Muscle contraction isn't a single event—it's a five-stage molecular cascade involving electricity, calcium, proteins, and energy. Unde…

#Calciumsignaling #Musclecontraction #Musclephysiology #Myosinactin #Neuromuscularjunction

#Calciumsignaling #Musclecontraction #Musclephysiology #Myosinactin …

This is sad. I met Dr. Fischbach when I was a postdoc; a project on regulation of #Agrin 's #splicing by #NOVA proteins at the #NeuromuscularJunction.

I knew nothing about the #NMJ at the time, and he taught me a lot.

I have fond memories of our collaboration 👇

www.pnas.org/doi/10.1073/...

From our latest issue 🆕 research from @uottawa.bsky.social demonstrating peripheral effects before motor neuron loss in the #SMA 2B/- mouse model. Read the #openaccess paper here: buff.ly/51H530o #spinalmuscularatrophy #neuromuscularjunction

#hiPSC #Senorimotor #Organoid
->Neural/Microglia/Vessel/Striated myofiber
->Modeling the impacts of #AmyotrophicLateralSclerosis variants (TDP43/SOD1/PFN1) on #NeuroMuscularJunction

To study Pericyte-NMJ crosstalk?

Brian Wainger lab #NatureComms 2021
www.nature.com/articles/s41...

In this work, we characterized the third Ig domain of human MuSK, a #cellsurface #receptor #protein #kinase critical for #neuromuscularjunction formation and stabilization.

Myasthenia Gravis: Autoimmune Neuromuscular Disorder, Symptoms, Diagnosis & Crisis Management
#MyastheniaGravis #Neurology #AutoimmuneDisease #VikaasShandily #NeuromuscularJunction

I am loving our chemistry... 🧪🧠🔬
#FlourescentFriday #fluorescenceFriday #iykyk #neuromuscularjunction #ALS #science #synapse #chemistry #happyfriday