LightNews — News, ranked by scholars

Manuel Mendoza

@longchrom.bsky.social

What a wonderful surprise this morning to see our work highlighted. Thanks @juanmartin-serrano.bsky.social and @jcb.org !

Journal of Cell Biology @jcb.org · Nov 12

Spotlight: @juanmartin-serrano.bsky.social highlights work from Dam, Moreno, Brownlow, @longchrom.bsky.social et al. (rupress.org/jcb/article/...), which reveals how Srs2/PARI act as a missegregated chromatin sensor for NoCut, delaying cytokinetic abscission. rupress.org/jcb/article/...
#Cytokinesis

November 13, 2025 at 11:32 AM

Journal of Cell Biology

@jcb.org

Spotlight: @juanmartin-serrano.bsky.social highlights work from Dam, Moreno, Brownlow, @longchrom.bsky.social et al. (rupress.org/jcb/article/...), which reveals how Srs2/PARI act as a missegregated chromatin sensor for NoCut, delaying cytokinetic abscission. rupress.org/jcb/article/...
#Cytokinesis

November 12, 2025 at 5:01 PM

Journal of Cell Biology

@jcb.org

Sensing danger at the bridge. Juan Martin-Serrano (@juanmartin-serrano.bsky.social) @kingscollegelondon.bsky.social discusses new work from Dam, Moreno, Brownlow, @longchrom.bsky.social and colleagues (rupress.org/jcb/article/...), in Spotlight: rupress.org/jcb/article/...
#Cytokinesis

November 19, 2025 at 2:45 PM

Stuart Neil

@tetherin.bsky.social

Epic paper from @juanmartin-serrano.bsky.social group KCL in collaboration with with Wes Sundquist and Adam Frost.

ESCRT-III filaments coat naked DNA that remains in the cytokinetic bridge between daughter cells to prevent DNA damage while the cells engage regulatory processes to sort the problem.

Juan Martin Serrano @juanmartin-serrano.bsky.social · Jul 15

Very proud to see this paper out. This is an incredible collaboration with the labs of Wes Sundquist and Adam Frost. @uofubiochem.bsky.social @kingslsm.bsky.social

www.nature.com/articles/s41...

ESCRT-III assembles around mis-segregated DNA to protect genome stability - Nature Structural & Molecular Biology

The authors show that persistent ultrafine DNA bridges become coated by membranes and the ESCRT-III proteins CHMP1B and IST1, which protect the genome within from damage.

www.nature.com

July 17, 2026 at 8:50 AM

Manuel Mendoza

@longchrom.bsky.social

In which we share News (and our Views) on breakthrough work from the labs of @juanmartin-serrano.bsky.social, Wes Sundquist and Adam Frost. A protective ESCRT sleeve for ultrafine DNA bridges! Fun writing with @barrallabeth.bsky.social. @natsmb.nature.com doi.org/10.1038/s415...

During cytokinesis, unresolved UFBs can become enclosed within a nuclear-envelope-derived membrane sleeve that contains LEM2 and other inner nuclear membrane proteins. The authors11 propose that CHMP1B- and IST1-containing ESCRT-III polymers assemble within this membrane compartment, surrounding the DNA bridge and forming a coaxial structure, with the DNA occupying the core, the ESCRT assembly forming an intermediate sleeve, and the nuclear-envelope-derived membrane constituting the outer layer. This DNA-associated ESCRT pool is distinct from the canonical CEP55-dependent ESCRT-III machinery at the midbody, which normally mediates plasma membrane scission during abscission. Aurora B-dependent NoCut signaling may coordinate the activities of these two ESCRT assemblies, delaying abscission while protecting UFBs from breakage or inappropriate immune recognition. Whether the Aurora B-dependent NoCut checkpoint, which inhibits the midbody ESCRT-III pool, also regulates the DNA-associated ESCRT-III assembly remains unclear (dashed arrow).

July 29, 2026 at 9:59 AM

King's Faculty of Life Sciences & Medicine

@kingslsm.bsky.social

🧬 Every time a cell divides, it must accurately copy and protect its DNA. Researchers at King's, led by @juanmartin-serrano.bsky.social have discovered a previously unknown mechanism that helps protect DNA during cell division.

Read more: www.kcl.ac.uk/news/new-mec...

New mechanism discovered which protects DNA during cell division | King's College London

Researchers at King’s College London have discovered a previously unknown mechanism that helps protect cells’ genetic information during cell division.

www.kcl.ac.uk

July 29, 2026 at 9:40 AM

Don Porqué

@donporque.bsky.social

¿Quién es Ana Martín, la hija de Lydia Bosch? #6deMarzo #FelizViernes #LydiaBosch #AnaMartin #JuanMartin #AndreaMolina #GalaSolidaria #SonarDespierto #Photocall #TikTokEspana #Corazon #Famosos #Actualidad #Celebrities donporque.com/quien-es-ana...

¿Quién es Ana Martín, la hija de Lydia Bosch?

Ana Martín debuta en público junto a Juan, habla de Lydia Bosch y perfila su sitio en una de las familias más seguidas del momento en España. Ana Martín ya no es solo la hija discreta de Lydia Bosch q...

donporque.com

March 6, 2026 at 3:18 PM

Rockefeller University Press

@rupress.org

Spotlight @jcb.org: @juanmartin-serrano.bsky.social highlights work from Dam, Moreno, Brownlow, @longchrom.bsky.social et al. (rupress.org/jcb/article/...), which reveals how Srs2/PARI act as a missegregated chromatin sensor for NoCut, delaying cytokinetic abscission. rupress.org/jcb/article/...