#OpenFold
🤖 AWS SageMaker JumpStart Speeds OpenFold3 Deployments with NVIDIA BioIR

AWS has put OpenFold3 preview on SageMaker JumpStart, but a deployable model still has to finish the work. The OpenFold Consortium and Columbia...

#ScienceBiology #AmazonAWS #InferenceOptimization #AI #AIPulse
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www.synestesia.uk
November 15, 2026 at 10:34 AM
OpenFold3 structure prediction model lands on Amazon SageMaker JumpStart. AWS adds the OpenFold Consortium's all-atom model to its managed catalog, targeting drug discovery teams that lack GPU plumbing.
OpenFold3 structure prediction model lands on Amazon SageMaker JumpStart - GenAInews
AWS adds the OpenFold Consortium's all-atom model to its managed catalog, targeting drug discovery teams that lack GPU plumbing.
genainews.tech
November 14, 2026 at 8:57 AM
We are still exploring RFD4-Proteina, but, we also wanted to highlight the collaboration among the protein design community, including the Institute for Protein Design, NVIDIA, Rosetta Commons, and the OpenFold Consortium, that led to the open-source model’s development and release.
zurl.co/4KSpO
October 23, 2026 at 2:57 PM
Developed by the Institute for Protein Design (IPD) in collaboration with NVIDIA, and supported by Rosetta Commons and The OpenFold Consortium, RFD4-Proteina is now publicly available through the Rosetta Commons GitHub organization.
October 21, 2026 at 5:13 PM
we need some of the medium sized antrhopic or openAI customers to get together and do the LLM version of openfold.io
OpenFold: Open AI Infrastructure for Biology and Drug Discovery
OpenFold is a non-profit consortium building free, open-source AI tools for structural biology and drug discovery, trained, auditable, and available to everyone.
openfold.io
September 24, 2026 at 2:17 PM
the origin story of openfold was people getting really annoyed that deepmind didnt release weights or training code for Alphafold3
September 24, 2026 at 2:18 PM
I recall about ~3 months ago, claude was struggling to converting openfold weights to work inside alphafold3, I had to babysit it each step of the way. This is the session I explicity opted to share, when it asked. Now it can do it with single prompt. 🤷
September 18, 2026 at 11:03 AM
granite-speech-4.1-2b, kanana-2-30b-a3b-instruct, and OpenFold3 models now available on Amazon SageMaker JumpStart

BM's granite-speech-4.1-2b, Kakao's kanana-2-30b-a3b-instruct, and the OpenFold Consortium's OpenFold3 models are now available on Amazon SageM...

#AWS #AmazonSagemakerJumpstart #Aiml
granite-speech-4.1-2b, kanana-2-30b-a3b-instruct, and OpenFold3 models now available on Amazon SageMaker JumpStart
BM's granite-speech-4.1-2b, Kakao's kanana-2-30b-a3b-instruct, and the OpenFold Consortium's OpenFold3 models are now available on Amazon SageMaker JumpStart, expanding the portfolio of foundation models available to AWS customers. These three models bring specialized capabilities spanning multilingual speech recognition, bilingual agentic AI, and biomolecular structure prediction, enabling customers to deploy high-performance, scalable AI solutions on AWS infrastructure. These models address different enterprise AI challenges with specialized capabilities: granite-speech-4.1-2b is purpose-built for multilingual automatic speech recognition (ASR) and bidirectional speech translation (AST) across English, French, German, Spanish, Portuguese, and Japanese. This compact 2B-parameter speech-language model delivers a word error rate of 5.33% with a real-time factor of ~231, making it one of the most efficient ASR models in its class. Released under Apache 2.0, it integrates seamlessly into enterprise voice workflows for transcription, translation, and audio processing at scale. kanana-2-30b-a3b-instruct excels in bilingual Korean-English instruction following and agentic AI workflows. Developed by Kakao, it adopts a cutting-edge architecture featuring Multi-head Latent Attention (MLA) and Mixture-of-Experts (MoE), activating only 3B of its 30B total parameters per forward pass for superior throughput. Post-trained with supervised fine-tuning and reinforcement learning, it supports up to 128K tokens via YaRN scaling and is designed to function as an AI collaborator that understands context and acts proactively. OpenFold3 provides all-atom biomolecular complex structure prediction for proteins, DNA, RNA, and small-molecule ligands. Developed by the OpenFold Consortium and the AlQuraishi Lab at Columbia University, this diffusion-based model extends structure prediction beyond single proteins to model multi-chain complexes and heterogeneous biomolecular interactions. It supports computer-aided drug design and is applicable across academic and pharmaceutical research labs. With SageMaker JumpStart, customers can deploy any of these models with just a few clicks to address their specific AI use cases. To get started with these models, navigate to the SageMaker JumpStart model catalog in the SageMaker console or use the SageMaker Python SDK to deploy the models to your AWS account. For more information about deploying and using foundation models in SageMaker JumpStart, see the https://docs.aws.amazon.com/sagemaker/latest/dg/studio-jumpstart.html.
aws.amazon.com
September 14, 2026 at 6:05 PM
granite-speech-4.1-2b, kanana-2-30b-a3b-instruct, and OpenFold3 models now available on Amazon SageMaker JumpStart
BM's granite-speech-4.1-2b, Kakao's kanana-2-30b-a3b-instruct, and the OpenFold Consortium's OpenFold3 models are now available on Amazon SageMaker JumpStart, expanding the portfolio of foundation models available to AWS customers. These three models bring specialized capabilities spanning multilingual speech recognition, bilingual agentic AI, and biomolecular structure prediction, enabling customers to deploy high-performance, scalable AI solutions on AWS infrastructure. These models address different enterprise AI challenges with specialized capabilities: granite-speech-4.1-2b is purpose-built for multilingual automatic speech recognition (ASR) and bidirectional speech translation (AST) across English, French, German, Spanish, Portuguese, and Japanese. This compact 2B-parameter speech-language model delivers a word error rate of 5.33% with a real-time factor of ~231, making it one of the most efficient ASR models in its class. Released under Apache 2.0, it integrates seamlessly into enterprise voice workflows for transcription, translation, and audio processing at scale. kanana-2-30b-a3b-instruct excels in bilingual Korean-English instruction following and agentic AI workflows. Developed by Kakao, it adopts a cutting-edge architecture featuring Multi-head Latent Attention (MLA) and Mixture-of-Experts (MoE), activating only 3B of its 30B total parameters per forward pass for superior throughput. Post-trained with supervised fine-tuning and reinforcement learning, it supports up to 128K tokens via YaRN scaling and is designed to function as an AI collaborator that understands context and acts proactively. OpenFold3 provides all-atom biomolecular complex structure prediction for proteins, DNA, RNA, and small-molecule ligands. Developed by the OpenFold Consortium and the AlQuraishi Lab at Columbia University, this diffusion-based model extends structure prediction beyond single proteins to model multi-chain complexes and heterogeneous biomolecular interactions. It supports computer-aided drug design and is applicable across academic and pharmaceutical research labs. With SageMaker JumpStart, customers can deploy any of these models with just a few clicks to address their specific AI use cases. To get started with these models, navigate to the SageMaker JumpStart model catalog in the SageMaker console or use the SageMaker Python SDK to deploy the models to your AWS account. For more information about deploying and using foundation models in SageMaker JumpStart, see the Amazon SageMaker JumpStart documentation.
dlvr.it
September 14, 2026 at 6:07 PM
🆕 Amazon SageMaker JumpStart now offers BM's granite-speech-4.1-2b, Kakao's kanana-2-30b-a3b-instruct, and OpenFold3 models for multilingual ASR, bilingual AI, and biomolecular structure prediction. Deploy with ease to tackle enterprise AI challenges.

#AWS #AmazonSagemakerJumpstart #Aiml
granite-speech-4.1-2b, kanana-2-30b-a3b-instruct, and OpenFold3 models now available on Amazon SageMaker JumpStart
BM's granite-speech-4.1-2b, Kakao's kanana-2-30b-a3b-instruct, and the OpenFold Consortium's OpenFold3 models are now available on Amazon SageMaker JumpStart, expanding the portfolio of foundation models available to AWS customers. These three models bring specialized capabilities spanning multilingual speech recognition, bilingual agentic AI, and biomolecular structure prediction, enabling customers to deploy high-performance, scalable AI solutions on AWS infrastructure. These models address different enterprise AI challenges with specialized capabilities: granite-speech-4.1-2b is purpose-built for multilingual automatic speech recognition (ASR) and bidirectional speech translation (AST) across English, French, German, Spanish, Portuguese, and Japanese. This compact 2B-parameter speech-language model delivers a word error rate of 5.33% with a real-time factor of ~231, making it one of the most efficient ASR models in its class. Released under Apache 2.0, it integrates seamlessly into enterprise voice workflows for transcription, translation, and audio processing at scale. kanana-2-30b-a3b-instruct excels in bilingual Korean-English instruction following and agentic AI workflows. Developed by Kakao, it adopts a cutting-edge architecture featuring Multi-head Latent Attention (MLA) and Mixture-of-Experts (MoE), activating only 3B of its 30B total parameters per forward pass for superior throughput. Post-trained with supervised fine-tuning and reinforcement learning, it supports up to 128K tokens via YaRN scaling and is designed to function as an AI collaborator that understands context and acts proactively. OpenFold3 provides all-atom biomolecular complex structure prediction for proteins, DNA, RNA, and small-molecule ligands. Developed by the OpenFold Consortium and the AlQuraishi Lab at Columbia University, this diffusion-based model extends structure prediction beyond single proteins to model multi-chain complexes and heterogeneous biomolecular interactions. It supports computer-aided drug design and is applicable across academic and pharmaceutical research labs. With SageMaker JumpStart, customers can deploy any of these models with just a few clicks to address their specific AI use cases. To get started with these models, navigate to the SageMaker JumpStart model catalog in the SageMaker console or use the SageMaker Python SDK to deploy the models to your AWS account. For more information about deploying and using foundation models in SageMaker JumpStart, see the Amazon SageMaker JumpStart documentation.
aws.amazon.com
September 14, 2026 at 6:11 PM
The Australian Structural Biology Computing Community is excited to host Tom Goddard from UCSF ChimeraX @chimerax.ucsf.edu on Wed 16th Sept. He will present: Predicting atomic structures with OpenFold 3 and ChimeraX—a practical look at predicting, visualising and exploring protein structures.
Welcome | Australian Structural Biology Computing
This website is a virtual meeting place and hub for all users of **computing for structural biology research in Australia**. This is a collective community effort. It can be what...
australian-structural-biology-computing.github.io
September 14, 2026 at 3:46 AM
September 10, 2026 at 6:25 PM
The OpenFold team released the @openbind.bsky.social nbind.bsky.social model a few weeks ago. As we use AF3 for large co-folding runs, we still feel the gap in memory efficiency between OF3 and AF3. For this reason, we adapted the AF3 code to use the openbind weights
openbind.uk/news/blog-op...
Blog: OpenBind-0: Advancing Open Molecular Structure Prediction | openbind.uk
Introducing OpenBind-0, a fully open molecular structure prediction model. This post presents the model, its performance, and new benchmark data that highli ...
openbind.uk
September 8, 2026 at 3:09 PM
OpenFold 3 Pushes Protein AI From Prediction to Design

Protein AI has moved past folding. Now it designs drugs, complexes, and DNA interactions.

#AI #AIResearch #MachineLearning

https://autonainews.com/openfold-3-pushes-protein-ai-from-prediction-to-design/
OpenFold 3 Pushes Protein AI From Prediction to Design
Protein structure prediction has quietly outgrown its own origin story. AlphaFold2 solved the single-protein folding problem; what's happening now is harder and more consequential, AI models predicti…
autonainews.com
August 27, 2026 at 12:04 PM
If Linux (for OS) is any model, OpenFold3 wants to become the standard for structural biology in academia & industry alike. Ambitious—but necessary. #OpenSource https://www.maffulli.net/2025/10/30/openfold3-open-source-replacement-alphafold/ #ai
OpenFold3 is an Open Source foundation model competing with the proprietary AlphaFold - ][ Stefano Maffulli
Reposted OpenFold Consortium Releases Preview of OpenFold3: An Open-Source Foundation Model for Structure Prediction of Proteins, Nucleic Acids, and Drugs (businesswire.com) It was bound to …
www.maffulli.net
November 3, 2025 at 8:47 PM
Built with PyTorch, containerised, deployable at scale. OpenFold3 is designed to plug into your stack—Open Source usability matters. #TechForGood https://www.maffulli.net/2025/10/30/openfold3-open-source-replacement-alphafold/ #ai #OpenSource
OpenFold3 is an Open Source foundation model competing with the proprietary AlphaFold - ][ Stefano Maffulli
Reposted OpenFold Consortium Releases Preview of OpenFold3: An Open-Source Foundation Model for Structure Prediction of Proteins, Nucleic Acids, and Drugs (businesswire.com) It was bound to …
www.maffulli.net
October 31, 2025 at 8:53 AM
The Apache 2.0 license means you can test, train, adapt and build on OpenFold3—no “industry use only” caveats. Open governance FTW. 🙌 #OpenSource #BioTech https://www.maffulli.net/2025/10/30/openfold3-open-source-replacement-alphafold/ #ai
OpenFold3 is an Open Source foundation model competing with the proprietary AlphaFold - ][ Stefano Maffulli
Reposted OpenFold Consortium Releases Preview of OpenFold3: An Open-Source Foundation Model for Structure Prediction of Proteins, Nucleic Acids, and Drugs (businesswire.com) It was bound to …
www.maffulli.net
October 31, 2025 at 7:53 AM
OpenFold Consortium Releases Preview of OpenFold3: An Open-Source Foundation Model for Structure Prediction of Proteins, Nucleic Acids, and Drugs
www.businesswire.com/news/home/20...

(Old-ish news for Bluesky, but getting back into the Bsky groove; expect more good things to come.)
www.businesswire.com
November 26, 2025 at 1:40 AM
OpenFold website:
openfold.io
OpenFold Consortium
description
openfold.io
November 27, 2024 at 7:37 PM
Protein structure prediction is going to transform biology and medicine. From AlphaFold's breakthrough to a Nobel Prize, the future is clear: structure drives innovation. #OpenFold is democratizing tools to empower researchers everywhere. Come join the movement!
www.businesswire.com/news/home/20...
OpenFold AI Research Consortium Welcomes Six New Members: Astex, Biogen, Congruence, Polaris Quantum, Psivant, and SandboxAQ
The non-profit consortium is developing publicly accessible advanced AI-based drug discovery software tools.
www.businesswire.com
November 27, 2024 at 7:22 PM
It’s a terrible disappointment isn’t it? 😔 it could have done so much good. Well- I’ll keep backing Openfold and encouraging scientists to use that. I’m predicting it a number of law suits where Google chase people. They have a number of patents where they try to reach through AF so I’m wary.
May 8, 2024 at 10:29 PM
Exciting talk by Mohammed AlQuraishi (Openfold) - they saved the best till last! Lorne protein. I love his optimism about how quickly this space is moving forward.🧶🧬
February 7, 2024 at 7:30 AM
We are doing similar approaches here in Oz. Are you still using the original MSA step or have you looked into Openfold?
January 10, 2024 at 10:46 PM