#HumanRelevant
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safermedicines.org
Experimental methods that don’t use animals, like tissue chips and computational models, lead to the development of safer and more effective therapies and pharmaceuticals.

#betterscience #humanrelevant

utahnewsdispatch.com/2025/04/16/k...
Kudos to the FDA and EPA for planning to phase out animal testing • Utah News Dispatch
Commentary: The Food and Drug Administration and the Environmental Protection Agency say they will start backing off of animal testing.
utahnewsdispatch.com
April 19, 2025 at 7:52 AM
keintierversuch.bsky.social
30 Wochen #Einsamkeit im #Mäusekäfig? Solche #Tierversuche sind unnötig! Eine Studie mit 42.000 Menschen zeigt: Einsamkeit hinterlässt Spuren im Blut – eine Erkenntnis gewonnen ganz ohne #Tierleid. Wer den #Menschen verstehen will, muss auch am Menschen #forschen. #Humanrelevant statt #grausam!
April 10, 2025 at 10:13 AM
safermedicines.org
"In order to successfully tackle cancer, we must embrace its complexity, prioritize prevention, and transition to innovative research methods that use human-focused models"
#betterscience #humanrelevant
www.scienceadvancement.org/reflections/...
Why We Haven't Cured Cancer Yet - Science Advancement and Outreach Division
“Cancer” is a general term for over 200 different diseases, each with unique causes and behaviors. An estimated 53.5 million people lived with cancer in 2022, which means there were 53.5 million diffe...
www.scienceadvancement.org
November 22, 2024 at 8:05 PM
safermedicines.org
The time has come for a decisive shift away from animal testing and toward technologies that prioritize accuracy, facilitate precision medicine and establish more humane research practices #betterscience #humanrelevant
February 10, 2025 at 6:08 PM
safermedicines.org
The time may come when we look back and realise that animal experiments have been a huge and costly distraction, a path we might have done better to completely avoid.
#betterscience
#humanrelevant safermedicines.org/blog_post/mi...
Misplacement, replacement, displacement - Safer Medicines
When considering the use of animals in research intended to have relevance for human health, the time may come when we look back and realise that animal experiments have been a huge and costly distrac...
safermedicines.org
October 28, 2025 at 8:58 AM
safermedicines.org
Human-focused life sciences are moving from vision to implementation.

#betterscience is #humanrelevant

Huge thanks to all the brilliant participants 👏

safermedicines.org/royal-societ...
Royal Society meeting a great success! - Safer Medicines
Our 2-day Science+ meeting, co-organised with Professor Geoff Pilkington on behalf of the Alliance for Human Relevant Science, was an exceptional experience. We were deeply honoured to have so many ou...
safermedicines.org
February 11, 2026 at 9:59 AM
ertrunnell.bsky.social
🤝 Hesperos, Inc. and Bayer teamed up to create the first-ever human microphysiological system that can model central nervous system stress.

Read the paper by Autar et al. 👇
doi.org/10.1016/j.bi...

#neuroskyence #invitro #mps #organonchips #brainonachip #NAMs #humanrelevant 🧪
A graphic with a photo of a white and grey rat standing up but slightly crouching in front of a geometric blue and yellow background. The text reads: “Business Wire. October 7, 2025. “This advance demonstrates the ability of Human-on-a-Chip systems to replicate complex neurological processes such as stress-related cognitive decline without the need for animal studies.” James Hickman, PhD. Chief Scientist, Hesperos.
October 20, 2025 at 4:06 PM
safermedicines.org
Sign and share this petition to make sure animal testing is REALLY phased out in the UK! #betterscience #humanrelevant you.38degrees.org.uk/petitions/a-...
A real roadmap to phase out animal testing
The government promised to work towards phasing out animal testing. Now they're creating a roadmap to make it happen, but it needs to be an ambitious and detailed plan, with clear milestones to drive ...
you.38degrees.org.uk
September 3, 2025 at 7:37 AM
ertrunnell.bsky.social
It’s time for the research community to move away from animal models and invest fully in #HumanRelevant science—approaches that use human cells, tissues, and data.

Expand this thread for some highlights of human-based #HIVResearch 👇

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September 18, 2025 at 1:11 PM
caare.bsky.social
Rather than try to create a “mouse model” of Tourette Syndrome, as has been done for years, scientists at Yale University conducted an animal-free study by examining human brain tissue. #animals #humanrelevant #Tourette
www.elsevier.com/about/press-...
April 21, 2025 at 12:17 PM
safermedicines.org
“I’m not a mouse, I’m not even a monkey,” she says. “When we are doing drug testing in animals, and then we take it into a clinical trial in humans we see a lot of drugs fail.” #betterscience #humanrelevant

www.theguardian.com/environment/...
The world is shifting away from using animals in research. Will Australia get left behind?
Australia’s lack of transparency and funding leave it on the outer as researchers worldwide explore alternatives for training, study and testing
www.theguardian.com
February 17, 2025 at 10:18 AM
safermedicines.org
The Alliance for Human Relevant Science welcomes the government's roadmap to phase out animal testing. We are ready to help deliver and accelerate this vital transition. #betterscience #humanrelevant

www.humanrelevantscience.org/replacing-an...
Replacing animals in science - Human Relevant Science
The UK Government has (11.11.2025) published its strategy for “Replacing animals in science”, to deliver on a key pledge from the Labour Party’s election manifesto to set out a clear plan to reduce an...
www.humanrelevantscience.org
November 30, 2025 at 3:08 PM
ertrunnell.bsky.social
🖥️ #InSilico tech is revolutionizing #RareDisease research! 🦓

Computational models, machine learning, and digital twins can:
✅ Integrate complex data
✅ Simulate biology
✅ Predict actionable outcomes

#HumanRelevant 🧪 🧬
Figure 1 from the linked paper showing a ‘Schematic representation of in silico methods across the rare disease therapeutic pipeline.’ The caption reads: “Methods span from diagnosis (e.g., variant analysis) to drug discovery (e.g., virtual screening), preclinical development (e.g., disease modeling), and clinical trials (e.g., virtual patients, pharmacokinetics/ pharmacodynamics (PK/PD) modeling). Abbreviations: PBPK physiologically based pharmacokinetics, popPK population pharmacokinetics, HTS, high-throughput screening, QSAR quantitative structure–activity relationship.”
January 9, 2026 at 8:51 PM
rhanowski.bsky.social
Gehirnorganoide –winzige, im Labor gezüchtete Modelle des menschlichen Gehirns –sind moderne Forschungssysteme, die zahlreiche Fragen, die man über Jahrzehnte erfolglos in Tierversuchen erforscht hat, humanrelevant und tierleidfrei beantworten können.
www.aerzte-gegen-tierversuche.de/de/news/mini...
Mini-Gehirne revolutionieren die Forschung
Einblicke in Gehirnerkrankungen und Einfluss von Stress in der Schwangerschaft Gehirnorganoide – winzige, im Labor gezüchtete Modelle des menschl...
www.aerzte-gegen-tierversuche.de
June 19, 2025 at 2:00 PM
safermedicines.org
Registration for live-stream closes Monday 2nd Feb. On-demand recording will be available soon.

#betterscience is #humanrelevant

royalsociety.org/science-even...
A human focus for 21st century life sciences | Royal Society
Science+ meeting organised by Professor Geoffrey J Pilkington, Ms Rebecca Ram, and Ms Kathy Archibald
royalsociety.org
February 1, 2026 at 8:35 AM
safermedicines.org
Patients would benefit from human-relevant science in place of preclinical animal tests that risk incorrect predictions of safety and efficacy. #betterscience #humanrelevant safermedicines.org/blog_post/on...
On Clinical Trials Day - May 20 2025 - Safer Medicines
May 20th every year marks Clinical Trials Day, to recognise the day in 1747 when James Lind, a ship’s surgeon in the British Royal Navy initiated what is considered to be one of the first ever clinica...
safermedicines.org
May 20, 2025 at 7:51 AM
safermedicines.org
UK government needs to quickly up its game, or be left in the dirt by the forward-thinking US FDA, NIH and EPA, who now realise that #betterscience is #humanrelevant

safermedicines.org/blog_post/as...
Astonishing April! - Safer Medicines
It all began on 10th April, when the US Food and DrugAdministration (FDA) announced its intention to take ‘a groundbreaking step to advance public health’ by using ‘more effective, human-relevant meth...
safermedicines.org
May 2, 2025 at 9:10 AM
safermedicines.org
Animal tests are notoriously bad at identifying liver-toxic drugs. Now is the time to implement predictive complex in vitro models of human livers into routine drug testing #betterscience #humanrelevant

www.frontiersin.org/journals/dru...
Frontiers | Perspective: How complex in vitro models are addressing the challenges of predicting drug-induced liver injury
www.frontiersin.org
February 19, 2025 at 2:29 PM
safermedicines.org
“We’re not going to be able to replace animals in biomedical research with the meager investments that federal agencies are now making.”

#betterscience #humanrelevant

thehighwire.com/news/house-o...
House Oversight Committee Exposes “Barbaric” Taxpayer-Funded Animal Experiments - The HighWire
Lawmakers detail shocking taxpayer-funded animal experiments, including drugged puppies, transgender lab rats, and gain-of-function research.
thehighwire.com
February 14, 2025 at 11:43 AM
mimetas.bsky.social
The FDA is phasing out animal testing for therapies like monoclonal antibodies, pushing for human-relevant “NAMs” like organ-on-a-chip, AI toxicity models & human cell assays. A huge shift we’ve long championed at MIMETAS.

🔗 Read the announcement: www.fda.gov/news-events/... #HumanRelevant
FDA Announces Plan to Phase Out Animal Testing Requirement for Monoclonal Antibodies and Other Drugs
FDA Plans to Phase Out Animal Testing Requirement
www.fda.gov
April 15, 2025 at 12:37 PM