🧪 AI-designed antibiotics
Scientists have used AI to design entirely new drugs to treat drug-resistant gonorrhoea and staph infections in mice.
🔗 www.cell.com/cell/abstrac...
#SciComm 🧪 #GenAI #AI #AMR
Scientists have used AI to design entirely new drugs to treat drug-resistant gonorrhoea and staph infections in mice.
🔗 www.cell.com/cell/abstrac...
#SciComm 🧪 #GenAI #AI #AMR
A generative deep learning approach to de novo antibiotic design
A generative AI platform is developed for de novo antibiotic design, yielding lead
compounds with selective antibacterial activity, distinct mechanisms of action, and
in vivo efficacy against multidru...
www.cell.com
September 21, 2025 at 1:10 AM
Neisseria meningitidis Conjunctivitis in Military Trainees — Texas: 41 cases of N. meningitidis conjunctivitis caused by an unencapsulated (nongroupable) strain www.cdc.gov/mmwr/volumes...?
Outbreak of Neisseria meningitidis Conjunctivitis ...
This report describes 41 cases of Neisseria meningitidis conjunctivitis among military trainees living in a communal setting in Texas.
www.cdc.gov
September 8, 2025 at 3:48 PM
As #AI becomes increasingly more involved in clinical decision-making, it is important to understand whose values are being represented.
In our next event, experts will discuss the complex web of priorities behind AI models in health care.
Sign up: nejm.ai/41ZDYDl
In our next event, experts will discuss the complex web of priorities behind AI models in health care.
Sign up: nejm.ai/41ZDYDl
September 8, 2025 at 6:31 PM
#JustPublished!
Drug-resistant fungus #CandidozymaAuris is spreading rapidly in European hospitals. #ECDC calls for urgent action.
📈 Cases are rising, outbreaks are larger, and several countries now report local transmission.
Press release: bit.ly/46uR1iK
#CandidaAuris #HAI #IDsky #EpiSky #AMR
Drug-resistant fungus #CandidozymaAuris is spreading rapidly in European hospitals. #ECDC calls for urgent action.
📈 Cases are rising, outbreaks are larger, and several countries now report local transmission.
Press release: bit.ly/46uR1iK
#CandidaAuris #HAI #IDsky #EpiSky #AMR
Drug-resistant fungus Candidozyma auris confirmed to spread rapidly in European hospitals: ECDC calls for urgent action
The latest survey from ECDC, the fourth of its kind, confirms that Candidozyma auris (formerly Candida auris) continues to spread quickly across European hospitals.
bit.ly
September 15, 2025 at 3:09 PM
Very interesting read on Long Covid symptoms among adolescents and when the symptoms resolved. #PITT_IDFall25
Prevalence of symptoms associated with Long COVID among adolescents in the United States, Summer 2022
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Prevalence of symptoms associated with Long COVID among adolescents in the United States, Summer 2022
Limited information is known about Long COVID among adolescents. This study will compare the risks associated with symptoms among adolescents who tested positive, were tested but never tested positive, and who were never tested for SARS-CoV-2 infection.
bit.ly
September 8, 2025 at 8:47 PM
Very interesting read on Long Covid symptoms among adolescents and when the symptoms resolved. #PITT_IDFall25
Very interesting article stating that influenza activity is increasing in Europe, RSV activity remains low, and SARSCoV2 activity is stable or decreasing. #PITT_IDFall25
#RespiratoryVirus situation update:
#Influenza activity is increasing in the EU/EEA, earlier than in recent seasons, while #RSV activity remains low.
#SARSCoV2 activity is stable or decreasing.
Read more here: erviss.org
#Flu #COVID19 #IDsky #EpiSky
#Influenza activity is increasing in the EU/EEA, earlier than in recent seasons, while #RSV activity remains low.
#SARSCoV2 activity is stable or decreasing.
Read more here: erviss.org
#Flu #COVID19 #IDsky #EpiSky
November 15, 2025 at 4:13 PM
Very interesting article stating that influenza activity is increasing in Europe, RSV activity remains low, and SARSCoV2 activity is stable or decreasing. #PITT_IDFall25
This is great news and safe for all. We should be promoting the consumption of pasteurized milk! #PITT_IDFall25
Pasteurization completely inactivates the H5N1 bird flu virus in milk.
www.sciencenews.org/article/past...
www.sciencenews.org/article/past...
Pasteurization destroys H5N1 bird flu in milk
Tests show pasteurized dairy with H5N1 remnants did not cause illness in mice, supporting safety of milk during outbreaks.
www.sciencenews.org
September 29, 2025 at 4:01 PM
This is great news and safe for all. We should be promoting the consumption of pasteurized milk! #PITT_IDFall25
Absence of Macrolide-resistant mutations in Bordetella pertussis in Antananarivo (Madagascar) and Cambodia during the last pertussis cycle before the COVID Pandemic
✅ Just Accepted
#IDSky
🔗 https://bit.ly/46yDDJl
✅ Just Accepted
#IDSky
🔗 https://bit.ly/46yDDJl
September 26, 2025 at 9:31 PM
Linezolid (n=43) vs Clinda + Vanc (n=199) for NSTI
No difference in # of surgical debridements between groups nor AKI, ICU LOS, antibiotic duration
No reporting on mortality or CDiff?
Always happy to see more on this topic!
#IDSky #TeamLinezolidNow 💰
www.liebertpub.com/doi/abs/10.1...
No difference in # of surgical debridements between groups nor AKI, ICU LOS, antibiotic duration
No reporting on mortality or CDiff?
Always happy to see more on this topic!
#IDSky #TeamLinezolidNow 💰
www.liebertpub.com/doi/abs/10.1...
Assessment of Therapeutic Approaches: Necrotizing Soft Tissue Infections and the Choice Between Vancomycin + Clindamycin and Linezolid | Surgical Infections
Background: Necrotizing skin and soft tissue infections (NSTIs) are life threatening, requiring antibiotic agents and surgical intervention. Clindamycin or linezolid is recommended as an adjunct thera...
www.liebertpub.com
September 12, 2025 at 1:35 PM
Linezolid (n=43) vs Clinda + Vanc (n=199) for NSTI
No difference in # of surgical debridements between groups nor AKI, ICU LOS, antibiotic duration
No reporting on mortality or CDiff?
Always happy to see more on this topic!
#IDSky #TeamLinezolidNow 💰
www.liebertpub.com/doi/abs/10.1...
No difference in # of surgical debridements between groups nor AKI, ICU LOS, antibiotic duration
No reporting on mortality or CDiff?
Always happy to see more on this topic!
#IDSky #TeamLinezolidNow 💰
www.liebertpub.com/doi/abs/10.1...
Assessment of Therapeutic Approaches: Necrotizing Soft Tissue Infections and the Choice Between Vancomycin + Clindamycin and Linezolid | Surgical Infections
Background: Necrotizing skin and soft tissue infections (NSTIs) are life threatening, requiring antibiotic agents and surgical intervention. Clindamycin or linezolid is recommended as an adjunct thera...
www.liebertpub.com
September 11, 2025 at 5:34 PM
Safety, Tolerability, and Immunogenicity of Revaccination with mRNA-1345, an mRNA Vaccine Against RSV, Administered 12 Months Following a Primary Dose in Adults Aged =50 Years
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4pFYaV2
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4pFYaV2
September 27, 2025 at 11:11 PM
Cholera surges in Chad as vaccine campaign launches in Sudan
The vaccine campaign targeting 1.86 million people in Darfur region faces daunting access and transportation challenges amid ongoing conflict.
www.cidrap.umn.edu/c...
UN/JC McIlwaine/Flickr cc
The vaccine campaign targeting 1.86 million people in Darfur region faces daunting access and transportation challenges amid ongoing conflict.
www.cidrap.umn.edu/c...
UN/JC McIlwaine/Flickr cc
September 27, 2025 at 11:10 PM
Study on Leishmania tropica in Morocco found 7 nearly identical genotype groups & mixed ancestry, indicating micro-focal human transmission. Direct genome sequencing proved effective. 🦠🔬##idsky
Direct genome sequencing of Leishmania tropica in tissues of Moroccan patients with cutaneous leishmaniasis reveals micro-focal transmission underlain by (pseudo-)clonal and sexual reproduction modes
AbstractLeishmania tropica is causing cutaneous leishmaniasis (CL) from North Africa to India and in Ethiopia and is reported to be transmitted from humans to humans through sand fly bites. While this species is characterized by a high genomic diversity all over the area of endemicity, there is very little information on diversity at micro-epidemiological scale. Here, we zoomed on an epidemic Moroccan focus of CL and studied transmission patterns by comparative genomics of parasites in human patients. We used a culture-independent method of genome sequencing, applied directly on dermal scrapings. We identified 7 groups of nearly identical genotypes, as well as parasites with mixed ancestry. Our results reveal a micro-focal transmission among humans, underlain by (pseudo) clonal and sexual reproductive modes. This study demonstrates the power of direct genome sequencing for evolutionary genetics at a micro-epidemiological scale.
academic.oup.com
September 22, 2025 at 2:04 PM
Very interesting article stating that hospital-acquired COVID-19 is associated with increased length and cost of stay in health care settings in Australia. #PITT_ID25
Hospital-acquired COVID-19 is associated with increased length and cost of stay in an Australian health care setting - American Journal of Infection Control www.ajicjournal.org/article/S019...
September 8, 2025 at 8:49 PM
Enhancing the Care of Patients with Bone and Joint Infections through Educational Interventions
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Enhancing the Care of Patients with Bone and Joint Infections through Educational Interventions
bit.ly
September 13, 2025 at 9:47 PM
🚨 Ebola Outbreak in Kasai Province, DRC. 28 suspected cases and 15 deaths, including 4 health-care workers, have been reported. Africa CDC & the WHO are mobilizing rapid response teams, vaccines, & supplies to contain the outbreak. #IDsky #MEDsky
More details: www.contagionlive.com/view/ebola-o...
More details: www.contagionlive.com/view/ebola-o...
September 8, 2025 at 5:18 PM
Outcomes of Military Blood Donors with Reactive Trypanosoma cruzi Antibody Screening
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Outcomes of Military Blood Donors with Reactive Trypanosoma cruzi Antibody Screening
Civilian blood donors in the United States are universally screened once for Trypanosoma cruzi antibodies to prevent transfusion-transmitted Chagas disease, while military donors are screened with every donation.
bit.ly
September 9, 2025 at 5:46 PM
FLAIR phase 3 trial: Long-term therapy for chronic lymphocytic leukemia can lead to resistance and toxic effects. Research findings on measurable residual disease–guided treatment with ibrutinib–venetoclax are summarized in a new Quick Take video. nej.md/46RcQt4
#MedSky #Hematology
#MedSky #Hematology
September 29, 2025 at 2:21 AM
Streptococcus anginosus Group of Bacteria are an Underappreciated Cause of Pneumonia.
✅ Just Accepted
#IDSky
🔗 https://bit.ly/48tWCHo
✅ Just Accepted
#IDSky
🔗 https://bit.ly/48tWCHo
September 21, 2025 at 6:38 PM
Case Record of the Massachusetts General Hospital: A 93-year-old woman was evaluated by her primary care physician because of dyspnea. She had a history of aortic stenosis and atrial fibrillation and flutter. A diagnosis was made. Read the full case details: nej.md/4nnSjSb
#MedSky
#MedSky
September 14, 2025 at 11:51 PM
Richer countries don’t just avoid infectious disease — they also have lower rates of chronic disease deaths.
September 29, 2025 at 1:02 PM
PITT_IDFall25
Love this abstract from ELSO 2025:
Stopping daily surveillance blood cultures on pediatric ECMO pts led to significant decrease in antibiotic use.
Such a great example of a group using local data to update their local practice.
#IDSky
journals.lww.com/asaiojournal...
Stopping daily surveillance blood cultures on pediatric ECMO pts led to significant decrease in antibiotic use.
Such a great example of a group using local data to update their local practice.
#IDSky
journals.lww.com/asaiojournal...
journals.lww.com
September 29, 2025 at 12:19 PM
PITT_IDFall25
HIV resistance to dolutegravir varies with co-administered agents
✅ Just Accepted
#IDSky
https://bit.ly/4n0HvtF
✅ Just Accepted
#IDSky
https://bit.ly/4n0HvtF
HIV resistance to dolutegravir varies with co-administered agents
We hypothesized that HIV-dolutegravir-resistance is more frequent when co-administered with nucleos(t)ides with shorter intracellular half-lives.
bit.ly
September 15, 2025 at 3:09 PM
September 8, 2025 at 3:48 PM
#JustPublished!
Drug-resistant fungus #CandidozymaAuris is spreading rapidly in European hospitals. #ECDC calls for urgent action.
📈 Cases are rising, outbreaks are larger, and several countries now report local transmission.
Press release: bit.ly/46uR1iK
#CandidaAuris #HAI #IDsky #EpiSky #AMR
Drug-resistant fungus #CandidozymaAuris is spreading rapidly in European hospitals. #ECDC calls for urgent action.
📈 Cases are rising, outbreaks are larger, and several countries now report local transmission.
Press release: bit.ly/46uR1iK
#CandidaAuris #HAI #IDsky #EpiSky #AMR
Drug-resistant fungus Candidozyma auris confirmed to spread rapidly in European hospitals: ECDC calls for urgent action
The latest survey from ECDC, the fourth of its kind, confirms that Candidozyma auris (formerly Candida auris) continues to spread quickly across European hospitals.
bit.ly
September 11, 2025 at 6:29 PM