November 18, 2024 at 9:31 PM
🥳Just published @nature.com. Over 25 years after the discovery of SPO11 as the enzyme responsible for initiating meiotic recombination, we finally succeeded in reconstituting its DNA cleavage activity.🧵
www.nature.com/articles/s41...
www.nature.com/articles/s41...
SPO11 dimers are sufficient to catalyse DNA double-strand breaks in vitro - Nature
A biochemical system recapitulates the hallmarks of meiotic double-strand break formation, with mouse SPO11 catalysing break formation in the absence of any partners and remaining covalently atta...
www.nature.com
February 19, 2025 at 5:04 PM
Yay #FluorescentFriday! A live #celegans hermaphrodite germline undergoing oogenesis with a fluorescent synaptonemal complex, a meiotic chromosome structure, marking the chromosomes in each nucleus. Movie taken by @cahooncori.bsky.social #meiosis4eva
November 15, 2024 at 8:41 PM
Yay #FluorescentFriday! A live #celegans hermaphrodite germline undergoing oogenesis with a fluorescent synaptonemal complex, a meiotic chromosome structure, marking the chromosomes in each nucleus. Movie taken by @cahooncori.bsky.social #meiosis4eva
Congratulations @cohenlab.bsky.social! #Meiosis4Eva
Reversible male contraceptive that halts sperm production [via Cornell U] 🧪🥼🕺💃🚫🧒
"Unintended pregnancies account for nearly 44% of all pregnancies worldwide...a biologically defined and reversible control point within the spermatogenic program"
www.pnas.org/doi/10.1073/...
#male #contraceptive
"Unintended pregnancies account for nearly 44% of all pregnancies worldwide...a biologically defined and reversible control point within the spermatogenic program"
www.pnas.org/doi/10.1073/...
#male #contraceptive
Meiotic prophase I disruption as a strategy for nonhormonal male contraception using small-molecule inhibitor JQ1 | PNAS
Developing safe, reversible, and nonhormonal male contraceptives has been hindered
by the lack of defined biological windows that can be transientl...
www.pnas.org
April 8, 2026 at 3:17 AM
Congratulations @cohenlab.bsky.social! #Meiosis4Eva
Heading to sunny San Diego for #CellBio2024 this week? ☀️🌅 Join us for the "#Meiosis4Eva: Frontiers in Meiosis and Germ Cell Biology" Subgroup! 🗓️ Wed Dec 18th 9:00 - 10:30am, Room 33B. 👉 bit.ly/49okQkZ #Meiosis4Eva #meiosis4ever
December 9, 2024 at 7:57 PM
Heading to sunny San Diego for #CellBio2024 this week? ☀️🌅 Join us for the "#Meiosis4Eva: Frontiers in Meiosis and Germ Cell Biology" Subgroup! 🗓️ Wed Dec 18th 9:00 - 10:30am, Room 33B. 👉 bit.ly/49okQkZ #Meiosis4Eva #meiosis4ever
For #MicroscopyMonday, here is a pachytene stage chromosome from a #zebrafish spermatocyte, imaged with superresolution microscopy by postdoc @cahooncori.bsky.social who's starting her own lab at CSU Fort Collins in January 2025. #meiosis4eva
November 18, 2024 at 6:47 PM
For #MicroscopyMonday, here is a pachytene stage chromosome from a #zebrafish spermatocyte, imaged with superresolution microscopy by postdoc @cahooncori.bsky.social who's starting her own lab at CSU Fort Collins in January 2025. #meiosis4eva
My first #FluorescenceFriday post . Arabidopsis thaliana anthere. Nuclear membrane protein. Crescent-shaped distribution in meiocytes #meiosis4eva
November 22, 2024 at 11:43 AM
My first #FluorescenceFriday post . Arabidopsis thaliana anthere. Nuclear membrane protein. Crescent-shaped distribution in meiocytes #meiosis4eva
#Meiosis4eva starter pack. I am sure I missed many so please self nominate by commenting or just DMing me go.bsky.app/P3BJYze
November 9, 2024 at 7:28 PM
#Meiosis4eva starter pack. I am sure I missed many so please self nominate by commenting or just DMing me go.bsky.app/P3BJYze
Natural variation modifies centromere proximal meiotic crossover frequency and segregation distortion in Arabidopsis thaliana biorxiv.org/content/10.1... new work from us on centromere inheritance and organisation @matt-naish.bsky.social @plantevolution.bsky.social @genomeevolution.bsky.social
January 6, 2025 at 12:25 PM
Thanks to @urszulamcclurg.bsky.social for creating a Meiosis4Eva starter pack! I'm guessing there are a few people who might want to use it/join it.
go.bsky.app/P3BJYze
go.bsky.app/P3BJYze
November 11, 2024 at 8:31 PM
Thanks to @urszulamcclurg.bsky.social for creating a Meiosis4Eva starter pack! I'm guessing there are a few people who might want to use it/join it.
go.bsky.app/P3BJYze
go.bsky.app/P3BJYze
Looking forward to seeing you all in Switzerland!🇨🇭apply now!
#meiosis4eva
#meiosis4eva
Registration now open for the 2025 EMBO workshop on Meiosis! June 22-26, 2025, Engelberg, Switzerland.
Deadline for abstract submissions and registration is Feb 15th, 2025. Lots of speaker slots will be selected from abstracts, so apply now! meetings.embo.org/event/25-mei...
Deadline for abstract submissions and registration is Feb 15th, 2025. Lots of speaker slots will be selected from abstracts, so apply now! meetings.embo.org/event/25-mei...
Meiosis: Exploring diversity to discover the fundamentals
Meiosis is an essential cell division for sexual reproduction and fertility across eukaryotes. It involves a series of tightly regulated processes, including entry into meiosis, pairing of homologs, …
meetings.embo.org
December 11, 2024 at 11:51 PM
Looking forward to seeing you all in Switzerland!🇨🇭apply now!
#meiosis4eva
#meiosis4eva
Out now in @nature.com Research Briefings: Rhynchospora tenuis makes gametes without meiotic crossovers yet retains sexual reproduction. Only seeds that restore the parental chromosome combination are viable, giving clone-like offspring
#meiosis4eva #SexualReproduction
www.nature.com/articles/d41...
#meiosis4eva #SexualReproduction
www.nature.com/articles/d41...
A plant that reproduces sexually but has clone-like offspring
Only seeds that replicate the parental combination of chromosomes remain viable.
www.nature.com
September 24, 2026 at 1:05 PM
Out now in @nature.com Research Briefings: Rhynchospora tenuis makes gametes without meiotic crossovers yet retains sexual reproduction. Only seeds that restore the parental chromosome combination are viable, giving clone-like offspring
#meiosis4eva #SexualReproduction
www.nature.com/articles/d41...
#meiosis4eva #SexualReproduction
www.nature.com/articles/d41...
Congratulations @francescacole.bsky.social, to you and all the authors! 🎉🥳#Meiosis4Eva
Using recombination and cytological assays, Frasca et al. determined the role of MutSgamma in mouse spermatocytes stabilizing D-loops and promoting successful interhomolog pairing during recombination.
Read more in #GENETICS: buff.ly/OweGIOn
Read more in #GENETICS: buff.ly/OweGIOn
July 8, 2025 at 6:08 PM
Congratulations @francescacole.bsky.social, to you and all the authors! 🎉🥳#Meiosis4Eva
Beautiful work and modeling from the @lacefieldlab.bsky.social! #Meiosis4Eva
New in MBoC
A study in budding yeast shows that timely release of mRNAs from the RNA-binding protein Rim4 is essential for meiotic exit, preventing cells from re-entering the cell cycle after meiosis II.
https://www.molbiolcell.org/doi/10.1091/mbc.E25-08-0379
A study in budding yeast shows that timely release of mRNAs from the RNA-binding protein Rim4 is essential for meiotic exit, preventing cells from re-entering the cell cycle after meiosis II.
https://www.molbiolcell.org/doi/10.1091/mbc.E25-08-0379
July 27, 2026 at 3:50 PM
Beautiful work and modeling from the @lacefieldlab.bsky.social! #Meiosis4Eva
2024 Mid-Atlantic Meiosis Mini-Symposium!! 🐭🪱🪰🧬🦠Co-organized with @scienceleah.bsky.social and @florpratto.bsky.social at NIH. Amazing talks from trainees and new PIs🎉 #meiosis4eva
November 16, 2024 at 4:16 PM
2024 Mid-Atlantic Meiosis Mini-Symposium!! 🐭🪱🪰🧬🦠Co-organized with @scienceleah.bsky.social and @florpratto.bsky.social at NIH. Amazing talks from trainees and new PIs🎉 #meiosis4eva
For #FluorescenceFriday, here's some meiotic spindles trying to segregate chromosomes with multiple crossovers in #celegans. Image taken by Jeremy Hollis from our collaboration with Sadie Wignall's lab. #meiosis4eva
November 22, 2024 at 5:08 PM
For #FluorescenceFriday, here's some meiotic spindles trying to segregate chromosomes with multiple crossovers in #celegans. Image taken by Jeremy Hollis from our collaboration with Sadie Wignall's lab. #meiosis4eva
Six more years—plus a lot of blood, sweat, and tears—later, we are thrilled to finally share it: a cytological framework of female meiosis in Arabidopsis!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A cytological framework of female meiosis in Arabidopsis
Female and male meiosis often differ in many aspects, such as their duration and the frequency as well as the positioning of crossovers. However, studying female meiosis is often very challenging and ...
www.biorxiv.org
August 25, 2025 at 7:00 PM
Super happy to see this review published - the first author, Cong Wang was co-advised as a graduate student by Yingxiang and I, and is a really fabulous independent scientist now.
doi.org/10.1080/1949...
doi.org/10.1080/1949...
March 18, 2024 at 4:01 PM
Just to let people know: I’m here too, representing #Meiosis4Eva 🤗🧪
In light of recent influxes, would be good to get a thread of starter packs for cell/molecular/mechanistic biologists.
I did one quite a while ago: still great people, but now even more obviously missing important people than when I did it.
Come on gang, help me out!
go.bsky.app/2z8z1nW
I did one quite a while ago: still great people, but now even more obviously missing important people than when I did it.
Come on gang, help me out!
go.bsky.app/2z8z1nW
October 19, 2024 at 3:02 PM
Just to let people know: I’m here too, representing #Meiosis4Eva 🤗🧪
This is not a drill, British Meiosis Meeting 2025 will be in Liverpool 🎉. Join us on 26-27 of March docs.google.com/forms/d/e/1F...
Abstract deadline 20th Feb. Most talks reserved for ECRs (PhDs, Post-Docs & NewPIs)! With an amazing keynote Joao Matos. @meiosis4eva
Abstract deadline 20th Feb. Most talks reserved for ECRs (PhDs, Post-Docs & NewPIs)! With an amazing keynote Joao Matos. @meiosis4eva
January 16, 2025 at 7:21 AM
This is not a drill, British Meiosis Meeting 2025 will be in Liverpool 🎉. Join us on 26-27 of March docs.google.com/forms/d/e/1F...
Abstract deadline 20th Feb. Most talks reserved for ECRs (PhDs, Post-Docs & NewPIs)! With an amazing keynote Joao Matos. @meiosis4eva
Abstract deadline 20th Feb. Most talks reserved for ECRs (PhDs, Post-Docs & NewPIs)! With an amazing keynote Joao Matos. @meiosis4eva
We have updated our preprint, in response to reviews organized by @elife.bsky.social: www.biorxiv.org/content/10.1...
🧪 #Meiosis4Eva
🧪 #Meiosis4Eva
January 2, 2025 at 6:41 PM
We have updated our preprint, in response to reviews organized by @elife.bsky.social: www.biorxiv.org/content/10.1...
🧪 #Meiosis4Eva
🧪 #Meiosis4Eva
I’m happy to announce that our preprint is out! 🧬🐭
We show that the mouse HSR selfish DNA kills embryos that do not inherit it through a toxin–antidote system, thereby increasing its transmission to the next generation. ⚡
Feedback is welcome!
@takashiakeralab.bsky.social
#SelfishDNA #meiosis4eva
We show that the mouse HSR selfish DNA kills embryos that do not inherit it through a toxin–antidote system, thereby increasing its transmission to the next generation. ⚡
Feedback is welcome!
@takashiakeralab.bsky.social
#SelfishDNA #meiosis4eva
www.biorxiv.org
March 7, 2026 at 4:10 PM
I’m happy to announce that our preprint is out! 🧬🐭
We show that the mouse HSR selfish DNA kills embryos that do not inherit it through a toxin–antidote system, thereby increasing its transmission to the next generation. ⚡
Feedback is welcome!
@takashiakeralab.bsky.social
#SelfishDNA #meiosis4eva
We show that the mouse HSR selfish DNA kills embryos that do not inherit it through a toxin–antidote system, thereby increasing its transmission to the next generation. ⚡
Feedback is welcome!
@takashiakeralab.bsky.social
#SelfishDNA #meiosis4eva
Interested in meiosis or reproductive cell biology?
Consider submitting your work to #Meiosis4Eva: The Cell Biology of Reproduction, a Minisymposium at ASCB | EMBO Cell Bio 2026!
📅 Abstract deadline for talk consideration: June 9, 2026.
#CellBio2026 #ASCB
Consider submitting your work to #Meiosis4Eva: The Cell Biology of Reproduction, a Minisymposium at ASCB | EMBO Cell Bio 2026!
📅 Abstract deadline for talk consideration: June 9, 2026.
#CellBio2026 #ASCB
June 9, 2026 at 4:31 AM
Interested in meiosis or reproductive cell biology?
Consider submitting your work to #Meiosis4Eva: The Cell Biology of Reproduction, a Minisymposium at ASCB | EMBO Cell Bio 2026!
📅 Abstract deadline for talk consideration: June 9, 2026.
#CellBio2026 #ASCB
Consider submitting your work to #Meiosis4Eva: The Cell Biology of Reproduction, a Minisymposium at ASCB | EMBO Cell Bio 2026!
📅 Abstract deadline for talk consideration: June 9, 2026.
#CellBio2026 #ASCB
Latest work from amazing postdoc @cahooncori.bsky.social is out in eLife! It was submitted before the new review system. Cori identifies sexual dimorphisms in meiotic chromosome structures that differentially regulate recombination. #meiosis4eva elifesciences.org/articles/84538
October 5, 2023 at 7:13 PM
Latest work from amazing postdoc @cahooncori.bsky.social is out in eLife! It was submitted before the new review system. Cori identifies sexual dimorphisms in meiotic chromosome structures that differentially regulate recombination. #meiosis4eva elifesciences.org/articles/84538
Official website for EMBO meiosis 2025 is live now! Looking forward to seeing you in Switzerland next June! #meiosis4eva
meetings.embo.org/event/25-mei...
meetings.embo.org/event/25-mei...
Meiosis: Exploring diversity to discover the fundamentals
Meiosis is an essential cell division for sexual reproduction and fertility across eukaryotes. It involves a series of tightly regulated processes, including entry into meiosis, pairing of homologs, …
meetings.embo.org
November 14, 2024 at 3:45 AM
Official website for EMBO meiosis 2025 is live now! Looking forward to seeing you in Switzerland next June! #meiosis4eva
meetings.embo.org/event/25-mei...
meetings.embo.org/event/25-mei...