Photocatalysts can generate radical species from substrates following light excitation. Here the authors report a two-photon bimodal catalysis approach in which the light-activated photocatalyst generates reactive intermediates at opposite redox scales, expanding the accessible redox window.

Nature Catalysis - The reasons for epistasis, wherein mutations interact non-additively, are often not fully understood. Now it is found that shifting the rate-limiting step from substrate binding...

Catalytic access to axially chiral diaryl ethers remains limited by the difficulty of enantioselective C–O bond formation. Now peptide-mimic phosphonium salts enable atroposelective nucleophilic aromatic substitution-driven C–O bond construction, affording axially enantioenriched diaryl ethers.

The branched pentose sugar d-apiose forms borate ester-polysaccharide crosslinks essential for plant cell wall development. Here the authors elucidate the...

The sugar d-apiose is important in plant cell wall polysaccharides. Here the authors elucidate the complex, multistep biosynthetic pathway for its production using enzyme crystal structures and computational analysis.

Nanoconfinement effects are crucial in any process that i...