#Microbiota-driven
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erictopol.bsky.social
Did you know there are 3 mechanisms for hunger, and one is gut microbiota driven?
the gut microbiome schematic mechanism for hunger
January 26, 2025 at 3:38 PM
evolvedbiofilm.bsky.social
Spatially restricted immune and microbiota-driven adaptation of the gut

- in #Nature

www.nature.com/articles/s41...
Spatially restricted immune and microbiota-driven adaptation of the gut - Nature
Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...
www.nature.com
November 22, 2024 at 8:01 AM
saltybitchables.bsky.social
Despite cuts in cancer research funding, advances continue.

We are so close to eradicating cancer.

A single bacterial dose from frog gut microbiota eliminated tumors in mice.

We need funds to continue research. This is personal.

#ProudBlue #ProScience

scitechdaily.com/naturally-oc...
Naturally Occurring Bacteria Completely Eradicate Tumors in Mice With a Single Dose
A bacterium from frog gut microbiota eliminated tumors in mice by selectively colonizing tumors and triggering both direct cell killing and immune-driven anticancer responses.
scitechdaily.com
April 11, 2026 at 1:23 PM
asm.org
Understanding microbiota resilience in the face of imbalances is crucial for maintaining host health. This #mBio review explores microbiota resilience, emphasizing the interplay between microbial communities and host-driven environmental controls. asm.social/2qW
During homeostasis, host-driven habitat filters, such as the maintenance of anoxia by epithelia β-oxidation and stable iron levels through dietary intake, curate a diverse microbiota dominated by beneficial obligate anaerobic primary fermenters. Upon onset of diverse inflammatory intestinal disease states, including inflammatory bowel disease and colorectal cancer, host habitat filters become compromised. Inflammation-driven increases in luminal oxygen levels favor facultatively anaerobic pathobionts at the expense of commensal obligate anaerobes. In parallel, host nutritional immunity factors, such as lactoferrin, sequester iron to defend against potential bacterial pathogens. These environmental perturbations can drive the microbiota to an imbalanced, pro-inflammatory dysbiosis. However, a resilient microbiota can withstand or rapidly recover from these perturbations until host habitat filters are restored. The mechanisms that mediate this resilience and restoration of host habitat
May 28, 2025 at 6:33 PM
evolvedbiofilm.bsky.social
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth

@cp-cellhostmicrobe.bsky.social from Gabriel Castrillo

www.cell.com/cell-host-mi...
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth
Custódio et al. reveal a microbiota-driven mechanism that requires the repression of a plant defense genetic circuit. This mechanism modulates the growth-defense trade-off to prioritize leaf growth ov...
www.cell.com
March 1, 2025 at 12:57 PM
dejongepmi.bsky.social
🌱 We're hiring! Join our team as a PhD candidate to explore plant–microbiota host specificity. Plant biology/microbiology background needed; bioinformatics skills a big plus💻! Apply by mid-June. www.uu.nl/en/organisat... #uubeta #plantmicrobiome #microbiota
PhD Position on Decoding Plant Microbiota–Host Specificity Using AI
Join us to generate data and build AI-driven models to decode plant–microbiota host specificity!
www.uu.nl
May 15, 2025 at 9:36 AM
dejongepmi.bsky.social
One more week to apply for an open PhD position in my team at Utrecht University. Interested in genetics, genomics, bioinformatics, microorganisms and plant-microbiota interactions, don't hesitate and apply! www.uu.nl/en/organisat...
PhD Position on Decoding Plant Microbiota–Host Specificity Using AI
Join us to generate data and build AI-driven models to decode plant–microbiota host specificity!
www.uu.nl
June 6, 2025 at 6:33 PM
daltmann.bsky.social
www.nature.com/articles/s41...
My friend @chrischirp.bsky.social pointed out I can't just lazily paste links to a paper of interest without any explanation! We all buy into gut microbiota shaping immune populations and programmes, but this study adds huge granularity, by anatomical region and subset
November 27, 2024 at 8:13 AM
drmichaelway.bsky.social
Now for something completely different - Way lab does immunology - check out our @science.org paper - Branched actin networks mediate macrophage-dependent host-microbiota homeostasis. The work was driven by the 2 first authors @luiz90vasc.bsky.social @shainahuang.bsky.social
November 14, 2025 at 9:16 AM
lozanzi.bsky.social
#WeekendRead! #LocationLocationLocation! Amazing @Nature by @touficmayassi.bsky.social, Xavier &co showing regional specialization of the gut at the spatial (single cell) level! Strong resilience after inflammation & ILC2 are key in middle colon adaption to microbiota! www.nature.com/articles/s41...
Spatially restricted immune and microbiota-driven adaptation of the gut - Nature
Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...
www.nature.com
November 23, 2024 at 2:56 PM
cancercoreeurope.bsky.social
#CCESumSchool25 Day 4 💻
• Lectures: Microbiota, AI-driven & Computational Oncology
• 2nd round of participant talks
• Workshop: Using cBioPortal

@vhio.bsky.social @ki.se @nct-heidelberg.bsky.social @gustaveroussy.fr @nkinl.bsky.social @crukcamcentre.bsky.social
October 10, 2025 at 6:47 AM
evolvedbiofilm.bsky.social
Evaluation of combined root exudate and rhizosphere microbiota sampling approaches to elucidate plant–soil–microbe interactions

@newphyt.bsky.social by @carmen-escudero.bsky.social et al
with @bulgarelli-d.bsky.social

nph.onlinelibrary.wiley.com/doi/10.1111/...
Evaluation of combined root exudate and rhizosphere microbiota sampling approaches to elucidate plant–soil–microbe interactions
Deciphering the root exudate-driven interplay between plants and the rhizosphere microbiota is essential for understanding plant adaptation to the environment and future-proofing crop production. ...
nph.onlinelibrary.wiley.com
May 21, 2026 at 2:43 PM
gobletcellguy.bsky.social
Interesting new paper from the Xavier lab - identifying (among other things) a possible link between microbiota-dependent regulation of regionally restricted #gobletcell subsets via ILC2s:
www.nature.com/articles/s41...
Spatially restricted immune and microbiota-driven adaptation of the gut - Nature
Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...
www.nature.com
December 2, 2024 at 10:18 PM
tatsuyanobori.bsky.social
Spatially restricted immune and microbiota-driven adaptation of the gut www.nature.com/articles/s41...
Spatially restricted immune and microbiota-driven adaptation of the gut - Nature
Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...
www.nature.com
November 20, 2024 at 5:03 PM
natmicrobiol.nature.com
Dive into our November issue featuring:

🪆nested archaeal symbioses
🌱microbiota driven drought responses in plants
🏗️ BAM complex in Bacteroidota
💨microbial fermentative growth in the gut
🍸hospital-specific phage therapy cocktail

and much more..!

www.nature.com/nmicrobiol/v...
November 3, 2025 at 4:31 PM
natrevgastrohep.nature.com
New online! Helicobacter pylori, microbiota and gastric cancer — principles of microorganism-driven carcinogenesis
Helicobacter pylori, microbiota and gastric cancer — principles of microorganism-driven carcinogenesis
Nature Reviews Gastroenterology & Hepatology, Published online: 26 February 2025; doi:10.1038/s41575-025-01042-2Helicobacter pylori has a role in gastric carcinogenesis, among other bacteria. This Review elucidates the role of pathogenic microbes in…
www.nature.com
February 26, 2025 at 10:29 AM
labwaggoner.bsky.social
Within hours of initiating high fat diet, microbiota-driven inflammation coordinates with lipid accumulation in ILC3s to trigger mitochondrial lipid peroxidation and ILC3 cell death @cp-immunity.bsky.social @harvardmed.bsky.social
www.cell.com/immunity/ful...
March 31, 2026 at 6:15 PM
borklab.bsky.social
In "Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota", @inanna-nalytica.bsky.social showed that a supposed T2D #microbiome signature is actually driven by drug treatment with metformin (2015) www.nature.com/artic...
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
Nature - There is growing evidence from metagenome-wide association studies that several common human disorders, such as type 2 diabetes mellitus (T2D), are associated with intestinal dysbiosis, an...
www.nature.com
December 1, 2024 at 2:01 PM
natmetabolism.nature.com
NEWS&VIEWS | W Zhong, K Wang & A Zarrinpar
‪@ucsandiego.bsky.social‬

A study demonstrates that modulation of hypothalamic circuits can rapidly alter gut microbiota composition.
🧪
https://bit.ly/40ONngn ?utm_source=bluesky&utm_medium=social&utm_campaign=natmetab
Mind over microbiota: neurons call the shots in the gut - Nature Metabolism
Although the gut microbiota can influence brain function, evidence for brain activity-driven changes in microbial communities is limited. Here, the authors provide direct support for bidirectional communication in the brain-to-gut axis by demonstrating that modulation of hypothalamic circuits can rapidly alter gut microbiota composition.
bit.ly
July 10, 2025 at 7:01 PM
natrevmicro.nature.com
#weekendreading 🔬

Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth 🌿

@cellpress.bsky.social #microsky

www.cell.com/cell-host-mi...
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth
Custódio et al. reveal a microbiota-driven mechanism that requires the repression of a plant defense genetic circuit. This mechanism modulates the growth-defense trade-off to prioritize leaf growth ov...
www.cell.com
February 28, 2025 at 11:39 AM
nature.com
Nature research paper: Microbiota-mediated induction of beige adipocytes in response to dietary cues

go.nature.com/4rdQ8Cq
Microbiota-mediated induction of beige adipocytes in response to dietary cues - Nature
In mice, a low-protein diet leads to a gut-microbiota-driven remodelling of adipose tissue towards brown fat, showing that gut microorganisms have a role in detecting and responding to a lack of protein.
go.nature.com
March 9, 2026 at 6:51 PM
pauleric70.bsky.social
scitechdaily.com?p=512511
Naturally Occurring Bacteria Completely Eradicate Tumors in Mice With a Single Dose
A bacterium from frog gut microbiota eliminated tumors in mice by selectively colonizing tumors and triggering both direct cell killing and immune-driven anticancer responses.
scitechdaily.com
April 10, 2026 at 11:10 PM
insilicoplants.bsky.social
PhD Position on Decoding Plant Microbiota–Host Specificity Using AI
MICROP project at Utrecht
www.uu.nl/en/organisat... #PlantSciJobs
PhD Position on Decoding Plant Microbiota–Host Specificity Using AI
Join us to generate data and build AI-driven models to decode plant–microbiota host specificity!
www.uu.nl
June 13, 2025 at 3:10 PM
labwaggoner.bsky.social
Gut microbiota–derived N,N,N-trimethyl-5-aminovaleric acid is a modulator of acute graft-versus-host disease in CNS @jem.org
rupress.org/jem/article-...
Gut microbiota–derived TMAVA is a modulator of acute CNS-GVHD
In this study, we report that microbiota depletion exacerbates acute graft-versus-host disease in the central nervous system, driven by microglial activati
rupress.org
July 8, 2025 at 4:09 PM
touficmayassi.bsky.social
1/ Keen to share the story of my postdoc research out in @natureportfolio.bsky.social! We built a massive resource characterizing the spatial landscape of the gut—and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇
www.nature.com/articles/s41...
Spatially restricted immune and microbiota-driven adaptation of the gut - Nature
Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...
www.nature.com
November 21, 2024 at 10:21 PM