Photocatalysts can generate radical species from substrates following light excitation. Here the authors report a two-photon bimodal catalysis approach in which the light-activated photocatalyst gener...

Nature Catalysis, Published online: 02 November 2026; doi:10.1038/s41929-026-01628-2Zirconium catalysis has remained largely confined to Lewis acid and redox chemistry, with only isolated examples of photocatalytic C–H activation. Now trifunctional zirconium catalysis enables modular benzylamine synthesis from alkanes, aldehydes and nitriles by integrating photochemical, redox and Lewis acid reactivity.

Alt: Crushed It: Man Says YES

Here, the authors show that a Bifidobacterium PNGaseA uses a β-sheet cradle to recognize N-glycopeptides, linking sequon recognition, cradle closure and catalysis during infant-gut glycan acquisition.

Abstract. Chiral halohydrins are valuable synthetic intermediates. Herein, we report an electroenzymatic sequential catalysis strategy for the site-selecti

Pliable connector molecules could be key to creating nanoparticle-based materials for photonics, chemical catalysis, medicine, and more.

Nature Synthesis, Published online: 27 October 2026; doi:10.1038/s44160-026-01175-5Substituted cyclohexanes are key motifs in drug discovery; therefore, stereoselective methods for their synthesis are valuable. However, the synthesis of thermodynamically disfavoured stereoisomers remains challenging. Now, a dual-ligand nickel system enables stereoselective three-component synthesis of substituted cyclohexanes, through Ni-catalysed 1,1-arylfunctionalization of substituted methylenecyclohexanes.