#LC/MS
Can LC-MS help solve bioanalysis challenges where ligand-binding assays fall short?

Read the article highlight and explore what standardized LC-MS can bring to bioanalysis: evosep.com/bioanalysis/#article-highlight
November 4, 2026 at 1:00 PM
A practical and robust method for quantification of long-chain PFAS in food matrices using 18O-water-based generation of internal standards and LC–ESI–MS/MS

Takayama, Higuchi, Ozawa et al.

Talanta

https://www.sciencedirect.com/science/article/pii/S0039914026014256

#stableisotopes
A practical and robust method for quantification of long-chain PFAS in food matrices using 18O-water-based generation of internal standards and LC–ESI–MS/MS
ABSTRACT Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are persistent organic contaminants of global concern. In response to increasingly stringent international regulations, including the addition of long-chain perfluoroalkyl carboxylic acids (LC-PFCA) to the Stockholm Convention in 2025, ac
www.sciencedirect.com
October 31, 2026 at 7:23 PM
LC-MS/MS confirmation: less than 1% of oral berberine reaches systemic circulation as parent compound.

https://news.gmj.ge/briefs/data-point-less-than-1-of-oral-berberine-reaches-the-bloodstream/
Data Point: Less Than 1% of Oral Berberine Reaches the Bloodstream
LC-MS/MS confirmation: less than 1% of oral berberine reaches systemic circulation as parent compound.
news.gmj.ge
October 31, 2026 at 1:27 PM
Our partner UJEP represented #STREP at 27th School of Mass Spectrometry in Frymburk, CZ (Sept 21-25) 🔬

Researcher Andrea Vernerová presented a poster on optimizing analytical methodologies for PFAS determination in textile recycling matrices using LC-MS/MS 📊
November 2, 2026 at 9:48 AM
PXD073525 🚨

LC-MS/MS analysis of hippocampal small extracellular vesicles in a rat model of febrile seizures

🚨 New dataset alert! 🚨
November 3, 2026 at 3:00 PM
Pairing SLIM's separation power with Waters' Xevo™ MRT MS speed and resolution enables superior bottom-up analysis of complex proteomes versus LC-MS alone, making high-resolution ion mobility accessible to more scientists.​
November 3, 2026 at 2:39 PM
PXD073251 🚨

LC-MS analysis of human melanoma cell line response to eIF4F inhibition and MEK inhibition.

🚨 New dataset alert! 🚨
November 2, 2026 at 3:00 PM
Ex-PI: Danaher $DHR scales LC-MS; AI tightens focsu, buy +35% analysi. https://finance.yahoo.com/technology/ai/articles/dhr-q3-deep-dive-execution-081427013.html
November 2, 2026 at 8:06 PM
Keep learning with ASMS!

Four online short courses this December cover LC-MS/MS, troubleshooting, untargeted metabolomics, and high-resolution MS.

Advance registration ends Nov. 13. Fees increase $50 afterward!

https://www.asms.org/conferences/online-short-courses

#ASMS2026
Online Short Courses
www.asms.org
November 1, 2026 at 3:10 PM
A High-Sensitivity and High-Throughput LC-MS Workflow for Low-Input and Single-Cell Proteomics https://www.biorxiv.org/content/10.64898/2026.10.26.762077v1
October 29, 2026 at 2:46 PM
A High-Sensitivity and High-Throughput LC-MS Workflow for Low-Input and Single-Cell Proteomics https://www.biorxiv.org/content/10.64898/2026.10.26.762077v1
October 29, 2026 at 2:46 PM
PXD061271 🚨

Molecular analysis of Cgl-ILC interaction supernatants; Description: Viable Candida glabrata cells were co-cultured with pulmonary ILCs. The precipitated proteins were then analyzed using LC-MS

🚨 New dataset alert! 🚨
November 2, 2026 at 7:00 PM
Ms LC says could we have a Daphne minor photo! ❤️❤️
October 27, 2026 at 4:13 PM
Ex-PI: Danaher $DHR scales LC-MS proteomcs; assay AI increases focsu; buy +35%. https://finance.yahoo.com/technology/ai/articles/dhr-q3-deep-dive-execution-081427013.html
October 31, 2026 at 6:04 PM
COMING 17 NOVEMBER: NanoShield™ 1x100 C18! Perfectly paired with Aurora Series™ 5, our newest trap offers faster loading, simpler installation and forward- or reversed-flush flexibility for high-throughput LC-MS. Early benchmarks beat PepMap. Pre-order now to be first in line: bit.ly/4A9m1AO
November 4, 2026 at 6:59 AM
IsoPairFinder: A Computational Workflow for Prioritizing LC–MS Feature Pairs Representing Candidate Microbial Pathway Intermediates from Stable Isotope Tracing Metabolomics

Journal of the American Society for Mass Spectrometry

https://pubs.acs.org/doi/10.1021/jasms.6c00253

#stableisotopes
IsoPairFinder: A Computational Workflow for Prioritizing LC–MS Feature Pairs Representing Candidate Microbial Pathway Intermediates from Stable Isotope Tracing Metabolomics
Abstract. Functional annotation of microbial genes lags behind the pace of genome sequencing, leaving major gaps in our understanding of microbial metaboli
pubs.acs.org
November 1, 2026 at 7:46 PM
Validated LC-MS/MS quantification of kynurenine pathway metabolites and pathway-balance ratios in brain tissue and microglial culture supernatant: application to neonatal stroke https://www.biorxiv.org/content/10.64898/2026.10.29.762714v1
October 30, 2026 at 4:45 PM
Validated LC-MS/MS quantification of kynurenine pathway metabolites and pathway-balance ratios in brain tissue and microglial culture supernatant: application to neonatal stroke https://www.biorxiv.org/content/10.64898/2026.10.29.762714v1
October 30, 2026 at 4:45 PM
Validated LC-MS/MS quantification of kynurenine pathway metabolites and pathway-balance ratios in brain tissue and microglial culture supernatant: application to neonatal stroke #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2026.10.29.762714v1
October 30, 2026 at 5:03 PM
Chemical profiling and antioxidant potential of the ethanolic extract of the Odontotermes formosanus fungus comb: an integrated LC–MS/MS and computational study #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-11156052/latest
October 30, 2026 at 2:04 PM
A new peak at 0.12 % in a stability sample, above the 0.10 % identification threshold of ICH Q3A(R2). Release is on hold.

From your LC-MS data we deliver ranked candidate structures, an M7 class for each and the measurement that confirms it.

Which peak took you longest to name?
November 3, 2026 at 7:22 AM
PXD069187 🚨

Benchmarking plasma proteomics depletion and enrichment workflows prior to LC-MS/MS analysis

🚨 New dataset alert! 🚨
October 29, 2026 at 11:00 AM
Deamidation in one line: asparagine (and glutamine, more slowly) becomes aspartate. On LC-MS it reads as a mass shift of about +1 Da. Heat, moisture and high pH make it faster.

Research use only.
Catalog: shop.cavirpeptides.com #peptides #chemistry #science
November 2, 2026 at 9:20 PM
What if valuable biological information is hiding in signals we can’t identify? HRIM adds a structural dimension to LC-MS, helping resolve isomers and coeluting species across the “dark multi-ome.”

Read more: www.chromatographyonline.com/view/illumin...
October 28, 2026 at 4:06 PM