www.biorxiv.org/content/10.6...
Layered helical order reveals assembly states in podosome actin networks
Layered helical order reveals assembly states in podosome actin networks
July 28, 2026 at 11:59 AM
www.biorxiv.org/content/10.6...
Layered helical order reveals assembly states in podosome actin networks
Layered helical order reveals assembly states in podosome actin networks
Our paper on podosome regulation by myosins 1e/f is now online.
We introduce the concept of the podosome base, a region of plasma membrane-associated components 🔬
Cool collaboration with @renaudpoincloux.bsky.social and Krendel labs
www.sciencedirect.com/science/arti...
We introduce the concept of the podosome base, a region of plasma membrane-associated components 🔬
Cool collaboration with @renaudpoincloux.bsky.social and Krendel labs
www.sciencedirect.com/science/arti...
September 2, 2025 at 7:48 AM
Our paper on podosome regulation by myosins 1e/f is now online.
We introduce the concept of the podosome base, a region of plasma membrane-associated components 🔬
Cool collaboration with @renaudpoincloux.bsky.social and Krendel labs
www.sciencedirect.com/science/arti...
We introduce the concept of the podosome base, a region of plasma membrane-associated components 🔬
Cool collaboration with @renaudpoincloux.bsky.social and Krendel labs
www.sciencedirect.com/science/arti...
Our preprint on podosome regulation by unconventional myosins in now on BioRxiv. Great collaboration with the @renaudpoincloux.bsky.social and Krendel labs.
www.biorxiv.org/content/10.1...
We introduce the concept of the "podosome base", a region of plasma membrane-associated podosome components.
www.biorxiv.org/content/10.1...
We introduce the concept of the "podosome base", a region of plasma membrane-associated podosome components.
April 30, 2025 at 8:14 AM
Our preprint on podosome regulation by unconventional myosins in now on BioRxiv. Great collaboration with the @renaudpoincloux.bsky.social and Krendel labs.
www.biorxiv.org/content/10.1...
We introduce the concept of the "podosome base", a region of plasma membrane-associated podosome components.
www.biorxiv.org/content/10.1...
We introduce the concept of the "podosome base", a region of plasma membrane-associated podosome components.
A warm welcome to our new PhD student Emma Lautenbach, who will work on the intricacies of the podosome cap 🧢
November 17, 2025 at 12:23 PM
A warm welcome to our new PhD student Emma Lautenbach, who will work on the intricacies of the podosome cap 🧢
Infection-Induced Dynamin-2 Repurposing Drives Podosome Maturation and Mechanical Immunity https://www.biorxiv.org/content/10.64898/2026.07.01.735798v1
July 10, 2026 at 4:30 AM
Infection-Induced Dynamin-2 Repurposing Drives Podosome Maturation and Mechanical Immunity https://www.biorxiv.org/content/10.64898/2026.07.01.735798v1
XIRP1 is a podosome-associated ISG that targets cytosolic bacteria as part of the IFN-γ-induced defense program in humans @jimmunol.bsky.social
academic.oup.com/jimmunol/art... @yalemicropath.bsky.social
academic.oup.com/jimmunol/art... @yalemicropath.bsky.social
June 18, 2026 at 5:40 PM
XIRP1 is a podosome-associated ISG that targets cytosolic bacteria as part of the IFN-γ-induced defense program in humans @jimmunol.bsky.social
academic.oup.com/jimmunol/art... @yalemicropath.bsky.social
academic.oup.com/jimmunol/art... @yalemicropath.bsky.social
#Mechanobiology
Synergistic impacts of Pressure (120/60 vs 180/120 mmHg) & Matrix Stiffness (1 vs 130 kPa) on Smooth Muscle Cell cytoskeleton/Podosome/motility
Elevated pressure⬇️SMC cellular stiffness (3.8▶️2.2 kPa)
Cheng-han Yu & Thomas Iskratsch labs #SciAdv 2022
www.science.org/doi/full/10....
Synergistic impacts of Pressure (120/60 vs 180/120 mmHg) & Matrix Stiffness (1 vs 130 kPa) on Smooth Muscle Cell cytoskeleton/Podosome/motility
Elevated pressure⬇️SMC cellular stiffness (3.8▶️2.2 kPa)
Cheng-han Yu & Thomas Iskratsch labs #SciAdv 2022
www.science.org/doi/full/10....
April 3, 2026 at 6:53 PM
#Mechanobiology
Synergistic impacts of Pressure (120/60 vs 180/120 mmHg) & Matrix Stiffness (1 vs 130 kPa) on Smooth Muscle Cell cytoskeleton/Podosome/motility
Elevated pressure⬇️SMC cellular stiffness (3.8▶️2.2 kPa)
Cheng-han Yu & Thomas Iskratsch labs #SciAdv 2022
www.science.org/doi/full/10....
Synergistic impacts of Pressure (120/60 vs 180/120 mmHg) & Matrix Stiffness (1 vs 130 kPa) on Smooth Muscle Cell cytoskeleton/Podosome/motility
Elevated pressure⬇️SMC cellular stiffness (3.8▶️2.2 kPa)
Cheng-han Yu & Thomas Iskratsch labs #SciAdv 2022
www.science.org/doi/full/10....
It's a podosome https://twitter.com/neuroecology/status/1115965546632306689
December 30, 2024 at 5:12 PM
It's a podosome https://twitter.com/neuroecology/status/1115965546632306689
The authors included RRIDs in their None paper! Thanks for making your methods matter! #OpenScience #methodsmatter #reproducibility
Myosins 1e/f at the podosome base regulate podosome dynamics and promote macrophage migration
doi.org
September 7, 2025 at 7:00 AM
The authors included RRIDs in their None paper! Thanks for making your methods matter! #OpenScience #methodsmatter #reproducibility
Layered helical order reveals assembly states in podosome actin networks https://www.biorxiv.org/content/10.64898/2026.07.24.740591v1
July 27, 2026 at 2:31 PM
Layered helical order reveals assembly states in podosome actin networks https://www.biorxiv.org/content/10.64898/2026.07.24.740591v1
A preprint using: Anti-myo1e (RRID:AB_2909514) from #MarkMooseker-Yale was published.
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #reproducibility
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #reproducibility
Myo1e/f at the podosome base regulate podosome dynamics and promote macrophage migration
www.biorxiv.org
May 4, 2025 at 12:00 PM
A preprint using: Anti-myo1e (RRID:AB_2909514) from #MarkMooseker-Yale was published.
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #reproducibility
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #reproducibility
Segregating AND Combining the impacts of Pressure (Ca2+) vs #MatrixStiffness (RhoA-LIMK) on #SmoothMuscleCell phenotypic plasticity
Converging on #Cofilin #Podosome Mechanosensing
Nice Intro to SMC #Mechanobiology🤓
#ScienceAdvances 2022
www.science.org/doi/10.1126/...
Converging on #Cofilin #Podosome Mechanosensing
Nice Intro to SMC #Mechanobiology🤓
#ScienceAdvances 2022
www.science.org/doi/10.1126/...
December 27, 2023 at 8:04 PM
Segregating AND Combining the impacts of Pressure (Ca2+) vs #MatrixStiffness (RhoA-LIMK) on #SmoothMuscleCell phenotypic plasticity
Converging on #Cofilin #Podosome Mechanosensing
Nice Intro to SMC #Mechanobiology🤓
#ScienceAdvances 2022
www.science.org/doi/10.1126/...
Converging on #Cofilin #Podosome Mechanosensing
Nice Intro to SMC #Mechanobiology🤓
#ScienceAdvances 2022
www.science.org/doi/10.1126/...
A warm welcome to our new master student Mahmood Tarmom, who will work on podosome proteins of (yet) unknown function 🔬
July 4, 2025 at 1:15 PM
A warm welcome to our new master student Mahmood Tarmom, who will work on podosome proteins of (yet) unknown function 🔬
RRID:Addgene_26734 was used by the authors of the Cellular and Molecular Life Sciences paper "PI(3,4,5)P3-mediated Cdc42 activation regulates macrophage podosome assembly". RRIDs like this improve reproducibility in scientific research. #STMpublishing #RRID
doi.org
April 13, 2025 at 7:00 AM
RRID:Addgene_26734 was used by the authors of the Cellular and Molecular Life Sciences paper "PI(3,4,5)P3-mediated Cdc42 activation regulates macrophage podosome assembly". RRIDs like this improve reproducibility in scientific research. #STMpublishing #RRID
The study shows that the protrusions in immune cells that sense extracellular matrix increases oscillations and decreases their depth when matrix stiffness is increased establishing a theoretical framework for understanding a link between interfacial mechanics and podosome dynamics. buff.ly/PQVjEal
https://www.cell.com/biophysj/fulltext/S0006-3495(26)00420-0
www.cell.com
September 8, 2026 at 2:02 PM
The study shows that the protrusions in immune cells that sense extracellular matrix increases oscillations and decreases their depth when matrix stiffness is increased establishing a theoretical framework for understanding a link between interfacial mechanics and podosome dynamics. buff.ly/PQVjEal
Layered helical order reveals assembly states in podosome actin networks www.biorxiv.org/content/10.64898/2026.07.24.740591v1 #cryoem
July 28, 2026 at 10:27 AM
Layered helical order reveals assembly states in podosome actin networks www.biorxiv.org/content/10.64898/2026.07.24.740591v1 #cryoem
Layered helical order reveals assembly states in podosome actin networks https://www.biorxiv.org/content/10.64898/2026.07.24.740591v1
July 27, 2026 at 2:31 PM
Layered helical order reveals assembly states in podosome actin networks https://www.biorxiv.org/content/10.64898/2026.07.24.740591v1
Infection-Induced Dynamin-2 Repurposing Drives Podosome Maturation and Mechanical Immunity https://www.biorxiv.org/content/10.64898/2026.07.01.735798v1
July 10, 2026 at 4:30 AM
Infection-Induced Dynamin-2 Repurposing Drives Podosome Maturation and Mechanical Immunity https://www.biorxiv.org/content/10.64898/2026.07.01.735798v1
Congratulations to our lab member Bryan Barcelona to a super fancy defense on software-based analysis of cell and podosome parameters 👨🎓
August 26, 2025 at 7:07 AM
Congratulations to our lab member Bryan Barcelona to a super fancy defense on software-based analysis of cell and podosome parameters 👨🎓
Modular actin nano-architecture enables podosome protrusion and mechanosensing by Koen van den Dries & Leila Nahidiazar & Johan A. Slotman & Marjolein B. M. Meddens & Elvis Pandzic & Ben Joosten & Marleen Ansems & Joost Schouwstra & Anke Meijer & Raymond Steen & Mietske Wijers & Ja (2019)
IDEAS/RePEc link
to RePEc:nat:natcom:v:10:y:2019:i:1:d:10.1038_s41467-019-13123-3
ideas.repec.org
May 4, 2026 at 3:50 AM
Modular actin nano-architecture enables podosome protrusion and mechanosensing by Koen van den Dries & Leila Nahidiazar & Johan A. Slotman & Marjolein B. M. Meddens & Elvis Pandzic & Ben Joosten & Marleen Ansems & Joost Schouwstra & Anke Meijer & Raymond Steen & Mietske Wijers & Ja (2019)
Podosome organization driven by actomyosin patterns (with nice SIM and time-window STICS images) http://www.nature.com/articles/ncomms13127
December 27, 2024 at 5:28 PM
Podosome organization driven by actomyosin patterns (with nice SIM and time-window STICS images) http://www.nature.com/articles/ncomms13127
Myo1e/f at the podosome base regulate podosome dynamics and promote macrophage migration https://www.biorxiv.org/content/10.1101/2025.04.28.651090v1
April 29, 2025 at 4:31 PM
Myo1e/f at the podosome base regulate podosome dynamics and promote macrophage migration https://www.biorxiv.org/content/10.1101/2025.04.28.651090v1
Extracellular HDAC6 ZnF UBP domain enhances podosome-mediated neuronal migration https://www.biorxiv.org/content/10.1101/2024.12.04.626746v1
Extracellular HDAC6 ZnF UBP domain enhances podosome-mediated neuronal migration https://www.biorxiv.org/content/10.1101/2024.12.04.626746v1
The increasing prevalence of Alzheimers disease demands research into therapeutic strategies that go
www.biorxiv.org
December 5, 2024 at 1:30 PM
Extracellular HDAC6 ZnF UBP domain enhances podosome-mediated neuronal migration https://www.biorxiv.org/content/10.1101/2024.12.04.626746v1
Myo1e/f at the podosome base regulate podosome dynamics and promote macrophage migration https://www.biorxiv.org/content/10.1101/2025.04.28.651090v1
April 29, 2025 at 4:31 PM
Myo1e/f at the podosome base regulate podosome dynamics and promote macrophage migration https://www.biorxiv.org/content/10.1101/2025.04.28.651090v1