LightNews — News, ranked by scholars

Micah Etter, MD

@mettermd.bsky.social

the FRONTIER stroke trial was overall “negative,” but…

“In those given reperfusion therapies (thrombolysis or endovascular thrombectomy, or both) nerinetide was associated with improved favourable functional outcomes (adjusted odds ratio 1·84, 1·03–3·28)”

🤔🤔🤔

#Neurology #NeuroSky

Efficacy and safety of intravenous nerinetide initiated by paramedics in the field for acute cerebral ischaemia within 3 h of symptom onset (FRONTIER): a phase 2, multicentre, randomised, double-blind...

Prehospital nerinetide did not improve neurological functional outcomes in all patients with suspected ischaemic stroke in the mITT population. Nerinetide might benefit patients with acute ischaemic s...

www.thelancet.com

February 16, 2025 at 6:41 PM

RR Baliga MD, MBA

@rrbaliga.bsky.social

🚨 Stroke Research Update 🚨
Nerinetide 🧬 showed no overall benefit in acute ischemic stroke but may help reperfusion therapy patients ⏳🩸. Safe but needs further study! 🔬🧠 #Stroke youtu.be/p4X1n9VbCmA?... @americanheart.bsky.social @accintouch.bsky.social #CardioEd #MedEd #medtwitter #cardiotwitter

🧠💉 Nerinetide in Stroke: Hope or Hype? 🚑🔬

YouTube video by MasterMedFacts

youtu.be

February 23, 2025 at 2:07 PM

Krembil Brain Institute 🧠

@kbi-uhn.bsky.social

 📖✨ Congratulations to Dr. Michael Tymianski, Senior Scientist at UHN's Krembil Brain Institute, for having THREE (yes, three!) studies published simultaneously in The Lancet and Lancet Neurology!

🔗: linktr.ee/krembil

#AcuteIschemicStroke #AIS #BrainResearch #Nerinetide #StrokeResearch

February 24, 2025 at 3:19 PM

University Health Network

@uhn.ca

Breakthrough in stroke treatment!

#TeamUHN's Dr. Michael Tymianski has three studies published simultaneously in The Lancet & The Lancet Neurology, finding that neuroprotective drug nerinetide could help improve outcomes for stroke patients.

Learn more:
www.uhn.ca/corporate/ne...

February 19, 2025 at 9:19 PM

Centre for Advancing Health

@advancinghealth.bsky.social

Advancing Health's Jim Christenson has published results in The Lancet from his phase II clinical trial which evaluated the neuroprotective effects of nerinetide for stroke patients who received reperfusion therapies.

www.thelancet.com/journals/lan...

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March 10, 2025 at 10:22 PM

Research at UHN

@uhnresearch.ca

🧠 Stroke breakthrough—published in three Lancet papers!

Research from Dr. Michael Tymianski & team at UHN's Krembil Brain Institute finds nerinetide may help protect the brain when given before restoring blood flow after a #stroke.

Read more ➡️ www.uhnresearch.ca/news/protect...

February 18, 2025 at 3:49 PM

Claire Pomeroy

@drclairepomeroy.bsky.social

🧪🧠Assessment of tau protein may help predict outcomes & track treatment response after ischemic stroke, per study in Science Translational Medicine Science Magazine. Higher tau levels linked to worse injury; lower levels seen with full recanalization & nerinetide treatment: https://ow.ly/CaHX50Yw2Tq

"Brain-derived tau in blood tracked
trajectory of brain injury, predicting functional outcomes for up to 36 months." [CT scan showing a cross-section of the brain.]

March 23, 2026 at 11:25 PM

BehavEcolPapers

@behavecolpapers.bsky.social

Efficacy and Safety of Nerinetide in Acute Ischemic Stroke Patients: A Systematic Review, Meta‐Analysis and Meta Regression Br&Beh

Efficacy and Safety of Nerinetide in Acute Ischemic Stroke Patients: A Systematic Review, Meta‐Analysis and Meta Regression

Brain and Behavior, Volume 15, Issue 11, November 2025.

dlvr.it

November 15, 2025 at 9:20 AM

PulmCCM

@pulmccm.skystack.xyz

Good To Know: April 10, 2025 • Aspirin for sepsis, C. auris, CDC watching ceftriaxone, nerinetide for strokes, more

Good To Know: April 10, 2025

Aspirin for sepsis, C. auris, CDC watching ceftriaxone, nerinetide for strokes, more

www.pulmccm.org

November 24, 2025 at 8:18 PM

The Lancet Neurology

@thelancetneuro.bsky.social

Original research in the March issue:

🧠 Direct oral anticoagulants for cerebral venous thrombosis
💉 A meta-analysis of nerinetide for ischaemic stroke
🆕 A case series describing a new disease, autoinflammatory encephalopathy due to PTPN1 haploinsufficiency

🖱️ www.thelancet.com/issue/S1474-...

Cerebral venous thrombosis shown on a computed tomography angiography brain scan

February 20, 2025 at 10:10 AM

Centre for Advancing Health

@advancinghealth.bsky.social

📣 Publication alert! 📣

Advancing Health's Jim Christenson has published results in The Lancet from his phase II clinical trial which evaluated the neuroprotective effects of nerinetide for stroke patients who received reperfusion therapies.

www.thelancet.com/journals/lan...