Happening now, @pacbio.bsky.social PureTarget poster presented by @jocelyne8.bsky.social at #ACMG poster #340. Learn about PureTarget for scalable #HiFi sequencing of native DNA #repeatexpansions #longreads
March 21, 2025 at 5:31 PM
Happening now, @pacbio.bsky.social PureTarget poster presented by @jocelyne8.bsky.social at #ACMG poster #340. Learn about PureTarget for scalable #HiFi sequencing of native DNA #repeatexpansions #longreads
Repeat expansions and other complex genomic regions continue to challenge traditional sequencing workflows.
🎥 Hear how Dr. Maximilian Thelen is using PureTarget™ HiFi sequencing for repeat expansion analysis and custom panel development.
Watch the recording: bit.ly/3S1axP5
#PureTarget
🎥 Hear how Dr. Maximilian Thelen is using PureTarget™ HiFi sequencing for repeat expansion analysis and custom panel development.
Watch the recording: bit.ly/3S1axP5
#PureTarget
June 9, 2026 at 4:05 PM
Repeat expansions and other complex genomic regions continue to challenge traditional sequencing workflows.
🎥 Hear how Dr. Maximilian Thelen is using PureTarget™ HiFi sequencing for repeat expansion analysis and custom panel development.
Watch the recording: bit.ly/3S1axP5
#PureTarget
🎥 Hear how Dr. Maximilian Thelen is using PureTarget™ HiFi sequencing for repeat expansion analysis and custom panel development.
Watch the recording: bit.ly/3S1axP5
#PureTarget
nf-core/pacvar: Longread PacBio sequencing processing for WGS and PureTarget Nextflow pipeline https://github.com/nf-core/pacvar https://nf-co.re/pacvar 🧬🖥️🧪
February 5, 2025 at 4:30 PM
nf-core/pacvar: Longread PacBio sequencing processing for WGS and PureTarget Nextflow pipeline https://github.com/nf-core/pacvar https://nf-co.re/pacvar 🧬🖥️🧪
ESHG has been really fun so far. Check out the PacBio satellite symposium tomorrow where I’ll be talking about what’s coming next with PureTarget. 14:15 in Amber 5-6. We’re about more than just the best party.
Join @sarahdoom.bsky.social for a preview of our must-see #ESHG2025 activities: expert talks, live #HiFiSequencing demos, tech showcases, and more. Come see what it’s all about! #Genomics
May 24, 2025 at 5:29 PM
ESHG has been really fun so far. Check out the PacBio satellite symposium tomorrow where I’ll be talking about what’s coming next with PureTarget. 14:15 in Amber 5-6. We’re about more than just the best party.
PureTarget from #PacBio delivers scalable, accurate repeat expansion analysis with full sequence resolution. See how #HiFiSequencing enables a single assay to streamline complex testing across over a dozen genes.
Watch now: bit.ly/4jYhzMO
#PrecisionWithHiFi
Watch now: bit.ly/4jYhzMO
#PrecisionWithHiFi
June 18, 2025 at 5:57 PM
PureTarget from #PacBio delivers scalable, accurate repeat expansion analysis with full sequence resolution. See how #HiFiSequencing enables a single assay to streamline complex testing across over a dozen genes.
Watch now: bit.ly/4jYhzMO
#PrecisionWithHiFi
Watch now: bit.ly/4jYhzMO
#PrecisionWithHiFi
Great poster presentation #ESHG2025 done by @sarahdoom.bsky.social on @pacbio.bsky.social PureTarget application 😃
May 25, 2025 at 8:50 AM
Great poster presentation #ESHG2025 done by @sarahdoom.bsky.social on @pacbio.bsky.social PureTarget application 😃
Quest Diagnostics launched a new test for ataxia using long-read sequencing based on the PacBio #PureTarget method. It can uncover hidden genetic causes of disease, including repeat expansions often missed by other tools.
Details here: bit.ly/4fcu4DV
#PacBio
Details here: bit.ly/4fcu4DV
#PacBio
Athena Diagnostics Improves Ataxia Movement Disorder Testing with Novel Long-Read Gene Sequencing
New test utilizes technology based on PacBio's PureTarget sequencing method to uncover genetic causes of disease BOSTON, July 29, 2025 /PRNewswire/ -- Athena Diagnostics, the specialty neurology...
bit.ly
July 29, 2025 at 3:25 PM
Quest Diagnostics launched a new test for ataxia using long-read sequencing based on the PacBio #PureTarget method. It can uncover hidden genetic causes of disease, including repeat expansions often missed by other tools.
Details here: bit.ly/4fcu4DV
#PacBio
Details here: bit.ly/4fcu4DV
#PacBio
News from #ACMGMtg25! PacBio PureTarget and #HiFisequencing technology are being used as part of a new streamlined ataxia confirmatory offering at Athena, a business of Quest Diagnostics. Visit #PacBio booth #816 and check out our PureTarget poster #340 to learn more. The Quest/Athena booth is #316.
March 20, 2025 at 8:31 PM
News from #ACMGMtg25! PacBio PureTarget and #HiFisequencing technology are being used as part of a new streamlined ataxia confirmatory offering at Athena, a business of Quest Diagnostics. Visit #PacBio booth #816 and check out our PureTarget poster #340 to learn more. The Quest/Athena booth is #316.
Join #PacBio at #ESHG2025 to explore scalable solutions for human disease research—from PureTarget panels to Kinnex RNA discoveries.
📍 Join us in Milan, 24–27 May.
📄 View the full agenda: bit.ly/3GG9wX7
The future of sequencing starts with HiFi...
📍 Join us in Milan, 24–27 May.
📄 View the full agenda: bit.ly/3GG9wX7
The future of sequencing starts with HiFi...
May 8, 2025 at 9:29 AM
Join #PacBio at #ESHG2025 to explore scalable solutions for human disease research—from PureTarget panels to Kinnex RNA discoveries.
📍 Join us in Milan, 24–27 May.
📄 View the full agenda: bit.ly/3GG9wX7
The future of sequencing starts with HiFi...
📍 Join us in Milan, 24–27 May.
📄 View the full agenda: bit.ly/3GG9wX7
The future of sequencing starts with HiFi...
PureTarget from #PacBio is a PCR-free Cas9 method that preserves methylation and reduces GC and size bias. Sequence expanded alleles, target complex regions, and multiplex up to 48 samples on Revio or Vega.
Watch now: bit.ly/4kWWoMg
#PrecisionWithHiFi
Watch now: bit.ly/4kWWoMg
#PrecisionWithHiFi
June 6, 2025 at 5:23 PM
PureTarget from #PacBio is a PCR-free Cas9 method that preserves methylation and reduces GC and size bias. Sequence expanded alleles, target complex regions, and multiplex up to 48 samples on Revio or Vega.
Watch now: bit.ly/4kWWoMg
#PrecisionWithHiFi
Watch now: bit.ly/4kWWoMg
#PrecisionWithHiFi
At ESHG, #PacBio unveiled the roadmap to expand PureTarget: updated repeat expansion and carrier panels, 96-plex automation, and a full analysis pipeline—built to streamline, scale, and simplify clinical research workflows.
Get the details: bit.ly/3ZHhENA
Get the details: bit.ly/3ZHhENA
PureTarget repeat expansion and carrier panels enable high-throughput clinical research solutions - PacBio
The updated PureTarget panel captures more “dark” genes, reduces costs, and is an easy workflow, ideal for labs looking to scale.
https://bit.ly/3ZHhENA"
May 29, 2025 at 10:39 PM
At ESHG, #PacBio unveiled the roadmap to expand PureTarget: updated repeat expansion and carrier panels, 96-plex automation, and a full analysis pipeline—built to streamline, scale, and simplify clinical research workflows.
Get the details: bit.ly/3ZHhENA
Get the details: bit.ly/3ZHhENA
@deborahmoine.bsky.social from #PacBio presents high-throughput HMW genomic DNA extraction from saliva for large-scale HiFi sequencing projects, using WGS or PureTarget workflows.
See it now during #ASHG25 at poster 4042!
See it now during #ASHG25 at poster 4042!
October 15, 2025 at 6:47 PM
@deborahmoine.bsky.social from #PacBio presents high-throughput HMW genomic DNA extraction from saliva for large-scale HiFi sequencing projects, using WGS or PureTarget workflows.
See it now during #ASHG25 at poster 4042!
See it now during #ASHG25 at poster 4042!
#PacBio enters the carrier screening market with new #PureTarget kits. A single test can now replace multiple specialized assays, streamlining workflows for labs and clinicians.
Learn more: bit.ly/46trXre
Learn more: bit.ly/46trXre
September 22, 2025 at 2:37 PM
#PacBio enters the carrier screening market with new #PureTarget kits. A single test can now replace multiple specialized assays, streamlining workflows for labs and clinicians.
Learn more: bit.ly/46trXre
Learn more: bit.ly/46trXre
As long read sequencing scales to large biobanks, it’s clear that DNA repeat expansions are more dynamic and individualized than once thought. Long read approaches like PureTarget helps bring challenging regions into focus, turning discovery into deeper biological insights.
📎 go.nature.com/49rjTc9
📎 go.nature.com/49rjTc9
January 8, 2026 at 8:25 PM
As long read sequencing scales to large biobanks, it’s clear that DNA repeat expansions are more dynamic and individualized than once thought. Long read approaches like PureTarget helps bring challenging regions into focus, turning discovery into deeper biological insights.
📎 go.nature.com/49rjTc9
📎 go.nature.com/49rjTc9
What can you learn from a clinical lab's PureTarget implementation?
Discover how the team at CHU Nîmes in France implemented #PacBio PureTarget and transitioned to routine clinical use in just ~3 months to expand repeat expansion testing.
Read the story: bit.ly/4fMGHWI
Discover how the team at CHU Nîmes in France implemented #PacBio PureTarget and transitioned to routine clinical use in just ~3 months to expand repeat expansion testing.
Read the story: bit.ly/4fMGHWI
August 7, 2026 at 3:43 PM
What can you learn from a clinical lab's PureTarget implementation?
Discover how the team at CHU Nîmes in France implemented #PacBio PureTarget and transitioned to routine clinical use in just ~3 months to expand repeat expansion testing.
Read the story: bit.ly/4fMGHWI
Discover how the team at CHU Nîmes in France implemented #PacBio PureTarget and transitioned to routine clinical use in just ~3 months to expand repeat expansion testing.
Read the story: bit.ly/4fMGHWI
This study uses the older No-Amp method from @pacbio.bsky.social . Check out the updated PureTarget approach which requires much less DNA (>=1ug) and is more robust. Available on Revio and Vega benchtop www.pacb.com/technology/p...
PureTarget - PacBio
PureTarget uses the CRISPR-Cas9 system to generate targeted native DNA libraries. This amplification-free approach retains epigenetic signals and has no PCR artifacts or errors.
www.pacb.com
December 30, 2024 at 8:10 PM
This study uses the older No-Amp method from @pacbio.bsky.social . Check out the updated PureTarget approach which requires much less DNA (>=1ug) and is more robust. Available on Revio and Vega benchtop www.pacb.com/technology/p...
Which targeted sequencing approach is right for you?
In this short video, Samantha walks through three key PacBio HiFi approaches: amplicon, hybrid capture, and PureTarget.
Watch to find the best fit to simplify your strategy: bit.ly/4ffnKMe
#PacBio #HiFiSequencing #Genomics
In this short video, Samantha walks through three key PacBio HiFi approaches: amplicon, hybrid capture, and PureTarget.
Watch to find the best fit to simplify your strategy: bit.ly/4ffnKMe
#PacBio #HiFiSequencing #Genomics
July 16, 2026 at 3:32 PM
Which targeted sequencing approach is right for you?
In this short video, Samantha walks through three key PacBio HiFi approaches: amplicon, hybrid capture, and PureTarget.
Watch to find the best fit to simplify your strategy: bit.ly/4ffnKMe
#PacBio #HiFiSequencing #Genomics
In this short video, Samantha walks through three key PacBio HiFi approaches: amplicon, hybrid capture, and PureTarget.
Watch to find the best fit to simplify your strategy: bit.ly/4ffnKMe
#PacBio #HiFiSequencing #Genomics
PacBio has a product called PureTarget for Cas9 based pull-down. The kit is specific to 20-ish repeat expansion genes in the human genome, but could be customized.
April 27, 2025 at 2:10 AM
PacBio has a product called PureTarget for Cas9 based pull-down. The kit is specific to 20-ish repeat expansion genes in the human genome, but could be customized.
It's @pacbio.bsky.social fairy tale Friday!
Once upon a time, you do lots of PCRs to screen different ataxia genes.
Now with PureTarget, you can do 20 genes at once, get repeat lengths, repeat sequences, and even methylation patterns!
Once upon a time, you do lots of PCRs to screen different ataxia genes.
Now with PureTarget, you can do 20 genes at once, get repeat lengths, repeat sequences, and even methylation patterns!
March 21, 2025 at 12:49 PM
It's @pacbio.bsky.social fairy tale Friday!
Once upon a time, you do lots of PCRs to screen different ataxia genes.
Now with PureTarget, you can do 20 genes at once, get repeat lengths, repeat sequences, and even methylation patterns!
Once upon a time, you do lots of PCRs to screen different ataxia genes.
Now with PureTarget, you can do 20 genes at once, get repeat lengths, repeat sequences, and even methylation patterns!
At @pacbio.bsky.social we improved upon our Cas9-based targeted library prep method which preserves methylation. It's easy to use, automation friendly, and very powerful for resolving the most complex genomic regions at scale. Learn more about PureTarget here www.pacb.com/technology/p...
PureTarget - PacBio
PureTarget uses the CRISPR-Cas9 system to generate targeted native DNA libraries. This amplification-free approach retains epigenetic signals and has no PCR artifacts or errors.
www.pacb.com
November 23, 2024 at 3:02 PM
At @pacbio.bsky.social we improved upon our Cas9-based targeted library prep method which preserves methylation. It's easy to use, automation friendly, and very powerful for resolving the most complex genomic regions at scale. Learn more about PureTarget here www.pacb.com/technology/p...
Excited to see our work featured! We evaluated PureTarget for verification of CRISPR-Cas9 genome editing outcomes, with great results. Read more in the publication spotlight by @pacbio.bsky.social and in our preprint: www.biorxiv.org/content/10.1...
www.pacb.com/blog/publica...
www.pacb.com/blog/publica...
Publication spotlight:Capturing the full picture of genome editing with custom PureTarget panels - PacBio
Genetic mosaicism can occur within genome editing. Accurately characterize every edit within a model with PureTarget.
www.pacb.com
October 31, 2025 at 1:07 PM
Excited to see our work featured! We evaluated PureTarget for verification of CRISPR-Cas9 genome editing outcomes, with great results. Read more in the publication spotlight by @pacbio.bsky.social and in our preprint: www.biorxiv.org/content/10.1...
www.pacb.com/blog/publica...
www.pacb.com/blog/publica...
Happy to present poster P23.040.D at #ESHG2026 today! 😃
Exploring how #PureTarget and #PacBio HiFi sequencing enable flexible targeting of challenging genomic regions, from repeat expansions to difficult inherited disease genes.
Exploring how #PureTarget and #PacBio HiFi sequencing enable flexible targeting of challenging genomic regions, from repeat expansions to difficult inherited disease genes.
June 14, 2026 at 9:25 AM
Happy to present poster P23.040.D at #ESHG2026 today! 😃
Exploring how #PureTarget and #PacBio HiFi sequencing enable flexible targeting of challenging genomic regions, from repeat expansions to difficult inherited disease genes.
Exploring how #PureTarget and #PacBio HiFi sequencing enable flexible targeting of challenging genomic regions, from repeat expansions to difficult inherited disease genes.
Streamlined sequencing deserves streamlined analysis.
The #PureTarget workflow brings complex variant types together into a single pipeline, combining PacBio tools to support comprehensive targeted data analysis.
📘 Download the Pre-Clinical Playbook: bit.ly/437tTEM
The #PureTarget workflow brings complex variant types together into a single pipeline, combining PacBio tools to support comprehensive targeted data analysis.
📘 Download the Pre-Clinical Playbook: bit.ly/437tTEM
June 18, 2026 at 4:50 PM
Streamlined sequencing deserves streamlined analysis.
The #PureTarget workflow brings complex variant types together into a single pipeline, combining PacBio tools to support comprehensive targeted data analysis.
📘 Download the Pre-Clinical Playbook: bit.ly/437tTEM
The #PureTarget workflow brings complex variant types together into a single pipeline, combining PacBio tools to support comprehensive targeted data analysis.
📘 Download the Pre-Clinical Playbook: bit.ly/437tTEM
Last call to register for our gene editing webinar!
Short reads and PCR bias can hide critical editing outcomes. Join us to see how amplification free #PacBio HiFi sequencing and PureTarget provide a complete view of #CRISPR edits.
Register here: bit.ly/4mbDW4i
Short reads and PCR bias can hide critical editing outcomes. Join us to see how amplification free #PacBio HiFi sequencing and PureTarget provide a complete view of #CRISPR edits.
Register here: bit.ly/4mbDW4i
April 26, 2026 at 7:04 PM
Last call to register for our gene editing webinar!
Short reads and PCR bias can hide critical editing outcomes. Join us to see how amplification free #PacBio HiFi sequencing and PureTarget provide a complete view of #CRISPR edits.
Register here: bit.ly/4mbDW4i
Short reads and PCR bias can hide critical editing outcomes. Join us to see how amplification free #PacBio HiFi sequencing and PureTarget provide a complete view of #CRISPR edits.
Register here: bit.ly/4mbDW4i
Focus your research on specific genes with #PacBio Targeted #HiFisequencing! Get cost-effective, scalable insights for tricky regions, accurate variants & phased haplotypes. Learn about PureTarget, HiFi Target Enrichment & PCR Amplicons.
Watch now: bit.ly/3Het9pD
#PrecisionWithHiFi
Watch now: bit.ly/3Het9pD
#PrecisionWithHiFi
May 29, 2025 at 4:16 PM
Focus your research on specific genes with #PacBio Targeted #HiFisequencing! Get cost-effective, scalable insights for tricky regions, accurate variants & phased haplotypes. Learn about PureTarget, HiFi Target Enrichment & PCR Amplicons.
Watch now: bit.ly/3Het9pD
#PrecisionWithHiFi
Watch now: bit.ly/3Het9pD
#PrecisionWithHiFi