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molbioevol.bsky.social
Sudasinghe et al. present the first phylogenomic analysis of Cypriniformes with complete family-level representation and broad genus-level coverage, encompassing 316 species comprising ∼30% of all described genera.

🔗️ doi.org/10.1093/molb...

🖌️ Nadeela Hirimuthugoda

#societyjournal #evobio #molbio
MBE | Phylogenomics of Cypriniformes, the most diverse order of freshwater fishes: consensus, challenges, and limitations Illustrations: Nadeela Hirimuthugoda
November 3, 2026 at 6:01 PM
princetonmolbio.bsky.social
The 2026 MolBio Retreat was Sat. Oct. 10 on the grounds of Educational Testing Service (ETS). Chaired by asst. professors George Ghanim and Ai Ing Lim, the retreat had 250+ attendees, 1 new faculty member, 28 talks, 35 posters, 14 awardees, and 1 DJ! molbio.princeton.edu/news/2026/20...
2026 MolBio Retreat Wrap-Up and Awardees
The 42st annual MolBio Retreat, this year a one-day event on Saturday, October 10, 2026, took place on the grounds of Educational Testing Service (ETS) in the Conant Cafe and Chauncey Conference Cente...
molbio.princeton.edu
November 2, 2026 at 8:46 PM
molbioevol.bsky.social
Coffing @silastittes.bsky.social @stsmall.bsky.social & Kern analyzed genomes of sympatric sister species Octopus bimaculatus and O. bimaculoides, revealing two species with sharply contrasting evolutionary histories.

🔗️ academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
Diversity and divergence of two sympatric, sibling octopus species
Abstract. Coleoid cephalopods have convergently evolved many traits shared with vertebrates, including camera-type eyes, large brain-to-body size ratios, a
academic.oup.com
November 2, 2026 at 5:01 PM
bielleogy.bsky.social
*adds to my molbio class journal club list* So cool!
maitrejl.bsky.social Jean Léon Maître @maitrejl.bsky.social · 9d
What would happen if you stirred the content of nuclei🧬 like a bowl of ramen🍜?
We did exactly that to mouse embryos and the surprise is the absence of surprise!
www.biorxiv.org/content/10.6...
@institutcurie.bsky.social @cnrsbiologie.bsky.social @cmollier.bsky.social
October 30, 2026 at 6:19 PM
princetonmolbio.bsky.social
New! MolBio Quarterly Publications Highlights by Amanda Riccio. Short, not-too-technical summaries of select pubs across the department. Inaugural edition highlights papers from Jonikas, Devenport, and Hughson labs and Senior Lecturer Schottenfeld-Roames. molbio.princeton.edu/news/2026/mo...
MolBio Quarterly Publications Highlights, Fall 2026
Introducing the MolBio Quarterly Publications Highlights, authored by Amanda Riccio. Short, not-too-technical summaries of a small subset of publications from across the department showing our product...
molbio.princeton.edu
November 2, 2026 at 8:52 PM
plasmidlab.com
Three free sequence tools that run in your browser, without an account: reverse complement, six-frame translation, and a restriction site finder that handles circular plasmids and enzymes like BsaI that cut outside their site.

plasmidlab.com/tools/restriction-sites/

#bioinformatics #molbio
Restriction Site Finder: Which Enzymes Cut My DNA? | PlasmidLab
Paste a DNA sequence to see which restriction enzymes cut it, where and how often. Linear or circular, with filters for enzymes that cut once, twice or not at all.
plasmidlab.com
November 7, 2026 at 5:16 PM
merz.bsky.social
not so molbio but pressure injection injuries 😱
October 30, 2026 at 2:04 AM
molbioevol.bsky.social
MBE's November issue is now live! On the cover, we feature Cheng et al., who explore the evolution of deep-sea squat lobsters from hydrothermal vents.

🔗️ academic.oup.com/mbe/issue/43...

#societyjournal #evobio #molbio
Molecular Biology and Evolution | November 2026 cover
November 3, 2026 at 3:57 PM
molbioevol.bsky.social
Wang et al. analyze genome data of four geographically isolated rumpless breeds of chicken. Findings support a model of parallel evolution in a specific cis-regulatory element of the IRX1/IRX2 intergenic region.

🔗️ academic.oup.com/mbe/article/...

📷️ Kun Wang

#societyjournal #evobio #molbio
MBE | Recurrent tandem duplication of a conserved enhancer underlies parallel genetic origins of rumplessness in chickens A rumpless hen of Chinese Piao Chicken, characterized by the complete absence of tail feathers and caudal vertebrae (pygostyle). Author: Kun Wang
October 28, 2026 at 5:03 PM
molbioevol.bsky.social
Xu, @fbaumdicker.bsky.social et al. used feature attribution to interpret CNNs trained for population genetic inference and found that these networks implicitly learn summary statistics.

🔗️ academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
October 28, 2026 at 4:03 PM
molbioevol.bsky.social
Zhou et al. investigate intron evolution in ciliates, a morphologically and genetically diverse unicellular lineage, using a newly sequenced high-quality genome and comparative genomic data from derived and deep-branching lineages.

🔗️ academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
October 27, 2026 at 2:01 PM
molbioevol.bsky.social
Li et al. used genotype-environment association to identify candidate genes associated with pig adaptation to high altitude, temperature fluctuations, varying humidity levels, and ultraviolet (UV) radiation exposure.

🔗️ academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
MBE | Integrative genotype–environment association and single-cell transcriptomic analyses identify candidate mechanisms of environmental adaptation in pigs
October 27, 2026 at 12:30 PM
molbioevol.bsky.social
Wang et al. assembled and compared chromosome-level genomes for all three Procapra gazelle species; results demonstrate that census size alone does not reliably predict genetic risk.

🔗️ academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
MBE | Comparative population genomics reveals evolutionary potential and conservation priorities in three Procapra species
October 28, 2026 at 10:01 AM
microbesinfo.bsky.social
🧬🦠 Scientists developed a fluorescent tagging tool that tracks #Zika and #Chikungunya viral #RNA inside living cells in real time, revealing how these #viruses replicate and interact with host #proteins.

#Virus #RNA #MolBio #Pathogen #Microsky via @sciencex.bsky.social

phys.org/news/2026-10...
Two-in-one tool tracks viral RNA inside live infected cells in real time
Viruses are sneaky intruders, hijacking the internal machinery of host cells and replicating out of sight. Understanding these dynamics is the first step to developing effective antiviral strategies…
phys.org
October 24, 2026 at 12:01 PM
microbesinfo.bsky.social
🧬🦠 Researchers found that the immune protein #CD46 controls T-cell survival and #gene activity, revealing a pathway that may help explain how #HIV persists despite #antiviral treatment.

#Virus #Immunology #TCells #MolBio #Microsky via @sciencex.bsky.social

medicalxpress.com/news/2026-10...
T cell survival protein controls gene activity, offering clues to HIV persistence
A prominent protein on most human cells may be key to unlocking the code that makes humans susceptible to pathogenic bacteria and viruses, including human immunodeficiency virus (HIV), according to a…
medicalxpress.com
October 24, 2026 at 1:30 AM
molbioevol.bsky.social
In a recent MBE article, Koch et al. dive into the evolutionary origins of doppelgänger toxins in cone snails.

Check the video for more details on their findings. The video was produced by @haorancai.bsky.social in the context of the SMBE Fellows Program.

#societyjournal #evobio #molbio
October 22, 2026 at 6:48 PM
molbioevol.bsky.social
De Vrieze, @janaerts.bsky.social & Masschelein study the interplay between host adaptation, genome evolution, and the metabolic capacity of Clostridia.

🔗 academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
Comparative pangenomics unveils distinct host adaptation trends and conserved biosynthetic potential in microbiome Clostridia
Abstract. To thrive in diverse ecological niches, bacteria adopt various lifestyles that range from living freely in the soil to forming close associations
academic.oup.com
October 22, 2026 at 1:03 PM
molbioevol.bsky.social
Tallon, Maladesky, Jabbour-Zahab, @aline-muyle.bsky.social & @thomaslenormand.bsky.social propose to use the proportion of allele topologies as the primary signal for identifying and delimiting sex chromosome strata

🔗 academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
Using gene topologies to partition sex chromosomes into regions with distinct histories
Abstract. Sex chromosomes often evolve through successive recombination arrests, forming evolutionary strata. Accurately describing these strata, their bou
academic.oup.com
October 21, 2026 at 8:30 AM
molbioevol.bsky.social
@deboraycb.bsky.social, @aidaandres.bsky.social, Tim Connallon & @maxreuter.bsky.social support the intuition that a large fraction of loci under balancing selection will be invisible to standard tests for balancing selection.

🔗 academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
Characterizing the detectable and invisible fractions of genomic loci under balancing selection
Abstract. Balancing selection refers to scenarios where selection maintains genetic polymorphisms affecting fitness and its components. Empirical studies h
academic.oup.com
October 16, 2026 at 12:17 PM
molbioevol.bsky.social
Liu et al. characterized the genomic landscape, functional impact, and evolutionary significance of structural variants in three closely related pine species, demonstrating the importance of SVs as a dimension of genomic diversity.

🔗 academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
Uncovering structural variation in conifer gigagenomes: evolutionary insights and technical challenges
Abstract. Structural variants (SVs) are a major yet understudied source of genomic variation in conifers, whose large, repeat-rich genomes have hindered sy
academic.oup.com
October 14, 2026 at 4:03 PM
molbioevol.bsky.social
Asaeda et al. show that functional divergence between somatic- and testis-type CYC proteins in Buergeria frogs is at least partly due to a phenylalanine-to-tyrosine substitution.

🔗 academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
Ancient nuclear genome duplication events in vertebrates facilitated the functional diversification of ohnologous cytochrome c: insights from Buergeria frogs
Abstract. In vertebrates, a nuclear gene encoding mitochondrial cytochrome c (CYC) was duplicated and diverged into one with ubiquitous expression (somatic
academic.oup.com
October 13, 2026 at 7:01 PM
molbioevol.bsky.social
Li & Liu quantified natural selection acting on metabolite abundance in yeast, finding that approximately 28.58% of metabolites were inferred to be potentially under directional selection.

🔗 academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
Natural selection shapes the evolution of the metabolome in Saccharomyces cerevisiae
Abstract. Metabolite abundances represent the ultimate functional outputs of cellular processes and provide a direct link between genotype and phenotype. W
academic.oup.com
October 14, 2026 at 12:02 PM
molbioevol.bsky.social
Murugesan et al. provide very little support for the role of DNA methylation in driving differences in the transcriptional profiles of the two seasonal wing forms of Bicyclus anynana butterflies and in wing metamorphosis.

🔗 academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
October 13, 2026 at 1:00 PM
molbioevol.bsky.social
Miller et al. explored class I/II fumarases, concluding that metabolic signaling and its specific metabolites may provide the driving force for the fumarases' dual function, dual targeting, and interaction with different cellular entities.

🔗 academic.oup.com/mbe/article/...

#societyjournal #molbio
October 13, 2026 at 10:02 AM
molbioevol.bsky.social
Generally, introns shorter than ∼30 bp are considered absent from animals. Hadjez et al. show that such ultra-short introns evolved independently at least twice in animals, in two parasitic lineages.

🔗 academic.oup.com/mbe/article/...

#societyjournal #evobio #molbio
The shortest animal introns: insights from parasitic cnidarians
Abstract. Spliceosomal introns are nearly ubiquitous across eukaryotes, yet the constraints shaping their length remain poorly understood. Generally, intro
academic.oup.com
October 9, 2026 at 3:42 PM