Results from the demonstrate that low-dose radiotherapy combined with PD-1 blockade promotes durable survival in advanced NSCLC by inducing antitumor neutrophil programming.
#STTT #OpenAccess: doi.org/10.1038/s413...
#LungCancer #Radiotherapy #PD1Blockade #Immunotherapy
#STTT #OpenAccess: doi.org/10.1038/s413...
#LungCancer #Radiotherapy #PD1Blockade #Immunotherapy
May 12, 2026 at 1:50 PM
Results from the demonstrate that low-dose radiotherapy combined with PD-1 blockade promotes durable survival in advanced NSCLC by inducing antitumor neutrophil programming.
#STTT #OpenAccess: doi.org/10.1038/s413...
#LungCancer #Radiotherapy #PD1Blockade #Immunotherapy
#STTT #OpenAccess: doi.org/10.1038/s413...
#LungCancer #Radiotherapy #PD1Blockade #Immunotherapy
IL-7 agonist #EfineptakinAlfa (NT-I7) reshapes the #TumorMicroenvironment, expanding T, B, DC, and stem-like CD8 T cells while inducing TLS-like aggregates enriched in PD-L1, suggesting synergy with #PD1blockade.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
March 13, 2026 at 1:00 PM
IL-7 agonist #EfineptakinAlfa (NT-I7) reshapes the #TumorMicroenvironment, expanding T, B, DC, and stem-like CD8 T cells while inducing TLS-like aggregates enriched in PD-L1, suggesting synergy with #PD1blockade.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
Scientists identify #IGF2BP1 as a driver of #ImmuneEvasion in C5 #OvarianCancer, suppressing IFN‑γ–IRF1–MHC‑I signaling and T‑cell infiltration; its inhibition restores #antitumor immunity and boosts #PD1blockade. @unihalle.bsky.social
#OpenAccess in #STTT: doi.org/10.1038/s413...
#OpenAccess in #STTT: doi.org/10.1038/s413...
Inhibition of RNA-binding proteins enhances immunotherapy in ovarian cancer - Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy - Inhibition of RNA-binding proteins enhances immunotherapy in ovarian cancer
doi.org
December 30, 2025 at 2:30 PM
Scientists identify #IGF2BP1 as a driver of #ImmuneEvasion in C5 #OvarianCancer, suppressing IFN‑γ–IRF1–MHC‑I signaling and T‑cell infiltration; its inhibition restores #antitumor immunity and boosts #PD1blockade. @unihalle.bsky.social
#OpenAccess in #STTT: doi.org/10.1038/s413...
#OpenAccess in #STTT: doi.org/10.1038/s413...