#OSPC
LightNews LightNews
iaru-r1.bsky.social
The Amateur Radio and Amateur Satellite Devroom at FOSDEM 2027 has been confirmed. See you in Brussels!

#FOSDEM2027 #IARU-R1 #opensource #OSPC
October 24, 2026 at 5:02 PM
iaru-r1.bsky.social
Announcing the FOSDEM 2027 Amateur Radio and Amateur Satellite Developers Room Call for Papers: www.iaru-r1.org/2026/fosdem-...

See you in Brussels on the first weekend of february, as usual!

#opensource #hamradio #iaru-r1 #ospc
FOSDEM 2027: Amateur Radio DevRoom | International Amateur Radio Union (IARU)FOSDEM 2027: Amateur Radio DevRoom - International Amateur Radio Union (IARU)
www.iaru-r1.org
October 25, 2026 at 4:32 PM
travisjack.bsky.social
Full letter: travisjackstevens.com/news/delawar...

Sources: WHYY (Oct 6); OSPC SB 23/HB 450 town hall (Sept 25); DSHA 2023.
Delaware Just Rewrote the Rules for Building Homes. Here's What It Means for You. — Travis Jack Stevens for U.S. Senate
travisjackstevens.com
October 7, 2026 at 3:23 PM
drmylesgarvey.bsky.social
1943 Neuron:Mowing grass w/ 1000 old-school push carts (OSPC).

My 2026 neuron:Mowing grass 1 OSPC+wheels+engine:

Preprint: lnkd.in/eBM6y6MS
Hugging Face: lnkd.in/eBNz4Xqi

#llm #econometrics #neurotransmitters #math #receptors #brain #neuroscience #science
September 27, 2026 at 6:52 PM
linesforlife.bsky.social
Every conversation counts. Join us at OSPC, Oct. 19-21 in Bend, for real dialogue on suicide prevention, intervention, and postvention.

Register now: https://www.linesforlife.org/oregon-suicide-prevention-conference/
September 3, 2026 at 6:15 PM
zoonoses-journal.org
#Lymedisease diagnostics in dogs demand nuance.
The OspC BmpA based ICLF strip provides rapid antibody screening, but results must be read in context: clinical findings, exposure history, vaccination records, and confirmatory testing.

Check the article link - zoonoses-journal.org/index.php/20...
August 27, 2026 at 11:05 AM
zoonoses-journal.org
Check this article link - tinyurl.com/28rmyf8q
Development of a Colloidal Gold Immunochromatographic Strip for Rapid Serological Detection of Antibodies to Borrelia burgdorferi in Canines - Zoonoses Journal
The study introduces an OspC‑BmpA‑based ICLF strip as a rapid and straightforward serological tool for screening antibodies to Borrelia burgdorferi in dogs.
tinyurl.com
August 27, 2026 at 11:08 AM
bstevensonlab.bsky.social
Video of a recent presentation by Scarlet Shifflett, on "ospC: An essential protein in Lyme disease* transmission."

From this group, from the April 2026 meeting of the American Entomological Society

www.youtube.com/watch?v=lk2Z...

#MicroSky
www.youtube.com
August 11, 2026 at 2:27 PM
bstevensonlab.bsky.social
ospC diversity in Borrelia burgdorferi: different hosts are different niches

A report from 2004 that also found that OspC type U preferentially infected chipmunks

academic.oup.com/genetics/art...

#MicroSky
Table from the paper. The outer surface protein C (ospC) locus of the Lyme disease bacterium, Borrelia burgdorferi, is at least an order of magnitude more variable than other genes in the species. This variation is classified into 22 ospC major groups, 15 of which are found in the northeastern United States. The frequency distributions of ospC within populations suggest that this locus is under balancing selection. In multiple-niche polymor- phism, a type of balancing selection, diversity within a population can be maintained when the environment is heterogeneous and no one genotype has the highest fitness in all environments. Genetically different individuals within vertebrate species and different vertebrate species constitute diverse environments for B. burgdorferi. We examined four important host species of B. burgdorferi and found that the strains that infected each species had different sets of ospC major groups. We found no variation among conspecific hosts in the ospC major groups of their infecting strains. These results suggest multiple niches create balancing selection at the ospC locus.
August 10, 2026 at 6:56 PM
bstevensonlab.bsky.social
Diversity and host specificity of Borrelia burgdorferi’s outer surface protein C (ospC) alleles in synanthropic mammals, with a notable ospC allele U absence from mixed infections

Does OspC type U preferentially infect chipmunks? And exclude other types?

journals.asm.org/doi/epub/10....

#MicroSky
Figure 2 Heatmap showing ospC allele frequencies across host species (T. striatus, eastern chipmunk; S. carolinensis, eastern gray squirrel; Peromyscus, white-footed/deer mice; M. pennsylvanicus, eastern meadow vole; M. musculus, house mouse; M. mephitis, stripped skunk). Higher allele frequencies are redder and lower frequencies are bluer. Human infectious alleles (A, B, I, and K) are italicized and in bold font.
August 10, 2026 at 6:50 PM
africa.skyfleet.blue
RDC: avec plus de 75.000 observateurs électoraux, l'OSPC va se déployer sur toute la République pour les élections de décembre
RDC: avec plus de 75.000 observateurs électoraux, l'OSPC va se déployer sur toute la République pour les élections de décembre
L´organisation de la société civile pour la paix au Congo (OSPC ONGD) a clôturé ce dimanche 05 Novembre 2023 à Kinshasa, sa session de formation des formateurs électoraux.
actualite.cd
November 5, 2023 at 6:45 PM
africa.skyfleet.blue
RDC: L´organisation de la société civile pour la paix au Congo cloture sa session de formation des formateurs électoraux
RDC: L´organisation de la société civile pour la paix au Congo cloture sa session de formation des formateurs électoraux
L´organisation de la société civile pour la paix au Congo (OSPC ONGD) a clôturé ce dimanche 05 Novembre 2023 à Kinshasa, sa session de formation des formateurs électoraux.
actualite.cd
November 5, 2023 at 6:25 PM
bstevensonlab.bsky.social
Should be an interesting presentation.

The speaker was lead author on papers that deal with B. burgdorferi OspC alelles and infectivity

e.g. pubmed.ncbi.nlm.nih.gov/38099660/

#MicroSky
americanentosoc.bsky.social American Entomological Society @americanentosoc.bsky.social · Mar 31
Our next meeting is coming up Wednesday, April 22, 7pm Eastern Time! Join us in-person or via Zoom for a guest lecture on "ospC: An essential protein in Lyme disease transmission" by Scarlet Shifflett, PhD candidate in Entomology and Wildlife Ecology @udelaware.bsky.social. Send us a DM for details.
A gloved hand holds a live white-footed mouse by the scruff. There is an engorged blacklegged tick feeding on the mouse's face.
April 7, 2026 at 4:58 PM
bstevensonlab.bsky.social
Perhaps.
Need to study expression patterns of the multiple ospC loci. Are all functional?
February 6, 2026 at 12:11 AM
bstevensonlab.bsky.social
Comparative genomics of Borrelia lusitaniae

Complete genome sequences of three isolates. Each has very few plasmids. A most unusual feature is that their important cp26 plasmids are partially degraded dimers, carrying multiple, distinct ospC genes.

academic.oup.com/g3journal/ad...

#MicroSky
Comparative genomics of Borrelia lusitaniae
Abstract. Human Lyme disease is a frequent tick-borne human disease that is caused by several species in the Borrelia burgdorferi sensu lato (BBSL) clade o
academic.oup.com
February 5, 2026 at 4:22 PM
bstevensonlab.bsky.social
Gac Is a Transcriptional Repressor of the Lyme Disease Spirochete's OspC Virulence-Associated Surface Protein

Castro-Padovani, Saylor, Husted, Krusenstjerna, Jusufovic, and Stevenson
2023, J Bacteriol, 205:e0044022.
doi: 10.1128/jb.00440-22
pubmed.ncbi.nlm.nih.gov/36920207/
#MicroSky
(A) Electrophoretic mobility shift assay (EMSA) of labeled Ip89 ospC operator, without (−) and with (+) cytoplasmic extract from strain B31. The asterisk indicates shifted probe that was present only when borrelial extract was included, indicating presence of a DNA-binding component. Unbound DNA is indicated by “free.” Some labeled DNA probe remained in the wells of the gel. (B) Cytoplasmic extract from strain B31 was incubated with Ip89 ospC operator DNA affixed to beads, eluted with increasing concentrations of NaCl, and eluates were separated by SDS-polyacrylamide gel electrophoresis. Lanes are labeled with the concentration of NaCl used for that elution. The arrow indicated a protein band of 30 to 35 kDa that eluted in the 0.3 and 0.5 mM NaCl washes. (C) Amino acid sequence of GyrA and Gac (the two potential initiation methionines of Gac are indicated by boldface and underlining). Mass spectrometry identified nine unique peptides that all mapped to the Gac ORF. Peptides identified with high confidence are shaded green, and those with lower confidence are red. (D) Predicted structures of B. burgdorferi Gac and GyrA proteins, as determined by AlphaFold (https://alphafold.ebi.ac.uk). Both are consistent with the solved structures of B. burgdorferi Gac and the N-terminal domain of E. coli GyrA (https://www.rcsb.org/structure/4ckk).
November 7, 2025 at 3:51 PM
bstevensonlab.bsky.social
IgM Ab levels against Erp and OspC proteins in mice infected with B. burgdorferi for 11 months. (A) Averaged responses for all mice. Bars (L to R), ErpA, ErpL, ErpQ, and OspC. (B) Analysis of a representative mouse. Diamonds, ErpA; squares, ErpL; triangles, ErpQ; circles, OspC.
IgM Ab levels against Erp and OspC proteins in mice infected with B. burgdorferi for 11 months. (A) Averaged responses for all mice. Bars (L to R), ErpA, ErpL, ErpQ, and OspC. (B) Analysis of a representative mouse. Diamonds, ErpA; squares, ErpL; triangles, ErpQ; circles, OspC.
December 7, 2023 at 3:59 PM
cotesdesneiges.bsky.social
www.youtube.com/watch?v=osPc...
Un petit Thomas Croisière pour terminer la semaine !
Retour vers 1964 : Les Beatles contre de Funès
YouTube video by Thomas Croisiere : vive le cinéma
www.youtube.com
December 29, 2024 at 9:44 PM
americanentosoc.bsky.social
On April 1, AES representatives attended the Delaware Valley Science Fair to select winners of the 2026 Calvert Awards for young entomologists. We look forward to recognizing the winners at our April 22 meeting! We'll also enjoy a lecture on "ospC: An essential protein in Lyme disease transmission."
April 21, 2026 at 12:40 PM
americanentosoc.bsky.social
NEXT WEEK: Join us April 22 for a talk on "ospC: An essential protein in Lyme disease transmission" by Scarlet Shifflett, University of Delaware! We will also be awarding the Calvert Awards for the best insect-focused science projects exhibited at the Delaware Valley Science Fair.
📷: Solomon Hendrix
Close-up dorsal view of an adult female blacklegged tick, Ixodes scapularis.
April 15, 2026 at 2:00 PM
americanentosoc.bsky.social
Don't forget: Our next meeting is coming up on Wednesday, April 22! We'll be announcing the winners of the Calvert Award for young entomologists (grades 6-12) and enjoying a talk on "ospC: An essential protein in Lyme disease transmission" by Scarlet Shifflett.
April 7, 2026 at 1:06 PM
americanentosoc.bsky.social
Our next meeting is coming up Wednesday, April 22, 7pm Eastern Time! Join us in-person or via Zoom for a guest lecture on "ospC: An essential protein in Lyme disease transmission" by Scarlet Shifflett, PhD candidate in Entomology and Wildlife Ecology @udelaware.bsky.social. Send us a DM for details.
A gloved hand holds a live white-footed mouse by the scruff. There is an engorged blacklegged tick feeding on the mouse's face.
March 31, 2026 at 12:36 PM
scanoldhollywood.bsky.social
Johnny Mack Brown

Caption on the back of the publicity photo reads: "OSPC-810

Johnny Mack Brown, Universal's action hero, shows his leading lady, Jennifer Holt, how a husky adventure hero takes his screen heroine a-walking."
Johnny Mack Brown Caption on the back of the publicity photo reads: "OSPC-810 Johnny Mack Brown, Universal's action hero, shows his leading lady, Jennifer Holt, how a husky adventure hero takes his screen heroine a-walking."
November 17, 2024 at 1:09 AM
uniofnomi.bsky.social
It's really interesting this species of Borrelia encodes for multiple ospC genes. That B. lusitaniae can infect both reptiles and mammals may be a hint why this is the case.

Perhaps this sp. retained gene duplications that were lost in other Borrelia spp. - in other words, contains ancestral ospC?
February 5, 2026 at 9:29 PM