Necessity is the mother of invention. Most synthetic chemistry innovations are driven by our desire to make molecules. In the first half of the 20th century, much of this work was inspired by natural ...

Necessity is the mother of invention. Most synthetic chemistry innovations are driven by our desire to make molecules. In the first half of the 20th century, much of this work was inspired by natural ...

2-Iodoxybenzoic acid (IBX) is a versatile oxidant used in chemical synthesis. It has been employed as a reagent in more than 1400 publications since its initial use as an oxidant described in 1994. Wh...

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We report the development of a multifunctional reagent for the direct conversion of carboxylic acids to aldehydes under mild conditions and with exquisite chemoselectivity. These reactions proceed in aqueous solvent at room temperature in 20 min, can be done open to air, require no metal catalysts, and employ near-stoichiometric amounts of both reducing agent and a mild base. No over-reduction, epimerization, or reduction of other reducible functional groups is observed. With this reagent, a broad scope of complex, drug-like aryl and alkyl carboxylic acids can be reduced directly to aldehydes.

Job Description Within the Development Sciences and Clinical Supply (DSCS) organization, the Digital Program Manager will advance the purpose and aspiration of our Company’s DSCS Digital Strategy to e...

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