#SpatialOmics #ImagingMassSpec #SpatialTranscriptomics

MISTy
Multiview Intercellular SpaTial modeling framework

View/spatial scale-specific features
Intraview - same location
Juxtaview - local neighborhood
Paraview - distnat

#GenomeBiol 2022
genomebiology.biomedcentral.com/articles/10....

Spatial Multi-Omics of mouse hindlimb #SkeletalMuscle (TA EDL SOL)

Serial sections
Transcriptomics TOMOseq
Metabolomics #ImagingMassSpec

Intriguing complementary distribution b/w NAD+ & Glutamate/Succinate/Glutamine/2-Oxoglutarate

#CommsBio 2024
www.nature.com/articles/s42...

⏫Fatty Acid Uptake & β-oxidation in Asthmatic Bronchial #SmoothMuscleCell

#Proteomics #ImagingMassSpec 👤bronchial biopsy➡️
⏫CPT2
⏬Arachidonate Stearate Linoleate
in bronchial SMC Not Epithelium

CPT1i, CPT2i, LDLR Ab ⏬bronchial SMC prolifer & OXPHOS

#ERJ 2021
publications.ersnet.org/content/erj/...