basically impossible because excess pyridoxine will be lost in urine)
Turns out: pyridoxine competes with the active form of the coenzyme (PLP), so if there is a ton of it, the enzymes that depend on PLP won't work.
Meaning you get a deficiency-like syndrome from overdose.
Biology is silly.
Turns out: pyridoxine competes with the active form of the coenzyme (PLP), so if there is a ton of it, the enzymes that depend on PLP won't work.
Meaning you get a deficiency-like syndrome from overdose.
Biology is silly.
January 21, 2025 at 6:45 AM
basically impossible because excess pyridoxine will be lost in urine)
Turns out: pyridoxine competes with the active form of the coenzyme (PLP), so if there is a ton of it, the enzymes that depend on PLP won't work.
Meaning you get a deficiency-like syndrome from overdose.
Biology is silly.
Turns out: pyridoxine competes with the active form of the coenzyme (PLP), so if there is a ton of it, the enzymes that depend on PLP won't work.
Meaning you get a deficiency-like syndrome from overdose.
Biology is silly.
Excessive long-term use if vitamin B6, pyridoxine, can cause nerve damage (peripheral neuropathy).
June 4, 2026 at 4:48 PM
Excessive long-term use if vitamin B6, pyridoxine, can cause nerve damage (peripheral neuropathy).
Have you ever wanted to experience incredibly vivid and wild dreams at night? Try taking 5-HTP, pyridoxine (by itself, not in a B-vitamin complex), and magnesium L-threonate together before bed. It's an absolute trip in my experience.
February 3, 2026 at 8:23 PM
Have you ever wanted to experience incredibly vivid and wild dreams at night? Try taking 5-HTP, pyridoxine (by itself, not in a B-vitamin complex), and magnesium L-threonate together before bed. It's an absolute trip in my experience.
Potatoes have a Nutrivore Score of 272, which makes them a medium nutrient-dense food! They are particularly rich in vitamin C, polyphenols, vitamin B6 (pyridoxine), copper, potassium, fiber, manganese, vitamin B1 (thiamin), and vitamin B3 (niacin). #nutrivore
May 7, 2025 at 9:51 PM
Potatoes have a Nutrivore Score of 272, which makes them a medium nutrient-dense food! They are particularly rich in vitamin C, polyphenols, vitamin B6 (pyridoxine), copper, potassium, fiber, manganese, vitamin B1 (thiamin), and vitamin B3 (niacin). #nutrivore
A bit of info on B6:
It is this ⬇️ inactive, pyridoxine, form of B6 that can cause neuropathy.
The active, pyridoxal-5-phosphate (P5P) form doesn’t seem to be toxic.
Inactive pyridoxine blocks B6 metabolism when high in blood, mimicking B6 deficiency.
www.sciencedirect.com/science/arti...
It is this ⬇️ inactive, pyridoxine, form of B6 that can cause neuropathy.
The active, pyridoxal-5-phosphate (P5P) form doesn’t seem to be toxic.
Inactive pyridoxine blocks B6 metabolism when high in blood, mimicking B6 deficiency.
www.sciencedirect.com/science/arti...
January 14, 2025 at 12:47 PM
A bit of info on B6:
It is this ⬇️ inactive, pyridoxine, form of B6 that can cause neuropathy.
The active, pyridoxal-5-phosphate (P5P) form doesn’t seem to be toxic.
Inactive pyridoxine blocks B6 metabolism when high in blood, mimicking B6 deficiency.
www.sciencedirect.com/science/arti...
It is this ⬇️ inactive, pyridoxine, form of B6 that can cause neuropathy.
The active, pyridoxal-5-phosphate (P5P) form doesn’t seem to be toxic.
Inactive pyridoxine blocks B6 metabolism when high in blood, mimicking B6 deficiency.
www.sciencedirect.com/science/arti...
April 4, 2025 at 3:36 PM
Nutrients that stimulate muscle regeneration during muscle recovery and aging!
Sara Ancel, Joris Michaud, and colleagues show nicotinamide and pyridoxine enhance muscle regeneration in aged mice: https://www.jci.org/articles/view/163648
Sara Ancel, Joris Michaud, and colleagues show nicotinamide and pyridoxine enhance muscle regeneration in aged mice: https://www.jci.org/articles/view/163648
December 17, 2024 at 6:50 PM
Nutrients that stimulate muscle regeneration during muscle recovery and aging!
Sara Ancel, Joris Michaud, and colleagues show nicotinamide and pyridoxine enhance muscle regeneration in aged mice: https://www.jci.org/articles/view/163648
Sara Ancel, Joris Michaud, and colleagues show nicotinamide and pyridoxine enhance muscle regeneration in aged mice: https://www.jci.org/articles/view/163648
We are living in the fucking dumbest timeline ever!!!
It must be the same people screaming, “Keep these fucking additives (thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, biotin, folate/folic acid, and cobalamin) out of my food!!”
It must be the same people screaming, “Keep these fucking additives (thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, biotin, folate/folic acid, and cobalamin) out of my food!!”
Babies Are Bleeding to Death as Parents Reject a Vitamin Shot Given at Birth
A lifesaving injection given at birth to prevent severe bleeding has become collateral damage of the anti-vaccine movement.
www.propublica.org
May 6, 2026 at 10:07 PM
We are living in the fucking dumbest timeline ever!!!
It must be the same people screaming, “Keep these fucking additives (thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, biotin, folate/folic acid, and cobalamin) out of my food!!”
It must be the same people screaming, “Keep these fucking additives (thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, biotin, folate/folic acid, and cobalamin) out of my food!!”
So there was a news report some time ago about how someone was taking supplemental pyridoxine (vitamin B6) and managed to overdose on it and develop a sensory neuropathy, which confused me because:
- this is what happens when you have a deficiency of B6
- it's water-soluble (toxicity should be...
- this is what happens when you have a deficiency of B6
- it's water-soluble (toxicity should be...
January 21, 2025 at 6:45 AM
So there was a news report some time ago about how someone was taking supplemental pyridoxine (vitamin B6) and managed to overdose on it and develop a sensory neuropathy, which confused me because:
- this is what happens when you have a deficiency of B6
- it's water-soluble (toxicity should be...
- this is what happens when you have a deficiency of B6
- it's water-soluble (toxicity should be...
Specialised formula access expands for pyridoxine-dependent epilepsy.
https://www.mattheneus.com/editorial/pbac-ga1-anamix-pyridoxine-dependent-epilepsy-restricted-benefit-2026-07
#HTA #EvidenceSynthesis #HealthEconomics
https://www.mattheneus.com/editorial/pbac-ga1-anamix-pyridoxine-dependent-epilepsy-restricted-benefit-2026-07
#HTA #EvidenceSynthesis #HealthEconomics
October 4, 2026 at 11:03 AM
Specialised formula access expands for pyridoxine-dependent epilepsy.
https://www.mattheneus.com/editorial/pbac-ga1-anamix-pyridoxine-dependent-epilepsy-restricted-benefit-2026-07
#HTA #EvidenceSynthesis #HealthEconomics
https://www.mattheneus.com/editorial/pbac-ga1-anamix-pyridoxine-dependent-epilepsy-restricted-benefit-2026-07
#HTA #EvidenceSynthesis #HealthEconomics
As the son of 2 chemists, you should know what chemicals niacinamide and pyridoxine are.
December 20, 2024 at 3:11 PM
As the son of 2 chemists, you should know what chemicals niacinamide and pyridoxine are.
💪new 1st author publication @grithhojfeldt.bsky.social and Joris Michaud from fantastic #CollaborativeScience team effort bewteen @ismcopenhagen.bsky.social and Nestle @feigelab.bsky.social on the role of NAM/PN in human muscle regeneration🙌🏃🙌
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Rec...
In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN sup....
advanced.onlinelibrary.wiley.com
March 25, 2026 at 8:34 AM
💪new 1st author publication @grithhojfeldt.bsky.social and Joris Michaud from fantastic #CollaborativeScience team effort bewteen @ismcopenhagen.bsky.social and Nestle @feigelab.bsky.social on the role of NAM/PN in human muscle regeneration🙌🏃🙌
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Natural nutrients nicotinamide and pyridoxine reverse muscle aging 💪📚🌟 www.news-medical.net/news/2024121... #Aging #MuscleHealth #StemCells #Nutrition #Regeneration #Innovation #Fitness #Science #Health #HealthyAging
Natural nutrients nicotinamide and pyridoxine reverse muscle aging
Researchers identified nicotinamide (NAM) and pyridoxine (PN) as safe, synergistic nutrients that restore muscle stem cell function, reversing age-related muscle degeneration in mice and humans.
www.news-medical.net
December 18, 2024 at 10:42 PM
Natural nutrients nicotinamide and pyridoxine reverse muscle aging 💪📚🌟 www.news-medical.net/news/2024121... #Aging #MuscleHealth #StemCells #Nutrition #Regeneration #Innovation #Fitness #Science #Health #HealthyAging
Lemons are “simply the zest!”
Per serving (1 cup, sections / ~2.5 lemons), lemons deliver 125% DV vitamin C, 347.7 mg polyphenols, 5.9 g fiber, and 10% DV vitamin B6 (pyridoxine).
Lemons have a Nutrivore Score of 477, lemon peels are 618 and lemon juice is 339!
Per serving (1 cup, sections / ~2.5 lemons), lemons deliver 125% DV vitamin C, 347.7 mg polyphenols, 5.9 g fiber, and 10% DV vitamin B6 (pyridoxine).
Lemons have a Nutrivore Score of 477, lemon peels are 618 and lemon juice is 339!
February 3, 2025 at 6:59 PM
Lemons are “simply the zest!”
Per serving (1 cup, sections / ~2.5 lemons), lemons deliver 125% DV vitamin C, 347.7 mg polyphenols, 5.9 g fiber, and 10% DV vitamin B6 (pyridoxine).
Lemons have a Nutrivore Score of 477, lemon peels are 618 and lemon juice is 339!
Per serving (1 cup, sections / ~2.5 lemons), lemons deliver 125% DV vitamin C, 347.7 mg polyphenols, 5.9 g fiber, and 10% DV vitamin B6 (pyridoxine).
Lemons have a Nutrivore Score of 477, lemon peels are 618 and lemon juice is 339!
Where do you get B vitamins?
B1 (Thiamine) 🥜🍊🍞
B2 (Riboflavin) 🥑🥛🥦🥜🍄
B3 (Niacin) 🥜🍄🥑
B5 (Pantothenic acid) 🥑🍄🌽🍅
B6 (Pyridoxine) 🥑🥜🥔🍌🍞
B7 (Biotin) 🥜🥑🌽🍞🥦🍄
B9 (Folate) 🥦🥑🍊
B10 (PABA) 🍄🍞🥦
B12 (Cobalamin) 🥛💊💉
B1 (Thiamine) 🥜🍊🍞
B2 (Riboflavin) 🥑🥛🥦🥜🍄
B3 (Niacin) 🥜🍄🥑
B5 (Pantothenic acid) 🥑🍄🌽🍅
B6 (Pyridoxine) 🥑🥜🥔🍌🍞
B7 (Biotin) 🥜🥑🌽🍞🥦🍄
B9 (Folate) 🥦🥑🍊
B10 (PABA) 🍄🍞🥦
B12 (Cobalamin) 🥛💊💉
November 17, 2025 at 9:00 AM
Where do you get B vitamins?
B1 (Thiamine) 🥜🍊🍞
B2 (Riboflavin) 🥑🥛🥦🥜🍄
B3 (Niacin) 🥜🍄🥑
B5 (Pantothenic acid) 🥑🍄🌽🍅
B6 (Pyridoxine) 🥑🥜🥔🍌🍞
B7 (Biotin) 🥜🥑🌽🍞🥦🍄
B9 (Folate) 🥦🥑🍊
B10 (PABA) 🍄🍞🥦
B12 (Cobalamin) 🥛💊💉
B1 (Thiamine) 🥜🍊🍞
B2 (Riboflavin) 🥑🥛🥦🥜🍄
B3 (Niacin) 🥜🍄🥑
B5 (Pantothenic acid) 🥑🍄🌽🍅
B6 (Pyridoxine) 🥑🥜🥔🍌🍞
B7 (Biotin) 🥜🥑🌽🍞🥦🍄
B9 (Folate) 🥦🥑🍊
B10 (PABA) 🍄🍞🥦
B12 (Cobalamin) 🥛💊💉
Revival Animal Health, LLC Voluntarily Recalls Feline Milk Replacers Due to Inconsistent Levels of Vitamins and Trace Minerals
www.fda.gov/safety/recal...
www.fda.gov/safety/recal...
Revival Animal Health, LLC Voluntarily Recalls Feline Milk Replacers Due to Inconsistent Levels of Vitamins and Trace Minerals
Revival Animal Health of Orange City, IA is recalling Breeder’s Edge® and Shelter’s Choice® Feline Milk Replacers due to low, levels of potassium, copper, folic acid, choline and/or pyridoxine (vitami...
www.fda.gov
October 6, 2026 at 9:00 AM
Revival Animal Health, LLC Voluntarily Recalls Feline Milk Replacers Due to Inconsistent Levels of Vitamins and Trace Minerals
www.fda.gov/safety/recal...
www.fda.gov/safety/recal...
same dipshits that think pyridoxine is a toxin but vitamin B6 is essential
June 22, 2026 at 11:43 PM
same dipshits that think pyridoxine is a toxin but vitamin B6 is essential
In primary school, I was a v. good speller. My teacher allowed a few of us to make up our own, more challenging lists each week. I chose the ingredients on cereal boxes: Thiamine mononitrate, pyridoxine hydrochloride, etc. They sounded hard but were mostly phonetic. I thought I was so clever. 🙄
a cartoon character walking down a sidewalk with a book in his hand
ALT: a cartoon character walking down a sidewalk with a book in his hand
media.tenor.com
November 9, 2025 at 2:06 AM
In primary school, I was a v. good speller. My teacher allowed a few of us to make up our own, more challenging lists each week. I chose the ingredients on cereal boxes: Thiamine mononitrate, pyridoxine hydrochloride, etc. They sounded hard but were mostly phonetic. I thought I was so clever. 🙄
Although P5P is not considered to be toxic, I have spoken with people who do worsen when they take it still.
Biology is anything but straightforward, and side effects can always occur in individuals even when they’re not supposed to in most people.
But I’d strongly avoid taking pyridoxine.
Biology is anything but straightforward, and side effects can always occur in individuals even when they’re not supposed to in most people.
But I’d strongly avoid taking pyridoxine.
January 14, 2025 at 12:48 PM
Although P5P is not considered to be toxic, I have spoken with people who do worsen when they take it still.
Biology is anything but straightforward, and side effects can always occur in individuals even when they’re not supposed to in most people.
But I’d strongly avoid taking pyridoxine.
Biology is anything but straightforward, and side effects can always occur in individuals even when they’re not supposed to in most people.
But I’d strongly avoid taking pyridoxine.
#Medsky🧪#publichealth #Musclebiology Could #Nicotinamide and #pyridoxine stimulate muscle #stemcell expansion and enhance regenerative capacity during aging ?
@jci-insight.bsky.social
www.jci.org/articles/vie...
www.jci.org/articles/vie...
@jci-insight.bsky.social
www.jci.org/articles/vie...
www.jci.org/articles/vie...
December 17, 2024 at 1:06 PM
#Medsky🧪#publichealth #Musclebiology Could #Nicotinamide and #pyridoxine stimulate muscle #stemcell expansion and enhance regenerative capacity during aging ?
@jci-insight.bsky.social
www.jci.org/articles/vie...
www.jci.org/articles/vie...
@jci-insight.bsky.social
www.jci.org/articles/vie...
www.jci.org/articles/vie...
Where do you get B vitamins?
B1 (Thiamine) 🥜🍊🍞
B2 (Riboflavin) 🥑🥛🥦🥜🍄
B3 (Niacin) 🥜🍄🥑
B5 (Pantothenic acid) 🥑🍄🌽🍅
B6 (Pyridoxine) 🥑🥜🥔🍌🍞
B7 (Biotin) 🥜🥑🌽🍞🥦🍄
B9 (Folate) 🥦🥑🍊
B10 (PABA) 🍄🍞🥦
B12 (Cobalamin) 🥛💊💉
B1 (Thiamine) 🥜🍊🍞
B2 (Riboflavin) 🥑🥛🥦🥜🍄
B3 (Niacin) 🥜🍄🥑
B5 (Pantothenic acid) 🥑🍄🌽🍅
B6 (Pyridoxine) 🥑🥜🥔🍌🍞
B7 (Biotin) 🥜🥑🌽🍞🥦🍄
B9 (Folate) 🥦🥑🍊
B10 (PABA) 🍄🍞🥦
B12 (Cobalamin) 🥛💊💉
November 21, 2024 at 6:00 PM
Where do you get B vitamins?
B1 (Thiamine) 🥜🍊🍞
B2 (Riboflavin) 🥑🥛🥦🥜🍄
B3 (Niacin) 🥜🍄🥑
B5 (Pantothenic acid) 🥑🍄🌽🍅
B6 (Pyridoxine) 🥑🥜🥔🍌🍞
B7 (Biotin) 🥜🥑🌽🍞🥦🍄
B9 (Folate) 🥦🥑🍊
B10 (PABA) 🍄🍞🥦
B12 (Cobalamin) 🥛💊💉
B1 (Thiamine) 🥜🍊🍞
B2 (Riboflavin) 🥑🥛🥦🥜🍄
B3 (Niacin) 🥜🍄🥑
B5 (Pantothenic acid) 🥑🍄🌽🍅
B6 (Pyridoxine) 🥑🥜🥔🍌🍞
B7 (Biotin) 🥜🥑🌽🍞🥦🍄
B9 (Folate) 🥦🥑🍊
B10 (PABA) 🍄🍞🥦
B12 (Cobalamin) 🥛💊💉
Ancient Eldritch Iron and the Pyridoxine, Pyridoxal, Pyridoxamine Ascendancy are not to be taken lightly.
Molasses ichor: "I can fix him..."
December 31, 2025 at 11:34 PM
Ancient Eldritch Iron and the Pyridoxine, Pyridoxal, Pyridoxamine Ascendancy are not to be taken lightly.
We swigged the dust in the bottom of the vitamin bottle. Calcium citrate, pyridoxine stand out.
July 31, 2026 at 5:45 PM
We swigged the dust in the bottom of the vitamin bottle. Calcium citrate, pyridoxine stand out.
Things like pyridoxine hydrochloride, niacinamide, and sodium caseinate sound scary until you spend a minute googling and find out they're Vitamin B6, Vitamin B3, and a natural milk product that even humans naturally produce respectively.
December 20, 2024 at 1:57 PM
Things like pyridoxine hydrochloride, niacinamide, and sodium caseinate sound scary until you spend a minute googling and find out they're Vitamin B6, Vitamin B3, and a natural milk product that even humans naturally produce respectively.
they add back vitamins that milling the grains removed, per the FDA's guidance for enriched flours
www.govinfo.gov/content/pkg/...
www.govinfo.gov/content/pkg/...
June 16, 2026 at 1:30 PM
they add back vitamins that milling the grains removed, per the FDA's guidance for enriched flours
www.govinfo.gov/content/pkg/...
www.govinfo.gov/content/pkg/...