‼️Our latest study, “Loss of STAT3 in acute myeloid leukemia favors tissue infiltration linked to CXCR4 signaling,” is now out in @bloodneoplasia.bsky.social
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...
October 15, 2025 at 2:53 PM
‼️Our latest study, “Loss of STAT3 in acute myeloid leukemia favors tissue infiltration linked to CXCR4 signaling,” is now out in @bloodneoplasia.bsky.social
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...
This is also important for people studying MLL-AF9 leukemia. Congrats to all authors.
An early Christmas present for those interested in chromatin and transcription! Fantastic work from @au-ho-yu.bsky.social and @aleksszczurek.bsky.social . Thanks to Inge and Michiel for their help. Please repost!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
SET1/MLL complexes control transcription independently of H3K4me3
Histone H3 lysine 4 trimethylation (H3K4me3) at gene promoters is thought to play a central role in gene transcription. H3K4 methylation is deposited by the SET1 (A/B) and MLL (1-4) multi-protein comp...
www.biorxiv.org
December 11, 2025 at 1:06 PM
This is also important for people studying MLL-AF9 leukemia. Congrats to all authors.
The authors included RRIDs in their None paper! RRIDs improve reproducibility in scientific research. #RRID #methodsmatter #STMpublishing
Molecular insights into chemotherapy resistance mediated by MLL-AF9 fusion gene in pediatric B-cell acute lymphoblastic leukemia
doi.org
July 23, 2025 at 7:03 AM
The authors included RRIDs in their None paper! RRIDs improve reproducibility in scientific research. #RRID #methodsmatter #STMpublishing
RRID:IMSR_JAX:009079 was used by the authors of the Toxicology paper "Benzene-induced hematotoxicity enhances the self-renewal ability of HSPCs in Mll-Af9 mice". RRIDs like this improve reproducibility in scientific research. #STMpublishing #STMpublishing
doi.org
February 1, 2025 at 8:01 AM
RRID:IMSR_JAX:009079 was used by the authors of the Toxicology paper "Benzene-induced hematotoxicity enhances the self-renewal ability of HSPCs in Mll-Af9 mice". RRIDs like this improve reproducibility in scientific research. #STMpublishing #STMpublishing
The authors included RRIDs in their None paper! We value the author's support of reproducibility. #ReproducibleResearch #accelerateopenscience #accelerateopenscience
CD123 Targeted Epigenetic Nanotherapy for Fusion Oncoprotein MLL-AF9 Rearranged Acute Myeloid Leukemia in Preclinical and Patient Derived Xenograft Models
doi.org
September 17, 2025 at 7:00 AM
The authors included RRIDs in their None paper! We value the author's support of reproducibility. #ReproducibleResearch #accelerateopenscience #accelerateopenscience
PXD077604 🚨
Description: Proteomic and Phosphoproteomic profiling of Linc-Kit+ cells from normal C57BL/6J mice and GFP+Linc–Kit + cells from MLL-AF9-driven AML mouse model
🚨 New dataset alert! 🚨
Description: Proteomic and Phosphoproteomic profiling of Linc-Kit+ cells from normal C57BL/6J mice and GFP+Linc–Kit + cells from MLL-AF9-driven AML mouse model
🚨 New dataset alert! 🚨
July 25, 2026 at 11:00 AM
PXD077604 🚨
Description: Proteomic and Phosphoproteomic profiling of Linc-Kit+ cells from normal C57BL/6J mice and GFP+Linc–Kit + cells from MLL-AF9-driven AML mouse model
🚨 New dataset alert! 🚨
Description: Proteomic and Phosphoproteomic profiling of Linc-Kit+ cells from normal C57BL/6J mice and GFP+Linc–Kit + cells from MLL-AF9-driven AML mouse model
🚨 New dataset alert! 🚨
New study in @natcomms.nature.com
Thrombopoietin increases susceptibility for EVI1 + KMT2A-MLLT3-driven AML expressing stem cell genes linked to poor outcome
#AML, #KMT2A-MLLT3, #MLL-AF9, #EVI1, #TPO
www.nature.com/articles/s41...
Thrombopoietin increases susceptibility for EVI1 + KMT2A-MLLT3-driven AML expressing stem cell genes linked to poor outcome
#AML, #KMT2A-MLLT3, #MLL-AF9, #EVI1, #TPO
www.nature.com/articles/s41...
Thrombopoietin increases susceptibility for EVI1 + KMT2A-MLLT3-driven AML expressing stem cell genes linked to poor outcome - Nature Communications
Fusion genes involving KMT2A rearrangements are frequent oncogenic drivers of acute myeloid leukaemia (KMT2A-r AML) but the cell of origin remains unclear. Here, using preclinical models of EVI1 posit...
www.nature.com
January 5, 2026 at 4:31 AM
New study in @natcomms.nature.com
Thrombopoietin increases susceptibility for EVI1 + KMT2A-MLLT3-driven AML expressing stem cell genes linked to poor outcome
#AML, #KMT2A-MLLT3, #MLL-AF9, #EVI1, #TPO
www.nature.com/articles/s41...
Thrombopoietin increases susceptibility for EVI1 + KMT2A-MLLT3-driven AML expressing stem cell genes linked to poor outcome
#AML, #KMT2A-MLLT3, #MLL-AF9, #EVI1, #TPO
www.nature.com/articles/s41...