In my defense: psilocybin gummy. Also dumb.
October 30, 2026 at 12:17 AM
In my defense: psilocybin gummy. Also dumb.
I wonder if anyone’s tried listening to music on psilocybin? Might be something there
November 3, 2026 at 3:34 PM
I wonder if anyone’s tried listening to music on psilocybin? Might be something there
Psilocybin collection from IKEA
November 2, 2026 at 5:00 PM
Psilocybin collection from IKEA
(I'm reallllllllly curious about the value of the client who wanted to send us a kg or two of pure(!!!!) psilocybin)
November 2, 2026 at 8:27 PM
(I'm reallllllllly curious about the value of the client who wanted to send us a kg or two of pure(!!!!) psilocybin)
Every time I see one, I wonder if I've accidentally eaten some psilocybin
November 3, 2026 at 8:59 PM
Every time I see one, I wonder if I've accidentally eaten some psilocybin
Psilocybin and a cookie
November 3, 2026 at 11:51 PM
Psilocybin and a cookie
Long suspected, finally confirmed. Next six months are going to be huge for the field of psychedelic medicine.
Two different psilocybin filings and one MDMA already under FDA review while LSD not far behind in the new year.
Two different psilocybin filings and one MDMA already under FDA review while LSD not far behind in the new year.
Usona Files Psilocybin for Depression NDA as Race With Compass Tightens
Nonprofit psychedelic research organisation Usona Institute has completed its submission of a new drug application (NDA) to the U.S. Food and Drug Administration (FDA) concerning its psilocybin candid...
psychedelicalpha.com
November 3, 2026 at 1:21 AM
Long suspected, finally confirmed. Next six months are going to be huge for the field of psychedelic medicine.
Two different psilocybin filings and one MDMA already under FDA review while LSD not far behind in the new year.
Two different psilocybin filings and one MDMA already under FDA review while LSD not far behind in the new year.
Scientists Separated Psilocybin's Brain Benefits From Its Hallucinogenic Trip
www.sciencealert.com/scientists-s...
www.sciencealert.com/scientists-s...
Scientists Separated Psilocybin's Brain Benefits From Its Hallucinogenic Trip
Psilocybin, the psychedelic compound in 'magic mushrooms', is being looked at for treatments for depression and post-traumatic stress disorder (PTSD).
www.sciencealert.com
November 2, 2026 at 2:45 PM
Scientists Separated Psilocybin's Brain Benefits From Its Hallucinogenic Trip
www.sciencealert.com/scientists-s...
www.sciencealert.com/scientists-s...
Magic pathways: the genes and enzymes of psilocybin biosynthesis
#microbiology #psilocybin #fungi #MicroSky
@asm.org
journals.asm.org/doi/10.1128/...
#microbiology #psilocybin #fungi #MicroSky
@asm.org
journals.asm.org/doi/10.1128/...
Magic pathways: the genes and enzymes of psilocybin biosynthesis | Microbiology and Molecular Biology Reviews
SUMMARYSpecies of several mushroom genera, among them Psilocybe and Inocybe, biosynthesize psilocybin, the prodrug to the powerful psychotropic and perception-altering
analog, psilocin. While “magic” ...
journals.asm.org
November 2, 2026 at 8:20 AM
Magic pathways: the genes and enzymes of psilocybin biosynthesis
#microbiology #psilocybin #fungi #MicroSky
@asm.org
journals.asm.org/doi/10.1128/...
#microbiology #psilocybin #fungi #MicroSky
@asm.org
journals.asm.org/doi/10.1128/...
Can we normalize psilocybin?
October 28, 2026 at 1:50 PM
Can we normalize psilocybin?
Our collaborative paper looking at acute and persistent effects of one dose of psilocybin in a range of mouse behavioral assays is out: rdcu.be/iiHBMSyDARWa. We learned a ton doing this with @indigenerd.bsky.social, @theborislab.bsky.social, @mazenkheirbek.bsky.social + the Lammel and Malenka labs!
rdcu.be
November 3, 2026 at 5:54 PM
Our collaborative paper looking at acute and persistent effects of one dose of psilocybin in a range of mouse behavioral assays is out: rdcu.be/iiHBMSyDARWa. We learned a ton doing this with @indigenerd.bsky.social, @theborislab.bsky.social, @mazenkheirbek.bsky.social + the Lammel and Malenka labs!
Psilocybin kann Gehirnschaltkreise umbauen – auch ohne Halluzinationen https://wp.me/p36Ae-1jmO Der Wirkstoff der „Zauberpilze“ stärkt neue Nervenverbindungen, ohne dass die halluzinogene Wirkung dafür nötig ist. Das könnte neue Medikamente ermöglichen. #Psiöocybin #Medics
Psilocybin kann Gehirnschaltkreise umbauen – auch ohne Halluzinationen
Der Wirkstoff der „Zauberpilze“ stärkt neue Nervenverbindungen, ohne dass die halluzinogene Wirkung dafür nötig ist. Das könnte neue Medikamente ermöglichen. Marcel Kunzmann | TELEPOLIS Forscher konnten neue Erkenntnisse zur Wirkung psychoaktiver Pilze gewinnen(Bild: New Africa/Shutterstock.com) Der Wirkstoff Psilocybin aus bestimmten Pilzen verändert die Verbindungen zwischen Nervenzellen im Gehirn, und zwar über einen Mechanismus, der von der halluzinogenen Wirkung getrennt ist.
brightsblog.wordpress.com
November 1, 2026 at 10:36 AM
Psilocybin kann Gehirnschaltkreise umbauen – auch ohne Halluzinationen https://wp.me/p36Ae-1jmO Der Wirkstoff der „Zauberpilze“ stärkt neue Nervenverbindungen, ohne dass die halluzinogene Wirkung dafür nötig ist. Das könnte neue Medikamente ermöglichen. #Psiöocybin #Medics
Hi Folks. I’ll be speaking at CIIS in San Francisco on Nov. 19 about the past, present & future of #psilocybin 🍄
Join me as we explore their potential to reshape our understanding of consciousness, human evolution & our relationship w/ the natural world.
See you there: www.ciis.edu/events/eveni...
Join me as we explore their potential to reshape our understanding of consciousness, human evolution & our relationship w/ the natural world.
See you there: www.ciis.edu/events/eveni...
Paul Stamets on Reimagining the Future with Psilocybin Mushrooms | CIIS
Join mycologist Paul Stamets for a talk on the history, science, and future of psilocybin mushrooms and their potential to help humanity evolve.
www.ciis.edu
October 28, 2026 at 4:28 PM
Hi Folks. I’ll be speaking at CIIS in San Francisco on Nov. 19 about the past, present & future of #psilocybin 🍄
Join me as we explore their potential to reshape our understanding of consciousness, human evolution & our relationship w/ the natural world.
See you there: www.ciis.edu/events/eveni...
Join me as we explore their potential to reshape our understanding of consciousness, human evolution & our relationship w/ the natural world.
See you there: www.ciis.edu/events/eveni...
Psychedelic Alpha reports Usona has likely filed an NDA for psilocybin in major depression, intensifying competition with #$CMPS and other developers. #$DFTX, #$HELP, #$GHRS notreload.xyz/xy/usona-psi...
Usona Psilocybin NDA Filing Intensifies Competition
Usona’s potential FDA filing for psilocybin makes the competitive landscape more real for Compass, Definium, Helus Pharma and GH Research, analyst says.
notreload.xyz
November 2, 2026 at 8:37 PM
Psychedelic Alpha reports Usona has likely filed an NDA for psilocybin in major depression, intensifying competition with #$CMPS and other developers. #$DFTX, #$HELP, #$GHRS notreload.xyz/xy/usona-psi...
my take: old fashioned measures of spontaneous mouse behaviors and "plasticity" associated with those behaviors may have little to do with the therapeutic outcome of receiving psilocybin under clinical supervision
November 2, 2026 at 4:33 PM
my take: old fashioned measures of spontaneous mouse behaviors and "plasticity" associated with those behaviors may have little to do with the therapeutic outcome of receiving psilocybin under clinical supervision
Mexico's psilocybin retreats cluster in four regions. A side-by-side comparison of Playa del Carmen, Tulum, Valle de Bravo, the Nayarit coast and Oaxaca on price, access, style and who each suits.
Psilocybin Retreats in Mexico by Region: Playa del Carmen, Tulum, Valle de Bravo, Sayulita, Oaxaca
Compare Mexico's psilocybin retreat regions on price, airport access, style and safety: Playa del Carmen, Tulum, Valle de Bravo, Sayulita and the Mazatec highlands of Oaxaca.
lifesynergyretreat.com
November 3, 2026 at 2:00 PM
Mexico's psilocybin retreats cluster in four regions. A side-by-side comparison of Playa del Carmen, Tulum, Valle de Bravo, the Nayarit coast and Oaxaca on price, access, style and who each suits.
What resonates most with me about this fascinating new study in JAMA Psychiatry is the possibility that psilocybin may do more than improve mood in Parkinson’s disease; it may also influence biological pathways involved in neurodegeneration.
cutt.ly/DyUWvMEF
cutt.ly/DyUWvMEF
November 2, 2026 at 12:32 PM
What resonates most with me about this fascinating new study in JAMA Psychiatry is the possibility that psilocybin may do more than improve mood in Parkinson’s disease; it may also influence biological pathways involved in neurodegeneration.
cutt.ly/DyUWvMEF
cutt.ly/DyUWvMEF
33 percent laxative, 33 percent weed, 33 percent psilocybin? Eat a whole bar of it
November 1, 2026 at 11:19 PM
33 percent laxative, 33 percent weed, 33 percent psilocybin? Eat a whole bar of it
Out now a huge multi-institute effort featuring our own Odilia Lu in collaboration, with labs at Berkeley, Stanford and UCSF on the acute and persistent effects of psilocybin in mice. Check it out, and congrats to everyone involved 🎉
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A multi-institutional investigation of psilocybin’s effects on mouse behavior - Nature Neuroscience
In a study across five independent labs, 2 mg kg−1 psilocybin in mice acutely increased avoidance-related behaviors in a robust, reproducible manner and acutely reduced fear expression, but previously...
www.nature.com
November 2, 2026 at 3:48 PM
Out now a huge multi-institute effort featuring our own Odilia Lu in collaboration, with labs at Berkeley, Stanford and UCSF on the acute and persistent effects of psilocybin in mice. Check it out, and congrats to everyone involved 🎉
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A lot of them might actually benefit from a good psilocybin ride
October 31, 2026 at 5:26 PM
A lot of them might actually benefit from a good psilocybin ride