#ImagingMassCytometry
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haoyin.bsky.social
ROCK inhibitors #Fasudil #Belumosudil suppresses 🐭 #SubretinalFibrosis with laser-induced choroidal neovascularization

Cool #ImagingMassCytometry 25 antibodies with metal isotopes for single-cell ocular pathology🤠

#ResearchSquare 2025
www.researchsquare.com/article/rs-4...
August 6, 2025 at 11:24 AM
jrmansfield.bsky.social
An excellent paper by Joel Eliason, Jared K. Burks, Suhendan Ekmekcioglu et al on characterizing the spatial immune architecture in melanoma using imaging mass cytometry #IMC.

www.frontiersin.org/journals/imm...

@standardbiology.bsky.social @visiopharm.bsky.social #SpatialBio #ImagingMassCytometry
www.frontiersin.org
May 3, 2025 at 2:48 PM
jrmansfield.bsky.social
An exciting new paper from Pamela Ohashi, Hartland Jackson, et al, on CD103+CD56+ innate lymphoid cells in the tumor microenvironment.

aacrjournals.org/cancerimmuno...

#spatialbiology #TME #IMC #imagingmasscytometry @standardbiology.bsky.social #UHN_Research
CD103+CD56+ ILCs are associated with an altered CD8+ T-cell profile within the tumour microenvironment
Abstract. Immunotherapies have had unprecedented success in the treatment of multiple cancer types, albeit with variable response rates. Unravelling the complex network of immune cells within the tumo...
aacrjournals.org
February 16, 2025 at 12:51 PM
jrmansfield.bsky.social
An excellent paper by Daniel W Rosenberg et al using #IMC makes the cover of the issue of AACR Journals Cancer Prevention Research being handed out at #AACR25. Congratulations!

aacrjournals.org/cancerpreven...

#ImagingMassCytometry @standardbiology.bsky.social #SpatialBio
April 29, 2025 at 11:33 AM
haoyin.bsky.social
SpiDe-Sr
Spatial proteomic images denoising & super-resolution
#SpatialProteomics

⏫peak signal-to-noise ratio & cell extraction accuracy in #ImagingMassCytometry

Also applicable to immunofluorescent images

vs SRCNN KernelGAN RCAN

#NatureComms 2024
www.nature.com/articles/s41...
March 29, 2024 at 7:26 PM
jrmansfield.bsky.social
New from @usc.edu : Peter Kuhn & James Hicks use CyTOF + IMC to profile rare immune-like CTCs (CD45⁺/CK⁺) in metastatic breast cancer. A novel hybrid cell type with clinical potential.

www.nature.com/articles/s43...

#SpatialBio @standardbiology.bsky.social #ImagingMassCytometry
Simultaneous expression of epithelial and immune cell markers in circulating tumor cells identified in patients with stage 4 breast cancer - Communications Medicine
Higa et al. analyzed circulating cells expressing cancer and immune cell markers in breast cancer patients. Based on genomic and protein expression profiling, they show that the cells were unlike prev...
www.nature.com
July 27, 2025 at 3:54 PM