A kidney organoid-based readout to assess disease activity in primary and recurrent focal segmental glomerulosclerosis

doi.org/10.1016/j.kint.2025.01.018

#OpenAccess #FSGS #kidneyorganoid

Pro-longed (+1 wk) FGF9 treatment in Takasato #KidneyOrganoid
👉Delays ectopic #Chondrogenesis
👉⏫AQP2
👉Reduces mesenchymal compartment
👉Enhances vascularization

The performance when implanted?🧐

Vanessa LaPointe lab #NPJRegMed 2025
www.nature.com/articles/s41...