#IDPfun2
We’ve successfully held the 2nd yearly meeting of the IDP2Biomed and IDPFun2 projects at the University of Padova!
Grateful for the inspiring discussions and the growing momentum of our community—looking forward to what comes next!
#IDP2Biomed #IDPFun2 #IntrinsicallyDisorederedProtein #EUFunding
November 17, 2025 at 11:54 AM
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Excited to share our latest preprint! We reveal how intrinsically disordered protein regions (IDRs) harbor critical pathogenic mutations, often overlooked in clinical genomics. 🧬
www.biorxiv.org/content/10.1...

#Genomics #Bioinformatics #AlphaMissense #IDPs #SLiMs #Dlab #IDP2Biomed #IDPfun2
Pathogenic Missense Mutations in Intrinsically Disordered Regions Reveal Functional and Clinical Signals
Intrinsically disordered regions (IDRs) play essential roles in signaling and regulation but remain under-characterized in the context of human disease. We analyzed nearly one million ClinVar missense...
www.biorxiv.org
May 7, 2025 at 9:56 AM
The first IDPFun2 International Conference was held in Buenos Aires between April 14–16, under the theme “Unravelling the complexity of Intrinsically Disordered Proteins: Technological Innovations an Future Prospectives.” Zsuzsanna Dosztányi gave a fascinating presentation at the event.
April 17, 2025 at 11:45 AM