While VENs might not know (or care) if a hot dog is a sandwich, I do agree with Vinny that cell types can be linked to pretty specific brain functions. And, sidebar that VENs are super frigging cool to visualize in the human brain. This RNAscope validation from a preprint we will drop very soon -

Hi #RNASky 👋 - does anyone have thoughts/experience they would like to share re: #RNAScope vs #RNA #FISH? Even better if you've tried it in plants 🌱

If you don't feel comfortable sharing publicly please DM me

Much appreciated!

Access to all code, raw and processed data, and visualization apps: research.libd.org/spatialDLPFC...
#openscience

We designed an #RNAScope/IF experiment to measure six broad cell types in the #DLPFC. We used #HALO from Indica Labs to count the occurrence of the cell types across the tissue sections 🔬 #ImmunoFlourescence (awesome work from Kelsey Montgomery)

I'm super excited to share this preprint led by @lahuuki.bsky.social on benchmarking #deconvolution methods vs orthogonal #RNAScope/IF in human brain 🧠 in collab w/@jhubiostat

If you prefer a video version, check Louise's excellent LIBD seminar 👏🏽

youtu.be/6fTnp_hcYeI

twitter.com/lahuuki/stat...

If you're around the Penn/CHOP campus on Monday 5/5 register for an ACD bio lunch and learn - you'll get a chance to eat good food and hear about our recent paper! #rnascope #chop #pennmedicine #leukodystrophy 🧪

engage.bio-techne.com/4a028e

Adipose tissue of an adult mouse after 12 weeks of high-fat diet feeding and 7 days post-traumatic brain injury, combining IF and FISH (RNAscope)."

Congratulations to Gideon van der Linden in UCD, on being selected for our next ECRN Researcher Spotlight! 🎉👏🏅

If you are using RNAscope - we strongly recommend trying HCR as an alternative. A fraction of the cost and much more transparent and flexible.