Nature Biomedical Engineering, Published online: 23 September 2026; doi:10.1038/s41551-026-01791-8Unsaturated phospholipids unexpectedly form multilamellar, multivesicular liposomes that efficiently encapsulate hydrophilic drugs and suppress burst release. These structures enable ultra-slow drug release and produce weeks-long sciatic nerve block with tetrodotoxin in rats.

This is dog-gone adorable.

MSC-EVs enhance functional recovery after a motor cortex injury in rhesus monkeys by reducing microglial inflammation, neuronal damage, and myelination deficits. The signaling pathways underlying thes

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The use of oral fosfomycin for urinary tract infections (UTIs) caused by non-Escherichia coli uropathogens is uncertain, including Klebsiella pneumoniae, the second most common uropathogen. A multicompartment bladder infection in vitro model was ...

Recent studies have shown that place cells in the hippocampus possess firing fields that repeat in physically similar, parallel environments. These results imply that it should be difficult for anima...

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ANCA-associated vasculitis may rarely present as multicompartment cardiac involvement and should be considered in severe inflammatory valvuloaortic disease with conduction abnormalities.

Ultrasound versus the Clinician's Eye: Refining the Diagnosis of Pelvic Prolapse A new prospective diagnostic study offers a direct comparison of clinical examination and transperineal ultrasound for assessing multicompartment pelvic organ prolapse (POP). Using intraoperative assessment under spinal anesthesia as the gold standard, the research found that the two methods are complementary rather than interchangeable. While both showed high sensitivity for diagnosing a cystocele, ultrasound provided superior specificity for uterine prolapse and rectocele, and was particularly strong at confirming an enterocele.

Critical illness can disrupt the composition and function of the microbiome, yet comprehensive longi

Cells can dynamically organize reactions through the formation of biomolecular condensates. These viscoelastic networks exhibit complex material properties and mesoscale architectures, including the a...