateral flow detection.
🗓️ Sept. 29
🕤 9:15–10:15 AM
September 23, 2026 at 4:47 PM
We’re heading to NSH this weekend!
Stop by Booth #620 to connect with our team and join us for our workshop, “Translating Spatial RNA Biomarkers into Point-of-Care Lateral Flow Assays,” where we’ll highlight how #HCRtechnology can be adapted for lateral flow detection.
🗓️ Sept. 29
🕤 9:15–10:15 AM
Stop by Booth #620 to connect with our team and join us for our workshop, “Translating Spatial RNA Biomarkers into Point-of-Care Lateral Flow Assays,” where we’ll highlight how #HCRtechnology can be adapted for lateral flow detection.
🗓️ Sept. 29
🕤 9:15–10:15 AM
#onlywithHCR: LaBelle et al. reveal that cell–cell collisions are drivers of the dispersal of endodermal cells in zebrafish embryos. With #HCRtechnology, they observed epha2a expression, finding that endodermal cells undergo RhoA-dependent, active repulsion-type CIL.
Read more: tinyurl.com/mrx934sc
Read more: tinyurl.com/mrx934sc
December 12, 2025 at 6:50 PM
#onlywithHCR: LaBelle et al. reveal that cell–cell collisions are drivers of the dispersal of endodermal cells in zebrafish embryos. With #HCRtechnology, they observed epha2a expression, finding that endodermal cells undergo RhoA-dependent, active repulsion-type CIL.
Read more: tinyurl.com/mrx934sc
Read more: tinyurl.com/mrx934sc
#onlywithHCR: With #HCRtechnology, Witch et al. revealed that salamander brain comparisons point to the DVR and neocortex evolving through convergence, while the mammalian olfactory-entorhinal-hippocampal circuit may trace back to ancestral origins.
Read more: tinyurl.com/4bwm599u
Read more: tinyurl.com/4bwm599u
August 22, 2025 at 5:00 PM
#onlywithHCR: With #HCRtechnology, Witch et al. revealed that salamander brain comparisons point to the DVR and neocortex evolving through convergence, while the mammalian olfactory-entorhinal-hippocampal circuit may trace back to ancestral origins.
Read more: tinyurl.com/4bwm599u
Read more: tinyurl.com/4bwm599u
A study from Jimenez et al. brings high-res molecular readouts to Paroedura picta.
Using #HCRtechnology, the team mapped gene expression in the embryonic gecko brain, enabling clear mRNA visualization in a system with limited species-specific antibody options.
Read more: tinyurl.com/5dnwkm3h
Using #HCRtechnology, the team mapped gene expression in the embryonic gecko brain, enabling clear mRNA visualization in a system with limited species-specific antibody options.
Read more: tinyurl.com/5dnwkm3h
March 3, 2026 at 5:35 PM
A study from Jimenez et al. brings high-res molecular readouts to Paroedura picta.
Using #HCRtechnology, the team mapped gene expression in the embryonic gecko brain, enabling clear mRNA visualization in a system with limited species-specific antibody options.
Read more: tinyurl.com/5dnwkm3h
Using #HCRtechnology, the team mapped gene expression in the embryonic gecko brain, enabling clear mRNA visualization in a system with limited species-specific antibody options.
Read more: tinyurl.com/5dnwkm3h
We’re looking forward to attending Euro Evo Devo!
If you’ll be there, stop by and meet Joyce Yoo and Michelle Saylor from the MI team. We’d love to hear more about your research and talk about how #HCRtechnology could support your next set of experiments.
Schedule a meeting: tinyurl.com/3a9fpzdv
If you’ll be there, stop by and meet Joyce Yoo and Michelle Saylor from the MI team. We’d love to hear more about your research and talk about how #HCRtechnology could support your next set of experiments.
Schedule a meeting: tinyurl.com/3a9fpzdv
June 4, 2026 at 4:11 PM
We’re looking forward to attending Euro Evo Devo!
If you’ll be there, stop by and meet Joyce Yoo and Michelle Saylor from the MI team. We’d love to hear more about your research and talk about how #HCRtechnology could support your next set of experiments.
Schedule a meeting: tinyurl.com/3a9fpzdv
If you’ll be there, stop by and meet Joyce Yoo and Michelle Saylor from the MI team. We’d love to hear more about your research and talk about how #HCRtechnology could support your next set of experiments.
Schedule a meeting: tinyurl.com/3a9fpzdv
One of the most rewarding parts of being on the road is hearing how our users are putting #HCRtechnology to work in their own labs.
From the Euro Evo Devo meeting to our HCR™ Office Hours, we loved connecting with researchers exploring a wide range of questions, organisms, and applications.
From the Euro Evo Devo meeting to our HCR™ Office Hours, we loved connecting with researchers exploring a wide range of questions, organisms, and applications.
June 16, 2026 at 4:08 PM
One of the most rewarding parts of being on the road is hearing how our users are putting #HCRtechnology to work in their own labs.
From the Euro Evo Devo meeting to our HCR™ Office Hours, we loved connecting with researchers exploring a wide range of questions, organisms, and applications.
From the Euro Evo Devo meeting to our HCR™ Office Hours, we loved connecting with researchers exploring a wide range of questions, organisms, and applications.
SDB is one of our favorite places to catch up with the dev bio community, and it’s always fun to see how #HCRtechnology is being used across both model and non-model organisms. We’d love to hear what you’re working on and chat about how the HCR™ platform might fit!
📅 July 23–26
📍 Booth #5
📅 July 23–26
📍 Booth #5
July 9, 2026 at 5:25 PM
SDB is one of our favorite places to catch up with the dev bio community, and it’s always fun to see how #HCRtechnology is being used across both model and non-model organisms. We’d love to hear what you’re working on and chat about how the HCR™ platform might fit!
📅 July 23–26
📍 Booth #5
📅 July 23–26
📍 Booth #5
#onlywithHCR: Diaz Soria et al. used scRNA-seq with #HCRtechnology to build a cellular atlas of the mother sporocyst, spatially validating 6 major cell types and revealing key regulators of early parasite growth and snail-host interaction.
Read the full study @nature.com: tinyurl.com/bp7dbsjx
Read the full study @nature.com: tinyurl.com/bp7dbsjx
Single-cell transcriptomics of the human parasite Schistosoma mansoni first intra-molluscan stage reveals tentative tegumental and stem-cell regulators - Scientific Reports
Scientific Reports - Single-cell transcriptomics of the human parasite Schistosoma mansoni first intra-molluscan stage reveals tentative tegumental and stem-cell regulators
tinyurl.com
December 5, 2025 at 6:27 PM
#onlywithHCR: Diaz Soria et al. used scRNA-seq with #HCRtechnology to build a cellular atlas of the mother sporocyst, spatially validating 6 major cell types and revealing key regulators of early parasite growth and snail-host interaction.
Read the full study @nature.com: tinyurl.com/bp7dbsjx
Read the full study @nature.com: tinyurl.com/bp7dbsjx
What a fantastic time at the German Fish Meeting!
It’s always exciting to see #HCRtechnology used in such a wide range of model systems. This week, it was especially fun to hear about so many fish models, including zebrafish, cavefish, and more.
Next up for the MI team: NSH Convention!
It’s always exciting to see #HCRtechnology used in such a wide range of model systems. This week, it was especially fun to hear about so many fish models, including zebrafish, cavefish, and more.
Next up for the MI team: NSH Convention!
September 18, 2026 at 5:10 PM
What a fantastic time at the German Fish Meeting!
It’s always exciting to see #HCRtechnology used in such a wide range of model systems. This week, it was especially fun to hear about so many fish models, including zebrafish, cavefish, and more.
Next up for the MI team: NSH Convention!
It’s always exciting to see #HCRtechnology used in such a wide range of model systems. This week, it was especially fun to hear about so many fish models, including zebrafish, cavefish, and more.
Next up for the MI team: NSH Convention!
Lun Wang and Xiqian Jiang from Stanford are sharing an in-depth look at how TRU-FACT can match thousands of neurons across in vivo imaging and molecular profiling datasets, including those generated with #HCRtechnology.
🗓️ Wednesday, September 23
🕤 10:00 AM PT
Register here: tinyurl.com/45r6eza6
🗓️ Wednesday, September 23
🕤 10:00 AM PT
Register here: tinyurl.com/45r6eza6
September 17, 2026 at 4:06 PM
Lun Wang and Xiqian Jiang from Stanford are sharing an in-depth look at how TRU-FACT can match thousands of neurons across in vivo imaging and molecular profiling datasets, including those generated with #HCRtechnology.
🗓️ Wednesday, September 23
🕤 10:00 AM PT
Register here: tinyurl.com/45r6eza6
🗓️ Wednesday, September 23
🕤 10:00 AM PT
Register here: tinyurl.com/45r6eza6
Thank you to everyone who spent time with us at SDB!
It was a pleasure hearing about the developmental systems you’re working with and how #HCRtechnology supports your research.
If we missed you at SDB, reach out to us at info@molecularinstruments.com. We’d be happy to connect!
It was a pleasure hearing about the developmental systems you’re working with and how #HCRtechnology supports your research.
If we missed you at SDB, reach out to us at info@molecularinstruments.com. We’d be happy to connect!
July 28, 2026 at 5:03 PM
Thank you to everyone who spent time with us at SDB!
It was a pleasure hearing about the developmental systems you’re working with and how #HCRtechnology supports your research.
If we missed you at SDB, reach out to us at info@molecularinstruments.com. We’d be happy to connect!
It was a pleasure hearing about the developmental systems you’re working with and how #HCRtechnology supports your research.
If we missed you at SDB, reach out to us at info@molecularinstruments.com. We’d be happy to connect!
We’re excited to share that MI will be attending the Indica Labs HALO® User Group Meeting! If you’re in the Boston area, we would love to connect. Our team will be on-site to answer any questions you may have about adding #HCRtechnology to your workflows.
🗓️ May 12th
📍Le Méridien Boston Cambridge
🗓️ May 12th
📍Le Méridien Boston Cambridge
May 6, 2026 at 4:09 PM
We’re excited to share that MI will be attending the Indica Labs HALO® User Group Meeting! If you’re in the Boston area, we would love to connect. Our team will be on-site to answer any questions you may have about adding #HCRtechnology to your workflows.
🗓️ May 12th
📍Le Méridien Boston Cambridge
🗓️ May 12th
📍Le Méridien Boston Cambridge
At #AACR26, we’re sharing how the HCR™ platform is helping advance oncology research through flexible, multiplexed approaches. We're featuring several posters that highlight #HCRtechnology across multiplex IF, spatial biology, and tumor profiling.
Schedule a meeting with us: tinyurl.com/y662n5zz
Schedule a meeting with us: tinyurl.com/y662n5zz
April 15, 2026 at 5:01 PM
At #AACR26, we’re sharing how the HCR™ platform is helping advance oncology research through flexible, multiplexed approaches. We're featuring several posters that highlight #HCRtechnology across multiplex IF, spatial biology, and tumor profiling.
Schedule a meeting with us: tinyurl.com/y662n5zz
Schedule a meeting with us: tinyurl.com/y662n5zz
We were thrilled by the turnout for our webinar!
A special thank you to the Miller Lab for sharing their research on how #HCRtechnology can visualize gene expression in the developing kidney and study how genetic variants disrupt nephron development.
Watch the replay here: tinyurl.com/54eyp4ed
A special thank you to the Miller Lab for sharing their research on how #HCRtechnology can visualize gene expression in the developing kidney and study how genetic variants disrupt nephron development.
Watch the replay here: tinyurl.com/54eyp4ed
April 2, 2026 at 6:58 PM
We were thrilled by the turnout for our webinar!
A special thank you to the Miller Lab for sharing their research on how #HCRtechnology can visualize gene expression in the developing kidney and study how genetic variants disrupt nephron development.
Watch the replay here: tinyurl.com/54eyp4ed
A special thank you to the Miller Lab for sharing their research on how #HCRtechnology can visualize gene expression in the developing kidney and study how genetic variants disrupt nephron development.
Watch the replay here: tinyurl.com/54eyp4ed
Tune in on April 1 at 8:00 AM PT / 10:00 AM CT for a preview of never-before-shared images, and see how #HCRtechnology helps the Miller Lab investigate genes linked to CAKUT and better understand the mechanisms driving congenital kidney disease.
Register here: my.demio.com/ref/2ZwGxz9P...
Register here: my.demio.com/ref/2ZwGxz9P...
March 26, 2026 at 3:06 PM
Tune in on April 1 at 8:00 AM PT / 10:00 AM CT for a preview of never-before-shared images, and see how #HCRtechnology helps the Miller Lab investigate genes linked to CAKUT and better understand the mechanisms driving congenital kidney disease.
Register here: my.demio.com/ref/2ZwGxz9P...
Register here: my.demio.com/ref/2ZwGxz9P...
#onlywithHCR: Gillis et al. used #HCRtechnology to visualize gene expression during gill slit formation in skate embryos, revealing a precise sequence of epithelial interactions between the endoderm and ectoderm.
🔬 Read more: tinyurl.com/3mvj2wu2
🔬 Read more: tinyurl.com/3mvj2wu2
October 24, 2025 at 4:19 PM
#onlywithHCR: Gillis et al. used #HCRtechnology to visualize gene expression during gill slit formation in skate embryos, revealing a precise sequence of epithelial interactions between the endoderm and ectoderm.
🔬 Read more: tinyurl.com/3mvj2wu2
🔬 Read more: tinyurl.com/3mvj2wu2
#onlywithHCR: Bhandiwad et al. utilized #HCRtechnology to map the neural activity underlying tonic immobility. They found that this outlines a complete sensorimotor circuit, revealing how the brainstem circuit suppresses movement when facing threats.
Read more: tinyurl.com/4dcxhs38
Read more: tinyurl.com/4dcxhs38
September 26, 2025 at 5:27 PM
#onlywithHCR: Bhandiwad et al. utilized #HCRtechnology to map the neural activity underlying tonic immobility. They found that this outlines a complete sensorimotor circuit, revealing how the brainstem circuit suppresses movement when facing threats.
Read more: tinyurl.com/4dcxhs38
Read more: tinyurl.com/4dcxhs38
#onlywithHCR: Sun et al. uncovered a crucial role for Zic5 in Xenopus eye development. Using #HCRtechnology, they showed Zic5 expression in the RPE and NR at the optic vesicle stage, where it helps tune Hedgehog signaling to ensure proper eye development.
Read more: tinyurl.com/mrxru323
Read more: tinyurl.com/mrxru323
September 12, 2025 at 6:36 PM
#onlywithHCR: Sun et al. uncovered a crucial role for Zic5 in Xenopus eye development. Using #HCRtechnology, they showed Zic5 expression in the RPE and NR at the optic vesicle stage, where it helps tune Hedgehog signaling to ensure proper eye development.
Read more: tinyurl.com/mrxru323
Read more: tinyurl.com/mrxru323
#onlywithHCR: Busby et al. utilized #HCRtechnology to track gene expression during chicken somitogenesis. They revealed a stalled cell state linked to Hox genes, indicating that developmental timing is set intrinsically but can also be influenced by extrinsic cues.
Read more: tinyurl.com/pxs5jrcu
Read more: tinyurl.com/pxs5jrcu
September 5, 2025 at 5:30 PM
#onlywithHCR: Busby et al. utilized #HCRtechnology to track gene expression during chicken somitogenesis. They revealed a stalled cell state linked to Hox genes, indicating that developmental timing is set intrinsically but can also be influenced by extrinsic cues.
Read more: tinyurl.com/pxs5jrcu
Read more: tinyurl.com/pxs5jrcu
#onlywithHCR: Janesick et al. created an RNA-seq atlas of the chicken cochlea, revealing regenerative insights. Using #HCRtechnology to validate gene expression, they found tonotopic gradients along the cochlea, setting up the stage for comparative studies.
Read more: tinyurl.com/2t7zhfwn
Read more: tinyurl.com/2t7zhfwn
August 29, 2025 at 4:30 PM
#onlywithHCR: Janesick et al. created an RNA-seq atlas of the chicken cochlea, revealing regenerative insights. Using #HCRtechnology to validate gene expression, they found tonotopic gradients along the cochlea, setting up the stage for comparative studies.
Read more: tinyurl.com/2t7zhfwn
Read more: tinyurl.com/2t7zhfwn
#onlywithHCR: Treen et al. pinpointed two Prdm1 homologs as the earliest FGF-responsive genes. By combining #HCRtechnology with genetic and experimental manipulations, they found a sharp developmental transition between the 8- and 16-cell stages.
Read more: genesdev.cshlp.org/content/37/3...
Read more: genesdev.cshlp.org/content/37/3...
August 15, 2025 at 6:00 PM
#onlywithHCR: Treen et al. pinpointed two Prdm1 homologs as the earliest FGF-responsive genes. By combining #HCRtechnology with genetic and experimental manipulations, they found a sharp developmental transition between the 8- and 16-cell stages.
Read more: genesdev.cshlp.org/content/37/3...
Read more: genesdev.cshlp.org/content/37/3...
#onlywithHCR: Kim et al. dissected how human pyramidal neurons connect to inhibitory interneurons in a cell type-specific manner. Using #HCRtechnology to confirm cell types and gene expression, they discovered conserved synaptic motifs in human brain circuits.
Read more: tinyurl.com/4nrsm275
Read more: tinyurl.com/4nrsm275
August 8, 2025 at 5:00 PM
#onlywithHCR: Kim et al. dissected how human pyramidal neurons connect to inhibitory interneurons in a cell type-specific manner. Using #HCRtechnology to confirm cell types and gene expression, they discovered conserved synaptic motifs in human brain circuits.
Read more: tinyurl.com/4nrsm275
Read more: tinyurl.com/4nrsm275
#onlywithHCR: Lin et al. mapped ~500K nuclei across 19 CNS regions in marmoset to chart glial diversity.
With #HCRtechnology, they visualized key gene expression patterns in OLIG2+ cells, revealing transcriptional shifts in white matter glia within a 3D context.
Read more: tinyurl.com/bdfadjnr
With #HCRtechnology, they visualized key gene expression patterns in OLIG2+ cells, revealing transcriptional shifts in white matter glia within a 3D context.
Read more: tinyurl.com/bdfadjnr
August 1, 2025 at 5:00 PM
#onlywithHCR: Lin et al. mapped ~500K nuclei across 19 CNS regions in marmoset to chart glial diversity.
With #HCRtechnology, they visualized key gene expression patterns in OLIG2+ cells, revealing transcriptional shifts in white matter glia within a 3D context.
Read more: tinyurl.com/bdfadjnr
With #HCRtechnology, they visualized key gene expression patterns in OLIG2+ cells, revealing transcriptional shifts in white matter glia within a 3D context.
Read more: tinyurl.com/bdfadjnr
Join us for a Lunch & Learn at the Harvard Center for Biological Imaging! This session will feature a talk by Dr. Aneesh Acharya, who will share new and exciting updates on #HCRtechnology.
📍 16 Divinity Ave, BioLabs RM1080
🗓️ July 22nd, 2025 at 12:00 PM
📍 16 Divinity Ave, BioLabs RM1080
🗓️ July 22nd, 2025 at 12:00 PM
July 14, 2025 at 4:46 PM
Join us for a Lunch & Learn at the Harvard Center for Biological Imaging! This session will feature a talk by Dr. Aneesh Acharya, who will share new and exciting updates on #HCRtechnology.
📍 16 Divinity Ave, BioLabs RM1080
🗓️ July 22nd, 2025 at 12:00 PM
📍 16 Divinity Ave, BioLabs RM1080
🗓️ July 22nd, 2025 at 12:00 PM