To Liverpool, to inspect some microelectrodes.
August 16, 2025 at 6:52 AM
To Liverpool, to inspect some microelectrodes.
Chronically implanted microelectrodes change subtle excitatory-inhibitory interactions that alter neurocomputational processes over time, explaining decoder instability and the need to retrain decoding algorithms daily. iopscience.iop.org/article/10.1...
November 25, 2024 at 1:08 AM
Chronically implanted microelectrodes change subtle excitatory-inhibitory interactions that alter neurocomputational processes over time, explaining decoder instability and the need to retrain decoding algorithms daily. iopscience.iop.org/article/10.1...
New Paper from University of Pittsburgh Neural Engineering Group: Dynamic changes in the structure and function of brain mural cells around chronically implanted microelectrodes
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Dynamic changes in structure and function of brain mural cells around chronically implanted microelectrodes
Integration of neural interfaces with minimal tissue disruption in the brain is ideal to develop robust tools that can address essential neuroscience …
www.sciencedirect.com
November 13, 2024 at 1:41 AM
New Paper from University of Pittsburgh Neural Engineering Group: Dynamic changes in the structure and function of brain mural cells around chronically implanted microelectrodes
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Physiologist Ida Henrietta Hyde (d. #OTD 1945) invented one of the earliest intracellular microelectrodes.
+ One of the first women (& first American woman) to earn a PhD in #science from the U. of Heidelberg in Germany, 1896
+ First woman elected, American Physiological Society, 1902
#WomenInSTEM
+ One of the first women (& first American woman) to earn a PhD in #science from the U. of Heidelberg in Germany, 1896
+ First woman elected, American Physiological Society, 1902
#WomenInSTEM
August 22, 2026 at 3:07 PM
Physiologist Ida Henrietta Hyde (d. #OTD 1945) invented one of the earliest intracellular microelectrodes.
+ One of the first women (& first American woman) to earn a PhD in #science from the U. of Heidelberg in Germany, 1896
+ First woman elected, American Physiological Society, 1902
#WomenInSTEM
+ One of the first women (& first American woman) to earn a PhD in #science from the U. of Heidelberg in Germany, 1896
+ First woman elected, American Physiological Society, 1902
#WomenInSTEM
Repeatable, low-drift recordings in behaving non-human primates using flexible microelectrodes
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
January 13, 2026 at 6:25 PM
Repeatable, low-drift recordings in behaving non-human primates using flexible microelectrodes
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
🔬 Diatoms’ secret superpower revealed in scientific first. Scientists at the MBA used tiny single-cell microelectrodes to watch individual diatoms in action.
👉 Read the full story - https://www.mba.ac.uk/diatoms-reveal-hidden-rapid-adaptability-in-carbon-uptake-in-scientific-first/
👉 Read the full story - https://www.mba.ac.uk/diatoms-reveal-hidden-rapid-adaptability-in-carbon-uptake-in-scientific-first/
January 14, 2026 at 10:30 AM
🔬 Diatoms’ secret superpower revealed in scientific first. Scientists at the MBA used tiny single-cell microelectrodes to watch individual diatoms in action.
👉 Read the full story - https://www.mba.ac.uk/diatoms-reveal-hidden-rapid-adaptability-in-carbon-uptake-in-scientific-first/
👉 Read the full story - https://www.mba.ac.uk/diatoms-reveal-hidden-rapid-adaptability-in-carbon-uptake-in-scientific-first/
First cruise with our new M.Sc. students in Biological Oceanography @geomarkiel.bsky.social @uni-kiel.de to sample sediment cores for organic carbon & DNA, image ammunition dumpsites and investigate macrofauna! Thanks to Jens Greinert, Mirjam Perner and teams - and the excellent crew of RV Alkor
November 3, 2025 at 6:06 PM
First cruise with our new M.Sc. students in Biological Oceanography @geomarkiel.bsky.social @uni-kiel.de to sample sediment cores for organic carbon & DNA, image ammunition dumpsites and investigate macrofauna! Thanks to Jens Greinert, Mirjam Perner and teams - and the excellent crew of RV Alkor
#iEEG (yes microelectrodes count!)
Seems the hippocampus can basically think for itself 😲🤣 seriously tho, very cool work! 👇 #neuroskyence
New paper from the Neurosurgery Research Team at BCM! "Learning and language in the unconscious human hippocampus"
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
April 14, 2025 at 5:47 AM
#iEEG (yes microelectrodes count!)
4/ Ida Henrietta Hyde developed one of the first intracellular microelectrodes for stimulating and recording single cells. She opened new ways of studying nervous and circulatory systems, and became the first woman to receive a PhD in physiology from the University of Heidelberg.
February 11, 2026 at 5:41 PM
4/ Ida Henrietta Hyde developed one of the first intracellular microelectrodes for stimulating and recording single cells. She opened new ways of studying nervous and circulatory systems, and became the first woman to receive a PhD in physiology from the University of Heidelberg.
Roughly half of intracortical microelectrodes lose recording capability within a year of implantation. The B.I.O.N.I.C. Lab at Pitt is hiring a postdoc to attack the mechanism on two parallel grant-funded threads. 🧵 (1/7)
June 26, 2026 at 9:53 PM
Roughly half of intracortical microelectrodes lose recording capability within a year of implantation. The B.I.O.N.I.C. Lab at Pitt is hiring a postdoc to attack the mechanism on two parallel grant-funded threads. 🧵 (1/7)
🔬 We delivered sustained electrical stimulation through implanted microelectrodes while imaging microglia in living mouse brain. During stimulation, microglial processes extended preferentially toward the most active neurons. Not toward the electrode. Toward the working cells.
June 7, 2026 at 10:39 AM
🔬 We delivered sustained electrical stimulation through implanted microelectrodes while imaging microglia in living mouse brain. During stimulation, microglial processes extended preferentially toward the most active neurons. Not toward the electrode. Toward the working cells.
Stabilized carbon coating on microelectrodes for scalable and interoperable neurotransmitter sensing
->Nature | More info from EcoSearch
->Nature | More info from EcoSearch
Stabilized carbon coating on microelectrodes for scalable and interoperable neurotransmitter sensing
Overall, the flexible metal microelectrodes and MEAs were constructed by five layers: a Kapton/Polyimide (PI) bilayer as the substrate, a Cr/Au bilayer as the conductor, and SU-8 as an encapsulation layer. We firstly laminated 1 mil Kapton film (Fralock) onto...
www.nature.com
April 7, 2025 at 10:53 PM
Microemulsions making all the noise! Two of our most enjoyed topics (small electrodes and energy storage electrolytes) coming together to get insight for new redox flow battery designs, in collaboration with DOE’s BEES2 EFRC! iopscience.iop.org/article/10.1...
Correlation Between Microscopic Current Fluctuations Observed at Ultra-Microelectrodes and Macroscopic Bulk Electrolysis Performance in Redox-Active Microemulsions - IOPscienceSearch
Correlation Between Microscopic Current Fluctuations Observed at Ultra-Microelectrodes and Macroscopic Bulk Electrolysis Performance in Redox-Active Microemulsions, Armando Santiago-Carboney, Filip Konstantinov, Michael A. Pence, Brian Barth, Adam Imel, Thomas Zawodzinski, Joaquín Rodríguez-López
iopscience.iop.org
November 25, 2024 at 9:51 PM
Microemulsions making all the noise! Two of our most enjoyed topics (small electrodes and energy storage electrolytes) coming together to get insight for new redox flow battery designs, in collaboration with DOE’s BEES2 EFRC! iopscience.iop.org/article/10.1...
Another New finding: Dual-reactive CX3cr1+/Cspg4+ cell population emerges around chronically implanted microelectrodes, shown using 2p imaging of Cspg4-DsRed:CX3cr1-GFP mice over 28 d. These cells increase in number, change states, and display dynamic motility near implant sites.
November 13, 2024 at 2:01 AM
Another New finding: Dual-reactive CX3cr1+/Cspg4+ cell population emerges around chronically implanted microelectrodes, shown using 2p imaging of Cspg4-DsRed:CX3cr1-GFP mice over 28 d. These cells increase in number, change states, and display dynamic motility near implant sites.
I'll add a little #neuroscience story here:
As a postdoc I showed electrical brain stimulation is always going to be hard to control, because microelectrodes activate axons (and dendrites) and so are very sensitive to electrode position. So...1/2
pubmed.ncbi.nlm.nih.gov/19709632/
As a postdoc I showed electrical brain stimulation is always going to be hard to control, because microelectrodes activate axons (and dendrites) and so are very sensitive to electrode position. So...1/2
pubmed.ncbi.nlm.nih.gov/19709632/
June 11, 2026 at 9:40 PM
I'll add a little #neuroscience story here:
As a postdoc I showed electrical brain stimulation is always going to be hard to control, because microelectrodes activate axons (and dendrites) and so are very sensitive to electrode position. So...1/2
pubmed.ncbi.nlm.nih.gov/19709632/
As a postdoc I showed electrical brain stimulation is always going to be hard to control, because microelectrodes activate axons (and dendrites) and so are very sensitive to electrode position. So...1/2
pubmed.ncbi.nlm.nih.gov/19709632/
🔬 We implanted microelectrodes into 2-month-old APP/PS1 mice, a familial Alzheimer's model. These animals do not normally develop MX04-labeled amyloid plaques until 4-5 months.
Following implantation, we observed plaque accumulation 2-3 months ahead of the typical timeline.
Following implantation, we observed plaque accumulation 2-3 months ahead of the typical timeline.
April 19, 2026 at 12:36 PM
🔬 We implanted microelectrodes into 2-month-old APP/PS1 mice, a familial Alzheimer's model. These animals do not normally develop MX04-labeled amyloid plaques until 4-5 months.
Following implantation, we observed plaque accumulation 2-3 months ahead of the typical timeline.
Following implantation, we observed plaque accumulation 2-3 months ahead of the typical timeline.
Synthetic platelets (SP) can provide hemostatic protection of vascular integrity & reduce inflammation. In this study led by @AndrewShoffsta1 lab in collab w @HaimaThr, SP restored BBB & reduced inflammation at intracortical microelectrode implant site.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Systemically administered platelet-inspired nanoparticles to reduce inflammation surrounding intracortical microelectrodes
Intracortical microelectrodes (IMEs) are essential for neural signal acquisition in neuroscience and brain-machine interface (BMI) systems, aiding pat…
www.sciencedirect.com
January 10, 2025 at 6:36 AM
Synthetic platelets (SP) can provide hemostatic protection of vascular integrity & reduce inflammation. In this study led by @AndrewShoffsta1 lab in collab w @HaimaThr, SP restored BBB & reduced inflammation at intracortical microelectrode implant site.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Musk is barely involved and like starship / super heavy it’s a thing that enough time, money, and experimentation can solve and even if it wasn’t getting to be an unwitting human subject for someone with no ethics who wants to put microelectrodes on your brain will ruin your whole day
November 24, 2025 at 6:52 PM
Musk is barely involved and like starship / super heavy it’s a thing that enough time, money, and experimentation can solve and even if it wasn’t getting to be an unwitting human subject for someone with no ethics who wants to put microelectrodes on your brain will ruin your whole day
🧠📈🧪 New research article: www.bionic-vision.org/research-gro...
A method for fabricating tissue-penetrating 3D microelectrodes directly onto planar microelectronics using high-resolution 3D printing via 2-photon polymerization & scalable microfabrication technologies
doi.org/10.1002/advs...
A method for fabricating tissue-penetrating 3D microelectrodes directly onto planar microelectronics using high-resolution 3D printing via 2-photon polymerization & scalable microfabrication technologies
doi.org/10.1002/advs...
Direct‐Print 3D Electrodes for Large‐Scale, High‐Density, and Customizable Neural Interfaces
This paper presents a method for fabricating 3D microelectrode arrays directly onto silicon microelectronics using two-photon polymerization. These customizable, high-density electrodes enable precis...
doi.org
December 1, 2024 at 3:49 AM
🧠📈🧪 New research article: www.bionic-vision.org/research-gro...
A method for fabricating tissue-penetrating 3D microelectrodes directly onto planar microelectronics using high-resolution 3D printing via 2-photon polymerization & scalable microfabrication technologies
doi.org/10.1002/advs...
A method for fabricating tissue-penetrating 3D microelectrodes directly onto planar microelectronics using high-resolution 3D printing via 2-photon polymerization & scalable microfabrication technologies
doi.org/10.1002/advs...
Big news from Phosphoenix: the Amsterdam spin-off has raised €1.3M to advance its visual neuroprosthesis toward a first-in-human study.
Their Fountain Probe uses 1,000+ microelectrodes to stimulate the visual pathway directly, bypassing the eyes.
#BionicVision #Neurotech
lnkd.in/p/e-zaMrC6
Their Fountain Probe uses 1,000+ microelectrodes to stimulate the visual pathway directly, bypassing the eyes.
#BionicVision #Neurotech
lnkd.in/p/e-zaMrC6
PHOSPHOENIX, an Amsterdam-based MedTech startup founded in 2019 by Prof. Pieter Roelfsema, Prof. @Xing Chen, and Dr. Bert Monna as a Netherlands Institute for Neuroscience spin-off, has completed a… |...
PHOSPHOENIX, an Amsterdam-based MedTech startup founded in 2019 by Prof. Pieter Roelfsema, Prof. @Xing Chen, and Dr. Bert Monna as a Netherlands Institute for Neuroscience spin-off, has completed a €1...
lnkd.in
September 19, 2026 at 10:52 PM
Big news from Phosphoenix: the Amsterdam spin-off has raised €1.3M to advance its visual neuroprosthesis toward a first-in-human study.
Their Fountain Probe uses 1,000+ microelectrodes to stimulate the visual pathway directly, bypassing the eyes.
#BionicVision #Neurotech
lnkd.in/p/e-zaMrC6
Their Fountain Probe uses 1,000+ microelectrodes to stimulate the visual pathway directly, bypassing the eyes.
#BionicVision #Neurotech
lnkd.in/p/e-zaMrC6
Firstly, we had to establish ways to measure oxygen partitioning into condensate. We ended up with 2 experimental + 1 simulation (@cg-martini.bsky.social).
Microelectrodes are straight-forward, but requires pellting of condensates. PLIM is more elaborate, but works for dispersed condensates.
Microelectrodes are straight-forward, but requires pellting of condensates. PLIM is more elaborate, but works for dispersed condensates.
February 20, 2026 at 10:32 PM
Firstly, we had to establish ways to measure oxygen partitioning into condensate. We ended up with 2 experimental + 1 simulation (@cg-martini.bsky.social).
Microelectrodes are straight-forward, but requires pellting of condensates. PLIM is more elaborate, but works for dispersed condensates.
Microelectrodes are straight-forward, but requires pellting of condensates. PLIM is more elaborate, but works for dispersed condensates.
For decades, neuroscience chased the action potential — the one-millisecond spike of an individual neuron — by penetrating the cortex with microelectrodes. Precision Neuro made another bet.
Full conversation with Ben Rapoport of @precisionneuro.bsky.social on the Juan Benet Podcast: bit.ly/49puuoC
Full conversation with Ben Rapoport of @precisionneuro.bsky.social on the Juan Benet Podcast: bit.ly/49puuoC
May 13, 2026 at 3:31 PM
For decades, neuroscience chased the action potential — the one-millisecond spike of an individual neuron — by penetrating the cortex with microelectrodes. Precision Neuro made another bet.
Full conversation with Ben Rapoport of @precisionneuro.bsky.social on the Juan Benet Podcast: bit.ly/49puuoC
Full conversation with Ben Rapoport of @precisionneuro.bsky.social on the Juan Benet Podcast: bit.ly/49puuoC
Repeatable, low-drift recordings in behaving non-human primates using flexible microelectrodes https://www.biorxiv.org/content/10.64898/2026.01.09.698500v1
January 11, 2026 at 5:16 AM
Repeatable, low-drift recordings in behaving non-human primates using flexible microelectrodes https://www.biorxiv.org/content/10.64898/2026.01.09.698500v1
Structurally engineered ultrasoft PEDOT:PSS fiber microelectrodes with enhanced electrochemical performance for neural interfaces | Science Advances www.science.org/doi/10.1126/...
Structurally engineered ultrasoft PEDOT:PSS fiber microelectrodes with enhanced electrochemical performance for neural interfaces
A fully organic PEDOT:PSS fiber probe offers softness and stable electrochemical performance for multichannel neural interfacing.
www.science.org
May 28, 2026 at 7:30 PM
Structurally engineered ultrasoft PEDOT:PSS fiber microelectrodes with enhanced electrochemical performance for neural interfaces | Science Advances www.science.org/doi/10.1126/...