A recent preprint introduces MaveMD, a clinical interface for MaveDB that integrates MAVE data with ClinVar and ClinGen to support variant classification and reduce VUS uncertainty.

Uncover the science behind it:  www.medrxiv.org/content/10.1...

Next up at MSS 2026 comes Benjamin Capodanno of the Brotman Baty Institute, whose talk on MaveMD discusses this functional data resource for genomic medicine.

#VariantEffect26
#MaveMD
#AtlasOfVariantEffectsAlliance

MaveMD: A functional data resource for genomic medicine #RareDisease #Genetics www.medrxiv.org/content/10.1...

Kicking off this afternoon's session is Bryony Thompson from the Royal Melbourne Hospital, whose presentation is about the lessons learned from applying functional data in real-world clinical variant classification.

#VariantEffect26
#MAVE #MaveMD
#AtlasOfVariantEffectsAlliance

MaveMD: A functional data resource for genomic medicine https://www.medrxiv.org/content/10.1101/2025.11.15.25336228v1