#PETMRI
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FAPI PET/MRI in #Endometriosis: A Practical Approach to Mapping Complex Disease Beyond Standard Pelvic #MRI by Philipp Schindler, MD; et al. (University Hospital Münster, Germany).

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#PETMRI #MolecularImaging #RadSky #WomensHealth
Although endometriosis is often described as a pelvic disease, daily practice shows that the questions relevant to patients and surgeons are broader: - Where is the active disease? - Which organs or compartments are involved? - Which lesions could change the operative strategy? The authors share their experience with fibroblast activation protein (FAP)-targeted PET/MRI, showing how molecular information can provide a practical guide for MRI interpretation, particularly in anatomically challenging areas. Clinical benefit: Better visualization of complex, multifocal, peritoneal, tubo-ovarian, and extrapelvic diseases, which may improve preoperative planning and patient counseling. Operational benefit: An MRI-first, PET-guided second read can translate molecular hot spots into a structured, #Enzian-based map for the multidisciplinary team. Financial and societal perspective: Earlier and more targeted diagnoses could reduce the need for repeated consultations, duplicate tests, unnecessary procedures, and lost productivity in a disease that is often not diagnosed until years after the onset of symptoms. Images: Patient presenting with menstrual cycle-dependent right shoulder pain. (2A) MIP PET images demonstrate abnormal tracer uptake in the right diaphragm, bilateral round ligaments, the peritoneum surrounding both ovaries, and the left fallopian tube (indicated by arrows). On fused PET/MRI, a T2-hyperintense lesion with focal tracer uptake is identified inferior to the right hemidiaphragm, consistent with diaphragmatic endometriosis (arrows, 2B). Subsequent laparoscopy confirmed extensive pelvic endometriosis and diaphragmatic implants (2C).
September 29, 2026 at 7:52 AM
stevenalleyn.ca
Antimatter is not science-fiction and modern medicine uses it for imaging (the P in PETMRI is Positron)
katelynburns.com Katelyn Burns @katelynburns.com · Sep 4
Tell me a fun fact.
September 5, 2026 at 4:29 AM
asfnr.bsky.social
Register now for a free ASFNR-ASNR webinar on July 9 at 1:00 pm ET (note DiFFeReNT time)!
“Seeing The Invisible: PET/MRI Advancements in Brain Tumor Evaluation”
Register: ow.ly/kWgK50WgMyI
#PetMri
#beyondBOLD #NeuroRadiology #MedEd
June 28, 2025 at 12:03 AM
antjehellwich.bsky.social
On #WorldParkinsonsDay, I'd like to highlight “ASL as a Potential Biomarker in Imaging of #Neurodegenerative Disorders” by Prof. Sandhya Mangalore, et al. (Nat. Inst. of Mental Health and Neurosciences, India).

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#NeuroSky #MRI #PETMRI
Neuroimaging findings in neurodegenerative disorders are often complex, as imaging findings in patients with mild signs and symptoms are frequently subtle and ambiguous. In many cases, by the time imaging findings become obvious, patients have already manifested clinically, and the diagnosis is already established or at least highly suspected. The radiation-free PCASL-MRI approach helps, based on the perfusion profile, to achieve an early and accurate diagnosis prior to gross morphological alterations when standardized with PET in simultaneous PET-MRI acquisitions. PCASL and PET changes preceded structural atrophy patterns and could aid in establishing early clinical diagnosis. The combination of PET and PCASL boosted the sensitivity of structural MRI and PET by synergistically diagnosing disease conditions. The synergistic effect of PCASL and FDOPA boosted the sensitivity and specificity in classifying disorders with dopaminergic deficit into IPD/APD phenotypes without the need for additional FDG PET or D2-receptor imaging. The authors highlight the role of simultaneous PCASL PET-MRI in the workup of complex neurodegenerative conditions with FDG in centers that do not have a cyclotron facility for producing non-FDG tracers. In clear-cut clinical neurodegenerative disorders, where structural changes are equivocal, an additional PCASL sequence can help in early diagnosis without the need for PET studies.
April 11, 2026 at 3:00 PM
camrt.ca
‪
IT’S FREE EDUCATION FRIDAY!

Today we are taking a look at:
CAMRT 2023: PETMRI at UHN: Current Status and Future Perspective; 2) Imaging Neurosurgery

Presented by Jin Huang & Stephanie Holowka

Add it to your cart and go through the “purchase” process.

Link: https://ow.ly/RBoF50YCpCg
April 24, 2026 at 1:01 PM
puritanuj.bsky.social
What are the 6 ways to quantify [18F]NaF PET-CT imaging? #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #BoneHealth #HealthyBones #BoneResearch #ImagingInnovation #EarlyDetection #StrongBones
Puri T, Blake GM, Frost ML, Siddique M, Moore AE, Marsden PK, Cook GJ, Fogelman I, Curran KM. Comparison of six quantitative methods for the measurement of bone turnover at the hip and lumbar spine using 18F-fluoride PET-CT. Nucl Med Commun. 2012 Jun;33(6):597-606. doi: 10.1097/MNM.0b013e3283512adb. PMID: 22441132. Puri, T. (2011). Bone metabolism measured with six quantification methods using 18F-PET, World Molecular Imaging Congress. In World Molecular Imaging Congress, 7-10 Sept 2011, San Diego, California, USA. https://lnkd.in/e7XvCEaR
January 12, 2025 at 8:58 AM
puritanuj.bsky.social
What are precision errors, and what do they mean in [18F]NaF PET imaging? #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #boneimaging
doi: 10.21037/qims.2018.01.02
Blake GM, Puri T, Siddique M, Frost ML, Moore AEB, Fogelman I. Site specific measurements of bone formation using [18F] sodium fluoride PET/CT. Quant Imaging Med Surg. 2018 Feb;8(1):47-59. doi: 10.21037/qims.2018.01.02. PMID: 29541623; PMCID: PMC5835654.
January 10, 2025 at 9:54 AM
puritanuj.bsky.social
When using [18F]NaF PET, which is the most effective parameter to assess treatment response? #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #ImagingInnovation doi: 10.21037/qims.2018.01.02
Blake GM, Puri T, Siddique M, Frost ML, Moore AEB, Fogelman I. Site specific measurements of bone formation using [18F] sodium fluoride PET/CT. Quant Imaging Med Surg. 2018 Feb;8(1):47-59. doi: 10.21037/qims.2018.01.02. PMID: 29541623; PMCID: PMC5835654.
January 9, 2025 at 9:17 AM
puritanuj.bsky.social
[18F]NaF vs [18F]FDG PET-CT for Detection of Skull-Base Invasion and Osseous Metastases in Nasopharyngeal Carcinoma #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #cancer doi: 10.1155/2018/8271313
Zhang Y, Chen Y, Huang Z, Zhang L, Wan Q, Lei L. Comparison of 18F-NaF PET/CT and 18F-FDG PET/CT for Detection of Skull-Base Invasion and Osseous Metastases in Nasopharyngeal Carcinoma. Contrast Media Mol Imaging. 2018 Sep 5;2018:8271313. doi: 10.1155/2018/8271313. PMID: 30254551; PMCID: PMC6145050.
January 8, 2025 at 10:32 AM
puritanuj.bsky.social
[18F]FDG+[18F]NaF PET-CT vs [18F]FDG PET-CT imaging for detection of malignancy #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #CancerResearch #BoneRemodeling doi: 10.1007/s00259-011-1971-1
Lin, F.I., Rao, J.E., Mittra, E.S. et al. Prospective comparison of combined 18F-FDG and 18F-NaF PET/CT vs. 18F-FDG PET/CT imaging for detection of malignancy. Eur J Nucl Med Mol Imaging 39, 262–270 (2012).
January 7, 2025 at 10:09 AM
puritanuj.bsky.social
Cocktail [18F]NaF and [18F]FDG PET-CT Scan for Evaluation of Malignancy #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging doi: 10.2967/jnumed.108.058339
Iagaru A, Mittra E, Yaghoubi SS, Dick DW, Quon A, Goris ML, Gambhir SS. Novel strategy for a cocktail 18F-fluoride and 18F-FDG PET/CT scan for evaluation of malignancy: results of the pilot-phase study. J Nucl Med. 2009 Apr;50(4):501-5. doi: 10.2967/jnumed.108.058339. Epub 2009 Mar 16. PMID: 19289439.
January 5, 2025 at 10:46 AM
puritanuj.bsky.social
[18F]NaF PET Ki is considered a marker of bone formation, then, why is it used to study cancer-related bone metastases? #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging www.linkedin.com/feed/update/...
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January 4, 2025 at 11:30 AM
puritanuj.bsky.social
When to perform [18F]NaF PET scan for estimating bone metabolism post-treatment? #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging doi: 10.1210/jcem.79.6.7989477
Garnero P, Shih WJ, Gineyts E, Karpf DB, Delmas PD. Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment. J Clin Endocrinol Metab (1994) 79(6):1693–700. doi: 10.1210/jcem.79.6.7989477
January 2, 2025 at 11:22 AM
puritanuj.bsky.social
Happy New Year to All #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #BoneHealth #HealthyBones #Osteoarthritis #BoneResearch #ImagingInnovation #cancer #prostatecancer #breastcancer #metastasis
January 1, 2025 at 10:30 AM
puritanuj.bsky.social
Detecting Bone Spread in Bladder Cancer - [18F]NaF PET-CT vs 99mTc-MDP SPECT-CT #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #cancer #bonecancer
doi: 10.1097/RLU.0b013e31828da5cc
December 31, 2024 at 10:46 AM
puritanuj.bsky.social
[18F]NaF PET as a Way to Track Treatment Response in Bone Metastases from Prostate Cancer #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging
#cancer #prostat #prostatecancer DOI: 10.1186/2191-219X-1-4
Cook, G.J., Parker, C., Chua, S. et al. 18F-fluoride PET: changes in uptake as a method to assess response in bone metastases from castrate-resistant prostate cancer patients treated with 223Ra-chloride (Alpharadin). EJNMMI Res 1, 4 (2011). https://lnkd.in/es9x4ckh
December 30, 2024 at 11:36 AM
puritanuj.bsky.social
[18F]NaF vs [18F]FDG PET-CT in Detecting Occult Metastatic Disease in Prostate Cancer #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #cancer #prostatecancer doi: 10.1053/j.semnuclmed.2014.07.008
Jadvar H, Desai B, Conti PS. Sodium 18F-fluoride PET/CT of bone, joint, and other disorders. Semin Nucl Med. 2015 Jan;45(1):58-65. doi: 10.1053/j.semnuclmed.2014.07.008.
December 29, 2024 at 5:10 PM
puritanuj.bsky.social
[18F]FDG vs [18F]NaF PET-CT in breast cancer with bone metastases #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #ImagingInnovation
doi: 10.3892/ol.2024.14679
Hu H, Hu X, Liang Z, Yang W, Li S, Li D, Cai J. Diagnostic performance of 18F‑FDG PET/CT vs. 18F‑NaF PET/CT in breast cancer with bone metastases: An indirect comparative meta‑analysis. Oncol Lett. 2024 Sep 12;28(5):546. doi: 10.3892/ol.2024.14679. PMID: 39319212; PMCID: PMC11420642.
December 28, 2024 at 1:58 PM
puritanuj.bsky.social
Correlation between [18F]NaF PET and bone histomorphometry in renal osteodystrophy #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging doi: 10.1016/j.bone.2020.115267
Aaltonen L, Koivuviita N, Seppänen M, Tong X, Kröger H, Löyttyniemi E, Metsärinne K. Correlation between 18F-Sodium Fluoride positron emission tomography and bone histomorphometry in dialysis patients. Bone. 2020 May;134:115267. doi: 10.1016/j.bone.2020.115267. Epub 2020 Feb 11. PMID: 32058018.
December 26, 2024 at 9:43 AM
puritanuj.bsky.social
Role of [18F]NaF PET-CT in Diagnosing Bone Metastases #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #cancer #metastases #bone doi: 10.1016/j.jbo.2015.08.002
Araz M, Aras G, Küçük ÖN. The role of 18F-NaF PET/CT in metastatic bone disease. J Bone Oncol. 2015 Sep 16;4(3):92-7. doi: 10.1016/j.jbo.2015.08.002. PMID: 26587375; PMCID: PMC4648995.
December 24, 2024 at 11:23 AM
puritanuj.bsky.social
[18F]NaF PET for Detecting Bone Metastases in Breast Cancer #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #cancer #breastcancer doi.org/10.1007/s002...
Petrén-Mallmin, M., Andréasson, I., Ljunggren, Ö. et al. Skeletal metastases from breast cancer: uptake of 18F-fluoride measured with positron emission tomography in correlation with CT. Skeletal Radiol 27, 72–76 (1998). https://doi.org/10.1007/s002560050340
December 23, 2024 at 8:03 AM
puritanuj.bsky.social
[18F]NaF PET in differentiated thyroid carcinoma
#18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #BoneHealth #BoneResearch #BoneImaging #BoneRemodeling doi: 10.1259/bjr.20130444
Ota N, Kato K, Iwano S, Ito S, Abe S, Fujita N, et al. Comparison of 18F-fluoride PET/CT, 18F-FDG PET/CT and bone scintigraphy (planar and SPECT) in detection of bone metastases of differentiated thyroid cancer: a pilot study. Br J Radiol 2014;87:20130444.
December 21, 2024 at 9:38 AM
puritanuj.bsky.social
Special Issue Information (Submission Deadline: 20 May 2025) #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #BoneHealth #BoneResearch #BoneImaging #BoneRemodeling #EarlyDetection www.mdpi.com/journal/jcm/...
December 20, 2024 at 9:25 AM
puritanuj.bsky.social
[18F]NaF PET for Detecting Bone Spread in Head & Neck Cancer #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging #BoneHealth #BoneResearch #ImagingInnovation doi: 10.2967/jnumed.112.104893
Chan SC, Wang HM, Ng SH, Hsu CL, Lin YJ, Lin CY, Liao CT, Yen TC. Utility of 18F-fluoride PET/CT and 18F-FDG PET/CT in the detection of bony metastases in heightened-risk head and neck cancer patients. J Nucl Med. 2012 Nov;53(11):1730-5. doi: 10.2967/jnumed.112.104893. Epub 2012 Sep 7. PMID: 22961077.
December 19, 2024 at 11:01 AM
puritanuj.bsky.social
Shoulder Pain Mystery Solved with [18F]NaF PET #18FNaF #nucmed #molrad #nuclearmedicine #nuclearradiology #molecularimaging #petct #petmri #precisionmedicine #precisionimaging doi: 10.1259/bjr.20170741
Usmani S, Marafi F, Esmail A, Ahmed N. Initial experience with 18F-sodium fluoride (NaF) PET-CT: a viable functional biomarker in symptomatic Os acromiale. Br J Radiol. 2018 Apr;91(1084):20170741. doi: 10.1259/bjr.20170741. Epub 2018 Jan 12. PMID: 29293370; PMCID: PMC5966011.
December 18, 2024 at 10:48 AM