#Noninvasively
everyone gets a tail tomorrow (happens painlessly and noninvasively):

A: feathers
B: fur
C: scales
D: bare skin
E: other
March 16, 2024 at 11:14 PM
Scientists trying to find a way to noninvasively diagnose a disease literally got asked by doctors—you know, the FIRST DO NO HARM people?—

“Why do you want to NOT cut women open to diagnose a disease, like why would you bother trying to find a way to not cut them open?”
September 10, 2025 at 6:14 AM
August 13, 2026 at 7:43 PM
Instant sepsis diagnosis via skin spectral imaging (palm or finger) and A.I. in a prospective cohort of >480 ICU patients
www.science.org/doi/10.1126/...
AI-powered skin spectral imaging enables instant sepsis diagnosis and outcome prediction in critically ill patients
AI-driven hyperspectral imaging can rapidly and noninvasively diagnose sepsis and predict mortality in critically ill patients.
www.science.org
July 18, 2025 at 6:57 PM
Ultrasound-based pacemaker noninvasively steadies the heart.

#science #medicine #news

www.lifescience.net/news/7450/ul...
Ultrasound-based pacemaker noninvasively steadies the heart
The new design could offer a surgery-free alternative to traditional cardiac implants.
www.lifescience.net
June 14, 2026 at 12:10 PM
A new approach to detect Alzheimer's simply, noninvasively, and inexpensively

"Neurovascular phase coherence is altered in Alzheimer’s disease"

academic.oup.com/braincomms/a...
Neurovascular phase coherence is altered in Alzheimer’s disease
Bjerkan et al. assessed the functioning of the neurovascular unit in Alzheimer’s disease through non-invasive measurements of brain electrical activity, br
academic.oup.com
February 3, 2025 at 12:39 AM
🧠 NEW PAPER: How do we capture excitability noninvasively in mood and emotion networks in the human brain? Here, we used real-time optimization to improve these measures!
@sparmi.bsky.social @stanfordpntlab.bsky.social @clinicalneuroph.bsky.social doi.org/10.1016/j.clinph.2025.02.261 1/7
Redirecting
doi.org
April 9, 2025 at 11:26 PM
Using PET imaging to noninvasively monitor the real-time effects of an antibody-drug conjugate on bladder #cancer tumors can inform dosing decisions to help optimize therapeutic benefits while avoiding toxicity.

Learn more in #ScienceAdvances: https://scim.ag/4pFC0B4
Nectin-4 PET for predicting enfortumab vedotin dose-response in urothelial carcinoma
Real-time PET imaging of Nectin-4 interactions unlocks tailored dosing strategies for precision cancer therapy.
scim.ag
January 13, 2026 at 7:48 PM
🩺Stanford Medicine:
‘Virtual biopsy’ lets clinicians analyze skin noninvasively without a surgical biopsy buff.ly/49DiJbD
‘Virtual biopsy’ lets clinicians analyze skin noninvasively
Stanford Medicine researchers develop a new imaging method to create a cell-by-cell reconstruction of skin or other tissue without taking a biopsy.
buff.ly
April 19, 2024 at 4:51 PM
Researchers have discovered how to use photoacoustic microscopy to noninvasively image a stent through the skin as a way to monitor its placement for any issues.

Check out the OPN story for more! bit.ly/4l7CyO2

#microscopy #biomedical #stent 💡⚛️🧪
July 31, 2025 at 1:17 PM
Researchers have developed a #DigitalTwin to noninvasively monitor heart failure. By modeling blood flow from CT scans, the system accurately predicts pulmonary artery pressure, matching results from invasive monitors in a 20-patient study.
#MedSky #MLSky 🫀
Digital twins for noninvasively measuring predictive markers of right heart failure - npj Digital Medicine
npj Digital Medicine - Digital twins for noninvasively measuring predictive markers of right heart failure
www.nature.com
August 26, 2025 at 2:07 PM
A noninvasive, CSF-specific MRI technique that enables detailed in vivo measurement of CSF mobility in humans, down to the level of perivascular spaces located around penetrating vessels

www.nature.com/articles/s41...
Region-specific drivers of CSF mobility measured with MRI in humans - Nature Neuroscience
Brain clearance mechanisms are challenging to visualize in humans. Using magnetic resonance imaging, the authors noninvasively mapped cerebrospinal fluid motion across the brain, showing region-specif...
www.nature.com
October 24, 2025 at 4:02 PM
In proof-of-concept work, scientists were able to leverage chirality to noninvasively use photoacoustic sensing to detect glucose levels in a patient.

The study could pave the way for diabetic patients to monitor their glucose levels without a finger prick.

Read the OPN story: bit.ly/3E3hwjR 💡🧪⚛️
March 26, 2025 at 7:03 PM
Ultrasound-based pacemaker noninvasively steadies the heart news.mit.edu/2026/ultraso...
The new design could offer a surgery-free alternative to traditional cardiac implants
June 2, 2026 at 5:32 PM
patients who intentionally self-extubate can often stay off the ventilator (eg using BiPAP or HFNC support).

when in doubt: stop all sedatives, support noninvasively, and watch really closely.

not ideal but this happens & often ends well 🤷‍♂️
a man wearing a sombrero sits in a classroom with his feet up and says i 'll allow it .
ALT: a man wearing a sombrero sits in a classroom with his feet up and says i 'll allow it .
media.tenor.com
March 5, 2025 at 5:00 PM
🧠 NEW PAPER: How do we capture excitability noninvasively in mood and emotion networks in the human brain? Here, we used real-time optimization to improve these measures!
@saraparmi @KellerStanfordU @ClinicalNeuroph doi.org/10.1016/j.clinph.2025.02.261 1/7
April 4, 2025 at 7:42 PM
March 2023 #Infographic in #Anesthesiology - Breathing Easy: Can Stress & Effort Be Measured Noninvasively in Mechanically Ventilated Patients? 🎨 ow.ly/osoa50UMabh
January 31, 2025 at 4:25 PM
🌍The World Picked Up Our Slack

Other countries went ahead and did the damn thing and proved that mifepristone was a GREAT way to treat fibroids noninvasively and with little side effects.
January 22, 2026 at 2:01 PM
this is wild and amazing! selective modulation of neurons in the ventral visual stream noninvasively, just by changing the visual input.

i've recently been saying that the senses are a powerful, overlooked BMI... the OG BMI designed by nature 😉 think of the possibilities!

arxiv.org/abs/2506.05633
Noninvasive precision modulation of high-level neural population activity via natural vision perturbations
Precise control of neural activity -- modulating target neurons deep in the brain while leaving nearby neurons unaffected -- is an outstanding challenge in neuroscience, generally approached using inv...
arxiv.org
June 26, 2025 at 5:42 PM
Hell yes! I hope someday we can do something similar noninvasively with TMS/Theta Burst. I definitely have anecdotes about restoring some non-useful vision after cortical/neuropathic blindness but not enough for a publishable case series yet.
July 17, 2026 at 1:14 AM
🧪 WAI grantee Paula Serres-Corral et al. developed a methodology for measuring oxytocin in feces, using #lions as a model species.

Because fecal samples are collected noninvasively, fecal oxytocin could be used to assess free-ranging #animalwelfare.

Read the paper👇
www.mdpi.com/2076-2615/15...
January 3, 2026 at 2:15 PM
New endometriosis tests could help patients get an accurate diagnosis quickly and noninvasively, speeding access to treatments and management strategies, including surgery, hormonal medications, and pelvic floor physical therapy.
New noninvasive endometriosis tests are on the rise
The tests could help people with the condition, who often suffer for many years undiagnosed.
www.technologyreview.com
October 21, 2025 at 1:24 PM
Here's hoping it's something that can be addressed noninvasively. Surgery sucks.
September 8, 2026 at 4:33 PM