Ibrahim Maalouf - Essentielles
YouTube video by Ibrahim Maalouf Official
youtube.com
May 5, 2025 at 4:20 PM
I'm going to take ISCs while I am working the sketches I owe, but just a couple of slots per streaming session until the sketch commission list is complete.
If you're interested, I will take one for today.
If you're interested, I will take one for today.
May 12, 2026 at 5:11 PM
I'm going to take ISCs while I am working the sketches I owe, but just a couple of slots per streaming session until the sketch commission list is complete.
If you're interested, I will take one for today.
If you're interested, I will take one for today.
From our partners at the USAID Alumni Association (UAA):
We are delighted to spread the news that the UAA (usaidalumni.org) has expanded membership to all Institutional Support Contractors (ISCs) who worked for USAID for 18 months or more.
Please visit their website for more information.
We are delighted to spread the news that the UAA (usaidalumni.org) has expanded membership to all Institutional Support Contractors (ISCs) who worked for USAID for 18 months or more.
Please visit their website for more information.
April 10, 2026 at 10:33 PM
From our partners at the USAID Alumni Association (UAA):
We are delighted to spread the news that the UAA (usaidalumni.org) has expanded membership to all Institutional Support Contractors (ISCs) who worked for USAID for 18 months or more.
Please visit their website for more information.
We are delighted to spread the news that the UAA (usaidalumni.org) has expanded membership to all Institutional Support Contractors (ISCs) who worked for USAID for 18 months or more.
Please visit their website for more information.
#WeekendRead! #InflammasomePower! Lebon Hofree Biton &co show @natimmunol.nature.com that salmonella sensing by intestinal epithelial cells #ISCs triggers inflammasome activation resulting not only in IL1 production but also in the differentiation of ISCs into protective antimicrobial Paneth cells!
An inflammasome-driven differentiation program in intestinal stem cells protects against Salmonella infection - Nature Immunology
Salmonella-invaded intestinal stem cells activate an inflammasome-driven differentiation program toward antimicrobial Paneth cells, revealing a protective stem cell defense mechanism that helps restri...
doi.org
May 16, 2026 at 2:53 PM
#WeekendRead! #InflammasomePower! Lebon Hofree Biton &co show @natimmunol.nature.com that salmonella sensing by intestinal epithelial cells #ISCs triggers inflammasome activation resulting not only in IL1 production but also in the differentiation of ISCs into protective antimicrobial Paneth cells!
Similarly, USAID's congressionally appropriated funding remains at basically pre-DOGE levels. It would be trivially easy to simply restaff it (maybe fix their fucked up reliance on PSCs and ISCs and actually hire as civil service) and get things up and running within a year or two
April 14, 2026 at 3:40 PM
Similarly, USAID's congressionally appropriated funding remains at basically pre-DOGE levels. It would be trivially easy to simply restaff it (maybe fix their fucked up reliance on PSCs and ISCs and actually hire as civil service) and get things up and running within a year or two
🍔 How do diets shape our intestinal health? Obesogenic diets (high in fat and sugar) expand intestinal stem cells (ISCs), potentially increasing tumorigenesis risk.
🔄 But specific dietary interventions might counteract these effects.
👓 Let's review the current literature! 📚
🧵
1/4
🔄 But specific dietary interventions might counteract these effects.
👓 Let's review the current literature! 📚
🧵
1/4
January 28, 2025 at 6:15 AM
🍔 How do diets shape our intestinal health? Obesogenic diets (high in fat and sugar) expand intestinal stem cells (ISCs), potentially increasing tumorigenesis risk.
🔄 But specific dietary interventions might counteract these effects.
👓 Let's review the current literature! 📚
🧵
1/4
🔄 But specific dietary interventions might counteract these effects.
👓 Let's review the current literature! 📚
🧵
1/4
Jared on SCL:
Star Citizen patches will be monthly and have "storyline" updates using existing features
New features will release a lot slower and have work done in the background - as such, ISCs and SCLs will be moving into a single show on Thursdays.
1/2
#StarCitizen
Star Citizen patches will be monthly and have "storyline" updates using existing features
New features will release a lot slower and have work done in the background - as such, ISCs and SCLs will be moving into a single show on Thursdays.
1/2
#StarCitizen
February 6, 2025 at 5:16 PM
Jared on SCL:
Star Citizen patches will be monthly and have "storyline" updates using existing features
New features will release a lot slower and have work done in the background - as such, ISCs and SCLs will be moving into a single show on Thursdays.
1/2
#StarCitizen
Star Citizen patches will be monthly and have "storyline" updates using existing features
New features will release a lot slower and have work done in the background - as such, ISCs and SCLs will be moving into a single show on Thursdays.
1/2
#StarCitizen
Inside Star Citizen
I encourage all to take the 8:10 to watch this ISC. What we can expect from weekly ISCs this year, new Wikelo armor that looks incredible, teasing of the RSI Hermes, faction based salvaging and mining missions, and much more.
Great start to 2956! #StarCitizen #Squadron42
I encourage all to take the 8:10 to watch this ISC. What we can expect from weekly ISCs this year, new Wikelo armor that looks incredible, teasing of the RSI Hermes, faction based salvaging and mining missions, and much more.
Great start to 2956! #StarCitizen #Squadron42
January 22, 2026 at 6:55 PM
Inside Star Citizen
I encourage all to take the 8:10 to watch this ISC. What we can expect from weekly ISCs this year, new Wikelo armor that looks incredible, teasing of the RSI Hermes, faction based salvaging and mining missions, and much more.
Great start to 2956! #StarCitizen #Squadron42
I encourage all to take the 8:10 to watch this ISC. What we can expect from weekly ISCs this year, new Wikelo armor that looks incredible, teasing of the RSI Hermes, faction based salvaging and mining missions, and much more.
Great start to 2956! #StarCitizen #Squadron42
I am excited to share our work, recently published in PLOS Biology, in which we uncover a mechanism by which intestinal stem cells (ISCs) recognise pathogenic bacteria following infection and promote intestinal regeneration. journals.plos.org/plosbiology/...
September 5, 2026 at 4:11 PM
I am excited to share our work, recently published in PLOS Biology, in which we uncover a mechanism by which intestinal stem cells (ISCs) recognise pathogenic bacteria following infection and promote intestinal regeneration. journals.plos.org/plosbiology/...
USAID has about 10,000 direct hire employed and as many or more PSCs and ISCs (contractors), and other types of contractors. So roughly 20-30k people.
February 5, 2025 at 2:40 AM
USAID has about 10,000 direct hire employed and as many or more PSCs and ISCs (contractors), and other types of contractors. So roughly 20-30k people.
Runaway Train (Soul Asylum) Cover By Gareth Rhodes
YouTube video by 77rhodes
www.youtube.com
February 21, 2025 at 1:27 PM
#LocationLocationLocation! Baghdadi, Kim &co show @science.org that intestinal stem cells #ISCs located at the bottom of the crypts sense a more rigid environment & activate PIEZO to tune their proliferation/differentiation maintaining gut physiology! doi.org/10.1126/scie...
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance
Stem cells perceive and respond to biochemical and physical signals to maintain homeostasis. Yet, it remains unclear how stem cells sense mechanical signals from their niche in vivo. In this work, we ...
doi.org
November 29, 2024 at 5:21 PM
#LocationLocationLocation! Baghdadi, Kim &co show @science.org that intestinal stem cells #ISCs located at the bottom of the crypts sense a more rigid environment & activate PIEZO to tune their proliferation/differentiation maintaining gut physiology! doi.org/10.1126/scie...
New preprint from the lab 🙌 @biorxiv. We found new foxi1 functions in multipotent mucociliary progenitors in #xenopus. 🐸
www.biorxiv.org/content/10.1...
Congrats to 3 first authors Sarah Bowden, Magdalena Brislinger-Engelhardt, Mona Hansen & team!
Fu dwd by
CIBSS
SFB1453_NephGen
dfg
www.biorxiv.org/content/10.1...
Congrats to 3 first authors Sarah Bowden, Magdalena Brislinger-Engelhardt, Mona Hansen & team!
Fu dwd by
CIBSS
SFB1453_NephGen
dfg
Foxi1 regulates multiple steps of mucociliary development and ionocyte specification through transcriptional and epigenetic mechanisms
Foxi1 is a master regulator of ionocytes (ISCs / INCs) across species and organs. Two subtypes of ISCs exist, and both α- and β-ISCs regulate pH- and ion-homeostasis in epithelia. Gain and loss of FOX...
www.biorxiv.org
November 11, 2024 at 6:07 PM
New preprint from the lab 🙌 @biorxiv. We found new foxi1 functions in multipotent mucociliary progenitors in #xenopus. 🐸
www.biorxiv.org/content/10.1...
Congrats to 3 first authors Sarah Bowden, Magdalena Brislinger-Engelhardt, Mona Hansen & team!
Fu dwd by
CIBSS
SFB1453_NephGen
dfg
www.biorxiv.org/content/10.1...
Congrats to 3 first authors Sarah Bowden, Magdalena Brislinger-Engelhardt, Mona Hansen & team!
Fu dwd by
CIBSS
SFB1453_NephGen
dfg
@spac.bsky.social very well represented at #ISCS
1-@ana-vranic.bsky.social discussed why cascades are a tricky measure to study information spread
2-Mariana Silva won the #BestPresentation award for showing political bias in the online space (media, search engines, LLMs)! (work led by Íris Damião)
1-@ana-vranic.bsky.social discussed why cascades are a tricky measure to study information spread
2-Mariana Silva won the #BestPresentation award for showing political bias in the online space (media, search engines, LLMs)! (work led by Íris Damião)
June 8, 2026 at 9:59 AM
@spac.bsky.social very well represented at #ISCS
1-@ana-vranic.bsky.social discussed why cascades are a tricky measure to study information spread
2-Mariana Silva won the #BestPresentation award for showing political bias in the online space (media, search engines, LLMs)! (work led by Íris Damião)
1-@ana-vranic.bsky.social discussed why cascades are a tricky measure to study information spread
2-Mariana Silva won the #BestPresentation award for showing political bias in the online space (media, search engines, LLMs)! (work led by Íris Damião)
Finding joy in celebrating student success this week. Check out Izilda Pereira-Jorge’s FIRST first author paper (of many more to come). In four studies, we examined parents’ perceptions of LGBTQ+ and Black identity-safety cues (ISCs) in 3rd and 8th grade classrooms. Marginalized parents viewed…
March 12, 2025 at 1:29 PM
Finding joy in celebrating student success this week. Check out Izilda Pereira-Jorge’s FIRST first author paper (of many more to come). In four studies, we examined parents’ perceptions of LGBTQ+ and Black identity-safety cues (ISCs) in 3rd and 8th grade classrooms. Marginalized parents viewed…
A great piece of work by the Ferrandon lab to describe the huge importance of Nora virus in #Drosophila stocks. Gut disruption creates susceptibility to coinfection by microbes. Major effects on lifespan, infection, etc...
www.biorxiv.org/content/10.1...
Much needed fly #virus PSA to boot.
1/2
www.biorxiv.org/content/10.1...
Much needed fly #virus PSA to boot.
1/2
February 15, 2025 at 8:53 AM
A great piece of work by the Ferrandon lab to describe the huge importance of Nora virus in #Drosophila stocks. Gut disruption creates susceptibility to coinfection by microbes. Major effects on lifespan, infection, etc...
www.biorxiv.org/content/10.1...
Much needed fly #virus PSA to boot.
1/2
www.biorxiv.org/content/10.1...
Much needed fly #virus PSA to boot.
1/2
Chen, Y., Sun, L. V. (2025). alphaSnap plays a pivotal role in the maintenance of Drosophila ISCs survival and tissue homeostasis. Sci Rep, 15(1):18989 www.nature.com/articles/s41...
αSnap plays a pivotal role in the maintenance of Drosophila ISCs survival and tissue homeostasis - Scientific Reports
Scientific Reports - αSnap plays a pivotal role in the maintenance of Drosophila ISCs survival and tissue homeostasis
www.nature.com
December 19, 2025 at 5:42 PM
Chen, Y., Sun, L. V. (2025). alphaSnap plays a pivotal role in the maintenance of Drosophila ISCs survival and tissue homeostasis. Sci Rep, 15(1):18989 www.nature.com/articles/s41...
"...young people – especially working-class, racialized, and those labelled ‘sexually precocious’ – experienced unprecedented intervention from police in the name of protection, prevention, and discipline."
Read more here: ccie.educ.ubc.ca/watch-morali...
www.youtube.com/watch?v=IScs...
Read more here: ccie.educ.ubc.ca/watch-morali...
www.youtube.com/watch?v=IScs...
Tamara Meyers - Morality Squads, Curfews, and the Sports Solution
YouTube video by CCIE UBC
www.youtube.com
March 26, 2026 at 7:14 PM
"...young people – especially working-class, racialized, and those labelled ‘sexually precocious’ – experienced unprecedented intervention from police in the name of protection, prevention, and discipline."
Read more here: ccie.educ.ubc.ca/watch-morali...
www.youtube.com/watch?v=IScs...
Read more here: ccie.educ.ubc.ca/watch-morali...
www.youtube.com/watch?v=IScs...
NEW content online!
NOTUM-mediated stem cell competition in CRC
Nature Reviews Cancer, Published online: 12 May 2025; doi:10.1038/s41568-025-00827-6In this Journal Club. Gupta and Das discuss a study demonstrating how Apc-deficient intestinal stem cells (ISCs) gain a competitive advantage over normal ISCs through the upregulation of NOTUM.
www.nature.com
May 12, 2025 at 3:41 PM
NEW content online!
Now we could focus again on the question: How can Notch signaling generate more than two mucociliary cell types in specific proportions to each other? In the Xenopus epidermis, we have 4: Ionocytes (ISCs), ciliated (MCCs), secretory (SSCs) and basal (BCs) cells.
March 16, 2026 at 9:14 PM
Now we could focus again on the question: How can Notch signaling generate more than two mucociliary cell types in specific proportions to each other? In the Xenopus epidermis, we have 4: Ionocytes (ISCs), ciliated (MCCs), secretory (SSCs) and basal (BCs) cells.
Excited to be heading to ISCS next week in Luxembourg, a few spaces still available for this very cool imaging science conference iscs2025.com
Also pleased to be able to travel Flight free, following discussions with @markmiodownik.bsky.social and insights from @seatsixtyone.bsky.social
Also pleased to be able to travel Flight free, following discussions with @markmiodownik.bsky.social and insights from @seatsixtyone.bsky.social
Symposium
The International Symposium on Computational Sensing (ISCS) brings together researchers from optical microscopy, electron microscopy, RADAR, astronomical imaging, biomedical imaging, remote sensing, a...
iscs2025.com
May 27, 2025 at 3:54 PM
Excited to be heading to ISCS next week in Luxembourg, a few spaces still available for this very cool imaging science conference iscs2025.com
Also pleased to be able to travel Flight free, following discussions with @markmiodownik.bsky.social and insights from @seatsixtyone.bsky.social
Also pleased to be able to travel Flight free, following discussions with @markmiodownik.bsky.social and insights from @seatsixtyone.bsky.social