#Pioglitazone
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April 29, 2025 at 8:50 PM
been so much hungrier since starting on pioglitazone
August 9, 2025 at 3:15 AM
I have to be the hottest girl taking experimental trаnny medication for some reason
March 5, 2026 at 5:27 AM
anyone got any experience with pioglitazone
March 15, 2026 at 2:51 AM
thinking about her again (pioglitazone)
August 5, 2025 at 4:22 PM
Finally got my doctor to up me to the max dose of Actos (pioglitazone is the generic). It lowers blood sugar by telling your body to make more new extra sugar sensitive fat cells to store glucose in. Mostly in your lower body.
February 4, 2026 at 4:14 AM
Week seven on pioglitazone:
Nothing now to report.
I can definitely see a body composition change, the fat under my skin has remained about the same, but the visceral fat which pioglitazone triggers the absorption of, is definitely reducing.
Week six on pioglitazone:
Energy remains high, mood remains good.

Liking everything so far.
Week five on Pioglitazone:
Starting to notice a change to my waistline, not sure if it's due to my increased level of activity —mermaiding season!— or to the metabolic signals pioglitazone should be creating.

The belief that whatever I eat is going to my hips is helping with my disordered eating.
April 18, 2025 at 2:56 PM
Week six on pioglitazone:
Energy remains high, mood remains good.

Liking everything so far.
Week five on Pioglitazone:
Starting to notice a change to my waistline, not sure if it's due to my increased level of activity —mermaiding season!— or to the metabolic signals pioglitazone should be creating.

The belief that whatever I eat is going to my hips is helping with my disordered eating.
Week Four on Pioglitazone:
Mood remains excellent, even after some really brutal days taking care of a friend.
I'm certain that it's also increasing my experienced energy levels.
I can just keep moving all day long, and I don't seem to get tired.
My craving for sweets is definitely gone. Strange.
April 12, 2025 at 12:02 PM
Their company’s patents are directed to dosing pioglitazone, a generic diabetes drug that has had a lot of buzz worthy research on slowing aging in lab mice and roundworms, etc.

It’s an old drug that in human medicine costs like $10 for a 90-pill bottle, so there’s some real rent-seeking here
August 12, 2025 at 2:07 PM
tits growing pros: you should consider going on a small doze of pioglitazone
May 4, 2026 at 7:15 PM
Yeah like his suppression curve for monotherapy? Spot on,
Studies into the indications of excercise and an elevated HGH level in breast growth? Also good.
Pioglitazone for feminizing fat distribution? Extremely based.

T for breast growth? Bonkers bullshit
March 31, 2025 at 7:30 PM
Sometimes I want to keep at intermittent fasting because it definitely helps my health. And sometimes looking at the state of everything, I just want to say fuck all, go on pioglitazone for my liver, and balloon up. I mean, I do fit the criteria for it.
September 21, 2025 at 5:58 AM
we are so fucking back dude
February 27, 2025 at 5:34 PM
Pioglitazone here we go.
February 21, 2025 at 12:57 AM
Pioglitazone enhances brain mitochondrial biogenesis and phase II detoxification capacity in neonatal rats with 6-OHDA-induced unilateral striatal lesions #MECFS #LongCovid

www.frontiersin.org/journals/neu...
Frontiers | Pioglitazone enhances brain mitochondrial biogenesis and phase II detoxification capacity in neonatal rats with 6-OHDA-induced unilateral striatal lesions
The psychostimulant methylphenidate (MPH) is the first-line pharmacological treatment for attentiondeficit/hyperactivity disorder (ADHD), but has numerous ad...
www.frontiersin.org
September 28, 2026 at 2:30 PM
I'm back and on a new routine, this is me one week inconsistently on pioglitazone at 236.4lbs with no dietary changes #feedee #feedeeism #feedism #feederism #gainer #gainerism #gainers
October 5, 2026 at 6:04 PM
I'm on oral meds, pioglitazone, glipizide, and metformin. I specifically steered my doctor towards putting me on meds that cause weight gain. Pioglitazone causes your body to produce new fat cells. Glipizide causes your pancreas to release insulin.
December 28, 2025 at 4:48 PM
I credit my massive fat pad to pioglitazone. I will caution that I did have an extremely minor incident of bladder cancer. It was caught so early and accidentally that treating it was easy. I'm still on it, but I do get bladder scopes annually just to be sure it doesn't come back.
February 4, 2026 at 4:27 AM
New research finds "local insulin signaling dysfunction plays a substantial role in GBA-#Parkinsons pathogenesis, exacerbating dopaminergic neuron death"; The investigators suggest anti-diabetic drug Pioglitazone rescues the cell death
movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...
November 24, 2024 at 12:34 AM
We're so on the same page! I'm on pioglitazone also!
January 6, 2026 at 7:18 PM
Astaxanthin, meclizine, mitoglitazone, pioglitazone, alpha-ketoglutarate, mifepristone, methotrexate, and atorvastatin-telmisartan do not increase lifespan in UM-HET3 mice
link.springer.com/article/10.1...
Astaxanthin, meclizine, mitoglitazone, pioglitazone, alpha-ketoglutarate, mifepristone, methotrexate, and atorvastatin-telmisartan do not increase lifespan in UM-HET3 mice - GeroScience
The Interventions Testing Program (ITP) evaluated eleven compounds in genetically heterogeneous UM-HET3 mice to assess their potential to extend lifespan. These interventions included both novel agent...
link.springer.com
March 22, 2026 at 5:48 PM
Key takeaways:
Patients with metformin-uncontrolled type 2 diabetes taking insulin and pioglitazone had greater risk for ischemic heart disease.
Older patients and men had greater risk for ischemic heart disease.
www.healio.com/news/endocri...
Pioglitazone added to insulin increases ischemic heart disease risk in type 2 diabetes
Patients with type 2 diabetes uncontrolled by metformin who received pioglitazone and insulin demonstrated increased risk for ischemic heart disease, according to findings published in the Journal of ...
www.healio.com
December 10, 2024 at 4:27 AM
pioglitazone is going to haunt my brain every month it seems
November 28, 2025 at 4:42 PM